LOCUS       NM_198251               1308 bp    mRNA    linear   ROD 02-MAY-2024
DEFINITION  Mus musculus ring finger protein 133 (Rnf133), mRNA.
ACCESSION   NM_198251
VERSION     NM_198251.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1308)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 1308)
  AUTHORS   Nozawa,K., Fujihara,Y., Devlin,D.J., Deras,R.E., Kent,K.,
            Larina,I.V., Umezu,K., Yu,Z., Sutton,C.M., Ye,Q., Dean,L.K.,
            Emori,C., Ikawa,M., Garcia,T.X. and Matzuk,M.M.
  TITLE     The testis-specific E3 ubiquitin ligase RNF133 is required for
            fecundity in mice
  JOURNAL   BMC Biol 20 (1), 161 (2022)
   PUBMED   35831855
  REMARK    GeneRIF: The testis-specific E3 ubiquitin ligase RNF133 is required
            for fecundity in mice.
            Publication Status: Online-Only
REFERENCE   3  (bases 1 to 1308)
  AUTHORS   Koscielny,G., Yaikhom,G., Iyer,V., Meehan,T.F., Morgan,H.,
            Atienza-Herrero,J., Blake,A., Chen,C.K., Easty,R., Di Fenza,A.,
            Fiegel,T., Grifiths,M., Horne,A., Karp,N.A., Kurbatova,N.,
            Mason,J.C., Matthews,P., Oakley,D.J., Qazi,A., Regnart,J.,
            Retha,A., Santos,L.A., Sneddon,D.J., Warren,J., Westerberg,H.,
            Wilson,R.J., Melvin,D.G., Smedley,D., Brown,S.D., Flicek,P.,
            Skarnes,W.C., Mallon,A.M. and Parkinson,H.
  TITLE     The International Mouse Phenotyping Consortium Web Portal, a
            unified point of access for knockout mice and related phenotyping
            data
  JOURNAL   Nucleic Acids Res 42 (Database issue), D802-D809 (2014)
   PUBMED   24194600
REFERENCE   4  (bases 1 to 1308)
  AUTHORS   Nian,H., Zhang,W., Shi,H., Zhao,Q., Xie,Q., Liao,S., Zhang,Y.,
            Zhang,Z., Wang,C. and Han,C.
  TITLE     Mouse RING finger protein Rnf133 is a testis-specific endoplasmic
            reticulum-associated E3 ubiquitin ligase
  JOURNAL   Cell Res 18 (7), 800-802 (2008)
   PUBMED   18574499
  REMARK    GeneRIF: Study identified a potential testis-specific gene named
            Rnf133.
REFERENCE   5  (bases 1 to 1308)
  AUTHORS   Borchers,A.G., Hufton,A.L., Eldridge,A.G., Jackson,P.K.,
            Harland,R.M. and Baker,J.C.
  TITLE     The E3 ubiquitin ligase GREUL1 anteriorizes ectoderm during Xenopus
            development
  JOURNAL   Dev Biol 251 (2), 395-408 (2002)
   PUBMED   12435366
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AK028082.1.
            
            [WARNING] On Jan 31, 2025 this sequence was replaced by
            NM_198251.3.
            
            On Apr 5, 2007 this sequence version replaced NM_198251.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK028082.1, AV045338.3 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849384 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-1308              AK028082.1         2-1309
FEATURES             Location/Qualifiers
     source          1..1308
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="6"
                     /map="6 11.01 cM"
     gene            1..1308
                     /gene="Rnf133"
                     /gene_synonym="Greul2"
                     /note="ring finger protein 133"
                     /db_xref="GeneID:386611"
                     /db_xref="MGI:MGI:2677436"
     exon            1..726
                     /gene="Rnf133"
                     /gene_synonym="Greul2"
                     /inference="alignment:Splign:2.1.0"
     CDS             249..1268
                     /gene="Rnf133"
                     /gene_synonym="Greul2"
                     /EC_number="2.3.2.27"
                     /note="goliath-related E3 ubiquitin-protein ligase 2;
                     RING-type E3 ubiquitin transferase RNF133"
                     /codon_start=1
                     /product="E3 ubiquitin-protein ligase RNF133"
                     /protein_id="NP_937894.1"
                     /db_xref="CCDS:CCDS19938.1"
                     /db_xref="GeneID:386611"
                     /db_xref="MGI:MGI:2677436"
                     /translation="MNPLQTSTWQNQAPSFWLLRFSFIWLVSQKCCTASAVWTAYMNI
                     SFHVGNRMLSELGETGVFGRSSILKRVAGVVVPPEGKIQNACDPNTTFILPRNKEPWI
                     ALIERGGCAFTQKIKVASEHGARGVIIYNFPGTGNQVFPMSHQAFEDIVVVMIGNIKA
                     YFTFYHIRRLWVARIENRRWKRLTRELKKAFGQLQVRVLKEGDEEVNPNADSCVICFE
                     AYKPNEIVRILTCKHFFHKNCIDPWILAHGTCPMCKCDILKALGIQMDIEDGTDSLQV
                     LMSNELPGTLSPVEEETNYELPPARTSSKVTHVQEHPTSSANAGSQPPEAEETSHPSH
                     GQQVL"
     exon            727..1308
                     /gene="Rnf133"
                     /gene_synonym="Greul2"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 aagcagtatc taaagttaca gcagtgagac aggaatttct ttactatcta aagcttttct
       61 ctctaataaa acatctgaaa ctcaagacat ctttagaaag ctcttgctga aacatgctgg
      121 aagacagtgt atcttatttt cacccagaag atattttctc cttcctcatt ctgaattgat
      181 tgtcaacaga tgtggcagct gtgccggtta gttgggttgg ctattcaagt cattcgtgaa
      241 gtacagtgat gaatcctctt cagaccagta cttggcaaaa ccaagctcca tctttctggc
      301 ttctgagatt cagttttatc tggctcgtca gtcagaaatg ttgtacagcc agtgcagttt
      361 ggactgcgta catgaacata tcatttcatg tggggaaccg catgctgtca gagctggggg
      421 agaccggggt cttcggaaga agctccatct tgaagagagt agcaggagtt gttgtgccac
      481 cagagggaaa aattcaaaat gcttgtgatc ccaataccac ttttatcctg ccacggaaca
      541 aagagccctg gatcgcactc attgaacggg gaggttgtgc cttcacacag aaaattaagg
      601 tggcatctga gcacggagcc agaggagtga tcatctataa tttcccaggt actggcaacc
      661 aggttttccc catgtctcac caggcgtttg aagacatcgt tgtagttatg attggtaaca
      721 tcaaagcata tttcaccttt tatcacattc ggagactttg ggtggcaaga attgagaaca
      781 ggagatggaa gcgattaaca agagagctca agaaagcttt tgggcagctg caagttcgag
      841 tattaaaaga aggggatgaa gaagttaatc caaatgctga cagctgtgtc atctgctttg
      901 aagcctataa gcctaatgaa atagttcgga ttctcacttg caaacatttt ttccacaaga
      961 attgcattga cccctggatt ctagcccacg gcacatgccc catgtgcaaa tgtgacattc
     1021 tgaaagctct ggggattcag atggacattg aggatgggac agactctctg caagttctga
     1081 tgtcaaatga attgcccgga accttgtcac ccgtggaaga agagacgaac tatgagcttc
     1141 ctcctgcaag aacttcaagt aaagtgaccc acgtgcagga gcaccctact tcttctgcga
     1201 acgctggcag ccagcctccc gaagcagagg aaaccagtca tccttcacat ggacagcaag
     1261 tcctttgagc aagtggatta aacctgtttg tcagatcagg tcctcgtg
//
