LOCUS       NM_022423               1971 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus ring finger protein 187 (Rnf187), mRNA.
ACCESSION   NM_022423 XM_905766 XM_992215
VERSION     NM_022423.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1971)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 1971)
  AUTHORS   Yu,X., Xu,B., Gao,T., Fu,X., Jiang,B., Zhou,N., Gao,W., Wu,T.,
            Shen,C., Huang,X., Wu,Y. and Zheng,B.
  TITLE     E3 ubiquitin ligase RNF187 promotes growth of spermatogonia via
            lysine 48-linked polyubiquitination-mediated degradation of
            KRT36/KRT84
  JOURNAL   FASEB J 37 (10), e23217 (2023)
   PUBMED   37738023
  REMARK    GeneRIF: E3 ubiquitin ligase RNF187 promotes growth of
            spermatogonia via lysine 48-linked polyubiquitination-mediated
            degradation of KRT36/KRT84.
REFERENCE   3  (bases 1 to 1971)
  AUTHORS   Wiese,C.B., Ireland,S., Fleming,N.L., Yu,J., Valerius,M.T.,
            Georgas,K., Chiu,H.S., Brennan,J., Armstrong,J., Little,M.H.,
            McMahon,A.P. and Southard-Smith,E.M.
  TITLE     A genome-wide screen to identify transcription factors expressed in
            pelvic Ganglia of the lower urinary tract
  JOURNAL   Front Neurosci 6, 130 (2012)
   PUBMED   22988430
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 1971)
  AUTHORS   Abler,L.L., Keil,K.P., Mehta,V., Joshi,P.S., Schmitz,C.T. and
            Vezina,C.M.
  TITLE     A high-resolution molecular atlas of the fetal mouse lower
            urogenital tract
  JOURNAL   Dev Dyn 240 (10), 2364-2377 (2011)
   PUBMED   21905163
REFERENCE   5  (bases 1 to 1971)
  AUTHORS   Davies,C.C., Chakraborty,A., Cipriani,F., Haigh,K., Haigh,J.J. and
            Behrens,A.
  TITLE     Identification of a co-activator that links growth factor
            signalling to c-Jun/AP-1 activation
  JOURNAL   Nat Cell Biol 12 (10), 963-972 (2010)
   PUBMED   20852630
REFERENCE   6  (bases 1 to 1971)
  AUTHORS   Blackshaw,S., Harpavat,S., Trimarchi,J., Cai,L., Huang,H.,
            Kuo,W.P., Weber,G., Lee,K., Fraioli,R.E., Cho,S.H., Yung,R.,
            Asch,E., Ohno-Machado,L., Wong,W.H. and Cepko,C.L.
  TITLE     Genomic analysis of mouse retinal development
  JOURNAL   PLoS Biol 2 (9), E247 (2004)
   PUBMED   15226823
REFERENCE   7  (bases 1 to 1971)
  AUTHORS   Inoue,S., Sano,H. and Ohta,M.
  TITLE     Growth suppression of Escherichia coli by induction of expression
            of mammalian genes with transmembrane or ATPase domains
  JOURNAL   Biochem Biophys Res Commun 268 (2), 553-561 (2000)
   PUBMED   10679242
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            CJ180431.1 and BC072613.1.
            
            [WARNING] On Jan 13, 2025 this sequence was replaced by
            NM_022423.3.
            
            On or before Aug 21, 2009 this sequence version replaced
            XM_992215.2, XM_905766.2, NM_022423.1.
            
            Sequence Note: The annotated protein is predicted to be translated
            from a non-AUG start codon based on cross-species sequence
            conservation, and includes a RING domain that would not be present
            if translation were to initiate from the first in-frame AUG.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC072613.1, AK088973.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849380
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            non-AUG initiation codon :: inferred from conservation
            RefSeq Select criteria   :: based on single protein-coding
                                        transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-7                 CJ180431.1         2-8
            8-1971              BC072613.1         1-1964
FEATURES             Location/Qualifiers
     source          1..1971
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="11"
                     /map="11 36.37 cM"
     gene            1..1971
                     /gene="Rnf187"
                     /gene_synonym="2410016F01Rik; RACO-1"
                     /note="ring finger protein 187"
                     /db_xref="GeneID:108660"
                     /db_xref="MGI:MGI:1914224"
     exon            1..512
                     /gene="Rnf187"
                     /gene_synonym="2410016F01Rik; RACO-1"
                     /inference="alignment:Splign:2.1.0"
     exon            513..605
                     /gene="Rnf187"
                     /gene_synonym="2410016F01Rik; RACO-1"
                     /inference="alignment:Splign:2.1.0"
     exon            606..830
                     /gene="Rnf187"
                     /gene_synonym="2410016F01Rik; RACO-1"
                     /inference="alignment:Splign:2.1.0"
     exon            831..1939
                     /gene="Rnf187"
                     /gene_synonym="2410016F01Rik; RACO-1"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1918..1923
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Rnf187"
                     /gene_synonym="2410016F01Rik; RACO-1"
                     /note="hexamer: AATAAA"
     polyA_site      1936
                     /gene="Rnf187"
                     /gene_synonym="2410016F01Rik; RACO-1"
                     /note="major polyA site"
ORIGIN      
        1 ggcgttggcg cagtctgggt ctgagtcgta ggctgaggct cgtcggcctt gatctccggc
       61 cggtcctcgg cccttctgcg ccctctccgc ccgcgccctc gtcggcgccg ccgcccgcag
      121 ccctggcgct ccccgcgggc ccagctgatg ccatctgcgc cctgtgtcag cgcgcgcccc
      181 gcgaaccggt gcgcgccgac tgcggccacc gtttctgccg ggcgtgcgtg gtgcgcttct
      241 gggccgagga ggacgggccc ttcccgtgcc cggagtgtgc cgatgactgc tggcagcgcg
      301 ccgtagagcc cagccgccct ccgctcagcc gccgcctcct ggctctcgag gaggcggccg
      361 cggcgccggc gcgcgatggc cctgccagcg aggccgcgct gcagctgctc tgtcgcgccg
      421 acggggatcc gctgtgctcc gcctgccgca tggccgctgg cccggagccg ccggagtggg
      481 aaccgcgctg gaggaaggcc ctgcgcggca aggagaacaa gggctctgtg gaaatcatga
      541 ggaaggactt aaatgatgcc cgggacctgc atggtcaggc agaatcagcg gctgctgtgt
      601 ggaaggggca tgttatggac cgaaggaaga aggccctgac tgactataag aagcttcggg
      661 ccttcttcgt ggaggaggag gaacactttc tgcaagaggc tgagaaggat gagggtgctt
      721 ccgaggatga tgagctggcc gacccggcag atcgcttccg gtccctgctg caggctgtgt
      781 cagagctgga gaagaagcac cgcaacctgg gcctcagcat gcttctgcag tgatgatgct
      841 ggcccagcag gctggccccc tggagcacga ggcagaagga accaccttct acagctggcc
      901 tgcagcaccc ctacctacat ccctcaggcc tctgcctggc accacccttc atcctggaca
      961 gatccccatc tccatcaaca cttgacagcc tgggatgaag catcagaggt gccccgctgg
     1021 ccatgcacat agttccattg ttcagcagtg tttttcattt tctttggggc atgaatgtgc
     1081 tcgggcttgt acctgttcca aatagagacc taccagtcct gggattcctt tcccagtgtg
     1141 tgccagccct gcctgggacc acttggcagc tcggaagccc ctgcttcttg ttttgccatg
     1201 gctcagctta gtgtggcatt cgttctagta tccaggaacc aagcctcaca cctttcccat
     1261 tggtgcccgt gacagggttg gctcactaga catccctcag caaggttctg aggcgcacca
     1321 gttacagtca gcctgtgtgt gttagtgcca gagaataggg atgcaggagg tcctggggtt
     1381 tggctgggac ctgagtgtta atgcagtatt cctcacccac cagaggacct ctttcctcac
     1441 tttgggtctc actgtgccag gtcctgggag ccgccttctg cttcgcttcc cagcctctct
     1501 tcctcccagc ttgtgcccct ttgggtgtcg ctggcatccc caaagtgatt tctcctcctt
     1561 cccacctctg atggaaggga cctccttccc tgcagaagag cagcagggtg gcatccccag
     1621 gccgccgggt gcttcacttc gctgtagttt tggcttttgc tcacctcata ttttctccaa
     1681 taggtgaatt tcacaaaact tgtgacgtag cggtagtgtg gttgcctgca gcatcgtgtg
     1741 tgtagataac tagtccaaga aacaaaaccc ggcagagtgg acagacacag gtcaggggcc
     1801 aaagacatag atgtatttag gtttcgggta acaatgttct gtccccagaa ggccccagcc
     1861 ttggatgtag tgaccggcct caacttgact cgcaggtggg ctgggttttc agtgctgaat
     1921 aaagtggttt gctccagcca aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa a
//
