LOCUS       NM_001164767            4726 bp    mRNA    linear   ROD 31-DEC-2024
DEFINITION  Mus musculus roundabout guidance receptor 3 (Robo3), mRNA.
ACCESSION   NM_001164767 XM_001476840 XM_001478301
VERSION     NM_001164767.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 4726)
  AUTHORS   Balekoglu,N., Michaud,J.F., Sauve,R., Ayinde,K.S., Lin,S., Liu,Y.,
            Kramer,D.A., Zhang,K., Steffen,A., Stradal,T., Angers,S., Chen,B.,
            Yam,P.T. and Charron,F.
  TITLE     The WAVE regulatory complex interacts with Boc and is required for
            Shh-mediated axon guidance
  JOURNAL   iScience 27 (12), 111333 (2024)
   PUBMED   39640588
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4726)
  AUTHORS   Hochbaum,D.R., Hulshof,L., Urke,A., Wang,W., Dubinsky,A.C.,
            Farnsworth,H.C., Hakim,R., Lin,S., Kleinberg,G., Robertson,K.,
            Park,C., Solberg,A., Yang,Y., Baynard,C., Nadaf,N.M., Beron,C.C.,
            Girasole,A.E., Chantranupong,L., Cortopassi,M.D., Prouty,S.,
            Geistlinger,L., Banks,A.S., Scanlan,T.S., Datta,S.R.,
            Greenberg,M.E., Boulting,G.L., Macosko,E.Z. and Sabatini,B.L.
  TITLE     Thyroid hormone remodels cortex to coordinate body-wide metabolism
            and exploration
  JOURNAL   Cell 187 (20), 5679-5697 (2024)
   PUBMED   39178853
REFERENCE   3  (bases 1 to 4726)
  AUTHORS   Mehta,K., Daghsni,M., Raeisossadati,R., Xu,Z., Davis,E.,
            Naidich,A., Wang,B., Tao,S., Pi,S., Chen,W., Kostka,D., Liu,S.,
            Gross,J.M., Kuwajima,T. and Aldiri,I.
  TITLE     A cis-regulatory module underlies retinal ganglion cell genesis and
            axonogenesis
  JOURNAL   Cell Rep 43 (6), 114291 (2024)
   PUBMED   38823017
REFERENCE   4  (bases 1 to 4726)
  AUTHORS   Masuda,A., Nishida,K., Ajima,R., Saga,Y., Bakhtan,M., Klar,A.,
            Hirata,T. and Zhu,Y.
  TITLE     A global gene regulatory program and its region-specific regulator
            partition neurons into commissural and ipsilateral projection types
  JOURNAL   Sci Adv 10 (21), eadk2149 (2024)
   PUBMED   38781326
REFERENCE   5  (bases 1 to 4726)
  AUTHORS   Gradwell,M.A., Ozeri-Engelhard,N., Eisdorfer,J.T., Laflamme,O.D.,
            Gonzalez,M., Upadhyay,A., Medlock,L., Shrier,T., Patel,K.R.,
            Aoki,A., Gandhi,M., Abbas-Zadeh,G., Oputa,O., Thackray,J.K.,
            Ricci,M., George,A., Yusuf,N., Keating,J., Imtiaz,Z., Alomary,S.A.,
            Bohic,M., Haas,M., Hernandez,Y., Prescott,S.A., Akay,T. and
            Abraira,V.E.
  TITLE     Multimodal sensory control of motor performance by glycinergic
            interneurons of the mouse spinal cord deep dorsal horn
  JOURNAL   Neuron 112 (8), 1302-1327 (2024)
   PUBMED   38452762
REFERENCE   6  (bases 1 to 4726)
  AUTHORS   Camurri,L., Mambetisaeva,E. and Sundaresan,V.
  TITLE     Rig-1 a new member of Robo family genes exhibits distinct pattern
            of expression during mouse development
  JOURNAL   Gene Expr Patterns 4 (1), 99-103 (2004)
   PUBMED   14678835
REFERENCE   7  (bases 1 to 4726)
  AUTHORS   Park,K.W., Morrison,C.M., Sorensen,L.K., Jones,C.A., Rao,Y.,
            Chien,C.B., Wu,J.Y., Urness,L.D. and Li,D.Y.
  TITLE     Robo4 is a vascular-specific receptor that inhibits endothelial
            migration
  JOURNAL   Dev Biol 261 (1), 251-267 (2003)
   PUBMED   12941633
REFERENCE   8  (bases 1 to 4726)
  AUTHORS   Yuan,S.S., Yeh,Y.T. and Lee,E.Y.
  TITLE     Pax-2 interacts with RB and reverses its repression on the promoter
            of Rig-1, a Robo member
  JOURNAL   Biochem Biophys Res Commun 296 (4), 1019-1025 (2002)
   PUBMED   12200151
  REMARK    GeneRIF: Pax-2/RB binding reverses repression of Rig-1 protein.
REFERENCE   9  (bases 1 to 4726)
  AUTHORS   Vargesson,N., Luria,V., Messina,I., Erskine,L. and Laufer,E.
  TITLE     Expression patterns of Slit and Robo family members during
            vertebrate limb development
  JOURNAL   Mech Dev 106 (1-2), 175-180 (2001)
   PUBMED   11472852
REFERENCE   10 (bases 1 to 4726)
  AUTHORS   Yuan,S.S., Cox,L.A., Dasika,G.K. and Lee,E.Y.
  TITLE     Cloning and functional studies of a novel gene aberrantly expressed
            in RB-deficient embryos
  JOURNAL   Dev Biol 207 (1), 62-75 (1999)
   PUBMED   10049565
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC138284.9.
            
            On or before Sep 19, 2009 this sequence version replaced
            XM_001478301.1, XM_001476840.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments. The exon-intron structure is
            inferred based on available transcript data and further supported
            by similar exon-intron structure of the orthologous human gene,
            GeneID 64221.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            RNAseq introns :: mixed sample support SAMN00849374, SAMN00849375
                              [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-334               AC138284.9         218603-218936       c
            335-661             AC138284.9         215249-215575       c
            662-819             AC138284.9         214796-214953       c
            820-940             AC138284.9         213751-213871       c
            941-1079            AC138284.9         213516-213654       c
            1080-1207           AC138284.9         213139-213266       c
            1208-1332           AC138284.9         212787-212911       c
            1333-1504           AC138284.9         210968-211139       c
            1505-1710           AC138284.9         210394-210599       c
            1711-1792           AC138284.9         210088-210169       c
            1793-1958           AC138284.9         209651-209816       c
            1959-2125           AC138284.9         208943-209109       c
            2126-2247           AC138284.9         208291-208412       c
            2248-2473           AC138284.9         207876-208101       c
            2474-2595           AC138284.9         207580-207701       c
            2596-2767           AC138284.9         207167-207338       c
            2768-2953           AC138284.9         206649-206834       c
            2954-2977           AC138284.9         205899-205922       c
            2978-3020           AC138284.9         205778-205820       c
            3021-3160           AC138284.9         205430-205569       c
            3161-3355           AC138284.9         204879-205073       c
            3356-3494           AC138284.9         204601-204739       c
            3495-3707           AC138284.9         204247-204459       c
            3708-3859           AC138284.9         203680-203831       c
            3860-3970           AC138284.9         203452-203562       c
            3971-4147           AC138284.9         203087-203263       c
            4148-4371           AC138284.9         202458-202681       c
            4372-4726           AC138284.9         201806-202160       c
FEATURES             Location/Qualifiers
     source          1..4726
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="9"
                     /map="9 20.76 cM"
     gene            1..4726
                     /gene="Robo3"
                     /gene_synonym="Rbig1; Rig-1; Rig1; Robo3a; Robo3b"
                     /note="roundabout guidance receptor 3"
                     /db_xref="GeneID:19649"
                     /db_xref="MGI:MGI:1343102"
     exon            1..334
                     /gene="Robo3"
                     /gene_synonym="Rbig1; Rig-1; Rig1; Robo3a; Robo3b"
                     /inference="alignment:Splign:2.1.0"
     CDS             175..4383
                     /gene="Robo3"
                     /gene_synonym="Rbig1; Rig-1; Rig1; Robo3a; Robo3b"
                     /note="retinoblastoma inhibiting gene 1;
                     retinoblastoma-inhibiting gene 1 protein"
                     /codon_start=1
                     /product="roundabout homolog 3"
                     /protein_id="NP_001158239.1"
                     /db_xref="CCDS:CCDS52770.1"
                     /db_xref="GeneID:19649"
                     /db_xref="MGI:MGI:1343102"
                     /translation="MLRYLLKTLLQMNLFADSLARDISNSSELLFGFNSSLAALNPSL
                     LPPGDPSLNGSRVGPEDAMPRIVEQPPDLVVSRGEPATLPCRAEGRPRPNIEWYKNGA
                     RVATAREDPRAHRLLLPSGALFFPRIVHGRRSRPDEGVYTCVARNYLGAAASRNASLE
                     VAVLRDDFRQSPGNVVVAVGEPAVMECVPPKGHPEPLVTWKKGKIKLKEEEGRITIRG
                     GKLMMSHTFKSDAGMYMCVASNMAGERESGAAELVVLERPSFLRRPINQVVLADAPVN
                     FLCEVQGDPQPNLHWRKDDGELPAGRYEIRSDHSLWIDQVSSEDEGTYTCVAENSVGR
                     AEASGSLSVHVPPQFVTKPQNQTVAPGANVSFQCETKGNPPPAIFWQKEGSQVLLFPS
                     QSLQPMGRLLVSPRGQLNITEVKIGDGGYYVCQAVSVAGSILAKALLEIKGASIDGLP
                     PIILQGPANQTLVLGSSVWLPCRVIGNPQPNIQWKKDERWLQGDDSQFNLMDNGTLHI
                     ASIQEMDMGFYSCVAKSSIGEATWNSWLRKQEDWGASPGPATGPSNPPGPPSQPIVTE
                     VTANSITLTWKPNPQSGATATSYVIEAFSQAAGNTWRTVADGVQLETYTISGLQPNTI
                     YLFLVRAVGAWGLSEPSPVSEPVQTQDSSLSRPAEDPWKGQRGLAEVAVRMQEPTVLG
                     PRTLQVSWTVDGPVQLVQGFRVSWRIAGLDQGSWTMLDLQSPHKQSTVLRGLPPGAQI
                     QIKVQVQGQEGLGAESPFVTRSIPEEAPSGPPQGVAVALGGDRNSSVTVSWEPPLPSQ
                     RNGVITEYQIWCLGNESRFHLNRSAAGWARSVTFSGLLPGQIYRALVAAATSAGVGVA
                     SAPVLVQLPFPPAAEPGPEVSEGLAERLAKVLRKPAFLAGSSAACGALLLGFCAALYR
                     RQKQRKELSHYTASFAYTPAVSFPHSEGLSGSSSRPPMGLGPAAYPWLADSWPHPPRS
                     PSAQEPRGSCCPSNPDPDDRYYNEAGISLYLAQTARGANASGEGPVYSTIDPVGEELQ
                     TFHGGFPQHSSGDPSTWSQYAPPEWSEGDSGARGGQGKLLGKPVQMPSLSWPEALPPP
                     PPSCELSCPEGPEEELKGSSDLEEWCPPVPEKSHLVGSSSSGACMVAPAPRDTPSPTS
                     SYGQQSTATLTPSPPDPPQPPTDIPHLHQMPRRVPLGPSSPLSVSQPALSSHDGRPVG
                     LGAGPVLSYHASPSPVPSTASSAPGRTRQVTGEMTPPLHGHRARIRKKPKALPYRREH
                     SPGDLPPPPLPPPEEETSWPLGLRAAGSMSSLERERSGERRVVQAVPLGAQPLGAQRG
                     PHPDAALLGCAAEEAWLPYGRPSFLSHGQGTSTCSTAGSNSSRGSNSSRGSRGSRGPG
                     RSRSRSRSQSQSQRPGRNRREEPR"
     exon            335..661
                     /gene="Robo3"
                     /gene_synonym="Rbig1; Rig-1; Rig1; Robo3a; Robo3b"
                     /inference="alignment:Splign:2.1.0"
     exon            662..819
                     /gene="Robo3"
                     /gene_synonym="Rbig1; Rig-1; Rig1; Robo3a; Robo3b"
                     /inference="alignment:Splign:2.1.0"
     exon            820..940
                     /gene="Robo3"
                     /gene_synonym="Rbig1; Rig-1; Rig1; Robo3a; Robo3b"
                     /inference="alignment:Splign:2.1.0"
     exon            941..1079
                     /gene="Robo3"
                     /gene_synonym="Rbig1; Rig-1; Rig1; Robo3a; Robo3b"
                     /inference="alignment:Splign:2.1.0"
     exon            1080..1207
                     /gene="Robo3"
                     /gene_synonym="Rbig1; Rig-1; Rig1; Robo3a; Robo3b"
                     /inference="alignment:Splign:2.1.0"
     exon            1208..1332
                     /gene="Robo3"
                     /gene_synonym="Rbig1; Rig-1; Rig1; Robo3a; Robo3b"
                     /inference="alignment:Splign:2.1.0"
     exon            1333..1504
                     /gene="Robo3"
                     /gene_synonym="Rbig1; Rig-1; Rig1; Robo3a; Robo3b"
                     /inference="alignment:Splign:2.1.0"
     exon            1505..1710
                     /gene="Robo3"
                     /gene_synonym="Rbig1; Rig-1; Rig1; Robo3a; Robo3b"
                     /inference="alignment:Splign:2.1.0"
     exon            1711..1792
                     /gene="Robo3"
                     /gene_synonym="Rbig1; Rig-1; Rig1; Robo3a; Robo3b"
                     /inference="alignment:Splign:2.1.0"
     exon            1793..1958
                     /gene="Robo3"
                     /gene_synonym="Rbig1; Rig-1; Rig1; Robo3a; Robo3b"
                     /inference="alignment:Splign:2.1.0"
     exon            1959..2125
                     /gene="Robo3"
                     /gene_synonym="Rbig1; Rig-1; Rig1; Robo3a; Robo3b"
                     /inference="alignment:Splign:2.1.0"
     exon            2126..2247
                     /gene="Robo3"
                     /gene_synonym="Rbig1; Rig-1; Rig1; Robo3a; Robo3b"
                     /inference="alignment:Splign:2.1.0"
     exon            2248..2473
                     /gene="Robo3"
                     /gene_synonym="Rbig1; Rig-1; Rig1; Robo3a; Robo3b"
                     /inference="alignment:Splign:2.1.0"
     exon            2474..2595
                     /gene="Robo3"
                     /gene_synonym="Rbig1; Rig-1; Rig1; Robo3a; Robo3b"
                     /inference="alignment:Splign:2.1.0"
     exon            2596..2767
                     /gene="Robo3"
                     /gene_synonym="Rbig1; Rig-1; Rig1; Robo3a; Robo3b"
                     /inference="alignment:Splign:2.1.0"
     exon            2768..2953
                     /gene="Robo3"
                     /gene_synonym="Rbig1; Rig-1; Rig1; Robo3a; Robo3b"
                     /inference="alignment:Splign:2.1.0"
     exon            2954..2977
                     /gene="Robo3"
                     /gene_synonym="Rbig1; Rig-1; Rig1; Robo3a; Robo3b"
                     /inference="alignment:Splign:2.1.0"
     exon            2978..3020
                     /gene="Robo3"
                     /gene_synonym="Rbig1; Rig-1; Rig1; Robo3a; Robo3b"
                     /inference="alignment:Splign:2.1.0"
     exon            3021..3160
                     /gene="Robo3"
                     /gene_synonym="Rbig1; Rig-1; Rig1; Robo3a; Robo3b"
                     /inference="alignment:Splign:2.1.0"
     exon            3161..3355
                     /gene="Robo3"
                     /gene_synonym="Rbig1; Rig-1; Rig1; Robo3a; Robo3b"
                     /inference="alignment:Splign:2.1.0"
     exon            3356..3494
                     /gene="Robo3"
                     /gene_synonym="Rbig1; Rig-1; Rig1; Robo3a; Robo3b"
                     /inference="alignment:Splign:2.1.0"
     exon            3495..3707
                     /gene="Robo3"
                     /gene_synonym="Rbig1; Rig-1; Rig1; Robo3a; Robo3b"
                     /inference="alignment:Splign:2.1.0"
     exon            3708..3859
                     /gene="Robo3"
                     /gene_synonym="Rbig1; Rig-1; Rig1; Robo3a; Robo3b"
                     /inference="alignment:Splign:2.1.0"
     exon            3860..3970
                     /gene="Robo3"
                     /gene_synonym="Rbig1; Rig-1; Rig1; Robo3a; Robo3b"
                     /inference="alignment:Splign:2.1.0"
     exon            3971..4147
                     /gene="Robo3"
                     /gene_synonym="Rbig1; Rig-1; Rig1; Robo3a; Robo3b"
                     /inference="alignment:Splign:2.1.0"
     exon            4148..4371
                     /gene="Robo3"
                     /gene_synonym="Rbig1; Rig-1; Rig1; Robo3a; Robo3b"
                     /inference="alignment:Splign:2.1.0"
     exon            4372..4726
                     /gene="Robo3"
                     /gene_synonym="Rbig1; Rig-1; Rig1; Robo3a; Robo3b"
                     /inference="alignment:Splign:2.1.0"
     regulatory      4621..4626
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Robo3"
                     /gene_synonym="Rbig1; Rig-1; Rig1; Robo3a; Robo3b"
                     /note="hexamer: AAGAAA"
     polyA_site      4642
                     /gene="Robo3"
                     /gene_synonym="Rbig1; Rig-1; Rig1; Robo3a; Robo3b"
                     /note="major polyA site"
ORIGIN      
        1 gaggacagcc cgcgcagagg cacggccggt acccaggcac gcctgcagga cagcggcatc
       61 gtggctgccg cagcgcgcaa aggctgtgga ggggcttacg gctcccggcc cgcgggtccc
      121 agacccaagg gctgggctcc gaggcccctg cccaagaccc aggcgggctg cgctatgctg
      181 cgctacctgc ttaaaacact actacagatg aacttgttcg cggactccct ggccagggac
      241 atctccaact ccagcgagct actcttcggc ttcaactcct cgctggcagc gctcaaccct
      301 agtctgcttc ctcctggaga tccctctctc aatgggtcaa gagttgggcc agaagatgcc
      361 atgccacgca tcgtggagca gccgccagat ctggtggttt ccaggggcga gccggctact
      421 ctgccctgtc gtgcagaagg ccggcctcga cccaacatcg agtggtacaa gaatggggcg
      481 cgtgtggcga ctgcacggga ggatccgcgt gctcaccgtc tgctgctgcc cagcggcgcc
      541 ctcttctttc cccgcattgt gcacgggcgt cgctctcggc ctgacgaggg tgtctacacc
      601 tgtgtggctc gcaactacct gggagcagcg gctagcagaa acgcctctct ggaagtagct
      661 gtcctccgtg atgatttccg gcaatcgcct gggaacgtgg tggtagcggt gggggagcca
      721 gctgtaatgg aatgtgtgcc ccctaagggt cacccagagc ctttggtgac ctggaagaaa
      781 ggcaaaataa agcttaagga agaggaggga aggatcacca tacgtggagg aaagctgatg
      841 atgtcacaca cgttcaagag tgatgctggc atgtatatgt gcgtagcctc caacatggct
      901 ggagaacgag agagtggggc agctgaactt gtggtactgg agcgtccctc atttctgcgt
      961 agaccaataa accaggttgt cctggctgat gcccctgtga atttcctgtg tgaggtgcag
     1021 ggagatcccc agcccaatct acactggcgc aaggatgatg gggagctgcc cgcgggcagg
     1081 tatgagattc ggagtgacca cagcctttgg atcgaccaag tgagctctga agacgagggg
     1141 acgtacacgt gtgtagcaga gaacagtgtg ggccgcgcag aggcatctgg ctccctcagt
     1201 gttcacgtcc caccacaatt tgtgactaag ccccagaacc agacagtagc tcccggagca
     1261 aacgtgtcat tccaatgtga gaccaaagga aaccctccac ctgccatctt ctggcagaag
     1321 gaagggagtc aagtcctgct tttccctagt cagtcactcc aacccatggg acgcctctta
     1381 gtctctccaa gaggccagct caacatcact gaagtaaaga tcggggatgg tggctactac
     1441 gtgtgccagg ctgtcagtgt ggctggtagc atcctagcaa aggccctatt agagataaaa
     1501 ggcgcctcca tagatgggct acctcccatc attctccagg gaccagccaa tcagacactg
     1561 gtacttggct cttctgtgtg gctgccatgc agagtgattg gaaaccccca gcccaacatc
     1621 cagtggaaga aggatgagag gtggctgcag ggggatgact cacagttcaa cttaatggac
     1681 aatggcactc tacacattgc cagcatacag gagatggaca tgggtttcta cagctgtgtg
     1741 gccaagagtt ccatagggga ggccacatgg aatagctggc ttaggaagca agaagattgg
     1801 ggagcatcac caggtccagc aacaggaccc agtaatcctc cagggcctcc ctctcagcca
     1861 atagtcacag aggtaaccgc aaacagcatt accttgacct ggaagcccaa tccacagtct
     1921 ggggccacag ctacctccta tgtgatagag gccttcagcc aagcagctgg caacacgtgg
     1981 cggacggtgg ccgatggggt gcagctggaa acttacacca tcagtggcct gcagcccaac
     2041 accatctact tattcctagt gagagcagtt ggagcctggg gcctcagtga acccagtcct
     2101 gtctctgagc ctgttcaaac ccaggacagc agcctatcta ggccagcgga ggacccgtgg
     2161 aaaggccagc gagggctagc ggaagtggcc gtgcgaatgc aggagcccac tgtccttggg
     2221 cccagaactc tgcaggtttc ctggactgtg gatggtccag tccagctggt gcaaggattc
     2281 cgtgtgtctt ggaggattgc aggccttgac cagggaagct ggacaatgct agacctacag
     2341 agtccacaca agcaaagtac tgtgctaaga ggactgcccc caggggccca aatccagatc
     2401 aaggtgcaag tccaaggcca ggaggggctg ggggctgaaa gcccttttgt gaccaggagc
     2461 attcctgagg aggcccccag tggcccccct cagggagtgg ctgtggcctt ggggggtgat
     2521 cgcaacagca gtgtcactgt atcctgggag cctccacttc cctcccagcg aaatggggtc
     2581 atcactgaat accagatttg gtgcctgggt aatgaaagcc gattccacct caatcgatct
     2641 gcagcaggtt gggcacgctc tgtgacgttc agcggactgc taccaggcca gatctatcga
     2701 gccttggtgg cagcagctac cagtgctggc gtgggcgtgg ccagtgctcc agtgctagtg
     2761 cagctgccat tccctccggc ggcggagccg gggcctgagg tcagcgaggg gctggcagaa
     2821 cggttggcta aggtgctgcg gaagcctgct ttcctagctg gcagcagcgc agcctgcggg
     2881 gcgctgctac tcgggttctg cgccgccctc taccggcgtc agaagcagcg caaagaactc
     2941 agtcactata cggcctcctt tgcctacaca cctgcagtgt cctttccaca ctcagagggc
     3001 ctttctggat ccagttccag gccacccatg ggccttggcc ctgctgccta cccatggctg
     3061 gcagactcct ggccccaccc acctcggagt ccctcagctc aggagccccg ggggagctgc
     3121 tgccccagca atcctgatcc agatgataga tactacaatg aggcaggaat ctccctgtac
     3181 ttggctcaga ctgcacgtgg tgctaatgcc tctggtgagg gtcctgtcta cagcaccatt
     3241 gacccagtag gggaagagct acagaccttc cacggagggt tccctcaaca ctcttctggg
     3301 gacccaagca cctggagcca gtatgctccc ccggaatgga gcgaggggga cagtggagcc
     3361 aggggaggcc aggggaagct tctgggcaag cctgtacaaa tgccatcttt gagctggcca
     3421 gaagccctgc caccgcctcc cccttcctgt gagctgagct gtccggaggg gcctgaggag
     3481 gagctgaagg gcagttcaga tctggaagag tggtgcccac cagtgcctga gaaaagccac
     3541 ttggttgggt caagctccag tggtgcgtgc atggtggctc cagccccaag ggacacaccc
     3601 tcccccactt cttcttatgg acagcagtcc acagctactc ttaccccctc acctcctgat
     3661 cctccccaac cccctactga catcccacat ctccatcaga tgcccaggag agtacccctc
     3721 gggccaagtt ctcctctcag cgtatcccag cccgctctga gtagccatga cggacggcct
     3781 gttggcctgg gtgctggccc cgtactctcc tatcacgcta gccccagtcc tgtccctagt
     3841 acagccagca gtgcaccggg gagaacccgt caggtaactg gagagatgac tcccccactc
     3901 catggacacc gtgctcgaat ccggaagaaa cccaaggctc ttccctacag aagggagcac
     3961 agtcccgggg acttgccccc accacccttg ccaccaccag aggaagagac aagctggccc
     4021 ttgggtctgc gggcagcagg cagcatgtct tccctagagc gagagcgcag tggggagagg
     4081 agagtggtgc aggcagtgcc tctaggggcc caacctctag gggcccaacg tgggccccac
     4141 ccagatgctg cacttctggg ttgtgctgcg gaagaggcct ggcttccata cggcagacca
     4201 agcttcctga gccatggcca gggcaccagc acctgctcta ccgctggtag caattcttct
     4261 aggggttcca acagctctcg aggttctcgg ggctctcggg gccctggacg cagccgaagt
     4321 cgaagccgga gccagagcca gagccagagg ccaggacgga atcgccgaga ggaaccaaga
     4381 tgacccttca cgaagcaatg agcttattga aggctccaca gtgcaagaat atgaacccct
     4441 tccctggtca accgatgtgg gccaagagga gcaaggatgg gcagactttc ctcccagcaa
     4501 tgatgcttgt gactcactga agcacactgt ctacaacagt tttagttgtc ttgggaatca
     4561 gagaactagc tctttacttt ccatctcgtt ctgactgaga catgtttgta caaaaggaga
     4621 aagaaaaaag cctccgatct gagccctggt ccctgcttgt tttgtgcagt gttgtaagta
     4681 gagcaggcta tgaaggtctg aaggtcaata cacgctggta gcttct
//
