LOCUS       NM_025919               1231 bp    mRNA    linear   ROD 19-NOV-2024
DEFINITION  Mus musculus ribosomal protein L11 (Rpl11), mRNA.
ACCESSION   NM_025919
VERSION     NM_025919.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1231)
  AUTHORS   Franklin,D.A., Liu,S., Jin,A., Cui,P., Guo,Z., Arend,K.C.,
            Moorman,N.J., He,S., Wang,G.G., Wan,Y.Y. and Zhang,Y.
  TITLE     Ribosomal protein RPL11 haploinsufficiency causes anemia in mice
            via activation of the RP-MDM2-p53 pathway
  JOURNAL   J Biol Chem 299 (1), 102739 (2023)
   PUBMED   36435197
  REMARK    GeneRIF: Ribosomal protein RPL11 haploinsufficiency causes anemia
            in mice via activation of the RP-MDM2-p53 pathway.
REFERENCE   2  (bases 1 to 1231)
  AUTHORS   Li,H., Huo,Y., He,X., Yao,L., Zhang,H., Cui,Y., Xiao,H., Xie,W.,
            Zhang,D., Wang,Y., Zhang,S., Tu,H., Cheng,Y., Guo,Y., Cao,X.,
            Zhu,Y., Jiang,T., Guo,X., Qin,Y. and Sha,J.
  TITLE     A male germ-cell-specific ribosome controls male fertility
  JOURNAL   Nature 612 (7941), 725-731 (2022)
   PUBMED   36517592
REFERENCE   3  (bases 1 to 1231)
  AUTHORS   Gregorio,I., Mereu,M., Contarini,G., Bello,L., Semplicini,C.,
            Burgio,F., Russo,L., Sut,S., Dall'Acqua,S., Braghetta,P.,
            Semenza,C., Pegoraro,E., Papaleo,F., Bonaldo,P. and Cescon,M.
  TITLE     Collagen VI deficiency causes behavioral abnormalities and cortical
            dopaminergic dysfunction
  JOURNAL   Dis Model Mech 15 (9) (2022)
   PUBMED   35946603
REFERENCE   4  (bases 1 to 1231)
  AUTHORS   Doty,R.T., Yan,X., Meng,C., Lausted,C., Tian,Q. and Abkowitz,J.L.
  TITLE     Single-cell analysis of erythropoiesis in Rpl11 haploinsufficient
            mice reveals insight into the pathogenesis of Diamond-Blackfan
            anemia
  JOURNAL   Exp Hematol 97, 66-78 (2021)
   PUBMED   33631277
  REMARK    GeneRIF: Single-cell analysis of erythropoiesis in Rpl11
            haploinsufficient mice reveals insight into the pathogenesis of
            Diamond-Blackfan anemia.
REFERENCE   5  (bases 1 to 1231)
  AUTHORS   Wilkes,M.C., Siva,K., Chen,J., Varetti,G., Youn,M.Y., Chae,H.,
            Ek,F., Olsson,R., Lundback,T., Dever,D.P., Nishimura,T., Narla,A.,
            Glader,B., Nakauchi,H., Porteus,M.H., Repellin,C.E., Gazda,H.T.,
            Lin,S., Serrano,M., Flygare,J. and Sakamoto,K.M.
  TITLE     Diamond Blackfan anemia is mediated by hyperactive Nemo-like kinase
  JOURNAL   Nat Commun 11 (1), 3344 (2020)
   PUBMED   32620751
  REMARK    Publication Status: Online-Only
REFERENCE   6  (bases 1 to 1231)
  AUTHORS   Itahana,K., Mao,H., Jin,A., Itahana,Y., Clegg,H.V., Lindstrom,M.S.,
            Bhat,K.P., Godfrey,V.L., Evan,G.I. and Zhang,Y.
  TITLE     Targeted inactivation of Mdm2 RING finger E3 ubiquitin ligase
            activity in the mouse reveals mechanistic insights into p53
            regulation
  JOURNAL   Cancer Cell 12 (4), 355-366 (2007)
   PUBMED   17936560
REFERENCE   7  (bases 1 to 1231)
  AUTHORS   Panic,L., Tamarut,S., Sticker-Jantscheff,M., Barkic,M., Solter,D.,
            Uzelac,M., Grabusic,K. and Volarevic,S.
  TITLE     Ribosomal protein S6 gene haploinsufficiency is associated with
            activation of a p53-dependent checkpoint during gastrulation
  JOURNAL   Mol Cell Biol 26 (23), 8880-8891 (2006)
   PUBMED   17000767
REFERENCE   8  (bases 1 to 1231)
  AUTHORS   Yuan,X., Zhou,Y., Casanova,E., Chai,M., Kiss,E., Grone,H.J.,
            Schutz,G. and Grummt,I.
  TITLE     Genetic inactivation of the transcription factor TIF-IA leads to
            nucleolar disruption, cell cycle arrest, and p53-mediated apoptosis
  JOURNAL   Mol Cell 19 (1), 77-87 (2005)
   PUBMED   15989966
REFERENCE   9  (bases 1 to 1231)
  AUTHORS   Nishimura,M., Yokoi,N., Miki,T., Horikawa,Y., Yoshioka,H.,
            Takeda,J., Ohara,O. and Seino,S.
  TITLE     Construction of a multi-functional cDNA library specific for mouse
            pancreatic islets and its application to microarray
  JOURNAL   DNA Res 11 (5), 315-323 (2004)
   PUBMED   15747579
REFERENCE   10 (bases 1 to 1231)
  AUTHORS   Bernardi,R., Scaglioni,P.P., Bergmann,S., Horn,H.F., Vousden,K.H.
            and Pandolfi,P.P.
  TITLE     PML regulates p53 stability by sequestering Mdm2 to the nucleolus
  JOURNAL   Nat Cell Biol 6 (7), 665-672 (2004)
   PUBMED   15195100
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BX530725.11, AK008422.1, CA321948.1 and BP770399.1.
            
            On Apr 27, 2018 this sequence version replaced NM_025919.2.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BU562747.1, SRR7652917.92214.1
                                           [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN00849374,
                                           SAMN00849375 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-22                BX530725.11        26087-26108         c
            23-616              AK008422.1         3-596
            617-795             CA321948.1         559-737
            796-819             BX530725.11        22460-22483         c
            820-1231            BP770399.1         1-412               c
FEATURES             Location/Qualifiers
     source          1..1231
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="4"
                     /map="4 68.34 cM"
     gene            1..1231
                     /gene="Rpl11"
                     /gene_synonym="2010203J19Rik"
                     /note="ribosomal protein L11"
                     /db_xref="GeneID:67025"
                     /db_xref="MGI:MGI:1914275"
     exon            1..46
                     /gene="Rpl11"
                     /gene_synonym="2010203J19Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            47..197
                     /gene="Rpl11"
                     /gene_synonym="2010203J19Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            198..304
                     /gene="Rpl11"
                     /gene_synonym="2010203J19Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            305..436
                     /gene="Rpl11"
                     /gene_synonym="2010203J19Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            437..547
                     /gene="Rpl11"
                     /gene_synonym="2010203J19Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            548..1210
                     /gene="Rpl11"
                     /gene_synonym="2010203J19Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      595..600
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Rpl11"
                     /gene_synonym="2010203J19Rik"
                     /note="hexamer: AATAAA"
     polyA_site      617
                     /gene="Rpl11"
                     /gene_synonym="2010203J19Rik"
                     /note="major polyA site"
     regulatory      1183..1188
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Rpl11"
                     /gene_synonym="2010203J19Rik"
                     /note="hexamer: ATTAAA"
     polyA_site      1210
                     /gene="Rpl11"
                     /gene_synonym="2010203J19Rik"
ORIGIN      
        1 acggggccgg aagtctccct ctctcttcct gttctccacc atggcgcaag atcaagggga
       61 aaaggagaac cccatgcggg aactgcgcat ccgcaagctc tgcctcaata tctgcgtcgg
      121 ggagagcgga gacagactga cccgggcagc caaggtgttg gagcagctca caggccagac
      181 cccggtgttc tccaaagcta gatacactgt caggtccttt ggcatccgga gaaatgagaa
      241 gattgctgtt cactgcacag tccgcggagc caaggcagag gaaattctgg agaaaggcct
      301 gaaggtgcgg gagtatgagt tgcggaaaaa taacttctcg gatactggaa actttggttt
      361 tggaattcaa gaacacattg acctgggcat caaatacgac ccaagcattg ggatctacgg
      421 cctggacttc tatgtggtgc tgggtaggcc agggttcagc atcgcagaca agaagcgcag
      481 aacaggctgc attggggcca aacacagaat cagcaaggag gaggccatgc gctggttcca
      541 gcagaagtac gatggaatca tccttcctgg aaaataaact tgatccaaaa agctaataaa
      601 attttctcag aaatgcatgt tacagttgtg tgtttgtgaa aggcgcgtgg cctcattcag
      661 atcctgggac cacaagcact taaagaaagc ctcgatgaga attgctggtg gcggcggcag
      721 cctgcgtcct ggactccagt gtctccccac agctgagact gagcattgag tgccctgtgg
      781 gtgggctgtg gtgcagaggt cctttaagtg ggttttgaga ggtattgggt tggttagggt
      841 ttggatttgg ttgtaattaa gggctgggac aatgtcccag tcccagcagg tgtcccttgt
      901 ttgtgacttg gtgtgtggtg aagggaccac agcttctggt gtggtggtaa agactatttt
      961 ggctttgttc atagttgagt tgcatttaaa atgacacagt tgggagggag gccttgttag
     1021 gaaggaagtc tcacaggcaa attgtcggat tagtcctccc ttgattagct atggtaacct
     1081 ggagcagatc tgtctctttc acggaagcaa tcatcagaca actactaggc gtgtgagcac
     1141 ttgaattttt ttttgtgtgt tttgttcgtg gaatcctaac acattaaaac ttggcttgtt
     1201 ttggtgtgaa aaaaaaaaaa aaaaaaaaaa a
//
