LOCUS       NM_001414407            2625 bp    mRNA    linear   ROD 14-JUN-2024
DEFINITION  Mus musculus regulator of microtubule dynamics 2 (Rmdn2),
            transcript variant 14, mRNA.
ACCESSION   NM_001414407 XM_006524495
VERSION     NM_001414407.1
KEYWORDS    RefSeq.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2625)
  AUTHORS   Gineste,C., De Winter,J.M., Kohl,C., Witt,C.C., Giannesini,B.,
            Brohm,K., Le Fur,Y., Gretz,N., Vilmen,C., Pecchi,E., Jubeau,M.,
            Cozzone,P.J., Stienen,G.J., Granzier,H., Labeit,S.,
            Ottenheijm,C.A., Bendahan,D. and Gondin,J.
  TITLE     In vivo and in vitro investigations of heterozygous nebulin
            knock-out mice disclose a mild skeletal muscle phenotype
  JOURNAL   Neuromuscul Disord 23 (4), 357-369 (2013)
   PUBMED   23375831
REFERENCE   2  (bases 1 to 2625)
  AUTHORS   Oishi,K., Okano,H. and Sawa,H.
  TITLE     RMD-1, a novel microtubule-associated protein, functions in
            chromosome segregation in Caenorhabditis elegans
  JOURNAL   J Cell Biol 179 (6), 1149-1162 (2007)
   PUBMED   18070910
  REMARK    Erratum:[J Cell Biol. 2009 Aug 24;186(4):629]
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC132612.3.
            
            On Nov 23, 2022 this sequence version replaced XM_006524495.3.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR17784647.242803.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849381, SAMN01164131
                                           [ECO:0000348]
            ##Evidence-Data-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-152               AC132612.3         90463-90614
            153-619             AC132612.3         96552-97018
            620-1537            AC132612.3         102708-103625
            1538-1712           AC132612.3         125548-125722
            1713-1815           AC132612.3         126945-127047
            1816-1876           AC132612.3         134659-134719
            1877-1952           AC132612.3         142117-142192
            1953-2030           AC132612.3         143197-143274
            2031-2129           AC132612.3         145803-145901
            2130-2183           AC132612.3         147596-147649
            2184-2264           AC132612.3         147739-147819
            2265-2314           AC132612.3         156879-156928
            2315-2625           AC132612.3         159912-160222
FEATURES             Location/Qualifiers
     source          1..2625
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="17"
                     /map="17 50.3 cM"
     gene            1..2625
                     /gene="Rmdn2"
                     /gene_synonym="Fam82a1; mRMD-2; RMD-2"
                     /note="regulator of microtubule dynamics 2"
                     /db_xref="GeneID:381110"
                     /db_xref="MGI:MGI:2147043"
     exon            1..152
                     /gene="Rmdn2"
                     /gene_synonym="Fam82a1; mRMD-2; RMD-2"
                     /inference="alignment:Splign:2.1.0"
     exon            153..619
                     /gene="Rmdn2"
                     /gene_synonym="Fam82a1; mRMD-2; RMD-2"
                     /inference="alignment:Splign:2.1.0"
     CDS             168..2342
                     /gene="Rmdn2"
                     /gene_synonym="Fam82a1; mRMD-2; RMD-2"
                     /note="isoform 7 is encoded by transcript variant 14;
                     regulator of microtubule dynamics protein 2;
                     microtubule-associated protein; family with sequence
                     similarity 82, member A1"
                     /codon_start=1
                     /product="regulator of microtubule dynamics protein 2
                     isoform 7"
                     /protein_id="NP_001401336.1"
                     /db_xref="GeneID:381110"
                     /db_xref="MGI:MGI:2147043"
                     /translation="MPHSTNKELILGIMAGTAGISLLAFWYHKVLKPRTTMNFPKLLS
                     LGKKFGSLTLPEESHSAQGASVVFQRRQLQILEKLNELLTNMEELKEEIRFLKETIPK
                     LEECIQDEFGGKVTVHKISPQHRARKKKGTTVQRSATSNSSEEAESEGGCWKKDQCFQ
                     PNHDDPVTPQRMHHGSSRALQTKVALGLITCRPSSTYKIGRKSSSSSSSTTHLCPCKG
                     RHSLLRRFRKRKQQGSRVNFDSQEDLTSSAANSSDQFTLRKSRKYFSSRKLSVVSCHR
                     NSVTYETPRGSLSHENEIQGFSKKSTSTDAPKRISFSDPEHGDRYFANLETKPGSSGH
                     WSFERTPYPLTLTTSLFSLPTVISSSSQVNVSGADNQEHGQLNKVSEDALHHRSQSLS
                     GNYSPAGLEQHPSSASFLQDELSSLYQTIGSLTVEVTSGSFEEESFATPSLDEDIPSP
                     IETDEIRYITANTDTEEQNFPFPKALNTHIEELKLDVLLQKADHLRTNESHKMESFEL
                     LCDHKEKFSEETEFLWRLARAYGDMYDLSTSTQEKKHYANIGKTLGERAITRAPMNGH
                     CHLWYAVLCGYVSEFEGLQNKINCGHLFKKHLEIAIQLLPEEPLLYYLKGRYCYTVSR
                     LSWIEKKMAATLFGEIPYSTVHEALHNFLKTEELQPGYSMSNYMYTAKCYVELGEPQE
                     ACKFCNLALLLPVVTKEDKDAHKEVKKMISSLKRKFHTSSSV"
     exon            620..1537
                     /gene="Rmdn2"
                     /gene_synonym="Fam82a1; mRMD-2; RMD-2"
                     /inference="alignment:Splign:2.1.0"
     exon            1538..1712
                     /gene="Rmdn2"
                     /gene_synonym="Fam82a1; mRMD-2; RMD-2"
                     /inference="alignment:Splign:2.1.0"
     exon            1713..1815
                     /gene="Rmdn2"
                     /gene_synonym="Fam82a1; mRMD-2; RMD-2"
                     /inference="alignment:Splign:2.1.0"
     exon            1816..1876
                     /gene="Rmdn2"
                     /gene_synonym="Fam82a1; mRMD-2; RMD-2"
                     /inference="alignment:Splign:2.1.0"
     exon            1877..1952
                     /gene="Rmdn2"
                     /gene_synonym="Fam82a1; mRMD-2; RMD-2"
                     /inference="alignment:Splign:2.1.0"
     exon            1953..2030
                     /gene="Rmdn2"
                     /gene_synonym="Fam82a1; mRMD-2; RMD-2"
                     /inference="alignment:Splign:2.1.0"
     exon            2031..2129
                     /gene="Rmdn2"
                     /gene_synonym="Fam82a1; mRMD-2; RMD-2"
                     /inference="alignment:Splign:2.1.0"
     exon            2130..2183
                     /gene="Rmdn2"
                     /gene_synonym="Fam82a1; mRMD-2; RMD-2"
                     /inference="alignment:Splign:2.1.0"
     exon            2184..2264
                     /gene="Rmdn2"
                     /gene_synonym="Fam82a1; mRMD-2; RMD-2"
                     /inference="alignment:Splign:2.1.0"
     exon            2265..2314
                     /gene="Rmdn2"
                     /gene_synonym="Fam82a1; mRMD-2; RMD-2"
                     /inference="alignment:Splign:2.1.0"
     exon            2315..2625
                     /gene="Rmdn2"
                     /gene_synonym="Fam82a1; mRMD-2; RMD-2"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2600..2605
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Rmdn2"
                     /gene_synonym="Fam82a1; mRMD-2; RMD-2"
                     /note="hexamer: AATAAA"
     polyA_site      2625
                     /gene="Rmdn2"
                     /gene_synonym="Fam82a1; mRMD-2; RMD-2"
                     /note="major polyA site"
ORIGIN      
        1 atctgggtca gacacgaagg ccaccacgca ggaccttggg acccgcaggc tgcacagggt
       61 tccactcggc catcctctcc tggctcgccc gctcgcccgc gggtcccggt tccctggctc
      121 cagccccaga gaagcctgcg caacgactcc ggaaataaaa gcccagaatg ccccattcca
      181 caaacaaaga gctaatcctt ggcatcatgg cggggactgc tgggatcagc ttgctggcct
      241 tctggtacca caaggtcctc aagccaagga cgaccatgaa cttccctaag cttctttctc
      301 tgggtaagaa atttggttca ctaactctgc cagaggaaag ccacagtgcg caaggagcat
      361 cggtggtctt tcaaaggagg caactccaga tcctggaaaa gctaaacgag ctactgacca
      421 acatggaaga actgaaggag gaaatcagat tccttaaaga gacaattcca aagctggagg
      481 aatgtataca agatgaattc ggagggaagg tgacagttca taagatcagt cctcagcaca
      541 gagcgagaaa aaagaagggg acaaccgttc aacgctcagc aacaagtaac agctcagagg
      601 aggcagaaag tgaagggggc tgctggaaaa aggaccagtg cttccaacca aatcatgacg
      661 atccagttac tccacaacgc atgcatcatg gatcctctcg tgcgttacaa acaaaagtgg
      721 ctctgggtct tataacatgt cgtccttctt caacatataa gataggtaga aaatcctcgt
      781 cctcctcaag ttcaactaca cacttatgtc cgtgtaaagg aagacatagt ttactgcgga
      841 gattccgaaa gaggaaacaa cagggaagta gagttaactt tgattctcag gaagacttaa
      901 cctccagtgc cgcgaattct tcagatcagt tcactttgcg taaatctcga aaatattttt
      961 cttcccgcaa gctgagtgta gtttcctgcc acaggaatag cgttacctat gaaactccac
     1021 gaggtagtct gtctcatgaa aacgaaattc aaggcttttc taaaaagtca actagcacag
     1081 atgctccaaa acgaataagc ttctctgatc ccgaacatgg cgatagatac tttgcaaatc
     1141 tggaaacaaa acccggttct tcaggccact ggagttttga gagaacgcct tacccactaa
     1201 ctctaacaac gtctctcttc tctcttccga ctgttatttc ttcttccagt caagtaaatg
     1261 tgtctggtgc tgataaccaa gagcatggcc agctaaataa ggtttcggag gatgcccttc
     1321 atcacaggtc tcagagtctg agtggaaatt actctccagc tggtttggaa cagcatccgt
     1381 cttctgccag cttcctccaa gatgaacttt cttcactgta ccaaactatc ggtagcttga
     1441 ctgttgaagt tacctcaggc tcctttgaag aagaaagctt tgccacccca tctctagatg
     1501 aagatatacc ttcacctatt gaaacggatg aaataaggta tattacagct aacacggaca
     1561 cagaagaaca gaacttcccg ttccccaagg ctcttaacac acacatagag gagctaaagt
     1621 tggatgtcct ccttcagaag gcagaccatt tgcggacaaa tgagtctcac aaaatggaga
     1681 gttttgagct actctgtgac cacaaggaga agtttagtga agaaactgag tttctgtggc
     1741 gcctggcccg agcctatgga gacatgtatg atctatccac aagtacacaa gaaaagaagc
     1801 attatgctaa tattggaaaa actttaggag agagagctat taccagagcg cccatgaatg
     1861 gacactgcca tctgtggtat gcagttttgt gtggttatgt atctgagttt gagggcttgc
     1921 aaaacaaaat taactgtgga catctattca agaagcatct agaaatagcc atccagcttt
     1981 tgcctgaaga acccttatta tattacctca agggaaggta ctgttataca gtctcaagac
     2041 tcagctggat tgagaaaaaa atggctgcta ctctgttcgg agaaatacca tattcaacgg
     2101 ttcatgaagc tttgcacaac ttccttaaga ctgaagaact gcaacctggt tattccatgt
     2161 ccaactatat gtatacagcc aagtgttatg ttgaacttgg ggaacctcag gaggcttgta
     2221 aattctgtaa cttggcattg ctactgcctg ttgtcaccaa agaggacaag gatgcccata
     2281 aagaggtgaa gaaaatgatc agttctttga agaggaaatt ccatacaagt tcttctgtgt
     2341 gaatactaat ttcctgcggt tgcttcactc accattcaag atacctgacc ttggaaaaaa
     2401 cagatcatgg tcagcatgca ggtgttgagt ccagactaac aggacccctt ccacgtaaag
     2461 atgaaggaca cagagtctga cttttcagga gacttcgtgt acaatgctgg accaagggag
     2521 ttctaatcca gaacttggag tctctcccga agatacaaat caagactgta tgttacaatt
     2581 tctcataaca catgagagaa ataaacacag tgttctgaca tctta
//
