LOCUS       NM_001081241            4152 bp    mRNA    linear   ROD 02-JUN-2024
DEFINITION  Mus musculus RHO family interacting cell polarization regulator 1
            (Ripor1), mRNA.
ACCESSION   NM_001081241 NM_029386 XM_486159
VERSION     NM_001081241.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 4152)
  AUTHORS   Patrakka,J., Xiao,Z., Nukui,M., Takemoto,M., He,L., Oddsson,A.,
            Perisic,L., Kaukinen,A., Szigyarto,C.A., Uhlen,M., Jalanko,H.,
            Betsholtz,C. and Tryggvason,K.
  TITLE     Expression and subcellular distribution of novel
            glomerulus-associated proteins dendrin, ehd3, sh2d4a, plekhh2, and
            2310066E14Rik
  JOURNAL   J Am Soc Nephrol 18 (3), 689-697 (2007)
   PUBMED   17251388
REFERENCE   2  (bases 1 to 4152)
  AUTHORS   Keegan,C.E., Hutz,J.E., Else,T., Adamska,M., Shah,S.P., Kent,A.E.,
            Howes,J.M., Beamer,W.G. and Hammer,G.D.
  TITLE     Urogenital and caudal dysgenesis in adrenocortical dysplasia (acd)
            mice is caused by a splicing mutation in a novel telomeric
            regulator
  JOURNAL   Hum Mol Genet 14 (1), 113-123 (2005)
   PUBMED   15537664
REFERENCE   3  (bases 1 to 4152)
  AUTHORS   Kaelin,C.B., Xu,A.W., Lu,X.Y. and Barsh,G.S.
  TITLE     Transcriptional regulation of agouti-related protein (Agrp) in
            transgenic mice
  JOURNAL   Endocrinology 145 (12), 5798-5806 (2004)
   PUBMED   15345681
REFERENCE   4  (bases 1 to 4152)
  AUTHORS   Okazaki,N., Kikuno,R., Ohara,R., Inamoto,S., Aizawa,H., Yuasa,S.,
            Nakajima,D., Nagase,T., Ohara,O. and Koga,H.
  TITLE     Prediction of the coding sequences of mouse homologues of KIAA
            gene: II. The complete nucleotide sequences of 400 mouse
            KIAA-homologous cDNAs identified by screening of terminal sequences
            of cDNA clones randomly sampled from size-fractionated libraries
  JOURNAL   DNA Res 10 (1), 35-48 (2003)
   PUBMED   12693553
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BB852730.1, AK122573.1 and BC079880.1.
            
            On or before Apr 17, 2007 this sequence version replaced
            NM_029386.2, NM_001081241.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC079880.1, AK122573.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-26                BB852730.1         1-26
            27-4111             AK122573.1         1-4085
            4112-4152           BC079880.1         4026-4066
FEATURES             Location/Qualifiers
     source          1..4152
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="8"
                     /map="8 53.04 cM"
     gene            1..4152
                     /gene="Ripor1"
                     /gene_synonym="2310066E14Rik; Fam65a"
                     /note="RHO family interacting cell polarization regulator
                     1"
                     /db_xref="GeneID:75687"
                     /db_xref="MGI:MGI:1922937"
     exon            1..122
                     /gene="Ripor1"
                     /gene_synonym="2310066E14Rik; Fam65a"
                     /inference="alignment:Splign:2.1.0"
     exon            123..249
                     /gene="Ripor1"
                     /gene_synonym="2310066E14Rik; Fam65a"
                     /inference="alignment:Splign:2.1.0"
     CDS             146..3817
                     /gene="Ripor1"
                     /gene_synonym="2310066E14Rik; Fam65a"
                     /note="protein FAM65A; family with sequence similarity 65,
                     member A"
                     /codon_start=1
                     /product="rho family-interacting cell polarization
                     regulator 1"
                     /protein_id="NP_001074710.2"
                     /db_xref="CCDS:CCDS52660.1"
                     /db_xref="GeneID:75687"
                     /db_xref="MGI:MGI:1922937"
                     /translation="MMSLSVRPQRRLLSARVSRSQSFAGVLGSHERGPRSFTVFSPPG
                     PPRKPLVLSRVSRMFSVAHPAPKVPQPERLDLVYTALKRGLTAYLEVHQQEQEKLQRQ
                     IKESKRNSRLGFLYDLDKQVKSIERFLRRLEFHASKIDELYEAYCVQRRLRDGAYNMV
                     RAYSTGSPGSREARDSLAEATRGHREYTESMCLLENELEAQLGEFHLRMKGLAGFARL
                     CVGDQYEICMKYGRQRWKLRGRIESSGKQVWDSEETVFLPLLTEFLSIKVTELKGLAN
                     HVVVGSVSCETKDLFAALPQVVAVDINDLGTIKLSLEVIWSPFDKDDQPSAASTVNKA
                     STVTKRFSTYSQSPPDTPSLREQAFYNMLRRQEELENGTAWSLSSESSDDSSSPQLSG
                     TARHSTPKPLVQQPEPLPVQVAFRRPESLTSGSMDEEPAMTPSLVNGHAPYSRTLSHI
                     SEASVDAALTEAVEAVDSQSPIPGPSPLVYPDSTHVERVSSVLPVLNNGHSATSPALS
                     TTGPAPTFIDPAPTTQLDLVHKTTDSAPSELPSITHTTTSSAYSAVSLVNSVPSLTST
                     TIGSAHTTTPSPLTSTGSVPNATDSTQATPSPTHSTPSPTHTTIRLTHTTVSPTHSSP
                     SPIHTTPSPTHTTVSPTCTTPSSGHSTTSPTQEAKMSTHTTGAVGPVQTTTSPISTTE
                     SPSPSTDVAIISSSSAESTGPGTEPLPCSHPASPPYTKADPTASCTSYQSLASSGSKP
                     LTSPAPDSPEQIPKSPSSSPSSSAPEPQHSEHNLAAVAQAPVPEATGGAGDRRLEEAL
                     GTLMSALDDYRGQFPELQGLEQEVTRLESLLMQRQGLTRSRASSLSITVEHALESFSF
                     LNDDEDEDNDGPGDRHTSSPEVVAEDRLDSSNGQSLSTGCSALDATLVQHLYHCSRLL
                     LKLGTFGPLRCQEAWALERLLREARVFQEVCERSKLWGNSATSAQEVVQFSASRPGFL
                     TFWDQCTEGLSPFICSVERVLLTFCSQYGARLSLRQPGLAEAVCVKFLEDALGQKLPR
                     RPQPGPGEQFTIFQFWSYVEALDSPSMDAYVTETAEEVLLVQNLNSDDQAVVLKALRL
                     APEGRLRKDGLRALSSLLVHGNNKVMAAVSTQLRSLSLGPVFRERALLCFLDQLEDGD
                     VQTRVAGCLALGCIKAPEGIEPLVYLCQTDTEAVREAARQSLQQCGEEGQSAHRQLEE
                     SLDALPCIFGPSSMASTAF"
     exon            250..402
                     /gene="Ripor1"
                     /gene_synonym="2310066E14Rik; Fam65a"
                     /inference="alignment:Splign:2.1.0"
     exon            403..481
                     /gene="Ripor1"
                     /gene_synonym="2310066E14Rik; Fam65a"
                     /inference="alignment:Splign:2.1.0"
     exon            482..505
                     /gene="Ripor1"
                     /gene_synonym="2310066E14Rik; Fam65a"
                     /inference="alignment:Splign:2.1.0"
     exon            506..559
                     /gene="Ripor1"
                     /gene_synonym="2310066E14Rik; Fam65a"
                     /inference="alignment:Splign:2.1.0"
     exon            560..712
                     /gene="Ripor1"
                     /gene_synonym="2310066E14Rik; Fam65a"
                     /inference="alignment:Splign:2.1.0"
     exon            713..776
                     /gene="Ripor1"
                     /gene_synonym="2310066E14Rik; Fam65a"
                     /inference="alignment:Splign:2.1.0"
     exon            777..820
                     /gene="Ripor1"
                     /gene_synonym="2310066E14Rik; Fam65a"
                     /inference="alignment:Splign:2.1.0"
     exon            821..946
                     /gene="Ripor1"
                     /gene_synonym="2310066E14Rik; Fam65a"
                     /inference="alignment:Splign:2.1.0"
     exon            947..1095
                     /gene="Ripor1"
                     /gene_synonym="2310066E14Rik; Fam65a"
                     /inference="alignment:Splign:2.1.0"
     exon            1096..1225
                     /gene="Ripor1"
                     /gene_synonym="2310066E14Rik; Fam65a"
                     /inference="alignment:Splign:2.1.0"
     exon            1226..2635
                     /gene="Ripor1"
                     /gene_synonym="2310066E14Rik; Fam65a"
                     /inference="alignment:Splign:2.1.0"
     exon            2636..2757
                     /gene="Ripor1"
                     /gene_synonym="2310066E14Rik; Fam65a"
                     /inference="alignment:Splign:2.1.0"
     exon            2758..2890
                     /gene="Ripor1"
                     /gene_synonym="2310066E14Rik; Fam65a"
                     /inference="alignment:Splign:2.1.0"
     exon            2891..3026
                     /gene="Ripor1"
                     /gene_synonym="2310066E14Rik; Fam65a"
                     /inference="alignment:Splign:2.1.0"
     exon            3027..3188
                     /gene="Ripor1"
                     /gene_synonym="2310066E14Rik; Fam65a"
                     /inference="alignment:Splign:2.1.0"
     exon            3189..3347
                     /gene="Ripor1"
                     /gene_synonym="2310066E14Rik; Fam65a"
                     /inference="alignment:Splign:2.1.0"
     exon            3348..3544
                     /gene="Ripor1"
                     /gene_synonym="2310066E14Rik; Fam65a"
                     /inference="alignment:Splign:2.1.0"
     exon            3545..3628
                     /gene="Ripor1"
                     /gene_synonym="2310066E14Rik; Fam65a"
                     /inference="alignment:Splign:2.1.0"
     exon            3629..3719
                     /gene="Ripor1"
                     /gene_synonym="2310066E14Rik; Fam65a"
                     /inference="alignment:Splign:2.1.0"
     exon            3720..4134
                     /gene="Ripor1"
                     /gene_synonym="2310066E14Rik; Fam65a"
                     /inference="alignment:Splign:2.1.0"
     regulatory      4114..4119
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Ripor1"
                     /gene_synonym="2310066E14Rik; Fam65a"
                     /note="hexamer: AATAAA"
     polyA_site      4134
                     /gene="Ripor1"
                     /gene_synonym="2310066E14Rik; Fam65a"
                     /note="major polyA site"
ORIGIN      
        1 ggcggcggag aggagggagg ggcaggcgcc ggccgcggcg acagcggcag ctgcagcgcg
       61 agcaggccgg gcaacgccga gagtaccgac agcgcgaggt ccttgcagcc cagcgcagcc
      121 atggagcccc gcgcgaactc attccatgat gtccctgtcg gtgcggccgc agcgccgcct
      181 gctcagcgcc cgggtcagta ggagccagtc cttcgcaggc gtcctcggca gccacgagcg
      241 cgggcccagg agcttcactg tcttcagccc accagggccc ccacggaagc ccctagtgct
      301 ctcccgagtg tcaaggatgt tttctgtggc ccatccagct cccaaggtgc cgcagccaga
      361 gaggctggac ctggtgtaca ctgctcttaa gcggggactg acggcctact tggaagtgca
      421 tcagcaggag caggagaagc tccagcgcca gataaaggag tccaaaagga attcccgcct
      481 aggcttcctg tatgacttgg acaagcaagt caagtccatt gaacgctttc ttcgacgact
      541 ggaattccat gccagtaaga ttgacgagtt gtatgaagca tactgtgtcc agcggcgtct
      601 cagggatggt gcctacaaca tggtccgcgc ctatagcact gggtccccag ggagtcgaga
      661 ggcccgagac agcctggccg aggccactcg aggccatcga gagtatacag agagcatgtg
      721 tcttctggag aatgagctgg aggcacagtt gggcgagttt catctccgga tgaaagggct
      781 ggctggcttc gccaggctgt gtgtgggcga tcaatatgag atctgcatga aatatggccg
      841 tcagcgctgg aagttgcgag gccggataga gagtagtggc aagcaggtgt gggacagtga
      901 agagaccgtc tttcttcctc tactcacaga attcctgtct atcaaggtga cagaattaaa
      961 gggactggct aaccacgtag tcgtgggcag tgtctcctgt gagaccaagg acctgtttgc
     1021 cgccctgccc caggttgtgg ctgtggatat caatgatctt ggcaccatca agctaagcct
     1081 agaagtcata tggagtccct ttgacaagga tgaccagcct tcagctgctt ctacagtcaa
     1141 caaagcttcc acagtcacca agcgattttc cacatatagc cagagcccgc cagacacacc
     1201 ctcactccga gaacaggcct tttataacat gttacggcga caggaggagc tcgagaatgg
     1261 gacggcctgg tccctgtcct ctgaatcgtc agatgattca tcaagcccgc agctctctgg
     1321 cacagctcga cactcaactc ccaagcctct ggtgcaacag cctgagcccc tgcctgtcca
     1381 agttgccttc cgaaggccag agagcctcac gtctggttcc atggatgaag agccagccat
     1441 gaccccatcc ctggtcaatg ggcatgcccc ttacagccgg actctcagcc acatcagcga
     1501 ggccagcgtg gatgctgcct tgactgaggc cgtggaagct gtggactcac aaagcccaat
     1561 cccagggcct agcccgcttg tctatccaga ttccacccac gtggagcgtg tcagtagtgt
     1621 tctgcctgtc ctcaacaatg gccattctgc cacaagtccc gccctcagta caactggccc
     1681 cgcccccaca tttatagacc ctgccccaac gacacagcta gacttggttc acaaaaccac
     1741 agactccgcc ccttctgagt tgcccagcat cacacatact acgacaagct ctgcatatag
     1801 tgctgtaagc cttgtcaaca gtgttccaag cctaacttcc accactatag gttctgccca
     1861 cacaaccacg ccctctcccc tcacctccac aggctctgtt cccaatgcaa cagactcaac
     1921 ccaggctacc ccaagcccta ctcacagtac cccaagccct acccatacta ctatacgcct
     1981 cacccacacc actgtaagcc ctacacatag ctccccgagc cccatacaca ctaccccgag
     2041 ccccacccat accactgtaa gtcccacctg cactactcca agctccggcc acagtaccac
     2101 tagtcccact caagaagcca agatgtcaac tcataccacc ggtgctgtgg gcccggtcca
     2161 gaccactaca agtcccattt ccacaactga aagcccctcc ccttctacag acgtggctat
     2221 aatctccagc tcctctgcag aatccaccgg cccaggcact gaacctctgc cctgtagtca
     2281 cccagcctcc cctccctaca ctaaagcaga ccccacagct tcctgcacct cttaccagag
     2341 tcttgcttcc tctggttcaa aacccctcac aagccctgcc ccggattccc cagaacaaat
     2401 ccctaagagc ccaagttcct ctccctcatc tagtgcccct gaaccccaac attcagaaca
     2461 taacctggcc gcagttgctc aagccccagt ccctgaggca acgggaggag ctggggacag
     2521 aaggcttgaa gaagctcttg ggaccctaat gtctgccctt gatgactatc gtggtcagtt
     2581 ccctgagctg cagggcctgg agcaggaggt gactcggctg gagagtctgc tcatgcagag
     2641 acaaggcctg actcgaagcc gggcttccag tcttagcatc actgtggagc atgccctgga
     2701 gagcttcagc ttcctcaatg atgatgaaga tgaagacaac gatggtcccg gggacaggca
     2761 cacaagcagc ccagaggttg tggcagagga cagactagac tcatcaaatg gccagtctct
     2821 aagcacaggg tgttcagccc tggatgctac cttggtccag cacctgtacc actgcagccg
     2881 cctcctgctg aaactgggca catttggacc cctgcgctgc caggaggcct gggccctgga
     2941 acggctgctg cgggaagcgc gtgtattcca ggaagtgtgt gaacgcagca agctatgggg
     3001 gaactctgcc acatctgccc aggaagtggt acagttctcc gcctctcggc ccggcttcct
     3061 gaccttttgg gaccagtgta cagagggact cagccccttc atctgctctg tggagcgggt
     3121 gctcctcacc ttctgcagcc agtacggtgc ccgtctttcc ctgcgccagc caggcttagc
     3181 cgaggctgtg tgtgtgaagt tcctggaaga tgccctggga cagaagctgc ccaggaggcc
     3241 ccaaccaggc ccgggggagc agttcaccat cttccaattc tggagttatg tagaagcctt
     3301 ggacagcccc tccatggatg cctatgtgac agagactgca gaggaggtgt tactagtaca
     3361 gaacctgaac tctgatgacc aggccgttgt gctgaaagcc ctaaggttag caccggaggg
     3421 gcgcctgcga aaggatgggc ttcgggctct tagctccctg ctggtccacg gcaacaacaa
     3481 agtcatggct gctgtcagca ctcagcttcg gagcctgtca cttggtcctg tcttccggga
     3541 aagggctctc ttgtgcttcc tggaccagct ggaagatggg gacgtgcaga ctcgagtggc
     3601 cggatgcctg gctttgggct gtatcaaggc tcctgagggc attgagcccc tggtgtactt
     3661 gtgccaaaca gacacagaag ctgtgaggga agccgcccgg cagagcctgc agcagtgcgg
     3721 ggaggaagga cagtctgctc atcgacagct agaggagtcc ctggatgctc tgccctgcat
     3781 ctttgggccc agcagcatgg ccagcacagc attctgaact cttaattgcc ggctcccagt
     3841 gtcccttccc ttgttttcag ggctcatcag gcactggcag ggagggtgaa ggctggttcc
     3901 agtcacctct ccccacaaat tcctatcaat gaaaatctaa tatattcttt tgttaccact
     3961 ggggttggca gaatgcctga aatgaagtgc ctcccagccg cggttctgca cagtctttgc
     4021 cacacacagt gtcggaggcc tggccatttg gtcagcttgc cttgcctcat cacatccctt
     4081 gggtttgtat tttatttaca gagttttaca gaaaataaaa gaaaaaaaag caaaaaaaaa
     4141 aaaaaaaaaa aa
//
