LOCUS       NM_001368375            5414 bp    mRNA    linear   ROD 01-AUG-2024
DEFINITION  Mus musculus ring finger protein 122 (Rnf122), transcript variant
            3, mRNA.
ACCESSION   NM_001368375 XM_006509190
VERSION     NM_001368375.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 5414)
  AUTHORS   Bedogni,F. and Hevner,R.F.
  TITLE     Cell-Type-Specific Gene Expression in Developing Mouse Neocortex:
            Intermediate Progenitors Implicated in Axon Development
  JOURNAL   Front Mol Neurosci 14, 686034 (2021)
   PUBMED   34321999
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5414)
  AUTHORS   Wang,W., Jiang,M., Liu,S., Zhang,S., Liu,W., Ma,Y., Zhang,L.,
            Zhang,J. and Cao,X.
  TITLE     RNF122 suppresses antiviral type I interferon production by
            targeting RIG-I CARDs to mediate RIG-I degradation
  JOURNAL   Proc Natl Acad Sci U S A 113 (34), 9581-9586 (2016)
   PUBMED   27506794
  REMARK    GeneRIF: RNF122 suppresses antiviral type I interferon production
            by targeting RIG-I caspase activation and recruitment domains to
            mediate RIG-I degradation.
REFERENCE   3  (bases 1 to 5414)
  AUTHORS   Piao,Y., Ko,N.T., Lim,M.K. and Ko,M.S.
  TITLE     Construction of long-transcript enriched cDNA libraries from
            submicrogram amounts of total RNAs by a universal PCR amplification
            method
  JOURNAL   Genome Res 11 (9), 1553-1558 (2001)
   PUBMED   11544199
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC109163.16.
            
            On Feb 8, 2019 this sequence version replaced XM_006509190.3.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK171823.1, AK077856.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-346               AC109163.16        96302-96647
            347-503             AC109163.16        102906-103062
            504-549             AC109163.16        109327-109372
            550-591             AC109163.16        109641-109682
            592-674             AC109163.16        112727-112809
            675-5414            AC109163.16        113054-117793
FEATURES             Location/Qualifiers
     source          1..5414
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="8"
                     /map="8 17.97 cM"
     gene            1..5414
                     /gene="Rnf122"
                     /gene_synonym="1110063C11Rik"
                     /note="ring finger protein 122"
                     /db_xref="GeneID:68867"
                     /db_xref="MGI:MGI:1916117"
     exon            1..346
                     /gene="Rnf122"
                     /gene_synonym="1110063C11Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             322..789
                     /gene="Rnf122"
                     /gene_synonym="1110063C11Rik"
                     /note="isoform 3 is encoded by transcript variant 3; ring
                     finger protein 122 homolog"
                     /codon_start=1
                     /product="RING finger protein 122 isoform 3"
                     /protein_id="NP_001355304.1"
                     /db_xref="CCDS:CCDS90381.1"
                     /db_xref="GeneID:68867"
                     /db_xref="MGI:MGI:1916117"
                     /translation="MHPFQWCNGCFCGLGLVSTNKSCSMPPISFQDLPLNIYMVIFGT
                     GIFVFMLSLIFCCYFISKLRNQAQSERYGYKEVVLKGDAKKLQLYGQTCAVCLEDFKG
                     KDELGVLPCQHAFHRKCLVKWLEVRCVCPMCNKPIAGPTETSQSIGILLDELV"
     exon            347..503
                     /gene="Rnf122"
                     /gene_synonym="1110063C11Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            504..549
                     /gene="Rnf122"
                     /gene_synonym="1110063C11Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            550..591
                     /gene="Rnf122"
                     /gene_synonym="1110063C11Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            592..674
                     /gene="Rnf122"
                     /gene_synonym="1110063C11Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            675..5414
                     /gene="Rnf122"
                     /gene_synonym="1110063C11Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1734..1739
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Rnf122"
                     /gene_synonym="1110063C11Rik"
                     /note="hexamer: ATTAAA"
     polyA_site      1760
                     /gene="Rnf122"
                     /gene_synonym="1110063C11Rik"
                     /note="major polyA site"
     regulatory      4144..4149
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Rnf122"
                     /gene_synonym="1110063C11Rik"
                     /note="hexamer: AATGAA"
     polyA_site      4167
                     /gene="Rnf122"
                     /gene_synonym="1110063C11Rik"
     regulatory      4941..4946
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Rnf122"
                     /gene_synonym="1110063C11Rik"
                     /note="hexamer: AATAAA"
     polyA_site      4984
                     /gene="Rnf122"
                     /gene_synonym="1110063C11Rik"
     regulatory      5397..5402
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Rnf122"
                     /gene_synonym="1110063C11Rik"
                     /note="hexamer: AAGAAA"
     polyA_site      5414
                     /gene="Rnf122"
                     /gene_synonym="1110063C11Rik"
ORIGIN      
        1 gtcagttttc ggaatcccag cgcgcactgc tcagcgcagt gggacccaag cccggcttcg
       61 tgtcctggct actgccttct cggccgggca tcccggctct ctcggctgcc ctcccggccc
      121 gggccctcgg tagggcttcg ctccgaaaag actttgcttc ctcctctgcc ctctttgttg
      181 ctctgcaaac cggcctctct gtaacccttg actccactcc tccgggagtt gcatctccat
      241 cccggcggtc tcagtgcaca gcccctccag ctccaacacc ttgcctcggt ttgctcccgg
      301 aagccgacct tgacttcatt gatgcaccca ttccagtggt gtaacgggtg tttctgtggc
      361 ctgggactgg ttagtaccaa caagtcctgc tcaatgccac cgatcagttt ccaagacctt
      421 cccctcaata tctacatggt catcttcggc acaggcatct tcgtcttcat gcttagcctc
      481 atcttctgct gctacttcat cagcaaactc cggaaccagg ctcagagcga gcgatacggc
      541 tacaaggagg tggtgcttaa aggtgatgct aagaagttac agctctatgg gcagacctgt
      601 gcagtttgcc tggaagactt caaggggaag gatgaactag gcgtgcttcc atgccagcat
      661 gcctttcacc gcaagtgtct ggtgaagtgg ctagaagtac gttgtgtctg ccccatgtgc
      721 aacaagccca tcgcgggccc cacggagacc tcgcagagca tcgggatcct gctggatgaa
      781 ctggtgtaag cgctcctggc acatggaccc tgggaaagac tgccgacttt gggtacctgg
      841 gtttctctac acaatgaaca agactcacac acacctaaag gcaaggatga cagagccgag
      901 cttctcccag caccgcagga ccagtaccag acttgtccag tctccgcctc ccagggcttc
      961 tctccgttat ccatttccaa tggcctcatc caggtagact gctctatcct ggcactggac
     1021 tgaccgtcca tccagccatc tccacccacc tcatctttgc cctgggaagg agtccactgg
     1081 gtgactgtga ccatgaacgc ctccctttgg acaacaagcg actctgacct tgaaaggctc
     1141 tgccccaccc atgtccttca ctcctgccag agctttcctt gggatggttt ccaagggaaa
     1201 ggagagaaag atcaagaaac caagacgaaa ggctctgtgt gaagtcaagg aaagcagggc
     1261 cctaaaaaag ggaaaaatca atgtttacat gggatgccgg aaacaaaggc cagcctcgcc
     1321 ctggctgact gcagggtgat gggaccagcc ctcccgttag gatctgaggt gctattcatt
     1381 ctctccctgg ccctgcttaa tctcagagcc ttctagtcat cgttggtttg gaagagaccc
     1441 ctctctatag gaaggggtct aatcctcaag cccattgtca ggggcttttt ttttttttct
     1501 ttttggaagc aaaacgggcc tcaggctggg gatggttggg aggataccat agtgcagatg
     1561 tctccttccc ctctgtaaat agtattttta tacttcatct tcaccatcac catctcaggc
     1621 tttacacgtg cagcccctcc cccacccagg atggaggggg gggctgtgga gtgtcccctt
     1681 ccttccctga acagggcggc tgagagtggg aaaaggttat gtatttaaag aaaattaaat
     1741 ttaataacat gtttctctaa tcaaattttt ggcttgtggt tgtggcctgt gccaggagag
     1801 ggaacagagc tctttacctg ccttccccca gtcagaccat acttgaggtt tctaatcctt
     1861 aacaaaacct gagggctgga catctatctc aacaatagag tgcttgggta acatgctcaa
     1921 ggccctgggc tcagtttttg gaatggaaaa aaaaaaaaaa aaagtgggga gggaggatta
     1981 acttattgaa cactggtata aaataagatc tgatgaagcc aggatcaatc gttggaagtt
     2041 ttagaaacat tgtaaagttg atttcaagca cagcattcac tcaactgact tgaattctac
     2101 ctggtggttg attgtcagtg atctggcgac ctcagaggcc catgtagcta ccctggcacc
     2161 ccatctcttt actaatcctg tgtcgctgac agtccctccc tggcacatcc tagcctccta
     2221 cacacatcta gaattccatg tggtagcaac aggtatgacc ctgcgtgcat ccagatcctc
     2281 cacccacagc ctccagctta gctttgccag tttcccaagg ggcctgctgt caacagtgag
     2341 tgcgatcaga atgggatggt gttgggaaca cctttcttaa gcataaggta actagaccct
     2401 ggttggccct tgcttgggag cacaaatcga tgccagtcaa gcaggcagca cgccttgggt
     2461 gctgagctca ggaaagccat ttgctgagca tggtttggat tgatgtcagc tgtgaaaaag
     2521 ctacccatca ttgagtacta gatacctgga gtaggtatag tgctgtctta ctcagccatt
     2581 gtcttatgca tcttggacaa caccaaggtg taattgggta cctgactatg ggctcttcta
     2641 caggaaggtg cctttactct ttacattaag tgacccctgc ttgctattgt caaccttaag
     2701 agaaacagat ctctctccac tgggtcacca cttcctcttc tagcagtgat agtctggaag
     2761 tattgaggaa ttttgatgta ttttctcagc cgatttcagc ctacccctca gttcctgctg
     2821 caggtggatt cactggtgga gaaagtaatc aggttggctt tgtatctccc acctcatcat
     2881 ctctccttgc aactgggagg gttcatcagt gttagcatcc tgatgaaaat gttagcacga
     2941 aaaagcttgt ttcacagctt tcaaaacagt gttaccaggt caaaatgatg tgggggcagg
     3001 aaataccttt tattccccgt gcttctattg aacctgggtg gtatatatta cagagtacac
     3061 agaagggaaa atgatactgg ttagctgatc agctcaactg gcagccgcta agcacaatta
     3121 gacactatgt ccccaattca cacagtcacc tgtgaagtct tgtgacttgg ttaagccttt
     3181 ttagaacacc tgctgcctgg tttggccact tgacaggcaa atcctgacct tggcgaaatg
     3241 gtgtgagcac tgtgcttggg tggcaagctc acataatcga gatctttact cagctgtctt
     3301 ttcagcagca gcccgagtgt atattgccaa gacatgatgc tcaatcagca gcccgagtgt
     3361 atgccaagac atgctcagtc tagggagcag taatgtggac attgactttg attaaccaga
     3421 ctgtggggac cagagagttc aaaccattct gtatgaactg aggtgggaaa gacagtaggt
     3481 tagaacataa agggaggaag tactgtgtgg aagccaggaa caggattgga tagagtaagc
     3541 accctgaact ttatttacat aaaacttaaa aaaaaaaacc cactatgttc catctgagaa
     3601 ctaagcaaat tattctctcc tctgggtcct atatatagcc acaggcagct acaatagacc
     3661 tataactatt caaattagca aagaatgtat accttgaata tatctgaaag ggaaaaagat
     3721 caaaggaagt tgtgttgtga ccagtacatg ccagcttcag caaagaaggg tttttgttct
     3781 ttccccccaa cagaagacat ttttcttgct tctctgaata tactgaattt aggattagtt
     3841 tgtttaaaaa aaaatcggtg ctcacataat tagacactaa gtgtcagcta actaacacaa
     3901 ccccaggcag tgtggatcca aggtcagtgt cactttcctt gccccacagt tttgaaagca
     3961 gatggtgcta aagactctca aagtaccagg tgctgtcaag cctggtgcag tctgggaaga
     4021 caagcctcat cataggcctg tgagctgtac cctagccact gttaggaaca gggcagggtc
     4081 ttggaattta tagtctgtgt ttgattactt gtttaatttg gtgtctcttg tgtttaattc
     4141 cacaatgaat gactttttaa aaaaagattt attatttata tgtatgtata ctgtacctgt
     4201 cttcagacac accagtagag ggtgtcagat gtcattatgg atgattgtaa gccaccatgt
     4261 ggttgctggg atttgaactc aggaccttca gaagaacagt cggtgctctt aacctcgctg
     4321 agctatatct ccagctccca atgaatgact taagtcttaa atagaaccac catttaaaac
     4381 tgggtaaatg aagtgagaca gagctcctct agggaaaaat ttgaaattca gcgatagctt
     4441 gggataatgg tgataggtga atttaaaagt gggctaccac attgggtcac acatgctttt
     4501 aatcctgaca cctgagaggc agaggcaagt ggatctctga atgtgaggcc agcttggtct
     4561 ggtctacata gatagccagg gttatgggga gtggggggag gtgcggggag ggggagaagt
     4621 cacccttcct cttgatagtt ctactcaacc agcacttccc atgtgttcac tagaattttt
     4681 attccttagt tctgtcaaga ttgtccctta tacatgccta ccctccattc tatcacattg
     4741 cccgtctctt tgaacatcag agtaacatcc tgccaggtca ctggaagctc agacttctgt
     4801 tgaagcctca tccacaggtt cggaggggca gatgtgattg agttggagac aagaactgtt
     4861 attatacaaa ttcatgggac atgacgccat ttatcatccc acttaataag cattggattc
     4921 caactgatcc aatccaagaa aataaaaacc atgcccattt cccttctgat gggaagacat
     4981 caaatgtcac ctttgtgttt tgatccgttc cttatgtgac agcttaacaa gaaaccatca
     5041 tgtgctctgt agaggaatag ctagggggac atcagccagg agatatactg gaagacactt
     5101 ttgatggcga ctgagtgttc tcagtcacga ccccccacaa agctcacttt tcttcctctt
     5161 ttttcctcca attttcttca tctattccta ttctctaaca ttactaagat gccatactat
     5221 tgaagaattt tccagatggg ctgtaggtac catgaatggg gctctgagtt ctaaatgttc
     5281 agtaaataag cattgagtct caagggggtg ctgatatcct caaagacatg aatatcattt
     5341 gtgatgtctg gaacattaaa ggaacgatgt agcataaaga agccaataaa aaccagaaga
     5401 aatctctact ggaa
//
