LOCUS       NM_029211               2272 bp    mRNA    linear   ROD 24-OCT-2024
DEFINITION  Mus musculus ring finger protein 121 (Rnf121), transcript variant
            1, mRNA.
ACCESSION   NM_029211
VERSION     NM_029211.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2272)
  AUTHORS   Cheung,B.B., Mittra,R., Murray,J., Wang,Q., Seneviratne,J.A.,
            Raipuria,M., Wong,I.P.L., Restuccia,D., Gifford,A., Salib,A.,
            Sutton,S., Huang,L., Ferdowsi,P.V., Tsang,J., Sekyere,E., Mayoh,C.,
            Luo,L., Brown,D.L., Stow,J.L., Zhu,S., Young,R.J., Solomon,B.J.,
            Chappaz,S., Kile,B., Kueh,A., Herold,M.J., Hilton,D.J., Liu,T.,
            Norris,M.D., Haber,M., Carter,D.R., Parker,M.W. and Marshall,G.M.
  TITLE     Golgi-localized Ring Finger Protein 121 is necessary for
            MYCN-driven neuroblastoma tumorigenesis
  JOURNAL   Commun Biol 7 (1), 1322 (2024)
   PUBMED   39402275
  REMARK    GeneRIF: Golgi-localized Ring Finger Protein 121 is necessary for
            MYCN-driven neuroblastoma tumorigenesis.
            Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2272)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   3  (bases 1 to 2272)
  AUTHORS   Zemirli,N., Pourcelot,M., Dogan,N., Vazquez,A. and Arnoult,D.
  TITLE     The E3 ubiquitin ligase RNF121 is a positive regulator of NF-kappaB
            activation
  JOURNAL   Cell Commun Signal 12, 72 (2014)
   PUBMED   25388546
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 2272)
  AUTHORS   Koscielny,G., Yaikhom,G., Iyer,V., Meehan,T.F., Morgan,H.,
            Atienza-Herrero,J., Blake,A., Chen,C.K., Easty,R., Di Fenza,A.,
            Fiegel,T., Grifiths,M., Horne,A., Karp,N.A., Kurbatova,N.,
            Mason,J.C., Matthews,P., Oakley,D.J., Qazi,A., Regnart,J.,
            Retha,A., Santos,L.A., Sneddon,D.J., Warren,J., Westerberg,H.,
            Wilson,R.J., Melvin,D.G., Smedley,D., Brown,S.D., Flicek,P.,
            Skarnes,W.C., Mallon,A.M. and Parkinson,H.
  TITLE     The International Mouse Phenotyping Consortium Web Portal, a
            unified point of access for knockout mice and related phenotyping
            data
  JOURNAL   Nucleic Acids Res 42 (Database issue), D802-D809 (2014)
   PUBMED   24194600
REFERENCE   5  (bases 1 to 2272)
  AUTHORS   Boon,A.C., deBeauchamp,J., Hollmann,A., Luke,J., Kotb,M., Rowe,S.,
            Finkelstein,D., Neale,G., Lu,L., Williams,R.W. and Webby,R.J.
  TITLE     Host genetic variation affects resistance to infection with a
            highly pathogenic H5N1 influenza A virus in mice
  JOURNAL   J Virol 83 (20), 10417-10426 (2009)
   PUBMED   19706712
REFERENCE   6  (bases 1 to 2272)
  AUTHORS   Girard,A., Sachidanandam,R., Hannon,G.J. and Carmell,M.A.
  TITLE     A germline-specific class of small RNAs binds mammalian Piwi
            proteins
  JOURNAL   Nature 442 (7099), 199-202 (2006)
   PUBMED   16751776
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BY316785.1, AK159260.1, AC167240.5 and BE946466.1.
            
            On Feb 13, 2018 this sequence version replaced NM_029211.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK168821.1, AK169089.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849380, SAMN00849382
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-7                 BY316785.1         2-8
            8-686               AK159260.1         2-680
            687-687             AC167240.5         1083-1083
            688-2056            AK159260.1         682-2050
            2057-2272           BE946466.1         1-216               c
FEATURES             Location/Qualifiers
     source          1..2272
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="7"
                     /map="7 54.71 cM"
     gene            1..2272
                     /gene="Rnf121"
                     /gene_synonym="4930544L10Rik"
                     /note="ring finger protein 121"
                     /db_xref="GeneID:75212"
                     /db_xref="MGI:MGI:1922462"
     exon            1..100
                     /gene="Rnf121"
                     /gene_synonym="4930544L10Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            101..138
                     /gene="Rnf121"
                     /gene_synonym="4930544L10Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            139..280
                     /gene="Rnf121"
                     /gene_synonym="4930544L10Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            281..435
                     /gene="Rnf121"
                     /gene_synonym="4930544L10Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            436..543
                     /gene="Rnf121"
                     /gene_synonym="4930544L10Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            544..664
                     /gene="Rnf121"
                     /gene_synonym="4930544L10Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            665..798
                     /gene="Rnf121"
                     /gene_synonym="4930544L10Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            799..900
                     /gene="Rnf121"
                     /gene_synonym="4930544L10Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            901..2256
                     /gene="Rnf121"
                     /gene_synonym="4930544L10Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2218..2223
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Rnf121"
                     /gene_synonym="4930544L10Rik"
                     /note="hexamer: AATAAA"
     polyA_site      2256
                     /gene="Rnf121"
                     /gene_synonym="4930544L10Rik"
                     /note="major polyA site"
ORIGIN      
        1 ggctcgcggg ggaccggggt gggggccggc cgtgaagatg gcggcagtgg tggaggtgga
       61 ggttggagga ggtgctcttg cggaaaggga gctagatgag gttgatatgt cagacctctc
      121 cccagaggag cagtggaggg tcgaacatgc tcgaatgcat gccaaacatc gtggccacga
      181 agccatgcac gctgaaatgg tcctcatcct cattgctacc ttggtggtgg cccagctgct
      241 cctggtacag tggaaacaga ggcatccccg ttcttacaat atggtgaccc tctttcagat
      301 gtgggttgtt cccctctatt tcacagtgaa gctgcattgg tggaggttct tggtgatctg
      361 gatcttcttc tctgctgtca cagcctttgt caccttccga gccacaagga agcctctagt
      421 acagacaacc ccaaggttgg tttataaatg gtttctgctg atctataaaa tcagctatgc
      481 cactggcatt gttggctaca tggctgtcat gtttaccctc tttggtctta acttattatt
      541 caagattaaa ccagaagatg caatggactt tggcatttct cttctcttct atggcctcta
      601 ctatggagtt cttgagcgtg actttgcaga aatgtgtgca gactatatgg catcaaccat
      661 agggttctac agtgagtcgg gcatgcctac caagcacctc tcagacagcg tgtgtgctgt
      721 gtgtgggcag cagatctttg tggatgtcaa tgaagagggc atcatcgaga acacgtacag
      781 gctttcctgc aatcacgtat tccatgaatt ctgtattcga ggctggtgca tcgtgggaaa
      841 gaagcagaca tgtccctact gcaaggagaa ggtggacctg aagaggatgt tcagcaatcc
      901 ctgggaaagg cctcatgtca tgtatggaca gctgctagac tggcttcgat acttggtagc
      961 ctggcagcct gtcatcattg gcctggtaca aggcatcagc tacatcctgg gcctcgagta
     1021 atcagaaatc acatccctgg agaacccacc acccactatg gacctcaggg cactctccgt
     1081 gctgcccaca aagacttggg tggaaaagac tcaaaggcac ttgggccatt caggaccacc
     1141 ccagctgtgt ctgggttggt ggggaaatga tggagaacca gccagtgggg ctgtcagcag
     1201 tgggggcttt ttaaaagaaa attattttga tgaatatatt taaatttttt tattgtggag
     1261 cataggaatt gtcccccatt cctaggccta accttgcttg aacagggttg ggcaaagctg
     1321 cggtattatt ggttgagagg cgtcttctca cctctggctg agagcactgg tgggtttgca
     1381 ggaggctggg tgcttcagcc tacccttccc cttcccctcc cttccctctg caaggctcaa
     1441 gcctggtttg cactcagtgt agaagagctc agacgggtgc cagattagca ctgagcggta
     1501 aagggtctct tcatctctgg acatgatggg tgttgtgtat gactctgttg cctttttgtc
     1561 tggaaactaa aggctggggg tggcaaaatc aatgactttt ctaactaggg aagccctgtg
     1621 gcctccaaat tcactgacat gttttggaac agctagaaat atgagcagca tggataacct
     1681 gcccctgagc agggccattg ccaggcagag tataaaagca atctatatat cattaagctg
     1741 tggaagctac attggcagca gcgaatgttg cagcttcttg tgcaagtaca cccttcatgg
     1801 aagtgttgac atgtgccaaa gggtactctg cacatcactt ccttcctgaa agcctaagag
     1861 tgtgtatgtt tgtgtatgca cagagcagac agactaatgg atctctgttt tctgccagtc
     1921 atcagtgtgc ccttgaagct aagaggggat tccagcccag gaaacgtccc taggtaggct
     1981 tggtcatttg tgggtttttc ccaggcctga cgttaagaat ggtgagtgca taggcagaat
     2041 gaggcctgaa taaagatggg ctctgaaagg ggacttctga gcaggcctaa ctgtagtcct
     2101 ggaagtctga agaaaggggg agggcatcat gggtcagcag cactgggtgt ctagagaaat
     2161 ttggcctggc ccatttgaag gcaacaagaa ccaaacagga tcttgtcatc acatctgaat
     2221 aaagctccat gagctggctg caaagctgga cacgcaaaaa aaaaaaaaaa aa
//
