LOCUS       NM_145930               5078 bp    mRNA    linear   ROD 02-MAY-2024
DEFINITION  Mus musculus RAB7A interacting MON1-CCZ1 complex subunit 1
            (Rimoc1), mRNA.
ACCESSION   NM_145930
VERSION     NM_145930.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 5078)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 5078)
  AUTHORS   Koscielny,G., Yaikhom,G., Iyer,V., Meehan,T.F., Morgan,H.,
            Atienza-Herrero,J., Blake,A., Chen,C.K., Easty,R., Di Fenza,A.,
            Fiegel,T., Grifiths,M., Horne,A., Karp,N.A., Kurbatova,N.,
            Mason,J.C., Matthews,P., Oakley,D.J., Qazi,A., Regnart,J.,
            Retha,A., Santos,L.A., Sneddon,D.J., Warren,J., Westerberg,H.,
            Wilson,R.J., Melvin,D.G., Smedley,D., Brown,S.D., Flicek,P.,
            Skarnes,W.C., Mallon,A.M. and Parkinson,H.
  TITLE     The International Mouse Phenotyping Consortium Web Portal, a
            unified point of access for knockout mice and related phenotyping
            data
  JOURNAL   Nucleic Acids Res 42 (Database issue), D802-D809 (2014)
   PUBMED   24194600
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC137902.10.
            
            On Apr 22, 2019 this sequence version replaced NM_145930.2.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK154940.1, AK045350.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN00849374,
                                           SAMN00849375 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-132               AC137902.10        183038-183169       c
            133-239             AC137902.10        179781-179887       c
            240-386             AC137902.10        179141-179287       c
            387-518             AC137902.10        176978-177109       c
            519-633             AC137902.10        176014-176128       c
            634-5078            AC137902.10        169458-173902       c
FEATURES             Location/Qualifiers
     source          1..5078
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="15"
                     /map="15 1.84 cM"
     gene            1..5078
                     /gene="Rimoc1"
                     /note="RAB7A interacting MON1-CCZ1 complex subunit 1"
                     /db_xref="GeneID:106064"
                     /db_xref="MGI:MGI:2146232"
     exon            1..132
                     /gene="Rimoc1"
                     /inference="alignment:Splign:2.1.0"
     CDS             33..917
                     /gene="Rimoc1"
                     /note="UPF0600 protein C5orf51 homolog"
                     /codon_start=1
                     /product="RAB7A-interacting MON1-CCZ1 complex subunit 1"
                     /protein_id="NP_666042.2"
                     /db_xref="CCDS:CCDS27360.1"
                     /db_xref="GeneID:106064"
                     /db_xref="MGI:MGI:2146232"
                     /translation="MAAAVSGVVRRVEELGDLAQAHIQHLSEAAGEDDHFLIRASAAL
                     EKLKLLCGEEKECSNPSNLLELYTQAILDMTYFEENKLVDEDFPEDCSPQKVKELLAF
                     LSEPEILAKESNMHPKLCGLLGAELLECLSWRRGALLYMYCHSLTKRREWLLRKSNLL
                     QKYLVDGINYLLQMLNYRCPVQLNEGVSFQDLDTAKLLSTGVFSDIHVLAMMYSGEMC
                     YWGLKHCTDQQSENHEVDTDVFGASCTTHKETLDFREVGEKILKKYVSVCEGPLKEQE
                     WNTANAKQILSFFQQRCS"
     exon            133..239
                     /gene="Rimoc1"
                     /inference="alignment:Splign:2.1.0"
     exon            240..386
                     /gene="Rimoc1"
                     /inference="alignment:Splign:2.1.0"
     exon            387..518
                     /gene="Rimoc1"
                     /inference="alignment:Splign:2.1.0"
     exon            519..633
                     /gene="Rimoc1"
                     /inference="alignment:Splign:2.1.0"
     exon            634..5078
                     /gene="Rimoc1"
                     /inference="alignment:Splign:2.1.0"
     regulatory      5059..5064
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Rimoc1"
                     /note="hexamer: AATAAA"
     polyA_site      5078
                     /gene="Rimoc1"
                     /note="major polyA site"
ORIGIN      
        1 acgtggacag ggcgggcgcg cccgagctgg ccatggcggc cgcggtgtcc ggtgtggtga
       61 ggcgggtgga agagctcggg gacctggctc aggctcacat acagcacctt agcgaagccg
      121 cgggggaaga cgatcacttt ttaattcgag cctctgcagc tctagaaaaa ttgaaacttt
      181 tatgtggaga agagaaagaa tgttcaaatc catccaatct tttggaacta tatacacagg
      241 ccatcctgga catgacatat tttgaggaga acaagctagt agatgaggat tttccagagg
      301 actgttctcc acagaaagta aaagagctgc tcgcgtttct ttcagaacca gaaatcttag
      361 ctaaagaaag caatatgcat cccaagctgt gcggtttgct tggggctgag ctcctggagt
      421 gcctctcttg gaggcgaggg gccctgctgt acatgtattg tcattcgctg actaagagaa
      481 gggagtggct cctcagaaaa tccaacttgc ttcaaaagta ccttgttgat gggatcaatt
      541 acttgctaca gatgctaaat tatcgatgcc ctgtccagtt aaatgaaggt gtttctttcc
      601 aagacctaga cacagctaaa ttgctgagta caggagtctt tagtgacatc catgtgctgg
      661 ctatgatgta cagtggagag atgtgctact gggggttaaa gcactgcaca gatcagcagt
      721 cagaaaacca tgaagttgat actgatgttt ttggagcaag ctgcaccaca cacaaagaaa
      781 ccttggattt ccgagaagta ggagaaaaaa ttttgaagaa gtatgtgtcg gtgtgtgaag
      841 gacctctgaa ggagcaagag tggaacaccg caaacgcaaa gcaaatctta agtttctttc
      901 agcagcgctg tagctaggtg ttcatctagg tctcaactca aatacataaa gatgctgaag
      961 tggggaagaa ggctttgaca aaggagatgt actacactga tcttgagacg gttacactac
     1021 ataaaggtgc ccagtgcact acgcttctct aatgctgtca cctttccctg agtggtctta
     1081 ggtctgtgaa gaatattctc taatttctag aatggcatat atgccattct aactgaactt
     1141 gaactacata taaacctgcc actggtaagg aggaacccaa tgtagatgga cagttgtttt
     1201 ctaatatttt aggttatatt ttttattgta ctaaaatata tgtaacacag aatctcctta
     1261 ttttgaagta tgcatacttc aaagatggaa atcaggtttt ctccttgttt caaatataaa
     1321 gtatagctat aaatgtaggc aattagaata ttgtgactaa tatttagatt tcatttccag
     1381 taattaaaca acaaaggatt taaaagatga aacttattta ttttgccatg cattactaat
     1441 aatacttaat ttacttatcc attttataaa ttattttatt ttatttaaaa caaaaactgc
     1501 atggttactc caaaaagaag gtaaattcag tatagatgag accaccatta gttcagatgc
     1561 ttgtagggca catctttgca tataatgaac tttacacata ttttgccttt cagtaagact
     1621 gaaatgctga aggccaaaga gcctagtttg ctgtcttgct cacctttctc tgcctacctc
     1681 aagtcttccg atgcactaga cttctgtccc agtgacatct tcacattcct gtcatttctg
     1741 taactgaatc taagcatgag ccacactcag tttctctttc tgaagtctta cattttagta
     1801 actgatgaca gttctcttct tttcagcttt taaaatttct ttgttttcat tggtttttct
     1861 gttttcattc tacagctttc aaccttttca cgggcttctc tagactgctc taactcctga
     1921 acagcgacct ctttcatgtt tttttttgcc ccctacttca tggggcatca tcacatgaat
     1981 actggcctcc cttgtttcct ctcctatttt atctccttgg cagcatcatc cttggcaggc
     2041 tctcagcact gcattaatct tgtcagccag tcattcttag gagactaagt tttatggaag
     2101 gcatgcaatc cttcaaagtg tattgctaca cattgacttc acttaacaat cctaactgca
     2161 aagctactaa ggtgcctccc cttttcccac catggtagag tcaaagttca ttagtcacct
     2221 ctacccttgc tcttccacag gaagtttaga ttatgaggga gtcaactcta tttatgcatt
     2281 tttctgtttt aaaggagaag aatttgccta atttctgttg aagactgatc tttgttattt
     2341 cttctttctc ctgtagtttc tcattttctg cctgtcctca tgaaagtttc attctcttcc
     2401 ttctcttttt ctctttactc taaatactca tggcaagcag tatttctcac tgccatcatg
     2461 gcttatgcca cctataatgt taggctggtt tccatgccag gaactggaac cccactctcc
     2521 ttgctctctg aatttcattt ttaattgact gctaaatgtc ttcactttga caaatactga
     2581 ctgcatggtc attttaagtt caatatgagc aaataacaaa tttttatctc ttatggaaat
     2641 cttttctgcc tcatttccct ccaattttgt atgttttcca aataagcaaa tagaaggcct
     2701 actttccatc cttatttctg cacacactct gatttgtgtt ctagaccaac ggttttcaga
     2761 cattaaaatg cgaggttcct ttttgataaa cagaattctg aataagcagt ggaagccaag
     2821 ggagattcca caatccctgc cacaactctt ggcctgtctt tatacagcca agatttttat
     2881 gtaacctagc attttagcaa gttttattag gaaaatattg tagctttcta aatctttaat
     2941 gtgaatttta gaagcacaga tttctttagt ggatcataat cagttaatca agtgcttcca
     3001 ctccctttcc caaatgcact tatgttttac aaccatagta ccgttgtaga cgtcattatt
     3061 gctggactgg tctttgtggc cagataaatt actttacttg tatgacgtac ctttaggaat
     3121 actgtgtcta aaggcttttt tcagcccttt ccagtagaaa ttagatgttc ctttattttc
     3181 tcgcttcctt tcacatgtca ccacagtaca atgtgttgta attttttttc ttactactga
     3241 acgaactcca tatcttaaaa ttttatcttt gcacacactg ttcattgcat ggtaggtagt
     3301 aatgtcttct gaattaatga ggcatgattt gaaatgccaa actttgcaca agacggttgc
     3361 tgctattgca ttccaaactg ccatgccctc tataccagtg gttgatatag caaaagggag
     3421 catgtcttcc tcggaggagt caagtgttac ctggacacta aacctgagaa aataagactg
     3481 tcttcacaag ctgagaactt ccatttttgc ctttatgacc tttgggggct cactggttga
     3541 tacaattatg agggtatttc tgggtgcttt ttgtacaatt tactccccta ccccaaacaa
     3601 ttggagagca atttatagac cataatagtt gtagtacttt ctactgtggt gttataaaag
     3661 gaaaatacat cttttggtat taatcttgat gagtaaattg ttttatttag aatgaagtaa
     3721 cctcaaaata acaaatactc cacataacaa taagcctata atagaccctt tcaatagcta
     3781 atatgtgcct acaacatgcc atattttgtc ctaggcactg aggatataaa caccctcctg
     3841 ttacaggctt ttagtggagg aagaatgtac agtatgccaa gtgataacac acttagcagg
     3901 gtgtagggga ctattgtgac gtggagatgg tgctattgta tttagagtgg ttagaaagat
     3961 ccatctaagc actgtcttca atttccatcc tgttttttct gatgccttgt gtatgcagta
     4021 catctgaaga ttttcctaag gaagtggctc ttaaaacctc cttttattga atctaatggc
     4081 tttctcattc gtggtgtttc tgatgcctac agcctaaagg tcttgggttc tttattcact
     4141 tgaggtggtt ttctgtccac cgcccagttc ccttttctat cttctatacg gttattacat
     4201 ctttccacag aaaccaaaac tctgtactgt ctttagtatt acttccctat tattttaaac
     4261 acagtatgaa gtagcattgt atggaaacat tacagtaaga ggtacttaat atagacacag
     4321 cgtatgtatt atatcatgct ggtgtttggt agcttttgct ttcctgcgtc tagtgaaaat
     4381 ttatcttcgg tttgaattct ctgctgttga ttaaatgtaa aatgttacag gattttccca
     4441 caatccttaa acgtttatca ctctttactc agtgtgagtt ttctgatgtg gagtagactt
     4501 taagacttga tttaagagcc tgtctctctt gctatgttta taggctgtct ggctgctgtg
     4561 cattatttca tgttaagtca catatcatga catcccctta tcctttgctt acagtggaaa
     4621 aaggtgaaag tcatgactaa gaggccacca taaaagatac attcccagcc tcacaatctt
     4681 gtgctcagtc ttgtgatgtt cattaaagta tgaactgtgt ctgaaggtgt tttccagtta
     4741 tcttcatgac attttaaata cccaccgcta ctaacttggt ctgcttgtag attgcttgtc
     4801 tcctggggcc cctttataac tccatgagga tatttcatct gtcacagagt ccaggattca
     4861 atagtcctct agtattactt acccttcatt catttactat aaaaggaaat agattataaa
     4921 agtattatgt ctacataagc ttaagatagc caggattaaa agtattcatt atgtactatg
     4981 ccggtgtttc ctagttttgt ttttgcaaat tttagtgaca tgttccagct acagtgtttt
     5041 ggaacatata cttaataaaa taaaacgaaa ccccccta
//
