LOCUS       NM_001033043            5148 bp    mRNA    linear   ROD 02-JUN-2024
DEFINITION  Mus musculus ring finger protein 17 (Rnf17), mRNA.
ACCESSION   NM_001033043 NM_013894 XM_619253
VERSION     NM_001033043.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 5148)
  AUTHORS   Chukrallah,L.G., Potgieter,S., Chueh,L. and Snyder,E.M.
  TITLE     Two RNA binding proteins, ADAD2 and RNF17, interact to form a
            heterogeneous population of novel meiotic germ cell granules with
            developmentally dependent organelle association
  JOURNAL   PLoS Genet 19 (7), e1010519 (2023)
   PUBMED   37428816
  REMARK    GeneRIF: Two RNA binding proteins, ADAD2 and RNF17, interact to
            form a heterogeneous population of novel meiotic germ cell granules
            with developmentally dependent organelle association.
            Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5148)
  AUTHORS   Xiong,M., Yin,L., Gui,Y., Lv,C., Ma,X., Guo,S., Wu,Y., Feng,S.,
            Fan,X., Zhou,S., Wang,L., Wen,Y., Wang,X., Xie,Q., Namekawa,S.H.
            and Yuan,S.
  TITLE     ADAD2 interacts with RNF17 in P-bodies to repress the Ping-pong
            cycle in pachytene piRNA biogenesis
  JOURNAL   J Cell Biol 222 (5) (2023)
   PUBMED   36930220
REFERENCE   3  (bases 1 to 5148)
  AUTHORS   Wasik,K.A., Tam,O.H., Knott,S.R., Falciatori,I., Hammell,M.,
            Vagin,V.V. and Hannon,G.J.
  TITLE     RNF17 blocks promiscuous activity of PIWI proteins in mouse testes
  JOURNAL   Genes Dev 29 (13), 1403-1415 (2015)
   PUBMED   26115953
  REMARK    GeneRIF: RNF17 shapes adult meiotic piRNA content by suppressing
            the production of secondary piRNAs
REFERENCE   4  (bases 1 to 5148)
  AUTHORS   Vasileva,A., Tiedau,D., Firooznia,A., Muller-Reichert,T. and
            Jessberger,R.
  TITLE     Tdrd6 is required for spermiogenesis, chromatoid body architecture,
            and regulation of miRNA expression
  JOURNAL   Curr Biol 19 (8), 630-639 (2009)
   PUBMED   19345099
REFERENCE   5  (bases 1 to 5148)
  AUTHORS   Pan,J., Goodheart,M., Chuma,S., Nakatsuji,N., Page,D.C. and
            Wang,P.J.
  TITLE     RNF17, a component of the mammalian germ cell nuage, is essential
            for spermiogenesis
  JOURNAL   Development 132 (18), 4029-4039 (2005)
   PUBMED   16093322
  REMARK    GeneRIF: RNF17 is a component of a novel germ cell nuage and is
            required for differentiation of male germ cells.
            GeneRIF: RNF17 is required for spermiogenesis in mouse. There are
            two RNF17 protein isoforms: RNF17L and RNF17S. RNF17 localizes to a
            novel nuage in germ cells.
REFERENCE   6  (bases 1 to 5148)
  AUTHORS   Cobellis,G., Nicolaus,G., Iovino,M., Romito,A., Marra,E.,
            Barbarisi,M., Sardiello,M., Di Giorgio,F.P., Iovino,N., Zollo,M.,
            Ballabio,A. and Cortese,R.
  TITLE     Tagging genes with cassette-exchange sites
  JOURNAL   Nucleic Acids Res 33 (4), e44 (2005)
   PUBMED   15741177
  REMARK    Publication Status: Online-Only
REFERENCE   7  (bases 1 to 5148)
  AUTHORS   Wang,P.J., McCarrey,J.R., Yang,F. and Page,D.C.
  TITLE     An abundance of X-linked genes expressed in spermatogonia
  JOURNAL   Nat Genet 27 (4), 422-426 (2001)
   PUBMED   11279525
REFERENCE   8  (bases 1 to 5148)
  AUTHORS   Yin,X.Y., Gupta,K., Han,W.P., Levitan,E.S. and Prochownik,E.V.
  TITLE     Mmip-2, a novel RING finger protein that interacts with mad members
            of the Myc oncoprotein network
  JOURNAL   Oncogene 18 (48), 6621-6634 (1999)
   PUBMED   10597267
REFERENCE   9  (bases 1 to 5148)
  AUTHORS   Gupta,K., Anand,G., Yin,X., Grove,L. and Prochownik,E.V.
  TITLE     Mmip1: a novel leucine zipper protein that reverses the suppressive
            effects of Mad family members on c-myc
  JOURNAL   Oncogene 16 (9), 1149-1159 (1998)
   PUBMED   9528857
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AY854011.1.
            
            On Apr 22, 2006 this sequence version replaced NM_013894.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AY854011.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849384, SAMN01164134
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..5148
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10090"
                     /chromosome="14"
                     /map="14 28.21 cM"
     gene            1..5148
                     /gene="Rnf17"
                     /gene_synonym="MMIP-2; Mmip2; TDRD4"
                     /note="ring finger protein 17"
                     /db_xref="GeneID:30054"
                     /db_xref="MGI:MGI:1353419"
     exon            1..128
                     /gene="Rnf17"
                     /gene_synonym="MMIP-2; Mmip2; TDRD4"
                     /inference="alignment:Splign:2.1.0"
     exon            129..223
                     /gene="Rnf17"
                     /gene_synonym="MMIP-2; Mmip2; TDRD4"
                     /inference="alignment:Splign:2.1.0"
     exon            224..315
                     /gene="Rnf17"
                     /gene_synonym="MMIP-2; Mmip2; TDRD4"
                     /inference="alignment:Splign:2.1.0"
     exon            316..427
                     /gene="Rnf17"
                     /gene_synonym="MMIP-2; Mmip2; TDRD4"
                     /inference="alignment:Splign:2.1.0"
     exon            428..499
                     /gene="Rnf17"
                     /gene_synonym="MMIP-2; Mmip2; TDRD4"
                     /inference="alignment:Splign:2.1.0"
     exon            500..600
                     /gene="Rnf17"
                     /gene_synonym="MMIP-2; Mmip2; TDRD4"
                     /inference="alignment:Splign:2.1.0"
     exon            601..772
                     /gene="Rnf17"
                     /gene_synonym="MMIP-2; Mmip2; TDRD4"
                     /inference="alignment:Splign:2.1.0"
     exon            773..849
                     /gene="Rnf17"
                     /gene_synonym="MMIP-2; Mmip2; TDRD4"
                     /inference="alignment:Splign:2.1.0"
     exon            850..924
                     /gene="Rnf17"
                     /gene_synonym="MMIP-2; Mmip2; TDRD4"
                     /inference="alignment:Splign:2.1.0"
     exon            925..1229
                     /gene="Rnf17"
                     /gene_synonym="MMIP-2; Mmip2; TDRD4"
                     /inference="alignment:Splign:2.1.0"
     exon            1230..1319
                     /gene="Rnf17"
                     /gene_synonym="MMIP-2; Mmip2; TDRD4"
                     /inference="alignment:Splign:2.1.0"
     exon            1320..1478
                     /gene="Rnf17"
                     /gene_synonym="MMIP-2; Mmip2; TDRD4"
                     /inference="alignment:Splign:2.1.0"
     exon            1479..1668
                     /gene="Rnf17"
                     /gene_synonym="MMIP-2; Mmip2; TDRD4"
                     /inference="alignment:Splign:2.1.0"
     exon            1669..1837
                     /gene="Rnf17"
                     /gene_synonym="MMIP-2; Mmip2; TDRD4"
                     /inference="alignment:Splign:2.1.0"
     exon            1838..2028
                     /gene="Rnf17"
                     /gene_synonym="MMIP-2; Mmip2; TDRD4"
                     /inference="alignment:Splign:2.1.0"
     exon            2029..2170
                     /gene="Rnf17"
                     /gene_synonym="MMIP-2; Mmip2; TDRD4"
                     /inference="alignment:Splign:2.1.0"
     exon            2171..2324
                     /gene="Rnf17"
                     /gene_synonym="MMIP-2; Mmip2; TDRD4"
                     /inference="alignment:Splign:2.1.0"
     exon            2325..2440
                     /gene="Rnf17"
                     /gene_synonym="MMIP-2; Mmip2; TDRD4"
                     /inference="alignment:Splign:2.1.0"
     exon            2441..2558
                     /gene="Rnf17"
                     /gene_synonym="MMIP-2; Mmip2; TDRD4"
                     /inference="alignment:Splign:2.1.0"
     exon            2559..2676
                     /gene="Rnf17"
                     /gene_synonym="MMIP-2; Mmip2; TDRD4"
                     /inference="alignment:Splign:2.1.0"
     exon            2677..2904
                     /gene="Rnf17"
                     /gene_synonym="MMIP-2; Mmip2; TDRD4"
                     /inference="alignment:Splign:2.1.0"
     exon            2905..3055
                     /gene="Rnf17"
                     /gene_synonym="MMIP-2; Mmip2; TDRD4"
                     /inference="alignment:Splign:2.1.0"
     exon            3056..3174
                     /gene="Rnf17"
                     /gene_synonym="MMIP-2; Mmip2; TDRD4"
                     /inference="alignment:Splign:2.1.0"
     exon            3175..3265
                     /gene="Rnf17"
                     /gene_synonym="MMIP-2; Mmip2; TDRD4"
                     /inference="alignment:Splign:2.1.0"
     exon            3266..3381
                     /gene="Rnf17"
                     /gene_synonym="MMIP-2; Mmip2; TDRD4"
                     /inference="alignment:Splign:2.1.0"
     exon            3382..3668
                     /gene="Rnf17"
                     /gene_synonym="MMIP-2; Mmip2; TDRD4"
                     /inference="alignment:Splign:2.1.0"
     exon            3669..3832
                     /gene="Rnf17"
                     /gene_synonym="MMIP-2; Mmip2; TDRD4"
                     /inference="alignment:Splign:2.1.0"
     exon            3833..3952
                     /gene="Rnf17"
                     /gene_synonym="MMIP-2; Mmip2; TDRD4"
                     /inference="alignment:Splign:2.1.0"
     exon            3953..4033
                     /gene="Rnf17"
                     /gene_synonym="MMIP-2; Mmip2; TDRD4"
                     /inference="alignment:Splign:2.1.0"
     exon            4034..4159
                     /gene="Rnf17"
                     /gene_synonym="MMIP-2; Mmip2; TDRD4"
                     /inference="alignment:Splign:2.1.0"
     exon            4160..4216
                     /gene="Rnf17"
                     /gene_synonym="MMIP-2; Mmip2; TDRD4"
                     /inference="alignment:Splign:2.1.0"
     exon            4217..4333
                     /gene="Rnf17"
                     /gene_synonym="MMIP-2; Mmip2; TDRD4"
                     /inference="alignment:Splign:2.1.0"
     exon            4334..4502
                     /gene="Rnf17"
                     /gene_synonym="MMIP-2; Mmip2; TDRD4"
                     /inference="alignment:Splign:2.1.0"
     exon            4503..4638
                     /gene="Rnf17"
                     /gene_synonym="MMIP-2; Mmip2; TDRD4"
                     /inference="alignment:Splign:2.1.0"
     exon            4639..4828
                     /gene="Rnf17"
                     /gene_synonym="MMIP-2; Mmip2; TDRD4"
                     /inference="alignment:Splign:2.1.0"
     exon            4829..4928
                     /gene="Rnf17"
                     /gene_synonym="MMIP-2; Mmip2; TDRD4"
                     /inference="alignment:Splign:2.1.0"
     exon            4929..5148
                     /gene="Rnf17"
                     /gene_synonym="MMIP-2; Mmip2; TDRD4"
                     /inference="alignment:Splign:2.1.0"
     regulatory      5126..5131
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Rnf17"
                     /gene_synonym="MMIP-2; Mmip2; TDRD4"
                     /note="hexamer: AATAAA"
     polyA_site      5148
                     /gene="Rnf17"
                     /gene_synonym="MMIP-2; Mmip2; TDRD4"
                     /note="major polyA site"
ORIGIN      
        1 agcaatggcg gcagaggctt cgtcgaccgg gctggcttcc tgtcacctag tggagagtaa
       61 gagtggagcg cagggtgctt cggggtgtca gtgcactcgg tgtggaagga aggtgtccgt
      121 tgcctccggt gaccaccaca agtttccatg tggacatgcc ttttgtgaac tgtgcctgtt
      181 agcacctcaa gaatatacca caagtaaatg cactgactgt gaggttcata caactgtcag
      241 catgaatcaa ggtcactacc cagtagatgg cttcatcgag gaagattctt ctctggaagc
      301 cttgccaccg aaaatggtaa ataactgctc ttcagatctt gaaaagacag tggaccagct
      361 aattaatgat ttagaacatt catcctccat acataggaat gtttcaaacc catcagctgt
      421 aatgtcggag acagaagaaa ttgatgaagc actgaagata gcaggctgta attttgaaca
      481 attaagtaat gctataaaaa tgcttgatag cacacaagat caaacaagac aagagacaca
      541 cagtctaaca gaggctgtgg agaaacagtt tgatacactt cttgcttctc ttgattccag
      601 gaaaaagagc ttgtgtgaag aacttataag gcgtacagat gattatttat caaaattagt
      661 aacagttaaa agctacattg aagagaaaaa aagtgatttg gatgcagcta tgaagatagc
      721 aaaagaactc agatctgctc cttctctgag gacctactgt gacctgactc agattatccg
      781 gactttgaag ttaacatttg aaagtgaatt gtcacaagtt agttccataa ttccaaggaa
      841 cacccctagg ttggatataa attgcagtga ggccatctgc atgttcagca gtatgggaaa
      901 gattgaattt gaggactcaa caaaatgtta ccctcaagaa aatgaagatg gacagaatgt
      961 tcaaaagaaa tttaataata gaaaggaact ctgttgtgat gtatactcat cactagaaaa
     1021 gaaaaaggta gatgctgctg tcctgactga tgaaacacct gaacctcctt tgcaagcaga
     1081 ggcccctgac aggcatttag aagggaaaaa gaagcagcca acaaaagaga tggttgtggt
     1141 gacatctcct aagactattg ctgtactgcc tcaactggga tccagccctg atgtgataat
     1201 tgaggaaatt attgaggaaa acctagaatc atgctttaca gatgatccta tagagacttc
     1261 tggataccca aaaaagcccc ctcagaaaga gcagtctgct cctgttggat caaaagcagg
     1321 ttgtccagag ctagtttttg taagtcatgt aatacatcct tgccacttct atgtgcggaa
     1381 atattcacaa ataaaagatg caacaatatt ggagaagaag atgaagcaag tttgcaatag
     1441 gagcttacac cttgatcctt cagacatttt ggaactaggt gcaagaatat ttgtcaacag
     1501 tattaagaat agaatgtggt gtcgaggaat tatcactgaa ataattccat caaaaactaa
     1561 aaatattaga aaaccatgta gtccaaccaa attctcagtc tgtgaaattt cactaataca
     1621 gatattcatg gtagattttg gaaattctga agtcctgatc atcacaggag ttggtgacac
     1681 acatgaggga ccagagcatg atggtgaaca gcatattaca ctaagtgact tctgtctgct
     1741 tctaatgaag tctgaaccat acagtgagga actgttgaaa gacatcccac atttagcaca
     1801 cctgtgctcc ttgaaagaca tcgtcccata caattcaact gagggctggg aaaaggaggc
     1861 aaaagtggaa tttttgaaaa tggtaaataa gaaggctgtc ttaatgaaag tttttggaga
     1921 agaagatgat gtccttattg tagatctgca gaaaccacca acaaataaaa tcagcagtga
     1981 tatgcctgtg tctctcagag atgcattggt ttttatggaa ctagcaaggt ttaggtcaca
     2041 atcaccaaga agtcacagtg aaaaaaatac aactttatgc tatcatccac ccattttgcc
     2101 tgaagagatg actgaagttt cagtcatggt ttgccatata aatagtccta ctgattttta
     2161 tcttcagctg atggagaacc tggacttttt atctctttta aaaacaattg aggaattcta
     2221 taaaggtgaa gatggagaaa atctggaaat cctttgtcct cttcagaatc aagcctgtgt
     2281 agctaaattt gaagatggaa tctggtatcg tgcaaaagtg atcggattgc ctggacatcg
     2341 ggaagtagaa gttaaatatg tggactttgg taatactgca aaaataacac ttaaagatat
     2401 gcggaaaata aaggatgagt ttttggaacc cccagagaag gcaattaaat gtaagctggc
     2461 atatgttgaa ccaagtaaaa aatcacagtg gtccaaaaag gctaaagaga aatttgaaga
     2521 aaagactcaa gataaatttg tgacatgttc tgttattaag attctggaaa ataatgtgct
     2581 cttggttgag ctttttgatt ctcgagctcc tggaaaaagt gctgttagta ttaatgacca
     2641 gctcgtgaaa gagggcctag catcttatga agcaggatat accctcaaag ataactctaa
     2701 aaagcatctt gaagtatggg atccttctcc tgaagaaatt attacaagtg aaataaacaa
     2761 cttaagtcct ttatctgtaa aatctctacc taatgagaat ttccagtcat tgtataacaa
     2821 ggagctgcct gtgaacatat gtaatgtaat atctcctgag aagatttatg ttcagtggtt
     2881 attaacagaa aacttactta atagtttaga agagaagatg gtagcagcgt atgagcactc
     2941 agaatggaag cctgttaagt gggagtgtga tatgcactgc gctgttaagg tcccagctaa
     3001 aaatcagtgg cgaagaggcc agattctcag aatggttaca gacaaactgg tagaggtctt
     3061 gctttatgat gttggtgttg aactagtagt gaatattcac tgcttaagag aacttcaaga
     3121 aaatctaaag acaatgggaa gattatcttt ggaatgttca cttgttgata taaggccaac
     3181 tggcggaagt gacaagtgga cagcaacagc ttgtgactgt ctgtcactgc acctcactgg
     3241 agccatagca accataatct tacaggaaag caacacaacg tggccattac ctgtgaaaat
     3301 tttctgccga gatgaaaaag gagaacgtgt tgatgtttct aaatatttga ttaaaaaagg
     3361 tttggcattg agagagagaa gagttagtaa atcaagtaac agccattcac ctgagaagtc
     3421 tctggaaata cccctggagc aaggagattc agtagttact aagtgcttta aaattaactt
     3481 tgatactaac aagaaaattg ctgataaagt caatgaacac aaagtacctg attctaaggg
     3541 aaagaaatca gaaagcagaa gcaccggatg ctatagacca ccagctgttc ctaacacgag
     3601 ttcatttgag gcaatagtga cctgcattgg tgacgatgga actatatttg tagtgcctaa
     3661 attatcagaa tttgagctca taaaaatgat ggatgaaatt caaagtaatt taaagtgcct
     3721 tggtcttttg gagccatatt cctggaaaaa gggagagcct tgtgcagtga gaggatctga
     3781 tactttgtgg taccgtggca aagttatgga ggttgtggga ggcaccatca gggtccagta
     3841 tttagatcat gggttcactg agaagattcc acaatgtcat ctgtatccta ttttgctcta
     3901 tcctgatact ccccagttct gtattccctg tcagctctat cagactttac cggttgggaa
     3961 tacctggcag ccagatgcca tagagctgct tcaggagctg ctttcaaaga gagaggtgga
     4021 cattcacatt atggaattgc ccaacaattc atgggggaag ttgtctgtcc atctctattt
     4081 tgatgggatg tcactttctc attttatggc ccatcataaa tactgtattt ttgaacatac
     4141 cgaggagata tttaaagaaa aaccaagagg tcagaataaa aagtatgaag atgaaaactg
     4201 gaaaataaga tttgaggact tgcttttgcc tgaaatggag gctcccgttt taccaccgta
     4261 tctgtcttcc cttctgcctc caccagagga gctgtttgcc gtgcaagtga agcacattgt
     4321 ctcaccggat gaaatgtata tttgccttga ctctgaagat agctatactc agtttaacca
     4381 tcatggtgac acggatgaca gtggagtcag ctgggagtca gagtcagaga acctggagga
     4441 agcgctgcag agatttaaca agaacgtgga gacgtttcct cccctgacgg attttagctc
     4501 agagatgcct tgccttgcag aatatgctga tggtttgtgg tatagagcaa agatcatttc
     4561 cattaaagaa tttaaccctt tatctgtcct ggtactgttt gttgattatg gttgcacaga
     4621 gaagttgaca ataaacagac tacgtcagat tcctgttcag cttatgcagt acccagccca
     4681 agccataaag gtgctcttgg cagggtttaa acctccctta agtgactcgg gaaaaacaag
     4741 aataccatac tgtcccaaat ggagcatgga agccttgtgg actatgatag actgtctcca
     4801 aggaaaacaa ctttatgctt cttctgtggc tcaggcacca gaacaaatag tgacattata
     4861 tgaagatgaa caatacccag ttcacatgtc cttggtagaa atggggcttg cagataaaga
     4921 tgaatgatgt gcacaagagc tcctgcagct gtccagaaaa aaagttttct gttagatttg
     4981 taccacttca ggtttgattt taacttgttc tgcagtggta tcagtttttt tcctccttta
     5041 gtcttacttg gtaaattgtt aaggaatggt gtggtgaaaa gttaatattt tctttaaaac
     5101 gtttttgttt ttactgtcct ttcaaaataa aatttagtca tatagaaa
//
