LOCUS       NM_013876               2132 bp    mRNA    linear   ROD 02-JUN-2024
DEFINITION  Mus musculus ring finger protein 11 (Rnf11), mRNA.
ACCESSION   NM_013876
VERSION     NM_013876.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2132)
  AUTHORS   Massart,J., Sjogren,R.J.O., Egan,B., Garde,C., Lindgren,M., Gu,W.,
            Ferreira,D.M.S., Katayama,M., Ruas,J.L., Barres,R., O'Gorman,D.J.,
            Zierath,J.R. and Krook,A.
  TITLE     Endurance exercise training-responsive miR-19b-3p improves skeletal
            muscle glucose metabolism
  JOURNAL   Nat Commun 12 (1), 5948 (2021)
   PUBMED   34642330
  REMARK    GeneRIF: Endurance exercise training-responsive miR-19b-3p improves
            skeletal muscle glucose metabolism.
            Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2132)
  AUTHORS   Sun,H. and Hunter,T.
  TITLE     Poly-small ubiquitin-like modifier (PolySUMO)-binding proteins
            identified through a string search
  JOURNAL   J Biol Chem 287 (50), 42071-42083 (2012)
   PUBMED   23086935
REFERENCE   3  (bases 1 to 2132)
  AUTHORS   Dalal,N.V., Pranski,E.L., Tansey,M.G., Lah,J.J., Levey,A.I. and
            Betarbet,R.S.
  TITLE     RNF11 modulates microglia activation through NF-kappaB signalling
            cascade
  JOURNAL   Neurosci Lett 528 (2), 174-179 (2012)
   PUBMED   22975135
  REMARK    GeneRIF: Microglial RNF11 is a negative regulator of NF-kappaB
            signalling pathway and could be a strong potential target for
            modulating inflammatory responses in neurodegenerative diseases.
REFERENCE   4  (bases 1 to 2132)
  AUTHORS   Shembade,N., Pujari,R., Harhaj,N.S., Abbott,D.W. and Harhaj,E.W.
  TITLE     The kinase IKKalpha inhibits activation of the transcription factor
            NF-kappaB by phosphorylating the regulatory molecule TAX1BP1
  JOURNAL   Nat Immunol 12 (9), 834-843 (2011)
   PUBMED   21765415
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 2132)
  AUTHORS   Rorick,N.K., Kinoshita,A., Weirather,J.L., Peyrard-Janvid,M., de
            Lima,R.L., Dunnwald,M., Shanske,A.L., Moretti-Ferreira,D.,
            Koillinen,H., Kere,J., Mansilla,M.A., Murray,J.C., Goudy,S.L. and
            Schutte,B.C.
  TITLE     Genomic strategy identifies a missense mutation in WD-repeat domain
            65 (WDR65) in an individual with Van der Woude syndrome
  JOURNAL   Am J Med Genet A 155A (6), 1314-1321 (2011)
   PUBMED   21574244
REFERENCE   6  (bases 1 to 2132)
  AUTHORS   Yokoyama,S., Ito,Y., Ueno-Kudoh,H., Shimizu,H., Uchibe,K.,
            Albini,S., Mitsuoka,K., Miyaki,S., Kiso,M., Nagai,A., Hikata,T.,
            Osada,T., Fukuda,N., Yamashita,S., Harada,D., Mezzano,V., Kasai,M.,
            Puri,P.L., Hayashizaki,Y., Okado,H., Hashimoto,M. and Asahara,H.
  TITLE     A systems approach reveals that the myogenesis genome network is
            regulated by the transcriptional repressor RP58
  JOURNAL   Dev Cell 17 (6), 836-848 (2009)
   PUBMED   20059953
REFERENCE   7  (bases 1 to 2132)
  AUTHORS   Bailey,P.J., Klos,J.M., Andersson,E., Karlen,M., Kallstrom,M.,
            Ponjavic,J., Muhr,J., Lenhard,B., Sandelin,A. and Ericson,J.
  TITLE     A global genomic transcriptional code associated with CNS-expressed
            genes
  JOURNAL   Exp Cell Res 312 (16), 3108-3119 (2006)
   PUBMED   16919269
REFERENCE   8  (bases 1 to 2132)
  AUTHORS   Liu,W., Rui,H., Wang,J., Lin,S., He,Y., Chen,M., Li,Q., Ye,Z.,
            Zhang,S., Chan,S.C., Chen,Y.G., Han,J. and Lin,S.C.
  TITLE     Axin is a scaffold protein in TGF-beta signaling that promotes
            degradation of Smad7 by Arkadia
  JOURNAL   EMBO J 25 (8), 1646-1658 (2006)
   PUBMED   16601693
REFERENCE   9  (bases 1 to 2132)
  AUTHORS   Jolliffe,C.N., Harvey,K.F., Haines,B.P., Parasivam,G. and Kumar,S.
  TITLE     Identification of multiple proteins expressed in murine embryos as
            binding partners for the WW domains of the ubiquitin-protein ligase
            Nedd4
  JOURNAL   Biochem J 351 Pt 3 (Pt 3), 557-565 (2000)
   PUBMED   11042109
REFERENCE   10 (bases 1 to 2132)
  AUTHORS   Seki,N., Hattori,A., Hayashi,A., Kozuma,S., Sasaki,M., Suzuki,Y.,
            Sugano,S., Muramatsu,M.A. and Saito,T.
  TITLE     Cloning and expression profile of mouse and human genes,
            Rnf11/RNF11, encoding a novel RING-H2 finger protein
  JOURNAL   Biochim Biophys Acta 1489 (2-3), 421-427 (1999)
   PUBMED   10673045
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AL669905.14.
            
            [WARNING] On Jul 10, 2024 this sequence was replaced by
            NM_013876.4.
            
            On Mar 21, 2007 this sequence version replaced NM_013876.2.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC010299.1, AK014254.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-396               AL669905.14        135482-135877       c
            397-566             AL669905.14        116270-116439       c
            567-2132            AL669905.14        112229-113794       c
FEATURES             Location/Qualifiers
     source          1..2132
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="4"
                     /map="4 51.29 cM"
     gene            1..2132
                     /gene="Rnf11"
                     /note="ring finger protein 11"
                     /db_xref="GeneID:29864"
                     /db_xref="MGI:MGI:1352759"
     exon            1..396
                     /gene="Rnf11"
                     /inference="alignment:Splign:2.1.0"
     CDS             274..738
                     /gene="Rnf11"
                     /note="sid 1669; NEDD4 WW domain-binding protein 2"
                     /codon_start=1
                     /product="RING finger protein 11"
                     /protein_id="NP_038904.1"
                     /db_xref="CCDS:CCDS18464.1"
                     /db_xref="GeneID:29864"
                     /db_xref="MGI:MGI:1352759"
                     /translation="MGNCLKSPTSDDISLLHESQSDRASFGEGTEPDQEPPPPYQEQV
                     PVPIYHPTPSQTRLATQLTEEEQIRIAQRIGLIQHLPKGVYDPGRDGSEKKIRECVIC
                     MMDFVYGDPIRFLPCMHIYHLDCIDDWLMRSFTCPSCMEPVDAALLSSYETN"
     exon            397..566
                     /gene="Rnf11"
                     /inference="alignment:Splign:2.1.0"
     exon            567..2132
                     /gene="Rnf11"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2001..2006
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Rnf11"
                     /note="hexamer: AGTAAA"
     polyA_site      2027
                     /gene="Rnf11"
                     /note="major polyA site"
     polyA_site      2125
                     /gene="Rnf11"
ORIGIN      
        1 gtggggaagc gctcagtctt cccgcccccg cccccctcag gttccagacg cgaccccggc
       61 gcagcccgcg gcctagcctc gcgccccctg tcccgggggc tggcatgagc ggcccctcgg
      121 tggcgccggg gcgcggggga gccgccgcct gagccccggg cctgccgcct tggaccccgc
      181 ggcgccgagc gagctcaccg ccgagcgtgc gagagaccgg gtcacagctt tcttcctccc
      241 gcagatctca agcatacacc ccagccccgg aagatgggga actgcctcaa atccccgact
      301 tcggatgaca tctccctgct tcacgagtct cagtccgacc gggctagctt tggcgagggg
      361 acggagccag atcaggagcc gccgccgcca tatcaggaac aagttcctgt tcccatctat
      421 catccgacac ctagccagac tcggctagca actcagctga ctgaagagga acaaattaga
      481 atagctcaaa gaataggcct tatacagcat ctgcctaaag gagtttatga ccctggaaga
      541 gatggatcag aaaaaaagat ccgagagtgt gtgatctgta tgatggactt tgtttatggg
      601 gacccaattc gatttctgcc gtgcatgcac atctatcacc tggactgtat agatgactgg
      661 ttgatgagat ccttcacgtg cccctcctgc atggagccag tggatgcagc actgctttca
      721 tcctatgaga ctaattgagc cagggtctct cgtctgactt caagtgaacc atcagttttg
      781 gtggttttga tcttttgtca ctgagcccaa agagccaggg attaggaatt aagatcatgc
      841 acaaaagttt cctaaaaatt cctggatggc tgcagatgtt gagggaagta tgtgatattt
      901 tagaaattta gggggaaagt aggatggatg gtatttttat gtaaagcctt gacccagtgt
      961 ttaaaatata attgttatta gaccttgttc ttgctccagt acataggaat tgtgtaaagt
     1021 gttacagcaa ctgtacatgt ttaaattgtg tgtgttgaag cttaggaaaa agatagttgt
     1081 tatttttcct aaatgaaata agtttcttct cccacccaaa ttcttttctg aaaagttact
     1141 gacatttggg tcaaggtttt attaaaagct acattttata acactggcac aaaaaaaaaa
     1201 aaatagtagt tttaagcttg tttgcacagt tctttttttc cattggaaat ggaattcatt
     1261 gccttaggtc tttttaaata gtgtattatt atcgttgggg ctggctctat gcttgaaaac
     1321 cagtttattt ataacctgtt gtaagtgcta tattctgttt gcagttagga aatgcagaat
     1381 tcacagtgat ctcctagctt gtaagcaaac tgagatgcac tatccctttt ctattaagaa
     1441 tgagttgatg tgtcaggaaa caaggctagc aaagtggatt tgatatccct ttccttgtgt
     1501 gtcttatctt attgttttgg tggttaatat ggtgataatt gaaagtcaag ttgaaattca
     1561 aatattaata tttctgattt gttgagcttt gaattatgcc accatgctta tataaaaacg
     1621 aaggtggcac catgatgaaa cttaaagaaa cagtttctca tctgtaacag ttttgattct
     1681 ctttcctgtg acctctttcc ccactgtctg gaaccatagc aaaaggatac tgcatctctt
     1741 gttactgtag tgctgaggtt attgaagtta cagaaacaca tctggtgtgt ttcctagaaa
     1801 agtacctgtt cagtcttgct aggtgactga caggagaggc aaatgtgtta tgttttgcac
     1861 accaatgcag cagggtttgt ataaccacat gacttcatag ttgtgatctc aaaggaactt
     1921 ctcctttatt ttttcttgca attaatgtaa gaatactcta aatctctgca cttctgaagg
     1981 attagaggta gaaatggtct agtaaagtgt aatgttttat tcatttagca tgtgtttatt
     2041 ttccttatgt tctccaggtg attcgttcct tccactcagt gatattgtgg ttaaaaaatg
     2101 atgagcagaa gcgctctcca ccttacaaat ga
//
