LOCUS       NM_008287               1011 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus reactive intermediate imine deaminase A homolog
            (Rida), mRNA.
ACCESSION   NM_008287
VERSION     NM_008287.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1011)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 1011)
  AUTHORS   Ingham,N.J., Pearson,S.A., Vancollie,V.E., Rook,V., Lewis,M.A.,
            Chen,J., Buniello,A., Martelletti,E., Preite,L., Lam,C.C.,
            Weiss,F.D., Powis,Z., Suwannarat,P., Lelliott,C.J., Dawson,S.J.,
            White,J.K. and Steel,K.P.
  TITLE     Mouse screen reveals multiple new genes underlying mouse and human
            hearing loss
  JOURNAL   PLoS Biol 17 (4), e3000194 (2019)
   PUBMED   30973865
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 1011)
  AUTHORS   Sinha,S., Rappu,P., Lange,S.C., Mantsala,P., Zalkin,H. and
            Smith,J.L.
  TITLE     Crystal structure of Bacillus subtilis YabJ, a purine regulatory
            protein and member of the highly conserved YjgF family
  JOURNAL   Proc Natl Acad Sci U S A 96 (23), 13074-13079 (1999)
   PUBMED   10557275
REFERENCE   4  (bases 1 to 1011)
  AUTHORS   Samuel,S.J., Tzung,S.P. and Cohen,S.A.
  TITLE     Hrp12, a novel heat-responsive, tissue-specific, phosphorylated
            protein isolated from mouse liver
  JOURNAL   Hepatology 25 (5), 1213-1222 (1997)
   PUBMED   9141440
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BU559752.1, BC125592.1 and AW045776.1.
            
            On Dec 12, 2009 this sequence version replaced NM_008287.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AI196495.1, BC092375.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849386, SAMN01164131
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-100               BU559752.1         4-103
            101-571             BC125592.1         1-471
            572-1011            AW045776.1         1-440               c
FEATURES             Location/Qualifiers
     source          1..1011
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="15"
                     /map="15 14.34 cM"
     gene            1..1011
                     /gene="Rida"
                     /gene_synonym="HR12; HRP12; Hrsp12"
                     /note="reactive intermediate imine deaminase A homolog"
                     /db_xref="GeneID:15473"
                     /db_xref="MGI:MGI:1095401"
     exon            1..194
                     /gene="Rida"
                     /gene_synonym="HR12; HRP12; Hrsp12"
                     /inference="alignment:Splign:2.1.0"
     CDS             130..537
                     /gene="Rida"
                     /gene_synonym="HR12; HRP12; Hrsp12"
                     /EC_number="3.5.99.10"
                     /note="ribonuclease UK114; heat-responsive protein 12;
                     translation inhibitor L-PSP ribonuclease"
                     /codon_start=1
                     /product="2-iminobutanoate/2-iminopropanoate deaminase"
                     /protein_id="NP_032313.2"
                     /db_xref="CCDS:CCDS27418.1"
                     /db_xref="GeneID:15473"
                     /db_xref="MGI:MGI:1095401"
                     /translation="MSSIIRKVISTTKAPAAIGPYSQAVQVDRTIYISGQVGLDPSSG
                     QLVPGGVVEEAKQALKNLGEILKAAGCDFNNVVKTTVLLADMNDFGTVNEIYKTYFQG
                     SLPARAAYQVAALPRGSRVEIEAIAVQGPFIKA"
     exon            195..300
                     /gene="Rida"
                     /gene_synonym="HR12; HRP12; Hrsp12"
                     /inference="alignment:Splign:2.1.0"
     exon            301..355
                     /gene="Rida"
                     /gene_synonym="HR12; HRP12; Hrsp12"
                     /inference="alignment:Splign:2.1.0"
     exon            356..424
                     /gene="Rida"
                     /gene_synonym="HR12; HRP12; Hrsp12"
                     /inference="alignment:Splign:2.1.0"
     exon            425..480
                     /gene="Rida"
                     /gene_synonym="HR12; HRP12; Hrsp12"
                     /inference="alignment:Splign:2.1.0"
     exon            481..994
                     /gene="Rida"
                     /gene_synonym="HR12; HRP12; Hrsp12"
                     /inference="alignment:Splign:2.1.0"
     regulatory      970..975
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Rida"
                     /gene_synonym="HR12; HRP12; Hrsp12"
                     /note="hexamer: AATAAA"
     polyA_site      994
                     /gene="Rida"
                     /gene_synonym="HR12; HRP12; Hrsp12"
                     /note="major polyA site"
ORIGIN      
        1 gaattcgcac ggggctgtcc ctgaactaaa actcttttgc ctagggctgt ctggtcagtg
       61 gacaagagtg ggtgtagtta cttaccatcg tttcttcttc tggagggtct tcaagaggga
      121 aggattagca tgtcgtccat aatcagaaag gtgatcagca ccacaaaagc cccggcggcc
      181 attggtccct acagtcaagc tgtgcaagtg gacaggacca tttacatttc tggacaggta
      241 ggcctggatc cttccagtgg acagcttgtg ccaggaggag tagtagaaga agctaaacag
      301 gctcttaaaa acttgggtga gattctgaaa gctgcaggct gtgacttcaa taatgtggtg
      361 aaaacaactg ttttactggc tgacatgaat gactttggca ctgtcaatga gatctataaa
      421 acatatttcc agggtagcct tcctgccagg gctgcttacc aagtcgctgc tttacccaga
      481 ggaagtcgag ttgaaatcga agcaatcgct gtccaggggc ctttcatcaa ggcatgacta
      541 taagtagcca tgctgatgtt gactccggag gttttagaat gtctttcaca ctttaatttt
      601 tacaaatgat gctgggaagt ataaaaatga ccagagtggt tgaagttatt gtggaagtga
      661 tcaaatatgt ggagatttga cattaattgg agattattca gtatagtgac tgatgttcta
      721 atttcactta tgttgctggg tgtgagagaa gaggtgcaca gctactgaga tgggaagcag
      781 aaggaaagat gggctgttgt acatgagaaa tagtaaggag cacatctact taaatcatat
      841 taatttgctc atgtgaaata cttagttctt atgttagata taagaaacta aattgaaata
      901 ttcaaacttg aatagtacca ggagaacaag tggaccaaaa tcttatacag ataatattac
      961 tttaattgaa ataaaaaata gatgtgtaac tttcaaaaaa aaaaaaaaaa a
//
