LOCUS       NM_028003               2260 bp    mRNA    linear   ROD 09-FEB-2025
DEFINITION  Mus musculus RNA polymerase II associated protein 3 (Rpap3), mRNA.
ACCESSION   NM_028003
VERSION     NM_028003.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2260)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 2260)
  AUTHORS   Maurizy,C., Abeza,C., Lemmers,B., Gabola,M., Longobardi,C.,
            Pinet,V., Ferrand,M., Paul,C., Bremond,J., Langa,F., Gerbe,F.,
            Jay,P., Verheggen,C., Tinari,N., Helmlinger,D., Lattanzio,R.,
            Bertrand,E., Hahne,M. and Pradet-Balade,B.
  TITLE     The HSP90/R2TP assembly chaperone promotes cell proliferation in
            the intestinal epithelium
  JOURNAL   Nat Commun 12 (1), 4810 (2021)
   PUBMED   34376666
  REMARK    Erratum:[Nat Commun. 2022 Oct 19;13(1):6200. doi:
            10.1038/s41467-022-33519-y.. PMID: 36261420]
            Publication Status: Online-Only
REFERENCE   3  (bases 1 to 2260)
  AUTHORS   Stryke,D., Kawamoto,M., Huang,C.C., Johns,S.J., King,L.A.,
            Harper,C.A., Meng,E.C., Lee,R.E., Yee,A., L'Italien,L.,
            Chuang,P.T., Young,S.G., Skarnes,W.C., Babbitt,P.C. and Ferrin,T.E.
  TITLE     BayGenomics: a resource of insertional mutations in mouse embryonic
            stem cells
  JOURNAL   Nucleic Acids Res 31 (1), 278-281 (2003)
   PUBMED   12520002
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AK009765.1.
            
            On Apr 6, 2007 this sequence version replaced NM_028003.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK009765.1, BC004046.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN00849374,
                                           SAMN00849375 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-2260              AK009765.1         2-2261
FEATURES             Location/Qualifiers
     source          1..2260
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="15"
                     /map="15 53.54 cM"
     gene            1..2260
                     /gene="Rpap3"
                     /gene_synonym="2310042P20Rik; D15Ertd682e"
                     /note="RNA polymerase II associated protein 3"
                     /db_xref="GeneID:71919"
                     /db_xref="MGI:MGI:1277218"
     exon            1..73
                     /gene="Rpap3"
                     /gene_synonym="2310042P20Rik; D15Ertd682e"
                     /inference="alignment:Splign:2.1.0"
     exon            74..241
                     /gene="Rpap3"
                     /gene_synonym="2310042P20Rik; D15Ertd682e"
                     /inference="alignment:Splign:2.1.0"
     CDS             89..2071
                     /gene="Rpap3"
                     /gene_synonym="2310042P20Rik; D15Ertd682e"
                     /codon_start=1
                     /product="RNA polymerase II-associated protein 3"
                     /protein_id="NP_082279.1"
                     /db_xref="CCDS:CCDS27782.1"
                     /db_xref="GeneID:71919"
                     /db_xref="MGI:MGI:1277218"
                     /translation="MTSASKAVELQLQVKHNAEELQDFMRDLEHWEKDMKEKDLELRR
                     QGGVAEENLPPIRNGNFRKKKKKGKAKESSRKTKEENTKNRIKSYDYDAWAKLDVDRI
                     LDELDKEDSTHDSLSQESESDEDGIRVDSQKALVLKEKGNKYFKQGKYDEAIECYTKG
                     MDADPYNPVLPTNRASAYFRLKKFAVAESDCNLAIALSRTYTKAYARRGAARFALQKL
                     EDARKDYEKVLELEPDNFEATNELRKINQALTSKENSGPGAAAAAESKPAAGESKPTG
                     GQQGRQKAIAEKDLGNGFFKEGKYEQAIECYTRGIAADRTNALLPANRAMAYLKIQRY
                     EEAERDCTQAIVLDGSYSKAFARRGTARTFLGKINEAKQDFETVLLLEPGNKQAATEL
                     SRIKKELIEKGHWDDVFLDSTQRHHVVKAVDNPPRGSPKALKKVFIEETGNLIETVDA
                     PDSSATVPESDRATAAVGTGTKKNPSEGVSLPAGDRPRAKVLKIEAVSDTSAPQAQVG
                     VKQDARQPGSEKASVRAEQMPGQLAAAGLPPVPANSFQLESDFRQLRSSPEMLYQYVK
                     NIEPSLYPKLFQKNLDPDVFNQIIKILHDFYIEREKPALIFEVLERLSQLRRFDMAVM
                     FMSGPERKLTNVLFNHLEKSDLKEDSVEELKKRYGG"
     exon            242..385
                     /gene="Rpap3"
                     /gene_synonym="2310042P20Rik; D15Ertd682e"
                     /inference="alignment:Splign:2.1.0"
     exon            386..508
                     /gene="Rpap3"
                     /gene_synonym="2310042P20Rik; D15Ertd682e"
                     /inference="alignment:Splign:2.1.0"
     exon            509..636
                     /gene="Rpap3"
                     /gene_synonym="2310042P20Rik; D15Ertd682e"
                     /inference="alignment:Splign:2.1.0"
     exon            637..758
                     /gene="Rpap3"
                     /gene_synonym="2310042P20Rik; D15Ertd682e"
                     /inference="alignment:Splign:2.1.0"
     exon            759..829
                     /gene="Rpap3"
                     /gene_synonym="2310042P20Rik; D15Ertd682e"
                     /inference="alignment:Splign:2.1.0"
     exon            830..958
                     /gene="Rpap3"
                     /gene_synonym="2310042P20Rik; D15Ertd682e"
                     /inference="alignment:Splign:2.1.0"
     exon            959..1086
                     /gene="Rpap3"
                     /gene_synonym="2310042P20Rik; D15Ertd682e"
                     /inference="alignment:Splign:2.1.0"
     exon            1087..1208
                     /gene="Rpap3"
                     /gene_synonym="2310042P20Rik; D15Ertd682e"
                     /inference="alignment:Splign:2.1.0"
     exon            1209..1279
                     /gene="Rpap3"
                     /gene_synonym="2310042P20Rik; D15Ertd682e"
                     /inference="alignment:Splign:2.1.0"
     exon            1280..1378
                     /gene="Rpap3"
                     /gene_synonym="2310042P20Rik; D15Ertd682e"
                     /inference="alignment:Splign:2.1.0"
     exon            1379..1599
                     /gene="Rpap3"
                     /gene_synonym="2310042P20Rik; D15Ertd682e"
                     /inference="alignment:Splign:2.1.0"
     exon            1600..1786
                     /gene="Rpap3"
                     /gene_synonym="2310042P20Rik; D15Ertd682e"
                     /inference="alignment:Splign:2.1.0"
     exon            1787..1884
                     /gene="Rpap3"
                     /gene_synonym="2310042P20Rik; D15Ertd682e"
                     /inference="alignment:Splign:2.1.0"
     exon            1885..1985
                     /gene="Rpap3"
                     /gene_synonym="2310042P20Rik; D15Ertd682e"
                     /inference="alignment:Splign:2.1.0"
     exon            1986..2260
                     /gene="Rpap3"
                     /gene_synonym="2310042P20Rik; D15Ertd682e"
                     /inference="alignment:Splign:2.1.0"
     polyA_site      2260
                     /gene="Rpap3"
                     /gene_synonym="2310042P20Rik; D15Ertd682e"
                     /note="putative"
ORIGIN      
        1 gcagacctcc ggcggtggtg taggacgccg tgcgtctccc tggagccggt gaggttggtg
       61 gccgccgtgg cggacttggc aggacacgat gacttcggcg agtaaggcag ttgagttgca
      121 gctccaggtg aaacacaacg cagaggagct gcaggacttc atgagggact tggagcactg
      181 ggagaaggac atgaaggaga aggacctgga gctgagaaga cagggtggcg ttgccgagga
      241 gaatttacct cctattcgaa atgggaattt tagaaagaag aagaagaaag gcaaagctaa
      301 agagtcttcc agaaaaacca aagaagaaaa cacgaaaaac agaataaaat cttacgacta
      361 tgatgcctgg gcaaaacttg atgtggacag gattctcgac gagcttgaca aagaagacag
      421 cacccacgat tctctgtccc aggagtcaga gtcggatgaa gatggcattc gtgtggattc
      481 ccagaaagct cttgttctaa aagaaaaggg caataagtac ttcaagcaag gaaagtacga
      541 tgaagccatt gaatgctaca cgaaaggcat ggatgctgac ccctacaatc ccgtgctgcc
      601 aacaaacaga gcgtcggctt acttcagact gaaaaagttt gctgttgctg agtctgactg
      661 taacttggcc atcgccttga gcaggactta caccaaggcg tacgccaggc gaggtgcagc
      721 tcggtttgct ctgcagaagt tagaggacgc cagaaaagat tatgagaaag tgttagaact
      781 ggagccagat aactttgaag caacaaatga actcaggaaa attaatcagg ctttgacgtc
      841 caaggaaaac tcgggtcctg gagcagctgc tgctgcggag agtaagccag ctgcagggga
      901 gagcaaacca accggtggtc agcagggcag gcagaaggcc atagcggaga aagacctggg
      961 caacggattt ttcaaagagg ggaaatacga gcaagcaatt gagtgctaca cccgcgggat
     1021 agcagcggac cgcaccaacg ccctgctgcc agctaacaga gcgatggcct atctcaagat
     1081 tcagagatat gaagaagctg aaagagactg cacacaagct atcgtactag atggctcata
     1141 ctcaaaagcg tttgccagaa gaggaacagc aaggacattt ttgggaaaga tcaatgaggc
     1201 caagcaagac tttgagactg ttttacttct ggaacctgga aataagcaag cggcgaccga
     1261 gctttccaga atcaaaaagg aactaataga gaaaggccac tgggatgatg tcttccttga
     1321 ctccacacag agacaccatg tggtgaaagc tgtggataat cctcctcggg gctcccctaa
     1381 agcactcaag aaggttttta ttgaagaaac tggcaatttg atagagactg ttgatgcacc
     1441 agatagttct gccactgtcc ctgagagtga tcgagcaacg gcagctgtgg gcactggaac
     1501 caagaagaat ccaagcgagg gcgtctctct gcctgcaggg gataggccaa gagctaaagt
     1561 gttgaaaata gaagcagtca gtgacacttc agccccacaa gcacaggtgg gggtgaagca
     1621 ggatgcgcgt cagcctggga gtgagaaggc ctccgtgagg gcagagcaga tgccgggtca
     1681 gctggccgct gctggtctgc ctccagttcc tgccaactcc ttccagctcg agtctgattt
     1741 cagacagttg agaagttccc cagagatgct gtatcagtat gtaaagaata tcgaaccatc
     1801 tttgtatccg aagttgtttc agaaaaacct agatccagat gtattcaatc aaatcattaa
     1861 gattctacac gacttttaca ttgagaggga aaagccagct ctcatctttg aagtcttaga
     1921 acgactttct cagctgagaa ggtttgacat ggcggtgatg tttatgtcag gacctgagag
     1981 aaagcttaca aatgtattat tcaatcactt agaaaaatca gacctgaagg aagattctgt
     2041 tgaagaactc aagaaaagat acggcggctg acctccatga tcggacgttg ccgcctctgt
     2101 gtacattatt ttccttactg aaatcaagtg tttgactttt tacaaaagtg aaaccttacc
     2161 cgagaggagt ttcctatctc tggatggcag ttgattcact gtaagtgttc tgtggcctaa
     2221 ctagtgagag atgcttcaaa taaactaagt ttttatgagt
//
