LOCUS       NM_001146026            3933 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus ring finger protein 44 (Rnf44), transcript variant 2,
            mRNA.
ACCESSION   NM_001146026
VERSION     NM_001146026.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3933)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 3933)
  AUTHORS   Wiese,C.B., Ireland,S., Fleming,N.L., Yu,J., Valerius,M.T.,
            Georgas,K., Chiu,H.S., Brennan,J., Armstrong,J., Little,M.H.,
            McMahon,A.P. and Southard-Smith,E.M.
  TITLE     A genome-wide screen to identify transcription factors expressed in
            pelvic Ganglia of the lower urinary tract
  JOURNAL   Front Neurosci 6, 130 (2012)
   PUBMED   22988430
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 3933)
  AUTHORS   Okazaki,N., Kikuno,R., Ohara,R., Inamoto,S., Koseki,H., Hiraoka,S.,
            Saga,Y., Nagase,T., Ohara,O. and Koga,H.
  TITLE     Prediction of the coding sequences of mouse homologues of KIAA
            gene: III. the complete nucleotide sequences of 500 mouse
            KIAA-homologous cDNAs identified by screening of terminal sequences
            of cDNA clones randomly sampled from size-fractionated libraries
  JOURNAL   DNA Res 10 (4), 167-180 (2003)
   PUBMED   14621295
REFERENCE   4  (bases 1 to 3933)
  AUTHORS   Stryke,D., Kawamoto,M., Huang,C.C., Johns,S.J., King,L.A.,
            Harper,C.A., Meng,E.C., Lee,R.E., Yee,A., L'Italien,L.,
            Chuang,P.T., Young,S.G., Skarnes,W.C., Babbitt,P.C. and Ferrin,T.E.
  TITLE     BayGenomics: a resource of insertional mutations in mouse embryonic
            stem cells
  JOURNAL   Nucleic Acids Res 31 (1), 278-281 (2003)
   PUBMED   12520002
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            CJ106658.1, AK147349.1, BC017630.1 and CF426263.1.
            
            Transcript Variant: This variant (2) uses an alternate in-frame
            splice site in the 5' coding region, compared to variant 1,
            resulting in an isoform (2) that is shorter than isoform 1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK147349.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164139 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-5                 CJ106658.1         2-6
            6-2410              AK147349.1         7-2411
            2411-3920           BC017630.1         2212-3721
            3921-3933           CF426263.1         529-541
FEATURES             Location/Qualifiers
     source          1..3933
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="13"
                     /map="13 28.94 cM"
     gene            1..3933
                     /gene="Rnf44"
                     /gene_synonym="mKIAA1100"
                     /note="ring finger protein 44"
                     /db_xref="GeneID:105239"
                     /db_xref="MGI:MGI:2145310"
     exon            1..315
                     /gene="Rnf44"
                     /gene_synonym="mKIAA1100"
                     /inference="alignment:Splign:2.1.0"
     exon            316..466
                     /gene="Rnf44"
                     /gene_synonym="mKIAA1100"
                     /inference="alignment:Splign:2.1.0"
     CDS             360..1583
                     /gene="Rnf44"
                     /gene_synonym="mKIAA1100"
                     /note="isoform 2 is encoded by transcript variant 2"
                     /codon_start=1
                     /product="RING finger protein 44 isoform 2"
                     /protein_id="NP_001139498.1"
                     /db_xref="GeneID:105239"
                     /db_xref="MGI:MGI:2145310"
                     /translation="MRPWTLAVTKWPPSAPVGHWRVSTRLSSSPGQLWGRPSNLSVEE
                     HRASAPAGRSPRMLHPATQQSPFMVDLHEQVHQGPVPLSYTVTTVTTQGFPLPTSQHI
                     PGCSAQQLPACSVMFSGQHYPLCCLPPPQLIQACTMQQLPGPYHTYPHLISSDHYILH
                     PPPPAPPPQPTHMAPLGQFVSLQTQHPRMPLQRLDNEMDLRGDQHPLGSFTYSTSATG
                     PALSPSVPLHYLPHDPLHQELSFGVPYSHMMPRRLSTQRYRLQQPLPPPPPPPPPSYY
                     PSFLPYFLSMLPMSPTTVGPTISLDLDVDDVEMENYEALLNLAERLGDAKPRGLTKAD
                     IEQLPSYRFNPDSHQSEQTLCVVCFSDFEVRQLLRVLPCNHEFHAKCVDKWLKANRTC
                     PICRADASEVPREAE"
     exon            467..581
                     /gene="Rnf44"
                     /gene_synonym="mKIAA1100"
                     /inference="alignment:Splign:2.1.0"
     exon            582..749
                     /gene="Rnf44"
                     /gene_synonym="mKIAA1100"
                     /inference="alignment:Splign:2.1.0"
     exon            750..926
                     /gene="Rnf44"
                     /gene_synonym="mKIAA1100"
                     /inference="alignment:Splign:2.1.0"
     exon            927..1088
                     /gene="Rnf44"
                     /gene_synonym="mKIAA1100"
                     /inference="alignment:Splign:2.1.0"
     exon            1089..1210
                     /gene="Rnf44"
                     /gene_synonym="mKIAA1100"
                     /inference="alignment:Splign:2.1.0"
     exon            1211..1298
                     /gene="Rnf44"
                     /gene_synonym="mKIAA1100"
                     /inference="alignment:Splign:2.1.0"
     exon            1299..1420
                     /gene="Rnf44"
                     /gene_synonym="mKIAA1100"
                     /inference="alignment:Splign:2.1.0"
     exon            1421..1520
                     /gene="Rnf44"
                     /gene_synonym="mKIAA1100"
                     /inference="alignment:Splign:2.1.0"
     exon            1521..3933
                     /gene="Rnf44"
                     /gene_synonym="mKIAA1100"
                     /inference="alignment:Splign:2.1.0"
     regulatory      3901..3906
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Rnf44"
                     /gene_synonym="mKIAA1100"
                     /note="hexamer: AATAAA"
     polyA_site      3933
                     /gene="Rnf44"
                     /gene_synonym="mKIAA1100"
                     /note="major polyA site"
ORIGIN      
        1 ggggcgggtg tccgctcttg ccgctactgt ttgcttgcgc gtcctggcgc gcccccgcga
       61 gccgcctccc gcgctgcgcg cccccgccga tccgaatgtt gtgaatcaaa acgtggggct
      121 ggttccatcc ggccgccgcg gacagttctt aaagggccag cccgccggag agcacagctg
      181 cgtcctgcgc cgcccttctc tcgggcccgg gctggggagg cggaagacag agcaggctcg
      241 cgaaggagcg ggcgcttcac cgtccgcacc ccgcatcgcg aacaaaggag cccgcgtgtg
      301 gtcggacggc tgccgggttg tgagccccgg cacagcccct ccacctccct gccctcctga
      361 tgagaccatg gactttggca gtgactaagt ggccaccttc tgcccctgtg ggtcactggc
      421 gagtctctac aaggcttagc agcagtccag gccagctctg gggaagacca tcaaacctct
      481 ctgtagagga gcaccgagcc tcagctcctg ccggcaggag cccccgaatg ctgcacccag
      541 ccacccagca gagcccgttc atggttgatc tccacgaaca agtgcaccag ggacctgtcc
      601 ctctgtccta cacggtcacc acagtgacaa cccaaggctt ccctttgcct acaagccaac
      661 acatccctgg ctgcagtgcc cagcagctcc cagcatgctc cgtgatgttc agtgggcagc
      721 actaccccct ctgctgcctc ccacctccgc agctgatcca ggcgtgcacc atgcagcagc
      781 tccctgggcc ctaccacacc tacccccacc tcatctccag tgaccactac atccttcacc
      841 caccaccgcc agccccaccg ccccagccta cccacatggc accgcttggg cagtttgtgt
      901 ccctgcagac ccagcaccca cgtatgcccc tgcagcggct ggataacgag atggaccttc
      961 gaggagacca gcaccccttg ggtagcttca cttactccac ctctgccact ggcccagcct
     1021 tgtcgccctc agtgcccctt cactacctac cccatgatcc actgcaccag gagctgtcct
     1081 ttggtgtgcc atattcccac atgatgccac gaagactgag cacacagaga taccgcctgc
     1141 aacagccgct gccaccaccc ccaccgccgc cgccaccatc ttactaccca agcttcctac
     1201 cctacttcct ttcaatgctg ccaatgtcac cgaccaccgt gggccccacc atcagcttgg
     1261 acctggacgt ggatgacgta gagatggaga actatgaggc tctcctgaac ctggctgagc
     1321 ggctgggaga cgccaagccc cggggcctca ccaaagcaga catcgaacaa ctgccgtcgt
     1381 atcgctttaa ccctgacagc catcagtctg agcagactct gtgtgtggtc tgcttcagtg
     1441 acttcgaggt gcggcaactg ctccgagtcc tcccctgcaa ccacgagttc catgccaagt
     1501 gtgttgacaa gtggttgaag gccaaccgga cctgtcccat ttgccgggcg gatgcctccg
     1561 aggtgcccag ggaggccgag tgaggctcca cagccaccca cgagatccct gcccaaagct
     1621 ccggaattgg gtggggggga gcagggcgtg gcccggggag gactgtgagg gcggggccag
     1681 gcctgtcagc gttcccacct gccactccag agctggtgcc agggtcagtc tggagaagcc
     1741 cctgcaataa gcccctgcat tgccaagctc caaagactcc ttccccagtc tgcctgcctg
     1801 cctgcctgcc cgccacggag ctgcctgagt ttccccaact cagtctgctt cttatctgcc
     1861 cctgggtcct tcttcctgct ggctctggga ggcaggagtc cattccccaa gtgtggtggc
     1921 tggtgtgatt tccccagacc ccagacggac aaaggaatag ccaccctggg tcaactggtc
     1981 tcctgtactg aaatgacgtg tccttccctg ccctagtggg gttgccaggt gtgtgggcag
     2041 ggagtagcca gagaccattt cctgagttct cctgtttggt tccagacaga cataggcagt
     2101 cagctctgcc tccactgctg tgtggtgtgg gtctgactcc ccaggaccct taccccaggc
     2161 acagcgttcc agcccacccc caggctggag agtatcccag ccaggctcca tgagcaaatg
     2221 ggccagggct ccaagctgga tacattgtgt tctgcagtag cctcgagcga tctgggcatg
     2281 ttcttgtgtt cctggtggct gcccctccac cagtgacagt gtcagaccca tgctcgatcc
     2341 tccccctctg tctttttgca tgaatgtgag gaacagcagt ttttgtttat tcatttggcc
     2401 caaaattgcg tgtagggggt gtggatattt aagaggtgtt tagtttttta ttatcttgtt
     2461 ttctctttgg tttaatagga gtgggggcat agggaccaac cgggaccaaa tgcccagggg
     2521 gcagagtagg gtccggttct gccacaccag gcctccacat gagtgtgtgc ggctggaact
     2581 ttatctgggt ggctggaagt cacagggcgg agtttggggg ggtctgtgct cagctgataa
     2641 ctgccatgca ctgtactgca catgtcccta gagcctaccg ggaccgtctg cttttcaggg
     2701 catctcctct ccagccaggg cctgtgtccc acctgcctgg gtgagtctcc tagcaatcct
     2761 gtgaggacag gggtcaggga ggacatgaac ctccacctca gggggcccct cccggcctga
     2821 ttcctgccct ccaaggtctg gaggaggctg tgttccttac cctcctttca ggtcccactc
     2881 ctttcctttc ctaccgccaa ctggggttgc tgcgctgcct ggagtgaacg aaccgcgtgt
     2941 ggggccggca catcctagca ggcagccatt ggcgcctgct gcctcaggga tgctccaacc
     3001 accctcgttc tcaccgcagc cctgccccca ccccagcctg ccaggcccca ttggcctggt
     3061 cccaccccac aagaacccaa agtcttactg tatataactc caggtgatgt ttctatattt
     3121 atagcagtgt tgaaaatcca cgtgttttac acagagaacc accttctcca acccccatcc
     3181 cttcctcacc ccaaaaaagg ttttcaaacc cttgtggttc ctggggcagc agaattggct
     3241 catggactgt gtcggctgca gtgatgattc cagcaagcag ctactagggg gaaatacacc
     3301 ttttttgttt gtttgttttt aatcatttaa aaaagattta tgaaacaatt acttaggatg
     3361 tttgtgattt gccgaccttg ctgtagatgc catgttacca atgatttcct gtggtggggg
     3421 cttggcattg tttactcttt atttaccaac ttctggccta ggcatgacag tgggcacctt
     3481 cccccagcac tgctgggccc agcgcctgtg ttctgtgtta gaaaagtttt atatatatat
     3541 atctaactaa acacacacac acatatatat atatatataa acacatgtga tttgggggcc
     3601 ctgttccttg cacatcttac agttacctca tttttcccat gtatgtattt gagaaaatgc
     3661 taatatatag agacaaatgg ttcttaaagc ttaaatgtgt ggttttttcc atcccattgg
     3721 actcacattg gtttgtagca tttaacataa ctagtatgtt gtattatata tgtgtatact
     3781 gattgaaatt tttaacagat ttgtactttt tttaaaatga aagttgctag ttctgcttga
     3841 ccaagtagtg caatcattat tttttttaat attgttgctg atttcagagg gatattcact
     3901 aataaatgta tgatgtatac gagtgctgcc caa
//
