LOCUS       NM_026357               1652 bp    mRNA    linear   ROD 19-SEP-2024
DEFINITION  Mus musculus RIB43A domain with coiled-coils 2 (Ribc2), transcript
            variant 1, mRNA.
ACCESSION   NM_026357 XM_283290 XM_911372
VERSION     NM_026357.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1652)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 1652)
  AUTHORS   Tai,L., Yin,G., Huang,X., Sun,F. and Zhu,Y.
  TITLE     In-cell structural insight into the stability of sperm microtubule
            doublet
  JOURNAL   Cell Discov 9 (1), 116 (2023)
   PUBMED   37989994
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 1652)
  AUTHORS   Chen,Z., Shiozaki,M., Haas,K.M., Skinner,W.M., Zhao,S., Guo,C.,
            Polacco,B.J., Yu,Z., Krogan,N.J., Lishko,P.V., Kaake,R.M.,
            Vale,R.D. and Agard,D.A.
  TITLE     De novo protein identification in mammalian sperm using in situ
            cryoelectron tomography and AlphaFold2 docking
  JOURNAL   Cell 186 (23), 5041-5053 (2023)
   PUBMED   37865089
REFERENCE   4  (bases 1 to 1652)
  AUTHORS   Zhou,L., Liu,H., Liu,S., Yang,X., Dong,Y., Pan,Y., Xiao,Z.,
            Zheng,B., Sun,Y., Huang,P., Zhang,X., Hu,J., Sun,R., Feng,S.,
            Zhu,Y., Liu,M., Gui,M. and Wu,J.
  TITLE     Structures of sperm flagellar doublet microtubules expand the
            genetic spectrum of male infertility
  JOURNAL   Cell 186 (13), 2897-2910 (2023)
   PUBMED   37295417
REFERENCE   5  (bases 1 to 1652)
  AUTHORS   Arango,N.A., Pearson,E.J., Donahoe,P.K. and Teixeira,J.
  TITLE     Genomic structure and expression analysis of the mouse
            testis-specific ribbon protein (Trib) gene
  JOURNAL   Gene 343 (1), 221-227 (2004)
   PUBMED   15563848
  REMARK    GeneRIF: Genomic structure and expression profile of mouse Trib and
            comparison of its homology with other ribbon proteins.
            GeneRIF: Trib expression is testis-specific and appears to be found
            only in the germ cells during the leptotene-pachytene stages of
            spermatogenesis.
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BY716712.1 and AK016311.1.
            
            On or before Jun 24, 2009 this sequence version replaced
            XM_911372.2, XM_283290.4, NM_026357.1.
            
            Transcript Variant: This variant (1) represents the protein coding
            variant.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK016311.1, AK017028.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849384, SAMN01164133
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-20                BY716712.1         22-41
            21-1576             AK016311.1         22-1577
            1577-1652           AK016311.1         1579-1654
FEATURES             Location/Qualifiers
     source          1..1652
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="15"
                     /map="15 40.25 cM"
     gene            1..1652
                     /gene="Ribc2"
                     /gene_synonym="4930579A10Rik; Trib"
                     /note="RIB43A domain with coiled-coils 2"
                     /db_xref="GeneID:67747"
                     /db_xref="MGI:MGI:1914997"
     exon            1..282
                     /gene="Ribc2"
                     /gene_synonym="4930579A10Rik; Trib"
                     /inference="alignment:Splign:2.1.0"
     CDS             169..1302
                     /gene="Ribc2"
                     /gene_synonym="4930579A10Rik; Trib"
                     /note="testis-specific ribbon protein"
                     /codon_start=1
                     /product="RIB43A-like with coiled-coils protein 2"
                     /protein_id="NP_080633.2"
                     /db_xref="CCDS:CCDS49689.1"
                     /db_xref="GeneID:67747"
                     /db_xref="MGI:MGI:1914997"
                     /translation="MEVAMSKDLQQEANLAKKRYIDLCRQGRIFDARNRIIGGDTQAW
                     DFQVRDQKIKEITDKARHEAFAAEMKHNDKVMCMAHDREQRHRKQLCRAINDFQQNFQ
                     KPETRREFDLSDPLALQKELPARISDNDMRNTISGMQKFMGEDLNFQERRRFQKEQSR
                     EWFLQQHGEREKARADHLLAEHLHTQTRLKFDETARELMKLEGSTRKEVCAAVKAFNK
                     NQVVELTERKRQEKQQEQEDNMTEITNLLHGDLLSENPRPVASSFGSHRVVLDRWKGM
                     NREQLEEIWFTQKRQIQEKLRLQEEERQHSMDWDLRRIRKAHASLLHERQQQRLLREQ
                     RRALDCSNLNLARQQYLQKKQMNTASSSQPTEDYFSQFNTRSR"
     exon            283..364
                     /gene="Ribc2"
                     /gene_synonym="4930579A10Rik; Trib"
                     /inference="alignment:Splign:2.1.0"
     exon            365..709
                     /gene="Ribc2"
                     /gene_synonym="4930579A10Rik; Trib"
                     /inference="alignment:Splign:2.1.0"
     exon            710..828
                     /gene="Ribc2"
                     /gene_synonym="4930579A10Rik; Trib"
                     /inference="alignment:Splign:2.1.0"
     exon            829..1056
                     /gene="Ribc2"
                     /gene_synonym="4930579A10Rik; Trib"
                     /inference="alignment:Splign:2.1.0"
     exon            1057..1223
                     /gene="Ribc2"
                     /gene_synonym="4930579A10Rik; Trib"
                     /inference="alignment:Splign:2.1.0"
     exon            1224..1652
                     /gene="Ribc2"
                     /gene_synonym="4930579A10Rik; Trib"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1285..1290
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Ribc2"
                     /gene_synonym="4930579A10Rik; Trib"
                     /note="hexamer: AATACA"
     polyA_site      1311
                     /gene="Ribc2"
                     /gene_synonym="4930579A10Rik; Trib"
ORIGIN      
        1 aattggatcc ctgctccgct gcggaaagcg gaccgccggg acagacttgc tctcaaactt
       61 ttgtgggcgc tgcttctcgg cgctgtagct ttgcttattt ctgtgggctt ttcttgccgt
      121 gttttttttt tccggatagc tcctgaagcc cagccgagtc ccagagccat ggaggtagcg
      181 atgtctaagg acctacaaca ggaggccaac ctagccaaga agcggtacat tgacctgtgc
      241 aggcagggac ggatcttcga cgccaggaac aggatcattg ggggagacac acaagcctgg
      301 gattttcaag tccgtgacca gaagataaaa gaaataactg acaaagctag gcatgaagcc
      361 tttgctgctg aaatgaagca caatgacaaa gtcatgtgca tggcgcatga ccgggaacag
      421 aggcacagga aacagctgtg tagagctatc aatgacttcc agcagaactt tcagaagcca
      481 gaaactcgac gtgagtttga tctttctgac cccctggccc tccagaaaga gcttccagcc
      541 cgcatttcag acaatgacat gcggaacacc atatcaggaa tgcagaagtt catgggagag
      601 gatttaaact tccaagagag gaggaggttc caaaaggaac agagcagaga atggtttctg
      661 cagcagcatg gggaacggga gaaagcccgg gctgaccacc tactggcaga acacctccac
      721 actcagacga gactcaagtt tgatgaaaca gccagagagt tgatgaagct ggaaggctcc
      781 accaggaagg aagtctgcgc agccgtgaaa gcgttcaaca agaatcaggt tgtggagttg
      841 acagaaagaa agaggcaaga gaagcaacaa gaacaagaag acaacatgac cgagatcacc
      901 aacctgctgc atggagacct gctttctgag aaccctcgac cggtggccag ctcctttggg
      961 tctcaccgtg tggtccttga ccgctggaag ggcatgaacc gagagcagct ggaggagatc
     1021 tggttcacgc agaagcggca aatccaggag aagctgaggc ttcaggagga agagcgccag
     1081 cacagcatgg actgggattt gcgcaggatc cggaaggctc atgccagcct gctgcatgag
     1141 cggcagcagc agcgcttgct tcgggagcag cgcagggccc tggactgcag caacctcaac
     1201 ctggccaggc agcagtactt acagaaaaaa caaatgaata cagcctcctc aagtcagccc
     1261 acagaagact atttctcaca gtttaataca aggagccgct gagagaaccg actgctttcc
     1321 ttgtttatag tagttcctct aggagtcacg cttatttcaa agtgaatctg ctccttggtc
     1381 tgaacacccc gtatgggcat gtgcacatgc ggtcaggctc tgctctggga agagctctaa
     1441 catggctttg ggtgctgtgg acataggaca cagtgaacca ttccagagag gctacactga
     1501 ggcctgtgtg ctgctcaagc tccaagctgg ctgctcagcc attctctgac tcagtgactg
     1561 accatcatag gtgttgttcg tgtgccccat gaagcacttc ttcctcagct tctcacccac
     1621 cataaagagg caccaacctg cttaccactc cc
//
