LOCUS       NM_011284               1782 bp    mRNA    linear   ROD 24-APR-2024
DEFINITION  Mus musculus replication protein A2 (Rpa2), mRNA.
ACCESSION   NM_011284
VERSION     NM_011284.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1782)
  AUTHORS   Zhang,J., Ruiz,M., Bergh,P.O., Henricsson,M., Stojanovic,N.,
            Devkota,R., Henn,M., Bohlooly-Y,M., Hernandez-Hernandez,A.,
            Alsheimer,M., Boren,J., Pilon,M. and Shibuya,H.
  TITLE     Regulation of meiotic telomere dynamics through membrane fluidity
            promoted by AdipoR2-ELOVL2
  JOURNAL   Nat Commun 15 (1), 2315 (2024)
   PUBMED   38485951
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1782)
  AUTHORS   Jiang,X., Cheng,Y., Zhu,Y., Xu,C., Li,Q., Xing,X., Li,W., Zou,J.,
            Meng,L., Azhar,M., Cao,Y., Tong,X., Qin,W., Zhu,X. and Bao,J.
  TITLE     Maternal NAT10 orchestrates oocyte meiotic cell-cycle progression
            and maturation in mice
  JOURNAL   Nat Commun 14 (1), 3729 (2023)
   PUBMED   37349316
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 1782)
  AUTHORS   Yang,Y., Xu,W., Gao,F., Wen,C., Zhao,S., Yu,Y., Jiao,W., Mi,X.,
            Qin,Y., Chen,Z.J. and Zhao,S.
  TITLE     Transcription-replication conflicts in primordial germ cells
            necessitate the Fanconi anemia pathway to safeguard genome
            stability
  JOURNAL   Proc Natl Acad Sci U S A 119 (34), e2203208119 (2022)
   PUBMED   35969748
REFERENCE   4  (bases 1 to 1782)
  AUTHORS   Guan,Y., Lin,H., Leu,N.A., Ruthel,G., Fuchs,S.Y., Busino,L., Luo,M.
            and Wang,P.J.
  TITLE     SCF ubiquitin E3 ligase regulates DNA double-strand breaks in early
            meiotic recombination
  JOURNAL   Nucleic Acids Res 50 (9), 5129-5144 (2022)
   PUBMED   35489071
REFERENCE   5  (bases 1 to 1782)
  AUTHORS   Dong,M.Z., Ouyang,Y.C., Gao,S.C., Ma,X.S., Hou,Y., Schatten,H.,
            Wang,Z.B. and Sun,Q.Y.
  TITLE     PPP4C facilitates homologous recombination DNA repair by
            dephosphorylating PLK1 during early embryo development
  JOURNAL   Development 149 (10) (2022)
   PUBMED   35546066
REFERENCE   6  (bases 1 to 1782)
  AUTHORS   Stryke,D., Kawamoto,M., Huang,C.C., Johns,S.J., King,L.A.,
            Harper,C.A., Meng,E.C., Lee,R.E., Yee,A., L'Italien,L.,
            Chuang,P.T., Young,S.G., Skarnes,W.C., Babbitt,P.C. and Ferrin,T.E.
  TITLE     BayGenomics: a resource of insertional mutations in mouse embryonic
            stem cells
  JOURNAL   Nucleic Acids Res 31 (1), 278-281 (2003)
   PUBMED   12520002
REFERENCE   7  (bases 1 to 1782)
  AUTHORS   Lipkin,S.M., Moens,P.B., Wang,V., Lenzi,M., Shanmugarajah,D.,
            Gilgeous,A., Thomas,J., Cheng,J., Touchman,J.W., Green,E.D.,
            Schwartzberg,P., Collins,F.S. and Cohen,P.E.
  TITLE     Meiotic arrest and aneuploidy in MLH3-deficient mice
  JOURNAL   Nat Genet 31 (4), 385-390 (2002)
   PUBMED   12091911
REFERENCE   8  (bases 1 to 1782)
  AUTHORS   Ishibashi,T., Kimura,S., Furukawa,T., Hatanaka,M., Hashimoto,J. and
            Sakaguchi,K.
  TITLE     Two types of replication protein A 70 kDa subunit in rice, Oryza
            sativa: molecular cloning, characterization, and cellular & tissue
            distribution
  JOURNAL   Gene 272 (1-2), 335-343 (2001)
   PUBMED   11470540
REFERENCE   9  (bases 1 to 1782)
  AUTHORS   Hwang,S.Y., Oh,B., Knowles,B.B., Solter,D. and Lee,J.S.
  TITLE     Expression of genes involved in mammalian meiosis during the
            transition from egg to embryo
  JOURNAL   Mol Reprod Dev 59 (2), 144-158 (2001)
   PUBMED   11389549
REFERENCE   10 (bases 1 to 1782)
  AUTHORS   Nakagawa,M., Tsukada,S., Soma,T., Shimizu,Y., Miyake,S.,
            Iwamatsu,A. and Sugiyama,H.
  TITLE     cDNA cloning of the murine 30-kDa protein homologous to the 32-kDa
            subunit of human replication protein A
  JOURNAL   Nucleic Acids Res 19 (15), 4292 (1991)
   PUBMED   1908076
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AK168680.1.
            
            [WARNING] On Apr 26, 2024 this sequence was replaced by
            NM_011284.4.
            
            On Jul 23, 2006 this sequence version replaced NM_011284.2.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK168680.1, BC004578.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1782
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="4"
                     /map="4 65.88 cM"
     gene            1..1782
                     /gene="Rpa2"
                     /gene_synonym="Rf-A2; RPA34"
                     /note="replication protein A2"
                     /db_xref="GeneID:19891"
                     /db_xref="MGI:MGI:1339939"
     exon            1..107
                     /gene="Rpa2"
                     /gene_synonym="Rf-A2; RPA34"
                     /inference="alignment:Splign:2.1.0"
     exon            108..214
                     /gene="Rpa2"
                     /gene_synonym="Rf-A2; RPA34"
                     /inference="alignment:Splign:2.1.0"
     exon            215..316
                     /gene="Rpa2"
                     /gene_synonym="Rf-A2; RPA34"
                     /inference="alignment:Splign:2.1.0"
     exon            317..430
                     /gene="Rpa2"
                     /gene_synonym="Rf-A2; RPA34"
                     /inference="alignment:Splign:2.1.0"
     exon            431..505
                     /gene="Rpa2"
                     /gene_synonym="Rf-A2; RPA34"
                     /inference="alignment:Splign:2.1.0"
     exon            506..622
                     /gene="Rpa2"
                     /gene_synonym="Rf-A2; RPA34"
                     /inference="alignment:Splign:2.1.0"
     exon            623..730
                     /gene="Rpa2"
                     /gene_synonym="Rf-A2; RPA34"
                     /inference="alignment:Splign:2.1.0"
     exon            731..825
                     /gene="Rpa2"
                     /gene_synonym="Rf-A2; RPA34"
                     /inference="alignment:Splign:2.1.0"
     exon            826..1782
                     /gene="Rpa2"
                     /gene_synonym="Rf-A2; RPA34"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1499..1504
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Rpa2"
                     /gene_synonym="Rf-A2; RPA34"
                     /note="hexamer: GATAAA"
     polyA_site      1519
                     /gene="Rpa2"
                     /gene_synonym="Rf-A2; RPA34"
                     /note="major polyA site"
ORIGIN      
        1 gaaggctgcc acgccagagc ggcacagagt tcccaagtgt tcttagtttt cgtgtccgag
       61 cgtcttgggc cgctctctcc ggagaactgc gaccaggatg tggaatagcg gattcgaaag
      121 cttcagcagc tccacctatg gcggagcagg cggctacacg cagtcccccg gtggcttcgg
      181 gtcgcccaca ccgtcgcagg cggagaagaa atcgagagtc cgagcccagc atattgtgcc
      241 ctgtaccata tcccagctgc tttctgctac tctgactgat gaagtgttca gaattggaga
      301 tgtcgagatt tcacaggtca ctattgtggg gataatcaga catgcggaga aggctccaac
      361 caacattgtt tacaagatag acgatatgac agctccgccc atggatgttc gtcagtgggt
      421 tgacacggat gatgccagtg gtgagaacgc cgtggttcct cccgaaacat acgtgaaagt
      481 cgctggtcac ctcaggtctt tccagaacaa aaagagcttg gtggccttta agatcattcc
      541 tctggaagac atgaatgagt tcaccgcaca catcctggaa gtggtcaatt cacacatgat
      601 gctcagcaag cccaacagcc aggcctctgc agggagacca tcgatgagca acccaggaat
      661 gagtgagccg gggaacttca gcgggaataa cttcatgcca gcaaatggcc tcactgtggt
      721 ccaaaaccag gtgctgaatt tgatcaaggc ttgcccaaga cctgaaggcc tgaacttcca
      781 ggacctcagg agccagctcc agcatatgcc tgttccctca atcaagcaag cagtggattt
      841 tctgtgcaac gagggccaca tttactctac tgtggacgac gatcacttta agtctacaga
      901 tgcagagtga ctggagtttc ctgggtgcct ggaatctgtc cagctgggcc tgtgttcctc
      961 tgtcggcccc agctctgcgg gctttggcca gaggcttcta ggacagaact ttgctgtaga
     1021 aggtctcact cagctgaagt ccttttggaa cttagtgctc tctgttttgt tgcttgttgt
     1081 ttagaggttc agagggagat agacagttga gaaggaagta aaccaggact ggatttcttg
     1141 taagaaattc caataagcta gtcaggactc caggatgggt ggtcggaatt gaaagaggaa
     1201 cactgccaag atgtcagggc agggcttcag cttgcttgag agcgactgtt ctccaaggct
     1261 tcgtgttgag gacaagcact gctagggcca agggccaaag aagaacctac caccctctgc
     1321 cagtttgcgc tgccctctgg gtctgcgggg ttactttcgg aattgcactt tccttccctt
     1381 gtcttgcccg ccgtgggaag gaggtttaag tgagcctgag gttctgacct ggaggcctcg
     1441 tgcggctgag agaaagaaat gttattgcgt ggtctgtaat ataagtgttc atatgtttga
     1501 taaaacagtt cgattgtaat agcttctgaa atgttggttt tatttttagc gcttacttac
     1561 tgtgtgagtg tggaagtcag aggacagctt ggtggagtct gctttctctt tgtacagtgt
     1621 acagagtcac cttctatcgt gtattccagg ggttcaactc tggtcatcag gcttattggg
     1681 gggttgtggg tgtgcatagc atgtgccatg gccaccgcag attgtgacta gaccttgagc
     1741 tggggctaca gctcacagta gtaaagcact tgcctgccat cc
//
