LOCUS       NM_011287                718 bp    mRNA    linear   ROD 12-JUN-2024
DEFINITION  Mus musculus ribosomal protein L10A (Rpl10a), transcript variant 1,
            mRNA.
ACCESSION   NM_011287
VERSION     NM_011287.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 718)
  AUTHORS   Li,H., Huo,Y., He,X., Yao,L., Zhang,H., Cui,Y., Xiao,H., Xie,W.,
            Zhang,D., Wang,Y., Zhang,S., Tu,H., Cheng,Y., Guo,Y., Cao,X.,
            Zhu,Y., Jiang,T., Guo,X., Qin,Y. and Sha,J.
  TITLE     A male germ-cell-specific ribosome controls male fertility
  JOURNAL   Nature 612 (7941), 725-731 (2022)
   PUBMED   36517592
REFERENCE   2  (bases 1 to 718)
  AUTHORS   Genuth,N.R., Shi,Z., Kunimoto,K., Hung,V., Xu,A.F., Kerr,C.H.,
            Tiu,G.C., Oses-Prieto,J.A., Salomon-Shulman,R.E.A., Axelrod,J.D.,
            Burlingame,A.L., Loh,K.M. and Barna,M.
  TITLE     A stem cell roadmap of ribosome heterogeneity reveals a function
            for RPL10A in mesoderm production
  JOURNAL   Nat Commun 13 (1), 5491 (2022)
   PUBMED   36123354
  REMARK    GeneRIF: A stem cell roadmap of ribosome heterogeneity reveals a
            function for RPL10A in mesoderm production.
            Publication Status: Online-Only
REFERENCE   3  (bases 1 to 718)
  AUTHORS   Hofmeister,A., Thomassen,M.C., Markert,S., Marquardt,A.,
            Preussner,M., Russwurm,M., Schermuly,R.T., Steinhoff,U.,
            Grone,H.J., Hoyer,J., Humphreys,B.D. and Grgic,I.
  TITLE     Development of a new macrophage-specific TRAP mouse (MacTRAP) and
            definition of the renal macrophage translational signature
  JOURNAL   Sci Rep 10 (1), 7519 (2020)
   PUBMED   32372032
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 718)
  AUTHORS   Khatter,H., Myasnikov,A.G., Natchiar,S.K. and Klaholz,B.P.
  TITLE     Structure of the human 80S ribosome
  JOURNAL   Nature 520 (7549), 640-645 (2015)
   PUBMED   25901680
REFERENCE   5  (bases 1 to 718)
  AUTHORS   Kondrashov,N., Pusic,A., Stumpf,C.R., Shimizu,K., Hsieh,A.C.,
            Ishijima,J., Shiroishi,T. and Barna,M.
  TITLE     Ribosome-mediated specificity in Hox mRNA translation and
            vertebrate tissue patterning
  JOURNAL   Cell 145 (3), 383-397 (2011)
   PUBMED   21529712
REFERENCE   6  (bases 1 to 718)
  AUTHORS   Kim,S.C., Sprung,R., Chen,Y., Xu,Y., Ball,H., Pei,J., Cheng,T.,
            Kho,Y., Xiao,H., Xiao,L., Grishin,N.V., White,M., Yang,X.J. and
            Zhao,Y.
  TITLE     Substrate and functional diversity of lysine acetylation revealed
            by a proteomics survey
  JOURNAL   Mol Cell 23 (4), 607-618 (2006)
   PUBMED   16916647
REFERENCE   7  (bases 1 to 718)
  AUTHORS   Trinidad,J.C., Specht,C.G., Thalhammer,A., Schoepfer,R. and
            Burlingame,A.L.
  TITLE     Comprehensive identification of phosphorylation sites in
            postsynaptic density preparations
  JOURNAL   Mol Cell Proteomics 5 (5), 914-922 (2006)
   PUBMED   16452087
REFERENCE   8  (bases 1 to 718)
  AUTHORS   Stryke,D., Kawamoto,M., Huang,C.C., Johns,S.J., King,L.A.,
            Harper,C.A., Meng,E.C., Lee,R.E., Yee,A., L'Italien,L.,
            Chuang,P.T., Young,S.G., Skarnes,W.C., Babbitt,P.C. and Ferrin,T.E.
  TITLE     BayGenomics: a resource of insertional mutations in mouse embryonic
            stem cells
  JOURNAL   Nucleic Acids Res 31 (1), 278-281 (2003)
   PUBMED   12520002
REFERENCE   9  (bases 1 to 718)
  AUTHORS   Fisicaro,N., Katerelos,M., Williams,J., Power,D., D'Apice,A. and
            Pearse,M.
  TITLE     Identification of genes downregulated in the thymus by
            cyclosporin-A: preliminary characterization of clone CSA-19
  JOURNAL   Mol Immunol 32 (8), 565-572 (1995)
   PUBMED   7609734
REFERENCE   10 (bases 1 to 718)
  AUTHORS   Kumar,S., Tomooka,Y. and Noda,M.
  TITLE     Identification of a set of genes with developmentally
            down-regulated expression in the mouse brain
  JOURNAL   Biochem Biophys Res Commun 185 (3), 1155-1161 (1992)
   PUBMED   1378265
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            CT025652.7.
            
            On Mar 5, 2022 this sequence version replaced NM_011287.2.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK151172.1, DV062011.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-36                CT025652.7         34424-34459         c
            37-111              CT025652.7         34157-34231         c
            112-192             CT025652.7         33995-34075         c
            193-341             CT025652.7         33520-33668         c
            342-514             CT025652.7         32345-32517         c
            515-718             CT025652.7         32009-32212         c
FEATURES             Location/Qualifiers
     source          1..718
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="17"
                     /map="17 14.65 cM"
     gene            1..718
                     /gene="Rpl10a"
                     /gene_synonym="CsA-19; Nedd6"
                     /note="ribosomal protein L10A"
                     /db_xref="GeneID:19896"
                     /db_xref="MGI:MGI:1343877"
     exon            1..36
                     /gene="Rpl10a"
                     /gene_synonym="CsA-19; Nedd6"
                     /inference="alignment:Splign:2.1.0"
     CDS             32..685
                     /gene="Rpl10a"
                     /gene_synonym="CsA-19; Nedd6"
                     /EC_number="3.6.5.3"
                     /note="isoform 1 is encoded by transcript variant 1; 60S
                     ribosomal protein L10a; NEDD-6; neural precursor cell
                     expressed developmentally down-regulated protein 6; large
                     ribosomal subunit protein uL1"
                     /codon_start=1
                     /product="large ribosomal subunit protein uL1 isoform 1"
                     /protein_id="NP_035417.2"
                     /db_xref="CCDS:CCDS28576.1"
                     /db_xref="GeneID:19896"
                     /db_xref="MGI:MGI:1343877"
                     /translation="MSSKVSRDTLYEAVREVLHGNQRKRRKFLETVELQISLKNYDPQ
                     KDKRFSGTVRLKSTPRPKFSVCVLGDQQHCDEAKAVDIPHMDIEALKKLNKNKKLVKK
                     LAKKYDAFLASESLIKQIPRILGPGLNKAGKFPSLLTHNENMVAKVDEVKSTIKFQMK
                     KVLCLAVAVGHVKMTDDELVYNIHLAVNFLVSLLKKNWQNVRALYIKSTMGKPQRLY"
     exon            37..111
                     /gene="Rpl10a"
                     /gene_synonym="CsA-19; Nedd6"
                     /inference="alignment:Splign:2.1.0"
     exon            112..192
                     /gene="Rpl10a"
                     /gene_synonym="CsA-19; Nedd6"
                     /inference="alignment:Splign:2.1.0"
     exon            193..341
                     /gene="Rpl10a"
                     /gene_synonym="CsA-19; Nedd6"
                     /inference="alignment:Splign:2.1.0"
     exon            342..514
                     /gene="Rpl10a"
                     /gene_synonym="CsA-19; Nedd6"
                     /inference="alignment:Splign:2.1.0"
     exon            515..718
                     /gene="Rpl10a"
                     /gene_synonym="CsA-19; Nedd6"
                     /inference="alignment:Splign:2.1.0"
     regulatory      694..699
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Rpl10a"
                     /gene_synonym="CsA-19; Nedd6"
                     /note="hexamer: AATAAA"
     polyA_site      718
                     /gene="Rpl10a"
                     /gene_synonym="CsA-19; Nedd6"
                     /note="major polyA site"
ORIGIN      
        1 cttctttccg gtttccgcgg cagccgcagc catgagcagc aaagtctcac gcgacaccct
       61 gtacgaggcg gtgcgggaag tcctgcacgg gaaccagcgc aagcgccgca agtttctgga
      121 gacggtggag ctgcagatca gcctgaagaa ctacgaccct cagaaggaca aacgtttctc
      181 gggcaccgtc aggctcaagt ccaccccacg ccccaagttc tcggtgtgcg ttctggggga
      241 ccagcagcac tgtgatgaag ccaaggccgt ggatatcccc cacatggaca tcgaggcgct
      301 caagaagctt aacaaaaaca agaagttggt caagaagctg gctaagaagt acgatgcctt
      361 tttggcctct gagtctctga ttaagcagat cccacgtatc ctgggcccag gcctaaacaa
      421 ggctggcaag ttcccctccc tgctgacaca caatgaaaac atggtggcca aagtggatga
      481 ggtgaaatcg acaatcaagt tccagatgaa gaaggtgctg tgtttggccg tcgctgttgg
      541 ccacgtgaag atgaccgatg atgagctagt ctacaacatt catctggctg tcaatttctt
      601 ggtgtccttg cttaagaaaa actggcaaaa cgtgcgggct ctgtacatca agagcaccat
      661 gggcaagccc cagcgtctgt attaggatgc tccaataaac ctcactgctg ccactcag
//
