LOCUS       NM_024288               6165 bp    mRNA    linear   ROD 05-AUG-2023
DEFINITION  Mus musculus required for meiotic nuclear division 5 homolog A
            (Rmnd5a), transcript variant 1, mRNA.
ACCESSION   NM_024288 XM_909570 XM_921359
VERSION     NM_024288.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 6165)
  AUTHORS   Carrier A, Nguyen C, Victorero G, Granjeaud S, Rocha D, Bernard K,
            Miazek A, Ferrier P, Malissen M, Naquet P, Malissen B and Jordan
            BR.
  TITLE     Differential gene expression in CD3epsilon- and RAG1-deficient
            thymuses: definition of a set of genes potentially involved in
            thymocyte maturation
  JOURNAL   Immunogenetics 50 (5-6), 255-270 (1999)
   PUBMED   10630289
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK164384.1, CF748545.1, AK148556.1 and AC160090.4.
            
            [WARNING] On Jan 16, 2024 this sequence was replaced by
            NM_024288.3.
            
            On Nov 13, 2009 this sequence version replaced NM_024288.1.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC050876.1, SRR1660819.88649.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164131, SAMN01164139
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-326               AK164384.1         2-327
            327-991             CF748545.1         1-665
            992-2141            AK148556.1         227-1376
            2142-6165           AC160090.4         3119-7142
FEATURES             Location/Qualifiers
     source          1..6165
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="6"
                     /map="6 32.14 cM"
     gene            1..6165
                     /gene="Rmnd5a"
                     /gene_synonym="1110007A06Rik; Gid2; MTA.D02.090"
                     /note="required for meiotic nuclear division 5 homolog A"
                     /db_xref="GeneID:68477"
                     /db_xref="MGI:MGI:1915727"
     exon            1..640
                     /gene="Rmnd5a"
                     /gene_synonym="1110007A06Rik; Gid2; MTA.D02.090"
                     /inference="alignment:Splign:2.1.0"
     CDS             499..1674
                     /gene="Rmnd5a"
                     /gene_synonym="1110007A06Rik; Gid2; MTA.D02.090"
                     /EC_number="2.3.2.27"
                     /note="protein RMD5 homolog A"
                     /codon_start=1
                     /product="E3 ubiquitin-protein ligase RMND5A"
                     /protein_id="NP_077250.2"
                     /db_xref="CCDS:CCDS20231.1"
                     /db_xref="GeneID:68477"
                     /db_xref="MGI:MGI:1915727"
                     /translation="MDQCVTVERELEKVLHKFSGYGQLCERGLEELIDYTGGLKHEIL
                     QSHGQDAELSGTLSLVLTQCCKRIKDTVQKLASDHKDIHSSVSRVGKAIDKNFDSDIS
                     SVGIDGCWQADSQRLLNEVMVEHFFRQGMLDVAEELCQESGLSVDPSQKEPFVELNRI
                     LEALKVRVLRPALEWAVSNREMLIAQNSSLEFKLHRLYFISLLMGGTTNQREALQYAK
                     NFQPFALNHQKDIQVLMGSLVYLRQGIENSPYVHLLDANQWADICDIFTRDACALLGL
                     SVESPLSVSFSAGCVALPALINIKAVIEQRQCTGVWNQKDELPIEVDLGKKCWYHSIF
                     ACPILRQQTTDNNPPMKLVCGHIISRDALNKMFNGSKLKCPYCPMEQSPGDAKQIFF"
     exon            641..783
                     /gene="Rmnd5a"
                     /gene_synonym="1110007A06Rik; Gid2; MTA.D02.090"
                     /inference="alignment:Splign:2.1.0"
     exon            784..918
                     /gene="Rmnd5a"
                     /gene_synonym="1110007A06Rik; Gid2; MTA.D02.090"
                     /inference="alignment:Splign:2.1.0"
     exon            919..1019
                     /gene="Rmnd5a"
                     /gene_synonym="1110007A06Rik; Gid2; MTA.D02.090"
                     /inference="alignment:Splign:2.1.0"
     exon            1020..1186
                     /gene="Rmnd5a"
                     /gene_synonym="1110007A06Rik; Gid2; MTA.D02.090"
                     /inference="alignment:Splign:2.1.0"
     exon            1187..1352
                     /gene="Rmnd5a"
                     /gene_synonym="1110007A06Rik; Gid2; MTA.D02.090"
                     /inference="alignment:Splign:2.1.0"
     exon            1353..1455
                     /gene="Rmnd5a"
                     /gene_synonym="1110007A06Rik; Gid2; MTA.D02.090"
                     /inference="alignment:Splign:2.1.0"
     exon            1456..1610
                     /gene="Rmnd5a"
                     /gene_synonym="1110007A06Rik; Gid2; MTA.D02.090"
                     /inference="alignment:Splign:2.1.0"
     exon            1611..6165
                     /gene="Rmnd5a"
                     /gene_synonym="1110007A06Rik; Gid2; MTA.D02.090"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 accttcagaa cgcccgcgcg ccctccgccc gtgctcgccc gctgcttccc cctgacccct
       61 cgccgagtcc gcgattggta cggcccgcgc cgcctcctcc gctcgtgagg gaggctcgac
      121 cccctcccgg gccgcggcta ttggtgccgc ccgggagaac caggtcatcg gccggttccc
      181 gtgaaaacaa aaacaatcgg cggcgccgcc gaggggcggc cgaacgcggc gagccagggg
      241 ggcccggggc gagacgcggc gccgggtagg gcgggcgagc gagcgcgagc ggcggggccg
      301 gggcgccatg gggcgggagg gcacaggctg cgcggggctc ccccggcgcc gcggctagcg
      361 cgcccgtctt gccttcgcct cccgcgccgc ccgctcgccg ccttggggga ggaggagcag
      421 gacgcggcct cggtggggcc cgggccgaac cactgcggac ccccgggcgc cggggagccg
      481 agcgccgcgg tctccggcat ggatcagtgc gtgacggtgg agcgcgagct ggagaaggtg
      541 ctgcacaagt tctcgggcta cgggcagctg tgcgagcggg gcctggagga gctcatcgac
      601 tacaccggcg gcctcaagca cgagatcctg cagagccacg gtcaagatgc tgaattatca
      661 gggacacttt cacttgttct gacacagtgc tgcaaaagaa taaaggacac tgtccagaag
      721 ttggcctctg accacaaaga catccatagc agtgtttctc gagttggaaa agccattgat
      781 aagaattttg attctgacat tagcagtgtg ggaatagatg gctgctggca ggcagacagc
      841 caacggcttc tcaatgaggt catggtggaa cacttcttcc gacaaggaat gctggatgta
      901 gctgaggagc tttgccagga atctggtctg tctgtagacc caagtcagaa agaaccattt
      961 gtggagttaa atagaatatt agaagcatta aaagtcagag ttctaaggcc tgctctcgag
     1021 tgggcagtat caaaccgaga aatgctcata gcccaaaaca gttccttgga atttaagcta
     1081 caccgactgt attttattag cttgttaatg ggtggaacta caaatcagcg agaagcctta
     1141 caatatgcga aaaatttcca gccatttgcc ctaaatcatc aaaaagacat tcaggtattg
     1201 atgggaagcc tcgtgtacct gcgacaaggg attgaaaact caccatatgt tcacttactt
     1261 gatgcaaacc agtgggctga catctgtgac atctttacac gggatgcttg tgccctcctg
     1321 gggctctccg tggagtctcc tctcagtgtc agtttctcag caggttgtgt ggcgctgcct
     1381 gcgctaatta acatcaaagc tgtgattgag cagaggcagt gtactggagt ttggaaccag
     1441 aaagacgaat tacctattga agtggacctt ggtaaaaagt gctggtatca ctccatattt
     1501 gcctgtccca ttcttcgtca gcaaacaaca gataacaatc cacccatgaa attggtttgt
     1561 ggtcatatta tatcaagaga cgccctgaat aaaatgttta atggtagcaa attaaaatgt
     1621 ccatattgcc caatggaaca gagtccagga gatgccaaac agatattttt ctgaagaatg
     1681 agtttgtttg caatttgtaa gtgaaactga attatgggta cattcaagac aagagtgttc
     1741 cattgactgc agctatccaa ggaccgcctg ttcataagct atgctccaga ggctgccgat
     1801 tcactcgtgt gcacggaggg ggtgctccag atgggaatca cacagggctt tcttcactct
     1861 tggtcttcgt ttctgatcaa gtaaacacca gcagttgtca ttcagtgcag gtttttgtac
     1921 ttctatatgg tgattttttt acttaaaagc agaaacagaa gttgaccttc ctgacatgtg
     1981 tttaatattc ctcctgcttt tacagattct gacgttttct tgataattgt aagcttgaga
     2041 gtgtttgtgg aagaacttac tttcttctta tgtatacata attaaatgaa aagtcttcat
     2101 aggagtttga caaaatgaat tgtggttata aaacgaattt gcttttttgt tgttttgttt
     2161 ttcttttttg gcctaaggaa gaaagctgtg ataaatttca aatttgcata gcttttcaat
     2221 gttttgctct gctcccgctc ttgcttcaga gtcggcacac tcacctgcat ttgagttctg
     2281 tctatagccc agcaggctgc ctgtttaaaa tcccatcatg aatttaacag gctgatgtga
     2341 gaatgaaata gatattactg gggttttgtt gttgtttgtt tatttgtttt gcttttatta
     2401 ccaagaggtg ctttttaata aatggatatt gaagttaggg tgttactaat ttgatgtatg
     2461 gtttcacagt ctagcatact gtcctttgac atctgccttt aagacttggc tgagtgtctc
     2521 attagtttat catcacagat acgcagtgtt atgcatgtgt atagaagtgt gtgcaccagc
     2581 atcaaacatt gtgtgtgtgg aagggaagaa gcctgtccat tctaaacgca gttgccagtc
     2641 tcatcacttc aggtccttac gggcaggctc tagcaacttt ccgtgtatgg acctcgtttt
     2701 ttgctgtttt gtgtttaatt agtatattgt tcatgcctct cttctgcagt gtctcatctc
     2761 atagactgtg aacctgtata ttattcaaat ggctacagat aatgctcttt tcttttgtga
     2821 ggtctcttca tttaatgcac tgcccagaaa gagccatgtg taagagttgt tctctgtttg
     2881 aggaactaac tacatggaaa agacttctga cttaaaccca tgaaatactt catcttgaga
     2941 agagtgctat gtggaaatca ccaaatatct cgcaacttta tttcatctgg tgtaaatctg
     3001 aacatcaaca taggaaaact gtcatgagaa aatgaaaaag cataaacaca gaagcaacga
     3061 gaaatgtgac tcttgttatt ttaaaccaca gacggacttg ggttaaggga atggggacga
     3121 cagctttggt gctaagttaa tcagaaattg cgagcatgca cagtggtatg ccagcctggg
     3181 tgatgctttc ctaggagagc cggtatttgc ttgtaaggga aagaatggta ttgtagaaaa
     3241 acccaagaaa tgaccacgtg gtcagtttca tggtgatggc tactgtgtac tgtgtaggtt
     3301 acctgggtca agactggtcc agcttagagt gcatgctctg ttcatactca gcctagctca
     3361 cagtgacttg tgcttcactg tcaggatgct ctgtaaagtt cctcatccct gtgaagcagg
     3421 gaaagaacag aggtgcctct ggactgcagg agaaaggcgt cgtgccaggc agtatcctgt
     3481 ggagggagga gggtgtacgt tcgtttacta tggatagttt ttcctttgaa ttaaattgta
     3541 gcgtgtcagg ctttcttttt tcttttcttt tccttttttt aaactttgtt attcctaagc
     3601 caaatttagt ttttaggttt ctttttttct ctataactta ttcttgcctt cccacctcaa
     3661 gcgtctgtat aacatttaga ctacacataa agtttatgtg gtacagacat gcccttgagg
     3721 ttggtggaaa ataaaaaaca agacccttca cacagttagc tcaggccatt ttaaggacga
     3781 aggctctgct ggtcctcctg tgctgggaat ctctttgatg gcctcttgtg aagctcatga
     3841 aactttaaca agtgtttgac cttacagctt cctctgggag gtcgtgtaga cccagtgggc
     3901 aagcaggaca agggcccaga actgaaactt gatcttaaaa tttaccatgg aaatgaggtc
     3961 ttaggctctt ctttaaatgt gtgtactttt atctgtgaga gactgactat agcagaagcg
     4021 gattcaaaga agacagacct tgaccaaaga tgctgaaata cagtgttggg atccttgtac
     4081 tctggaacca tgccatcact gatgtcatgc tcatgctacc tagcatgcag gaggatgcca
     4141 tctgtttctt tgagccttgt tagagaaggt aatgctagag gaagactcag tcacacagat
     4201 aacaggcatt ggaaacagcc gcactatggc ttctttgaga ccctatttcc ttttctggtt
     4261 gtggacaagg ctgccttagg actttgctaa cccaataaaa cctttagatt ctggtgaagc
     4321 cagagcctct ccacagtggc taaggttgtt gttgatcttt ttctcctttg tgtgatcatc
     4381 acagatgcca tttctgtttt attgatgatt atatgagact tttaatacat aaatgaacgg
     4441 gtactggtgc ctctttattt ttaaaaattt gaagaaaaag agccacctca tattcataga
     4501 gtgtgtattt tgtgagtgtg tgagcatttg attggaaata agaaagttat taagtaaatt
     4561 tttcgtttta ctttttccac agcagctaac gtgtagggag acattaaacc cacaccaaat
     4621 catgaggggc tgaggacccc caatcttctt ctctaggtcg ccaatcccac aggctgtaca
     4681 gctcagttcc ctatgtttat gctgtgttgt tcccacctca gtgctgtcag cctttgggac
     4741 agtggctctc aaaagccaag agctcttggt ttatctgcac agtacaagct gctggtagac
     4801 tacactagcc ctctggtttc ccagcgcagc ctctcataca gtggactgac agcctgcact
     4861 ctgtttagtc agccgactca ggttatcttc agggaaggta tggaggcatg gtttgtttcg
     4921 gttcatctcc aggatgtata cagtgaagac aaaccaaata cttttcacca ttgaactatc
     4981 tgtacattat ctttggtaac actagactag tgtagtcttg gggaacacac cgaggaaaca
     5041 tgtagcgaga atcacataca aggcttggtg tttcataagc atgcctgctg acagctgtat
     5101 gtggtactgc agtgtttacc ataaacaggt acaggcttca tgagtttttc atactgattt
     5161 acaattgagt agataccaaa aacagagtgg caagtgtatt ttagtagcag ttgaggcaat
     5221 tagttttagg gtgaattttt cactgttgat tttactttaa gatgtagcca gagaaagttt
     5281 tgtttttaag gcattttaaa gctgtagcag gcgtatgctt cattttcttc caaagaggca
     5341 aaagcagcta gactcgctta cagcacatgc ttcgctccat ggtatgggtg gacacctaca
     5401 cttgtcagta gcagtcttaa actcctcact gccaggcagg ggtgggcttc tgtaggattt
     5461 agtgcctgaa catttctttt ggaaggggct ggagtgaatg tactgggtat gggaggggag
     5521 cagaaggaaa taggactgtg agtgagtgtg catgtgtggg aattcatcat aacccttgaa
     5581 gctagcaagc gaccgctgtt ggccgagctt cactcatgac tgcagcgtgc atgtatctct
     5641 tcaccatgtc ttctctcacc ttcactaagg agtcaccaga tcatctggct cagatgctca
     5701 ggatgtattc ctttggctta ccccgtgctc ctgggttcta tggtgtttct ataattatga
     5761 atagtgttgc actgtaatct atcatataga gctatatgta tggaaatttt tgatcagttt
     5821 tttaagagat gtatcctgtt tgcaaaggca caataaaatt gcatcttcta gattataggc
     5881 aataaagata acaataaacc ttatttaaca aatcagactg atactctctg cttatttgat
     5941 ttggtggggg agggaggatg tctaacatat ccagtagttt cagggatttc attttaactt
     6001 aaaaactctg atatatttaa tttataaatt tcggactgat aaaaaaatag agttttggaa
     6061 aactataaaa aatgctttgt taatgtgtgt attcctatgt aaaacacatg gcttcttctg
     6121 tgtatatttt ttaaaattaa agacttgcac atttaaaaaa ctgtt
//
