LOCUS       NM_027445               1893 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Mus musculus ring finger protein 167 (Rnf167), transcript variant
            1, mRNA.
ACCESSION   NM_027445 XM_001471737
VERSION     NM_027445.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1893)
  AUTHORS   Lussier,M.P., Herring,B.E., Nasu-Nishimura,Y., Neutzner,A.,
            Karbowski,M., Youle,R.J., Nicoll,R.A. and Roche,K.W.
  TITLE     Ubiquitin ligase RNF167 regulates AMPA receptor-mediated synaptic
            transmission
  JOURNAL   Proc Natl Acad Sci U S A 109 (47), 19426-19431 (2012)
   PUBMED   23129617
  REMARK    GeneRIF: RNF167 is a selective regulator of AMPAR-mediated
            neurotransmission.
REFERENCE   2  (bases 1 to 1893)
  AUTHORS   Taher,L., Collette,N.M., Murugesh,D., Maxwell,E., Ovcharenko,I. and
            Loots,G.G.
  TITLE     Global gene expression analysis of murine limb development
  JOURNAL   PLoS One 6 (12), e28358 (2011)
   PUBMED   22174793
REFERENCE   3  (bases 1 to 1893)
  AUTHORS   Evsikov,A.V., Graber,J.H., Brockman,J.M., Hampl,A., Holbrook,A.E.,
            Singh,P., Eppig,J.J., Solter,D. and Knowles,B.B.
  TITLE     Cracking the egg: molecular dynamics and evolutionary aspects of
            the transition from the fully grown oocyte to embryo
  JOURNAL   Genes Dev 20 (19), 2713-2727 (2006)
   PUBMED   17015433
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL596117.19, AK017523.1, DV662846.1, DV655579.1 and AI840160.1.
            
            On May 9, 2018 this sequence version replaced NM_027445.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC010777.1, AK154071.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-52                AL596117.19        14599-14650
            53-572              AK017523.1         2-521
            573-1372            DV662846.1         13-812
            1373-1779           DV655579.1         160-566
            1780-1893           AI840160.1         1-114               c
FEATURES             Location/Qualifiers
     source          1..1893
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="11"
                     /map="11 43.21 cM"
     gene            1..1893
                     /gene="Rnf167"
                     /gene_synonym="0610010G05Rik; 5730408C10Rik"
                     /note="ring finger protein 167"
                     /db_xref="GeneID:70510"
                     /db_xref="MGI:MGI:1917760"
     exon            1..718
                     /gene="Rnf167"
                     /gene_synonym="0610010G05Rik; 5730408C10Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             635..1678
                     /gene="Rnf167"
                     /gene_synonym="0610010G05Rik; 5730408C10Rik"
                     /EC_number="2.3.2.27"
                     /note="isoform 1 precursor is encoded by transcript
                     variant 1; E3 ubiquitin-protein ligase RNF167; novel PA
                     domain and C3HC4 type zinc finger (RING finger) containing
                     protein; RING-type E3 ubiquitin transferase RNF167"
                     /codon_start=1
                     /product="E3 ubiquitin-protein ligase RNF167 isoform 1
                     precursor"
                     /protein_id="NP_081721.1"
                     /db_xref="CCDS:CCDS24959.1"
                     /db_xref="GeneID:70510"
                     /db_xref="MGI:MGI:1917760"
                     /translation="MHPAAFPLPVVVATVLWGAAPVRGLIRATSEHNASMDFADLPAL
                     FGATLSDEGLQGFLVEAHPENACGPIAPPPSAPVNGSVFIALLRRFDCNFDLKVLNAQ
                     KAGYGAAVVHNVNSNELLNMVWNSEEIQQQIWIPSVFIGERSAEYLRALFVYEKGARV
                     LLVPDNSFPLGYYLIPFTGIVGLLVLAMGTVLIVRCIQHRKRLQRNRLTKEQLKQIPT
                     HDYQKGDEYDVCAICLDEYEDGDKLRVLPCAHAYHSRCVDPWLTQTRKTCPICKQPVH
                     RGPGDEEQEEETQEQEEGDEGEPRDQPASEWTPLLGSSPTLPTSFGSLAPAPLVFPGP
                     STDPSPPSSAALA"
     exon            719..799
                     /gene="Rnf167"
                     /gene_synonym="0610010G05Rik; 5730408C10Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            800..925
                     /gene="Rnf167"
                     /gene_synonym="0610010G05Rik; 5730408C10Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            926..1013
                     /gene="Rnf167"
                     /gene_synonym="0610010G05Rik; 5730408C10Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1014..1104
                     /gene="Rnf167"
                     /gene_synonym="0610010G05Rik; 5730408C10Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1105..1210
                     /gene="Rnf167"
                     /gene_synonym="0610010G05Rik; 5730408C10Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1211..1304
                     /gene="Rnf167"
                     /gene_synonym="0610010G05Rik; 5730408C10Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1305..1385
                     /gene="Rnf167"
                     /gene_synonym="0610010G05Rik; 5730408C10Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1386..1885
                     /gene="Rnf167"
                     /gene_synonym="0610010G05Rik; 5730408C10Rik"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ggtggggggg tggagggagg gtggtggcaa gcactctcgc gatactttga acgtaccgtg
       61 gcggccagac gaaggagagg tttgtaaaca gggcagctcc aggatctcag ggactgaggg
      121 aaaaaaacta gatcgtctcc tgagcatcga agctccctcc atctccgcag gctccttcta
      181 catgtcaaac atttctttca accggcctct cgggaccgga agtcctccgt cctgagcgtc
      241 caatactgga attggccttt cttaccggaa acccttttcc aggggcatag gaagacagtc
      301 tacctggccg gaagtcccac ctctttgagg tttctcctac ccttccggaa gtttttttgt
      361 tgttgttgtt acctgtttgc cttcgctcct attctgtcct atttctgtac tagagaaaga
      421 tacattgtct cccctaccag ctccgctaag ctggtttgat agctcactcc ctgaatcgga
      481 gttccttccc cgacgccccc atgtagctga gaagtgggac ctaggggtgg ttggacccct
      541 gggatcctga aggagaggca gaggagggcg caggactcgg cttctgctcc tgcgatcaga
      601 acgcgacctt cgcagcttta cccctcccgc tgccatgcac cctgcggcct tcccgcttcc
      661 tgttgtcgtg gctactgtac tgtggggagc agcccctgtc cgagggctga ttcgagcgac
      721 ttcggagcac aatgccagca tggactttgc agaccttcca gctctgtttg gggccactct
      781 gagcgacgag ggactgcagg ggttccttgt ggaggcccac ccagaaaatg cctgcggtcc
      841 tattgcccca ccaccctcag ccccggtcaa tgggtcagtc tttattgcac tgcttcgaag
      901 attcgactgc aactttgacc tcaaggtcct aaatgctcag aaggctgggt atggtgcagc
      961 tgtggtgcac aatgtgaatt ccaatgaact gctgaacatg gtgtggaaca gcgaggaaat
     1021 ccaacagcag atctggatcc catctgtatt tattggagag agaagcgcag agtacctacg
     1081 agcccttttt gtctacgaga agggggctcg ggtgcttctg gttccagaca acagcttccc
     1141 cttgggctat tacctcattc ctttcactgg gattgtagga ttactggttt tggccatggg
     1201 aacagtattg atagttcgtt gcatccagca ccggaaacgg cttcagcgga accgacttac
     1261 caaagagcaa ctgaaacaga ttcctaccca tgactatcag aaaggagatg aatatgacgt
     1321 ctgtgccatc tgtctggatg aatatgagga tggggacaag cttcgagtac ttccctgtgc
     1381 tcatgcttat cacagtcgct gtgtggaccc ctggctcact cagacccgca agacctgccc
     1441 catctgcaaa cagcctgtac atcggggtcc tggcgatgag gagcaggaag aagaaactca
     1501 agagcaagag gaaggcgatg aaggggagcc aagggaccaa cctgcttcag aatggacccc
     1561 actcctgggc tctagcccta ctcttcccac ctcctttgga tccctagccc ctgctcccct
     1621 ggtcttccct gggccctcca cagatccctc acctccttca tctgctgccc tggcctgaca
     1681 cccccatact tggtacctct ggtgaccgtc ctatttgcac aaactctttt tccagtctaa
     1741 taagctgagg gtgagggata ggggacattc taccccaggt tcatgaaccc agcctcatcc
     1801 ttttgagggg gctagaagcc atagggacat ggttttcatt tcttggatta ataaaattgg
     1861 tttttttttg tggatgaaaa aaaaaaaaaa aaa
//
