LOCUS       NM_173742                622 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus ribonuclease, RNase K (Rnasek), mRNA.
ACCESSION   NM_173742
VERSION     NM_173742.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 622)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 622)
  AUTHORS   Ingham,N.J., Pearson,S.A., Vancollie,V.E., Rook,V., Lewis,M.A.,
            Chen,J., Buniello,A., Martelletti,E., Preite,L., Lam,C.C.,
            Weiss,F.D., Powis,Z., Suwannarat,P., Lelliott,C.J., Dawson,S.J.,
            White,J.K. and Steel,K.P.
  TITLE     Mouse screen reveals multiple new genes underlying mouse and human
            hearing loss
  JOURNAL   PLoS Biol 17 (4), e3000194 (2019)
   PUBMED   30973865
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 622)
  AUTHORS   Hald,J., Galbo,T., Rescan,C., Radzikowski,L., Sprinkel,A.E.,
            Heimberg,H., Ahnfelt-Ronne,J., Jensen,J., Scharfmann,R.,
            Gradwohl,G., Kaestner,K.H., Stoeckert,C. Jr., Jensen,J.N. and
            Madsen,O.D.
  TITLE     Pancreatic islet and progenitor cell surface markers with cell
            sorting potential
  JOURNAL   Diabetologia 55 (1), 154-165 (2012)
   PUBMED   21947380
REFERENCE   4  (bases 1 to 622)
  AUTHORS   Hoffman,B.G., Zavaglia,B., Witzsche,J., Ruiz de Algara,T.,
            Beach,M., Hoodless,P.A., Jones,S.J., Marra,M.A. and Helgason,C.D.
  TITLE     Identification of transcripts with enriched expression in the
            developing and adult pancreas
  JOURNAL   Genome Biol 9 (6), R99 (2008)
   PUBMED   18554416
REFERENCE   5  (bases 1 to 622)
  AUTHORS   Blackshaw,S., Harpavat,S., Trimarchi,J., Cai,L., Huang,H.,
            Kuo,W.P., Weber,G., Lee,K., Fraioli,R.E., Cho,S.H., Yung,R.,
            Asch,E., Ohno-Machado,L., Wong,W.H. and Cepko,C.L.
  TITLE     Genomic analysis of mouse retinal development
  JOURNAL   PLoS Biol 2 (9), E247 (2004)
   PUBMED   15226823
REFERENCE   6  (bases 1 to 622)
  AUTHORS   Brady,K.P., Rowe,L.B., Her,H., Stevens,T.J., Eppig,J.,
            Sussman,D.J., Sikela,J. and Beier,D.R.
  TITLE     Genetic mapping of 262 loci derived from expressed sequences in a
            murine interspecific cross using single-strand conformational
            polymorphism analysis
  JOURNAL   Genome Res 7 (11), 1085-1093 (1997)
   PUBMED   9371744
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            CJ181610.1, AK009592.1 and BB308989.1.
            
            On Apr 20, 2010 this sequence version replaced NM_173742.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: CJ181610.1, CB598305.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849384, SAMN01164131
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-6                 CJ181610.1         1-6
            7-612               AK009592.1         2-607
            613-622             BB308989.1         269-278
FEATURES             Location/Qualifiers
     source          1..622
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="11"
                     /map="11 42.99 cM"
     gene            1..622
                     /gene="Rnasek"
                     /gene_synonym="2310033H11Rik; D11Bwg0434e"
                     /note="ribonuclease, RNase K"
                     /db_xref="GeneID:52898"
                     /db_xref="MGI:MGI:106369"
     exon            1..197
                     /gene="Rnasek"
                     /gene_synonym="2310033H11Rik; D11Bwg0434e"
                     /inference="alignment:Splign:2.1.0"
     exon            198..274
                     /gene="Rnasek"
                     /gene_synonym="2310033H11Rik; D11Bwg0434e"
                     /inference="alignment:Splign:2.1.0"
     exon            275..622
                     /gene="Rnasek"
                     /gene_synonym="2310033H11Rik; D11Bwg0434e"
                     /inference="alignment:Splign:2.1.0"
     regulatory      597..602
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Rnasek"
                     /gene_synonym="2310033H11Rik; D11Bwg0434e"
                     /note="hexamer: AATAAA"
     polyA_site      621
                     /gene="Rnasek"
                     /gene_synonym="2310033H11Rik; D11Bwg0434e"
                     /note="major polyA site"
ORIGIN      
        1 gtcgctctgc gccgcgcaag tccccaaatc cagctcctgt cctagcattt ccagggttcc
       61 ctctcccggc ttctgtgctc cgctcagtct ccagcgatcc ctccctacct ccgccctcca
      121 tggcgtcgct cctgtgctgt gggcctaagc tggccgcctg tggcatcgtc ctcagcgcct
      181 ggggagtgat catgttgata atgctcggga tatttttcaa tgtccattct gctgtgttaa
      241 ttgaggacgt tcccttcaca gagaaagatt ttgagaacgg tcctcagaac atatacaacc
      301 tgtacgagca agtcagctac aactgtttca tcgccgcggg cctctacctc ctcctcggag
      361 gcttctcctt ctgccaagtt cgtctcaaca agcgcaagga atacatggtg cgctagagcg
      421 cggtccgcct ctccctcccc agcccccttc tctatttaaa gactccgcag actccgtccc
      481 actcatctgg cgtcctttgg gacttgtgac cctagcgaga cgtcatccct ggccctgcaa
      541 aactgcgccc agcctctgga ggagaccgag ggtgaccgcg ccccgttctg aactacaata
      601 aaaagaagcg gttcccccta ag
//
