LOCUS       NM_145530               1657 bp    mRNA    linear   ROD 01-JUN-2024
DEFINITION  Mus musculus ras homolog family member V (Rhov), mRNA.
ACCESSION   NM_145530
VERSION     NM_145530.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1657)
  AUTHORS   Garaffo,G., Provero,P., Molineris,I., Pinciroli,P., Peano,C.,
            Battaglia,C., Tomaiuolo,D., Etzion,T., Gothilf,Y., Santoro,M. and
            Merlo,G.R.
  TITLE     Profiling, Bioinformatic, and Functional Data on the Developing
            Olfactory/GnRH System Reveal Cellular and Molecular Pathways
            Essential for This Process and Potentially Relevant for the
            Kallmann Syndrome
  JOURNAL   Front Endocrinol (Lausanne) 4, 203 (2013)
   PUBMED   24427155
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1657)
  AUTHORS   Thompson,N., Gesina,E., Scheinert,P., Bucher,P. and
            Grapin-Botton,A.
  TITLE     RNA profiling and chromatin immunoprecipitation-sequencing reveal
            that PTF1a stabilizes pancreas progenitor identity via the control
            of MNX1/HLXB9 and a network of other transcription factors
  JOURNAL   Mol Cell Biol 32 (6), 1189-1199 (2012)
   PUBMED   22232429
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK037170.1 and AL929318.11.
            
            On Aug 25, 2009 this sequence version replaced NM_145530.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK037170.1, AK036775.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-1655              AK037170.1         3-1657
            1656-1657           AL929318.11        57017-57018         c
FEATURES             Location/Qualifiers
     source          1..1657
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="2"
                     /map="2 59.97 cM"
     gene            1..1657
                     /gene="Rhov"
                     /gene_synonym="A030005A06Rik; Arhv"
                     /note="ras homolog family member V"
                     /db_xref="GeneID:228543"
                     /db_xref="MGI:MGI:2444227"
     exon            1..311
                     /gene="Rhov"
                     /gene_synonym="A030005A06Rik; Arhv"
                     /inference="alignment:Splign:2.1.0"
     CDS             104..814
                     /gene="Rhov"
                     /gene_synonym="A030005A06Rik; Arhv"
                     /note="ras homolog gene family, member V"
                     /codon_start=1
                     /product="rho-related GTP-binding protein RhoV"
                     /protein_id="NP_663505.1"
                     /db_xref="CCDS:CCDS16598.1"
                     /db_xref="GeneID:228543"
                     /db_xref="MGI:MGI:2444227"
                     /translation="MPPRELSEAEPPPLPASTPPPRRRSAPPELGIKCVLVGDGAVGK
                     SSLIVSYTCNGYPARYRPTALDTFSVQVLVDGAPVRIELWDTAGQEDFDRLRSLCYPD
                     TDVFLACFSVVQPSSFQNITEKWLPEIRTHNPQAPVLLVGTQADLRDDVNVLIQLDQG
                     GREGPVPQPQAQGLAEKIRACCYLECSALTQKNLKEVFDSAILSAIEHKARLEKKLNA
                     KGVRTLSRCRWKKFFCFV"
     exon            312..370
                     /gene="Rhov"
                     /gene_synonym="A030005A06Rik; Arhv"
                     /inference="alignment:Splign:2.1.0"
     exon            371..1657
                     /gene="Rhov"
                     /gene_synonym="A030005A06Rik; Arhv"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1636..1641
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Rhov"
                     /gene_synonym="A030005A06Rik; Arhv"
                     /note="hexamer: AATAAA"
     polyA_site      1657
                     /gene="Rhov"
                     /gene_synonym="A030005A06Rik; Arhv"
                     /note="major polyA site"
ORIGIN      
        1 gcccagcttg gacagattgt cagcgtccgg ctgcggaacc tgcttccccg agtgccgcgg
       61 agcctggtcc gggctggccc ctctgctacc ccaggagcgg accatgccgc cgcgggagct
      121 aagcgaggcc gagccaccgc ctctcccggc ctcgacccct cctccgcggc ggcgcagcgc
      181 ccctccggag ctgggcatca aatgcgtgct ggtgggcgat ggcgcggtgg gcaagagcag
      241 cctcatcgtc agctacacct gcaatgggta ccccgcgcgc tatcggccta cagcactaga
      301 caccttctcc gtgcaagtcc tggtcgatgg agcccctgtg cgaatcgagc tttgggacac
      361 cgcagggcag gaggactttg accggcttcg ttctctctgc tacccggaca ccgatgtctt
      421 tctggcttgc ttcagcgtgg tgcagcccag ctccttccaa aacataacag aaaaatggct
      481 gcctgagatc cgcactcaca acccccaagc acccgtgttg ctggtgggca ctcaggctga
      541 cctaagggac gatgtcaatg tactaattca gttggaccaa ggaggccggg agggcccagt
      601 accacaaccc caagcccagg gtctggctga gaagatccgc gcctgctgct accttgagtg
      661 ctcggccttg acgcagaaga acttgaagga ggtgttcgac tcggccattc tcagtgcgat
      721 tgagcacaaa gcccgtctgg agaagaaact gaacgcaaaa ggtgtgcgca cgctgtctcg
      781 ctgtcgctgg aagaagttct tctgctttgt gtgagcagct atggcaagag ataggcgggt
      841 ggcctgagac ttctggaccc cgagacatcg ggtactggca gggcctggcc aacccctgga
      901 actcagttct ctattgaaca cagggcacat gggcctcaaa gctgtacacc ctggtgagcc
      961 agggtgagct ctgtctgtgc aggggctgcc ccatttggat ttctttggtc aagactcaca
     1021 ggaaaatccc agcactttga ttttcatggg atagcgccat cagcgtcagt gctgctgagc
     1081 agcttgggat gtaattctca gtttcttatc ctggggccac aggtcagttt ggctgaatgc
     1141 aggcccctcg gggtcatccc cctctcctag cacagtgcga ggatcaagga gaacagtggg
     1201 gcatcttgca gggctggcgg atggtcagct tgatttggag acgtttgaga tggggtatga
     1261 agaagagggc agtgagagat tgagagggaa aacagaaagt gaggcgagtg gtggacagga
     1321 ggcagattag aggcctgggc ctggaaggag gaagacagga agggagaagg gtggacagct
     1381 gtggagaagg ccgacacctg ggctgccctc gagccccaag gccagggagg acaggactgc
     1441 tccctgggaa gaactgggtc tcagggttcc ccaggcactg gccaaactgg ctgggctagc
     1501 agaggggcag gaagtgagag ttcaggccca gcaaagggag gggaggagct gcaggtagga
     1561 gcctgaagga ggaaggggca gggaccgtcc ctttccccaa ggtcatagct tagaaggtga
     1621 gctatacagt ctgcaaataa aaccttccat ttctcaa
//
