LOCUS       NM_182929               6538 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus regulating synaptic membrane exocytosis 3 (Rims3),
            mRNA.
ACCESSION   NM_182929 XM_006503101
VERSION     NM_182929.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 6538)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 6538)
  AUTHORS   Picher,M.M., Oprisoreanu,A.M., Jung,S., Michel,K., Schoch,S. and
            Moser,T.
  TITLE     Rab Interacting Molecules 2 and 3 Directly Interact with the
            Pore-Forming CaV1.3 Ca2+ Channel Subunit and Promote Its Membrane
            Expression
  JOURNAL   Front Cell Neurosci 11, 160 (2017)
   PUBMED   28642685
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 6538)
  AUTHORS   Dickinson,M.E., Flenniken,A.M., Ji,X., Teboul,L., Wong,M.D.,
            White,J.K., Meehan,T.F., Weninger,W.J., Westerberg,H., Adissu,H.,
            Baker,C.N., Bower,L., Brown,J.M., Caddle,L.B., Chiani,F., Clary,D.,
            Cleak,J., Daly,M.J., Denegre,J.M., Doe,B., Dolan,M.E., Edie,S.M.,
            Fuchs,H., Gailus-Durner,V., Galli,A., Gambadoro,A., Gallegos,J.,
            Guo,S., Horner,N.R., Hsu,C.W., Johnson,S.J., Kalaga,S., Keith,L.C.,
            Lanoue,L., Lawson,T.N., Lek,M., Mark,M., Marschall,S., Mason,J.,
            McElwee,M.L., Newbigging,S., Nutter,L.M., Peterson,K.A.,
            Ramirez-Solis,R., Rowland,D.J., Ryder,E., Samocha,K.E.,
            Seavitt,J.R., Selloum,M., Szoke-Kovacs,Z., Tamura,M., Trainor,A.G.,
            Tudose,I., Wakana,S., Warren,J., Wendling,O., West,D.B., Wong,L.,
            Yoshiki,A., MacArthur,D.G., Tocchini-Valentini,G.P., Gao,X.,
            Flicek,P., Bradley,A., Skarnes,W.C., Justice,M.J., Parkinson,H.E.,
            Moore,M., Wells,S., Braun,R.E., Svenson,K.L., de Angelis,M.H.,
            Herault,Y., Mohun,T., Mallon,A.M., Henkelman,R.M., Brown,S.D.,
            Adams,D.J., Lloyd,K.C., McKerlie,C., Beaudet,A.L., Bucan,M. and
            Murray,S.A.
  CONSRTM   International Mouse Phenotyping Consortium; Jackson Laboratory;
            Infrastructure Nationale PHENOMIN, Institut Clinique de la Souris
            (ICS); Charles River Laboratories; MRC Harwell; Toronto Centre for
            Phenogenomics; Wellcome Trust Sanger Institute; RIKEN BioResource
            Center
  TITLE     High-throughput discovery of novel developmental phenotypes
  JOURNAL   Nature 537 (7621), 508-514 (2016)
   PUBMED   27626380
  REMARK    Erratum:[Nature. 2017 Nov 16;551(7680):398. PMID: 29144450]
REFERENCE   4  (bases 1 to 6538)
  AUTHORS   Liu,X., Jiao,Y., Cao,Y., Deng,N., Ma,Y., Hasty,K.A., Kang,A.,
            Chen,H., Stuart,J.M. and Gu,W.
  TITLE     Decreased expression levels of Ifi genes is associated to the
            increased resistance to spontaneous arthritis disease in mice
            deficiency of IL-1RA
  JOURNAL   BMC Immunol 17 (1), 25 (2016)
   PUBMED   27480124
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 6538)
  AUTHORS   Takada,Y., Hirano,M., Kiyonaka,S., Ueda,Y., Yamaguchi,K.,
            Nakahara,K., Mori,M.X. and Mori,Y.
  TITLE     Rab3 interacting molecule 3 mutations associated with autism alter
            regulation of voltage-dependent Ca(2) channels
  JOURNAL   Cell Calcium 58 (3), 296-306 (2015)
   PUBMED   26142343
  REMARK    GeneRIF: mouse RIM3 proteins carrying amino acid substitutions that
            correspond to mutations associated with autism (E176A and M259V)
            modify RIM3 interaction with VDCC beta-subunits
REFERENCE   6  (bases 1 to 6538)
  AUTHORS   Munton,R.P., Tweedie-Cullen,R., Livingstone-Zatchej,M.,
            Weinandy,F., Waidelich,M., Longo,D., Gehrig,P., Potthast,F.,
            Rutishauser,D., Gerrits,B., Panse,C., Schlapbach,R. and Mansuy,I.M.
  TITLE     Qualitative and quantitative analyses of protein phosphorylation in
            naive and stimulated mouse synaptosomal preparations
  JOURNAL   Mol Cell Proteomics 6 (2), 283-293 (2007)
   PUBMED   17114649
REFERENCE   7  (bases 1 to 6538)
  AUTHORS   Cachaco,A.S., Chuva de Sousa Lopes,S.M., Kuikman,I., Bajanca,F.,
            Abe,K., Baudoin,C., Sonnenberg,A., Mummery,C.L. and
            Thorsteinsdottir,S.
  TITLE     Knock-in of integrin beta 1D affects primary but not secondary
            myogenesis in mice
  JOURNAL   Development 130 (8), 1659-1671 (2003)
   PUBMED   12620989
REFERENCE   8  (bases 1 to 6538)
  AUTHORS   Okazaki,N., Kikuno,R., Ohara,R., Inamoto,S., Aizawa,H., Yuasa,S.,
            Nakajima,D., Nagase,T., Ohara,O. and Koga,H.
  TITLE     Prediction of the coding sequences of mouse homologues of KIAA
            gene: II. The complete nucleotide sequences of 400 mouse
            KIAA-homologous cDNAs identified by screening of terminal sequences
            of cDNA clones randomly sampled from size-fractionated libraries
  JOURNAL   DNA Res 10 (1), 35-48 (2003)
   PUBMED   12693553
REFERENCE   9  (bases 1 to 6538)
  AUTHORS   Wang,Y. and Sudhof,T.C.
  TITLE     Genomic definition of RIM proteins: evolutionary amplification of a
            family of synaptic regulatory proteins
  JOURNAL   Genomics 81 (2), 126-137 (2003)
   PUBMED   12620390
REFERENCE   10 (bases 1 to 6538)
  AUTHORS   Cheung,K.J. Jr., Bush,J.A., Jia,W. and Li,G.
  TITLE     Expression of the novel tumour suppressor p33(ING1)is independent
            of p53
  JOURNAL   Br J Cancer 83 (11), 1468-1472 (2000)
   PUBMED   11076655
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL606904.12, BB647733.1, CJ115394.1, CF536669.1, BB254179.2,
            CF746476.1, BQ442807.1, CB526755.1, CK781515.1, CA315185.1,
            CF537752.1 and AW491516.1.
            
            [WARNING] On May 3, 2024 this sequence was replaced by NM_182929.4.
            
            On or before Sep 18, 2017 this sequence version replaced
            XM_006503101.1, NM_182929.2.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR1660811.31542.1,
                                           SRR7974084.16639.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-20                AL606904.12        93424-93443
            21-136              BB647733.1         1-116
            137-655             CJ115394.1         3-521
            656-746             AL606904.12        116620-116710
            747-888             AL606904.12        121700-121841
            889-921             AL606904.12        125559-125591
            922-1507            CF536669.1         1-586
            1508-1748           BB254179.2         143-383
            1749-2346           CF746476.1         58-655
            2347-2721           BQ442807.1         295-669
            2722-2828           CB526755.1         189-295
            2829-3516           CK781515.1         8-695
            3517-4008           CA315185.1         217-708
            4009-4489           CF537752.1         197-677
            4490-5983           AL606904.12        133169-134662
            5984-6538           AW491516.1         1-555               c
FEATURES             Location/Qualifiers
     source          1..6538
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="4"
                     /map="4 56.58 cM"
     gene            1..6538
                     /gene="Rims3"
                     /gene_synonym="A730060M23Rik; mKIAA0237; Nim3; Rim3"
                     /note="regulating synaptic membrane exocytosis 3"
                     /db_xref="GeneID:242662"
                     /db_xref="MGI:MGI:2443331"
     exon            1..324
                     /gene="Rims3"
                     /gene_synonym="A730060M23Rik; mKIAA0237; Nim3; Rim3"
                     /inference="alignment:Splign:2.1.0"
     exon            325..498
                     /gene="Rims3"
                     /gene_synonym="A730060M23Rik; mKIAA0237; Nim3; Rim3"
                     /inference="alignment:Splign:2.1.0"
     exon            499..746
                     /gene="Rims3"
                     /gene_synonym="A730060M23Rik; mKIAA0237; Nim3; Rim3"
                     /inference="alignment:Splign:2.1.0"
     CDS             530..1453
                     /gene="Rims3"
                     /gene_synonym="A730060M23Rik; mKIAA0237; Nim3; Rim3"
                     /note="RIM3 gamma; rab-3-interacting molecule 3"
                     /codon_start=1
                     /product="regulating synaptic membrane exocytosis protein
                     3"
                     /protein_id="NP_891559.1"
                     /db_xref="CCDS:CCDS18595.1"
                     /db_xref="GeneID:242662"
                     /db_xref="MGI:MGI:2443331"
                     /translation="MFNGEPGPASAGASRNVVRSSSISGEICGSQQAGGGAGTTTAKK
                     RRSSLGAKMVAIVGLTQWSKSTLQLPQPEGATKKLRSNIRRSTETGIAVEMRSRVTRQ
                     GSRESTDGSTNSNSSEGTFIFPTRLGAESQFSDFLDGLGPAQIVGRQTLATPPMGDVH
                     IAIMDRSGQLEVEVIEARGLTPKPGSKSLPATYIKAYLLENGACVAKKKTKVAKKTCD
                     PLYQQALLFDEGPQGKVLQVIVWGDYGRMDHKCFMGMAQIMLDELDLSAAVTGWYKLF
                     PTSSVADSTLGSLTRRLSQSSLESATSPSCS"
     exon            747..888
                     /gene="Rims3"
                     /gene_synonym="A730060M23Rik; mKIAA0237; Nim3; Rim3"
                     /inference="alignment:Splign:2.1.0"
     exon            889..998
                     /gene="Rims3"
                     /gene_synonym="A730060M23Rik; mKIAA0237; Nim3; Rim3"
                     /inference="alignment:Splign:2.1.0"
     exon            999..1100
                     /gene="Rims3"
                     /gene_synonym="A730060M23Rik; mKIAA0237; Nim3; Rim3"
                     /inference="alignment:Splign:2.1.0"
     exon            1101..1240
                     /gene="Rims3"
                     /gene_synonym="A730060M23Rik; mKIAA0237; Nim3; Rim3"
                     /inference="alignment:Splign:2.1.0"
     exon            1241..6521
                     /gene="Rims3"
                     /gene_synonym="A730060M23Rik; mKIAA0237; Nim3; Rim3"
                     /inference="alignment:Splign:2.1.0"
     polyA_site      6505
                     /gene="Rims3"
                     /gene_synonym="A730060M23Rik; mKIAA0237; Nim3; Rim3"
                     /note="major polyA site"
ORIGIN      
        1 agggcccgct tcctcccgcc agccgtggct tgggctttgc acccggcggc gactgagaac
       61 tgtgtggcga ctgcggagcc agcagcgcag gcgggcggag cggagctgtc cggcccggtg
      121 gcgggcgatg cccccgtgag tctctgtcgc tgcccctccc cgccccgcgt ccctacccct
      181 tcggagtccg cgcccgctcg gggccgggcc gcgcctaccg ccgggtccgc ggggcggggt
      241 cccggggcag cacctgcctc gccttgcggc gccactccgc cagcggaatc ccgctccagg
      301 cgtggacccc ggccccacct cgggaccctg tcatcgcatt ccttccccct ggaagcctgc
      361 cctgattgcc tttacttcct tttctggaaa ttgctatctc agcagaagtg aagctttgtg
      421 cgattcccta gggggtgtgc tgttgagaga gcacagcccc ttgtgatgcg gagcaccaca
      481 ctcagactca gcagcttgaa ttgcctgaag ccctgccatc ctggggacca tgtttaacgg
      541 ggagcctggt ccagcctcgg caggggcctc caggaatgta gtaaggagtt ccagcatcag
      601 cggtgagatc tgtggatccc agcaagctgg aggtggggcc gggaccacca cagccaagaa
      661 acggcgcagc agcctgggtg ccaagatggt agctatcgtc ggcttgaccc agtggagcaa
      721 aagcaccttg cagctccccc agcctgaagg ggccaccaag aagcttcgaa gcaacatccg
      781 acggagcaca gagactggca ttgcagtgga gatgcggagc cgtgtaaccc gccagggcag
      841 ccgggagtct accgatggga gcaccaacag taacagctcc gagggcacgt ttatttttcc
      901 cacacggctt ggagctgaaa gccagttcag tgactttctg gatggcctgg gaccagccca
      961 gattgtgggg cgacagacgc tggccacacc ccccatggga gatgtgcaca ttgccatcat
     1021 ggaccggagt ggccagctgg aggtggaagt gattgaagct cggggcctga cccccaaacc
     1081 aggctccaaa tccctcccag ccacctatat caaggcttac ctgctggaga acggggcatg
     1141 tgtagccaag aaaaagacaa aggtggccaa gaaaacatgt gatcccttgt accagcaagc
     1201 tctgctcttt gatgaggggc cccaaggcaa ggtcctgcag gtgatcgtct ggggagacta
     1261 cggccgtatg gaccacaagt gcttcatggg tatggcccag atcatgctgg acgagctgga
     1321 cctgagtgct gcagtcaccg gctggtacaa actcttcccc acatcctctg tggccgactc
     1381 cacactcgga tccctcacca ggcgcctgtc tcagtcctct ttggagagtg ccaccagccc
     1441 ctcgtgctct taaggacctc gatgaggaca agaggccagg ggctattggg ggatgggagc
     1501 ctgctggcct caccaccccc tgtacatagt ctccatgtcc ttctgaaccc cttatcctgc
     1561 tgcatgcctg ttagccactg ggctcgtccc agctggcagt ggagactata gtgtgtgtct
     1621 gtgtgtctct ctgtgtgtgt gtgtccacat atttgtccat ttgtctgtgt acaatcagtc
     1681 ctggtgatca catggactat atagtccaca tctctgtatc ttgctggaaa gaacccaaag
     1741 gagcatcgta tggacacttc ttgcccatgg aatctccagg ggtggaaata ggggatgtgg
     1801 ccactggtgg gccttgctta gtccctgcct tgttgtctta tggtctccac ttgcttttct
     1861 gtcttgtctt tttctttgcc tctcccagca ttgctgcttt tttgaggaat gtagcatcca
     1921 ttgcagctga ccacacctgg ttccatctag aaatctacat ctctcctccc taccacagcc
     1981 acactggtgg tcatcccatt gaatgcactc cacagcatgt agcatgctca ctcagtgccc
     2041 tagccagggc cccaggacag agggtgtctg gggaggagga tgcaggccag gcacactaga
     2101 ggatgtactg ggacctctct tcccctgggg tgttccaaca tgccagagga gctcccagtg
     2161 gacccaggag gctgcctgtt gaagtagctg gccttttcag gcatcaaggt ggccctgtcc
     2221 ccctttgggg ttattcctga gggagcatgg cttggtaaga ggtgccatgg gtagggctac
     2281 ttgctggagg aaggagggct aaggttaatt tgttttgagc cactgtctgg aaacctgtct
     2341 gacctggggt tagctgcacg aagctattct ttcagggttc tactttcttt gctcatctgt
     2401 agacaccaga ccccatctgg agttctgaca caccagagct ccagcctcct agctctgtgg
     2461 gcagcctggc tctgcattca agggtgcctc agtcaccagc tctgtaccag caatactcac
     2521 ccctccacct ccctgacttt cttgagtggg cccctgctct aggcatccca gctgcctcta
     2581 ccttactacc cccttccctt gtctggctag ggctcctccc aaccactgag aacactgttg
     2641 gagggactag tgcctgggcc agatcccaag atggctgatg tgaatactga aggctggctc
     2701 tggactgctg catctgttct cccctcctta gctatagggt ggggttggag gctgcctggg
     2761 agatggcaaa gtagccctgg tttatgtcga gtaggaggaa ggacacaggt gatgggtggg
     2821 agatggggaa gactctcttt ctgcctctct cctagcccat gcctctagca taagtgccta
     2881 ggcagggaga gctatgggga taactgtgaa gcagcgttgg cctgtgtgtg gatctcattt
     2941 gtaccaaagc tggggtacac aaagctgtct cagcccaaag ggcctccctg tagtcagagt
     3001 cctgcactca gtgtcaaaga agggctgtga agaagccccc atgcaaactg gggtgaggag
     3061 gaggaagaga aggaacagac cggggctgtg tccctgcagg caggagaggg aggcgggggc
     3121 cagttctctt gccagccttt ctggctaggg agtatatatg tatctcccat atcactagat
     3181 atggggcaaa gtgctcttgg tctccaagcc ttaatggttt gggggcaagg agaaaactag
     3241 cttgtggaag gctgttttcg tcttgcttga ggtgtgcgca cctttaaagc agttaccggc
     3301 tggatggtgt gaaagccatc tggagtggag gagtgtcagt gacccactga caacagagag
     3361 ctttgcagat gtggcgtcga gtcactccca gaagtgggag ctgccagcag agagtgtccc
     3421 ttgcctctta ggagggtcag cacaggggat actctagcca gaggagggac ttgatgtgct
     3481 gggaactcgt gctgacctgc ctacagtcag aggctgtaaa ctacctaaga gatgggcact
     3541 tggcggcccc acctccatgg aagatagccc ccctccccaa ttgattttgg ggaattcacg
     3601 cttcttaaca ctgagtaacc ccttctagat gctcgctccc acgtgtgggt tgtgtaaggc
     3661 tagtgtgtac atgtgatgag gaggctgggt ttaacgctct gtttctcagc acactggatt
     3721 gggggctaca ctgggtggga tgccattcca gaagcaggtg tgcccaagtg tgactcctgc
     3781 ctgggctggg agccatctgc cctttgagga aaggacaatg gatcaagaat tagccgggtg
     3841 cttgtgagtt cacctatcaa caggccacct cacataacct cttgctccag gggtcagtgg
     3901 ttgcaggagt gggatttggt catcccatct cctctaggca ggccagactc gtcggtgatg
     3961 ggctgggaca ggagcagccc tgcagcgatg ctgggctgtg ggcaggggca gtgataaatg
     4021 actcagagca tatgtctctg tatttctgcc ctgctcagcc tgtcccactt tttaacagat
     4081 tcctttccta caaggaaagc agagatggga ctctgtgata tgaagcggtc tctaggaaat
     4141 gggccaagtc ttggtttgac agggacattt gatcctttgg ggaggaaccg gctccagagg
     4201 cgctctcatc ttgcctctca gctcaccaga ctctgaacat cacctcttca gcaggttccg
     4261 ggcagtgcca gcacactatg gggtggaggc agagctgcag gaagctccag agaggaaggg
     4321 gtggtagtgc ctggatggtt ctgctcttgg ggactcggtg cctggagcac tggggtcaag
     4381 ctaactctcc caggggctca gcccctgacc agggaagcat gccagctctt ccttaactgc
     4441 cagcctggga gagaccagca gcctccgttt ttgtttttgt ttttgtttta aagacaactg
     4501 agccctccca gggcatttct ttgaaaatga aatgtagcac aatcctcaac tgtgttccca
     4561 ggagccctga catacccagg gctcctgata cctcacattc tccatcgccc ttggcctagg
     4621 aggcagtagt gccctagcaa ggctgctctt ctgtatttct ccgattgcgt ccagcactgt
     4681 gcagactctt taagaagttg cttcctttgc ccgaggttgc tctccaccgg gtggggagat
     4741 gcggtacttc atgtggtggc ctgaagcttg tccagcagca tttctgtagc ggccacaggg
     4801 aagtggacaa gaggaggcct gctttcctgc caccaccttt tctctcccac tcctcagttg
     4861 ttgtctctaa tgttctgaca catacagacg ttctttggaa cacagcccct ctccttcgtc
     4921 gtcgtcttct gatggatgat cagagaggag atggaaatgc agactccttc cctgccttct
     4981 ccctccagtc tgcttctagc ccaggtcaga agagttcaga agaagctagg gagatcaacc
     5041 accatcagag agcaggggcg gcccatccag tcagcctggc ctggctggga gagggtcatt
     5101 tggagagtgc ctgagcatct cggagcaatg tcagtgatgc caaagagagc gacttggcct
     5161 ccgtgggcag cagctctgtc ggtggagcta gatgaacaca gctcagatgg tggcgtgccc
     5221 aagggagggt ccttgttctc tgacaaaggg cttaatcttt ccatgtagca aagcaactcc
     5281 cttcccccaa ccccgagcat gggcttctgt gggcccggca tggctgtgcc tctaagagaa
     5341 gccgcagagg cgagagacct tctctccttc ctgtctgtct tagcaagtgc tccttgaaaa
     5401 gcctgtgttg ctgctttgga gaaacccagc tctggctgga cagtcgccag taaggacagg
     5461 gccttgggcc tgcaaggaag tccatattga tgccaggaag ggtccctggg cctgagattc
     5521 cagggacaac tgagcatctg ccccattagc caatgaccta gacagggatg gctgttctgt
     5581 accttttttt cttctttttt tctttttgcc agaaactgtg accttgtgtc ctcatctgta
     5641 aaaaccagag cattcgctgg ttgctccatg gccccctcca ggctttgtaa gtctatggct
     5701 tggagttgct gaggtggcta ggggcctgtt tcatccccct tggttctcac tctgggagcc
     5761 tgtcctcatt tggtccatgc ccagatgctg ctcctgaaaa gcccaggtgt agcttcacct
     5821 ctgtgtggtt tgccctcctc ctcccactct ctctggtctt ggtgagaaat aaccaagggt
     5881 cttctacggt ggacagttcc ctaggtgctg taatgtcacc acctaggctg aatcctgagt
     5941 agatctatgt ccctgccagc agtcaggctg ggccacctgt cattctgctt ctagatgaca
     6001 ggccaggaag agtggacact cagagccctt tcaaaggaat tctctctgat gggatgagag
     6061 agagaacgtc cttccaagta tttggctttt taaaaccact tcttcccaaa tttcttctcc
     6121 aaaactttct cttggaaggc aatttggctg cttcctcagg gaaagcagac ctgagacttc
     6181 ttagcaactc ctgtagcaat gagaactcac agaaggcagg aacccctttt ttagaatttc
     6241 caattgcatc ctgcaaagag agagcgcgcg agagaaagtg agagctgtta gggactgaca
     6301 agcacactgt ttagataaaa gcaattagcc ttttctattt gagctctctg cagcatcttc
     6361 ccaaaccgtg gctcctgggt ggcaggtgga cagctgggag ggaataccgg ctgcctcatg
     6421 tgatgtcctt gccaatcccc ctgaggagaa aattcttcac atggcttctg catgtacagt
     6481 atttgggcaa aaaacaaaaa ataaagtcca tttgaaattg gaaaaaaaaa aaaaaaaa
//
