LOCUS       NM_001403472            5318 bp    mRNA    linear   ROD 13-FEB-2025
DEFINITION  Mus musculus regulator of G-protein signaling 12 (Rgs12),
            transcript variant 4, mRNA.
ACCESSION   NM_001403472 XM_006504123
VERSION     NM_001403472.1
KEYWORDS    RefSeq.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 5318)
  AUTHORS   Yuan,G., Yang,S. and Yang,S.
  TITLE     RGS12 represses oral squamous cell carcinoma by driving M1
            polarization of tumor-associated macrophages via controlling
            ciliary MYCBP2/KIF2A signaling
  JOURNAL   Int J Oral Sci 15 (1), 11 (2023)
   PUBMED   36797232
  REMARK    GeneRIF: RGS12 represses oral squamous cell carcinoma by driving M1
            polarization of tumor-associated macrophages via controlling
            ciliary MYCBP2/KIF2A signaling.
            Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5318)
  AUTHORS   Akturk,A., Day,M. and Tarchini,B.
  TITLE     RGS12 polarizes the GPSM2-GNAI complex to organize and elongate
            stereocilia in sensory hair cells
  JOURNAL   Sci Adv 8 (42), eabq2826 (2022)
   PUBMED   36260679
  REMARK    GeneRIF: RGS12 polarizes the GPSM2-GNAI complex to organize and
            elongate stereocilia in sensory hair cells.
REFERENCE   3  (bases 1 to 5318)
  AUTHORS   Li,Y., Liu,M., Yang,S., Fuller,A.M., Karin Eisinger-Mathason,T.S.
            and Yang,S.
  TITLE     RGS12 is a novel tumor suppressor in osteosarcoma that inhibits
            YAP-TEAD1-Ezrin signaling
  JOURNAL   Oncogene 40 (14), 2553-2566 (2021)
   PUBMED   33686240
REFERENCE   4  (bases 1 to 5318)
  AUTHORS   White,A.N., Gross,J.D., Kaski,S.W., Trexler,K.R., Wix,K.A.,
            Wetsel,W.C., Kinsey,S.G., Siderovski,D.P. and Setola,V.
  TITLE     Genetic deletion of Rgs12 in mice affects serotonin transporter
            expression and function in vivo and ex vivo
  JOURNAL   J Psychopharmacol 34 (12), 1393-1407 (2020)
   PUBMED   32842837
  REMARK    GeneRIF: Genetic deletion of Rgs12 in mice affects serotonin
            transporter expression and function in vivo and ex vivo.
REFERENCE   5  (bases 1 to 5318)
  AUTHORS   Yuan,G., Yang,S., Ng,A., Fu,C., Oursler,M.J., Xing,L. and Yang,S.
  TITLE     RGS12 Is a Novel Critical NF-kappaB Activator in Inflammatory
            Arthritis
  JOURNAL   iScience 23 (6), 101172 (2020)
   PUBMED   32512384
REFERENCE   6  (bases 1 to 5318)
  AUTHORS   Willard,M.D., Willard,F.S., Li,X., Cappell,S.D., Snider,W.D. and
            Siderovski,D.P.
  TITLE     Selective role for RGS12 as a Ras/Raf/MEK scaffold in nerve growth
            factor-mediated differentiation
  JOURNAL   EMBO J 26 (8), 2029-2040 (2007)
   PUBMED   17380122
REFERENCE   7  (bases 1 to 5318)
  AUTHORS   Yang,S. and Li,Y.P.
  TITLE     RGS12 is essential for RANKL-evoked signaling for terminal
            differentiation of osteoclasts in vitro
  JOURNAL   J Bone Miner Res 22 (1), 45-54 (2007)
   PUBMED   17042716
  REMARK    GeneRIF: RGS12 is essential for the terminal differentiation of
            osteoclasts induced by RANKL.
REFERENCE   8  (bases 1 to 5318)
  AUTHORS   Martin-McCaffrey,L., Hains,M.D., Pritchard,G.A., Pajak,A.,
            Dagnino,L., Siderovski,D.P. and D'Souza,S.J.
  TITLE     Differential expression of regulator of G-protein signaling R12
            subfamily members during mouse development
  JOURNAL   Dev Dyn 234 (2), 438-444 (2005)
   PUBMED   16145674
  REMARK    GeneRIF: RGS12 splice variants exhibit differential spatiotemporal
            patterns of expression during postimplantation embryogenesis,
            suggesting nonoverlapping roles
REFERENCE   9  (bases 1 to 5318)
  AUTHORS   Martin-McCaffrey,L., Willard,F.S., Oliveira-dos-Santos,A.J.,
            Natale,D.R., Snow,B.E., Kimple,R.J., Pajak,A., Watson,A.J.,
            Dagnino,L., Penninger,J.M., Siderovski,D.P. and D'Souza,S.J.
  TITLE     RGS14 is a mitotic spindle protein essential from the first
            division of the mammalian zygote
  JOURNAL   Dev Cell 7 (5), 763-769 (2004)
   PUBMED   15525537
REFERENCE   10 (bases 1 to 5318)
  AUTHORS   Sierra,D.A., Gilbert,D.J., Householder,D., Grishin,N.V., Yu,K.,
            Ukidwe,P., Barker,S.A., He,W., Wensel,T.G., Otero,G., Brown,G.,
            Copeland,N.G., Jenkins,N.A. and Wilkie,T.M.
  TITLE     Evolution of the regulators of G-protein signaling multigene family
            in mouse and human
  JOURNAL   Genomics 79 (2), 177-185 (2002)
   PUBMED   11829488
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC133204.3 and AC126447.3.
            
            On Mar 30, 2022 this sequence version replaced XM_006504123.4.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR9219380.82536.1,
                                           SRR10223969.5399.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-80                AC133204.3         3682-3761           c
            81-2063             AC126447.3         170273-172255       c
            2064-2180           AC126447.3         161695-161811       c
            2181-2202           AC126447.3         137799-137820       c
            2203-2372           AC126447.3         117516-117685       c
            2373-2465           AC126447.3         116622-116714       c
            2466-2609           AC126447.3         115769-115912       c
            2610-2789           AC126447.3         114257-114436       c
            2790-2943           AC126447.3         113846-113999       c
            2944-3020           AC126447.3         112675-112751       c
            3021-3215           AC126447.3         110985-111179       c
            3216-3289           AC126447.3         110627-110700       c
            3290-3416           AC126447.3         110039-110165       c
            3417-3513           AC126447.3         108396-108492       c
            3514-3593           AC126447.3         106938-107017       c
            3594-5318           AC126447.3         103433-105157       c
FEATURES             Location/Qualifiers
     source          1..5318
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="5"
                     /map="5 17.96 cM"
     gene            1..5318
                     /gene="Rgs12"
                     /gene_synonym="1200016K18Rik; 4632412M04Rik; E130309H11"
                     /note="regulator of G-protein signaling 12"
                     /db_xref="GeneID:71729"
                     /db_xref="MGI:MGI:1918979"
     exon            1..80
                     /gene="Rgs12"
                     /gene_synonym="1200016K18Rik; 4632412M04Rik; E130309H11"
                     /inference="alignment:Splign:2.1.0"
     exon            81..2063
                     /gene="Rgs12"
                     /gene_synonym="1200016K18Rik; 4632412M04Rik; E130309H11"
                     /inference="alignment:Splign:2.1.0"
     CDS             183..3656
                     /gene="Rgs12"
                     /gene_synonym="1200016K18Rik; 4632412M04Rik; E130309H11"
                     /note="isoform C is encoded by transcript variant 4"
                     /codon_start=1
                     /product="regulator of G-protein signaling 12 isoform C"
                     /protein_id="NP_001390401.1"
                     /db_xref="GeneID:71729"
                     /db_xref="MGI:MGI:1918979"
                     /translation="MYRAGEPGKRQPGPAPPRVRSVEVARGRAGYGFTLSGQAPCVLS
                     CVMRGSPADFVGLRAGDQILAINEINVKKASHEDVVKLIGKCSGVLHMVIAEGTSHVE
                     SCSSDEEGGLYEGKGWLRPKLDSKALGINRAERVVEEVQSGGIFNMIFESSSLCASGP
                     EPLKLKQRSLSESAALRLDAGQAGLCAPHPSMLSKEDISKVINDDSVFTVGLDSHDDF
                     GLDASILNVAMVVGYLGSIELPSTSSNLEHDSLQAIRGCMRRLRAEQKIHSLVTMKVM
                     HDCVQLVTDRAGVVAEYPAEKLAFSAVCPDDRRFFGLVTMQTNDDGGLAQEDEGALRT
                     SCHVFMVDPDLFHHKIHQGIARRFGFACTADPDTSGCLEFPASSLPVLQFISVLYRDM
                     GELIEGVRARAFLDGDADAHQNNSTSSNSDSGIGNFNQEEKSNRVLVVDLGGGSSRHG
                     QGSSPGWESGGGRGSQPWSAPWNGAFCHDSEAGSPLETSPNTDRFWDLTKHSGPVSHM
                     EVPPATLRSSIPPSKRGAAGSSCGFNQRWLPVHVLQEWQCGHASDQESYTDSTDGWSS
                     VNCGTLPPPMSKIPADRYRVEGSFAQAPLSTQKRDWSRKAFGMQNLFGPHRNVRKTKE
                     DKKSSKLGRGVALAQTSQRTSARRSFGRSRRFSITRSLDDLESATVSDGELTGADLKD
                     CISNNSLSSNASLPSVQSCRRLRERRVASWAVSFERLLQDPVGVRYFSDFLRKEFSEE
                     NILFWQACECFSHVPAHDKKELSYRAREIFSKFLCSKATTPVNIDSQAQLADDILNAP
                     HPDMFKEQQLQIFNLMKFDSYTRFLKSQLYQECVLAEVEGRTLPDSQQVPSSPASKHS
                     ISSDHSNVSTPKKLSGKSKSGRSLNEDVGEEDSEKKRRGAFFSWSRSRSTGRSQKKKD
                     HGDHAHDAPHANGGLCRRESQGSVSSAGSLDLSEACRTSALEKDKAAKHCCVHLPDGT
                     SCVVAVKSGFSIKEILSGLCERHGINGAAVDLFLVGGDKPLVLHQDSSILATRDLRLE
                     KRTLFRLDLVPINRSVGLKAKPTKPVTEVLRPVVAKYGLDLGSLLVRLSGEKEPLDLG
                     APISSLDGQRVILEERDPSRGKVSTDKQKGAPVKQNSAVNSSPRNHLAMSFLSSFPKL
                     RATEPMTSVGC"
     exon            2064..2180
                     /gene="Rgs12"
                     /gene_synonym="1200016K18Rik; 4632412M04Rik; E130309H11"
                     /inference="alignment:Splign:2.1.0"
     exon            2181..2202
                     /gene="Rgs12"
                     /gene_synonym="1200016K18Rik; 4632412M04Rik; E130309H11"
                     /inference="alignment:Splign:2.1.0"
     exon            2203..2372
                     /gene="Rgs12"
                     /gene_synonym="1200016K18Rik; 4632412M04Rik; E130309H11"
                     /inference="alignment:Splign:2.1.0"
     exon            2373..2465
                     /gene="Rgs12"
                     /gene_synonym="1200016K18Rik; 4632412M04Rik; E130309H11"
                     /inference="alignment:Splign:2.1.0"
     exon            2466..2609
                     /gene="Rgs12"
                     /gene_synonym="1200016K18Rik; 4632412M04Rik; E130309H11"
                     /inference="alignment:Splign:2.1.0"
     exon            2610..2789
                     /gene="Rgs12"
                     /gene_synonym="1200016K18Rik; 4632412M04Rik; E130309H11"
                     /inference="alignment:Splign:2.1.0"
     exon            2790..2943
                     /gene="Rgs12"
                     /gene_synonym="1200016K18Rik; 4632412M04Rik; E130309H11"
                     /inference="alignment:Splign:2.1.0"
     exon            2944..3020
                     /gene="Rgs12"
                     /gene_synonym="1200016K18Rik; 4632412M04Rik; E130309H11"
                     /inference="alignment:Splign:2.1.0"
     exon            3021..3215
                     /gene="Rgs12"
                     /gene_synonym="1200016K18Rik; 4632412M04Rik; E130309H11"
                     /inference="alignment:Splign:2.1.0"
     exon            3216..3289
                     /gene="Rgs12"
                     /gene_synonym="1200016K18Rik; 4632412M04Rik; E130309H11"
                     /inference="alignment:Splign:2.1.0"
     exon            3290..3416
                     /gene="Rgs12"
                     /gene_synonym="1200016K18Rik; 4632412M04Rik; E130309H11"
                     /inference="alignment:Splign:2.1.0"
     exon            3417..3513
                     /gene="Rgs12"
                     /gene_synonym="1200016K18Rik; 4632412M04Rik; E130309H11"
                     /inference="alignment:Splign:2.1.0"
     exon            3514..3593
                     /gene="Rgs12"
                     /gene_synonym="1200016K18Rik; 4632412M04Rik; E130309H11"
                     /inference="alignment:Splign:2.1.0"
     exon            3594..5318
                     /gene="Rgs12"
                     /gene_synonym="1200016K18Rik; 4632412M04Rik; E130309H11"
                     /inference="alignment:Splign:2.1.0"
     regulatory      5149..5154
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Rgs12"
                     /gene_synonym="1200016K18Rik; 4632412M04Rik; E130309H11"
                     /note="hexamer: AATAAA"
     polyA_site      5169
                     /gene="Rgs12"
                     /gene_synonym="1200016K18Rik; 4632412M04Rik; E130309H11"
                     /note="major polyA site"
     regulatory      5265..5270
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Rgs12"
                     /gene_synonym="1200016K18Rik; 4632412M04Rik; E130309H11"
                     /note="hexamer: AAGAAA"
     polyA_site      5308
                     /gene="Rgs12"
                     /gene_synonym="1200016K18Rik; 4632412M04Rik; E130309H11"
     polyA_site      5318
                     /gene="Rgs12"
                     /gene_synonym="1200016K18Rik; 4632412M04Rik; E130309H11"
ORIGIN      
        1 ggagccccgc ccccggcccg gcgacggcgg tgaccgttga tgctttcggc gggcgcccgg
       61 cgggagcaag cggcggcccg ggtaacattt caagacaaaa cccccagtag catcgtgcct
      121 tccttgaaac atggaatccg tggaatagtg ggacatgcga tcagccctga caatacagca
      181 ggatgtacag ggctggggag ccagggaaac ggcagcctgg ccctgcaccc cctcgagtgc
      241 ggagcgtcga agtggcccgg ggcagagctg gctacggctt caccctatca ggacaggcgc
      301 cctgtgtgct cagctgcgtc atgaggggca gccctgcaga tttcgtgggc ctccgggctg
      361 gggaccagat acttgccatc aacgaaatca acgtgaaaaa agcctcccat gaagatgtgg
      421 tgaaactgat cgggaaatgc tctggagtcc tgcacatggt gattgctgag ggcaccagtc
      481 atgtggagtc ctgttccagc gatgaagaag gtggcctgta tgaggggaaa ggctggctgc
      541 ggccaaaact tgattctaag gctttgggta taaacagggc agagagggtt gtggaagagg
      601 tccagtctgg tgggattttc aacatgattt ttgaaagctc aagtctttgt gccagtggcc
      661 ctgagccact gaagctgaag cagaggtcct tgtctgagtc ggctgctttg cggcttgatg
      721 ctggccaggc tggtctctgt gcaccacatc ccagcatgct ttccaaagaa gacatatcaa
      781 aagttatcaa tgatgattct gtattcactg tgggtctgga cagtcacgat gactttggac
      841 tagatgcgag tattttaaat gttgccatgg ttgtgggcta tttgggctcc attgagctcc
      901 cttccaccag ttccaacctg gagcatgaca gtttacaggc tatccgtggc tgcatgcgcc
      961 gcctacgggc tgagcagaag atccattccc tagtgaccat gaaggtcatg catgactgtg
     1021 tgcaactggt cactgacagg gctggcgtgg tggcagagta ccctgccgag aagctggcat
     1081 tcagtgcagt gtgcccggac gacaggcggt tcttcgggct agtgaccatg cagaccaatg
     1141 atgatggggg cctggcacag gaagatgaag gtgccctaag gacgtcctgc catgtgttca
     1201 tggtggaccc agacttattt catcacaaga tccaccaagg cattgcgcgg agatttgggt
     1261 ttgcatgcac tgcagaccca gacacgagtg gctgtttgga attcccagca tcttccctcc
     1321 ccgtgcttca gttcatctct gttctgtacc gagacatggg tgaactgatt gagggtgtgc
     1381 gggcccgtgc ctttctagat ggggatgcag atgcccacca gaataatagc actagcagca
     1441 acagtgacag cggcatcggc aatttcaacc aggaagagaa gagcaacagg gtgcttgtag
     1501 ttgacctggg tgggggctca agcaggcatg gccagggcag tagtccaggg tgggaaagtg
     1561 gaggtggaag gggctcacag ccttggagtg caccctggaa tggagctttc tgccatgact
     1621 cggaggctgg ctccccattg gaaaccagcc ccaacactga caggttctgg gacttaacaa
     1681 agcactcagg gcctgtctct cacatggagg tccctccagc caccttgagg agttctatac
     1741 ccccttctaa gaggggtgct gcaggttcca gctgtggttt caaccagagg tggctcccgg
     1801 tccatgtgct acaagagtgg cagtgtggac atgccagtga ccaggagtct tacacagact
     1861 ctactgacgg gtggtccagt gtcaactgtg gcacactgcc cccgcccatg agcaagatcc
     1921 ctgcagaccg ataccgggtg gagggcagct ttgctcaagc cccactgagt acccagaaga
     1981 gggactggtc taggaaggct ttcggaatgc agaacctttt tggaccccat cgaaatgtta
     2041 gaaagaccaa agaagacaaa aagagttcaa aattggggcg gggagttgcc ctggcccaga
     2101 cgtctcagcg cacctcagct cgcaggtcct ttggaagatc taggagattc agcatcacgc
     2161 gctcccttga tgatcttgag tctgcaactg tgtctgatgg tgagttgact ggagctgacc
     2221 ttaaggactg catcagcaac aacagcctga gcagcaatgc cagcctcccc agtgtgcaga
     2281 gctgccggcg cctacgagag aggagagttg caagctgggc agtgtcattt gagcgtctcc
     2341 ttcaggatcc tgttggtgtt cgctacttct ctgattttct acgtaaggaa ttcagtgaag
     2401 agaacatttt attctggcag gcctgtgagt gcttcagtca tgttcctgca catgacaaaa
     2461 aagagctctc ttacagggcc cgggagattt tcagtaaatt cctgtgcagc aaagccacca
     2521 ctcctgtcaa cattgacagc caggcccagc tggcagatga cattctcaat gcaccccacc
     2581 ctgacatgtt caaggaacaa cagctccaga ttttcaacct gatgaagttt gatagctaca
     2641 ctcgctttct gaaatcccag ctgtaccaag aatgcgtcct ggcagaggtg gagggacgta
     2701 ccctcccgga ctctcagcag gtccccagca gcccagcttc caagcacagc atcagctctg
     2761 accactccaa tgtgtccaca ccaaaaaagt taagtggaaa atcaaaatca ggacgatccc
     2821 tgaatgaaga tgttggggag gaggatagtg agaaaaaacg cagaggggcc tttttctctt
     2881 ggtcaaggag caggagcacg gggcggtccc agaagaagaa ggaccatggt gaccatgccc
     2941 atgatgcccc tcatgccaat ggaggcctct gccgtcggga gtcccaaggc tctgtatctt
     3001 ctgcggggag cctagacctg tcagaggcct gtaggacctc agcactcgag aaagataagg
     3061 ctgccaaaca ttgctgtgtc cacctcccag acgggacatc ctgtgtggtt gctgtcaagt
     3121 ccgggttctc catcaaagag attctgtctg gattgtgtga acggcatggc atcaatgggg
     3181 ctgctgtgga cctcttcctg gtgggcggag acaagcctct tgtgctgcat caggacagca
     3241 gcatcctggc caccagggac ctacgcttgg aaaagcggac tttgtttcgg ctggatctcg
     3301 ttccgattaa ccggtcagtg ggactcaagg ccaagcccac caagccagtc acggaagtgt
     3361 tgcggcccgt ggtggccaaa tatggcctgg acctgggtag cctgctggtg agactgagcg
     3421 gggagaagga gcccctggat cttggtgccc ctatctcaag tctggatgga caacgggtca
     3481 tcctagagga gagggatcct tctcgaggga aagtgtccac agacaaacag aaaggtgctc
     3541 ctgtcaaaca aaactcagct gtgaactcca gccccagaaa ccacttggct atgagttttt
     3601 tgagctcatt tccaaagctc agagcaacag agccgatgac cagcgtgggc tgctaaggaa
     3661 ggaagacctg gtgctgcccg agtttcttcg cttacctgct ggttcctcag aacttgccct
     3721 gtccagccca cccccagtca agggctatag caagagagct gttacaggcc atggccagga
     3781 gggagcagct cagacagagg agagctacag cgacagccca gctaccagcc ctgcctcagc
     3841 ccagagcccc tgctcagcct acagtccagg ctccgcccac agccccggct ccgcccacag
     3901 cacccctggg cctcctggga ccacccaacc tggagagaag cctacaaagc cctcctgtgt
     3961 ctccatggtg caagagggca ctacacaggc ctggaggagg ctatcaccag aaatggaggc
     4021 tgggggcatc cagactgtgg aggatgagca ggtggctgat ctgaccctga tgggggaggg
     4081 ggacatcagc agccccaaca gcacgctgct accaccaccc cccacacccc aagacacacc
     4141 aggacctcca agaccaggta cctccaggtt ctgactctac acctttgacc tgtccatgat
     4201 taataaaggg aacactgagg caggccgccc ctgctctaca gattctgtgg attgaaatgg
     4261 cctgaggaat ggcctccttc tcttatattt gtggggcctc ctttgccttt tctgaaagga
     4321 aagcaggtgg cagccaaggc tcagtctccc agggagggtc actgaggctc agacagatat
     4381 tccacgttga gctggtcctg tgaatgtgcc atgggaatgg tgagccacgc ccagtgaccc
     4441 cttgtgaagg ctcaggtctc tgagtgtgga tcttaccttt aaaacctgct tgctgccact
     4501 ttagcgtttt agcctcaaga tggaaaaaag tagtatttgt tttgagccag tcagcaaggg
     4561 tcccgtgctg acatggatca ggttctcagc gtcagcctct ctgtccagcc aggactcgct
     4621 gactgccctc cacactcggt agtgctcact ggctggcctc acgcgcgtcc aggcatttct
     4681 cttagtggaa gcatgaagtc ccgtgggtgt gaatggggac agtgtgaccg agtgttaggg
     4741 atgctactct agtcccaccc aaaacattca tgatcccaca caggtgacag ggctccggct
     4801 gtgttcagtg tcctcacagt gacagtgatg ggccttccag tgcatgttgc ttattgttcc
     4861 tgtctgacgc cttggctgtg atgcagcagg caatgtggcc gcccatctgg gtccagcttc
     4921 ctgggcctgg tcttttcagg cctcatgcat gtttcatgtg ctctcacaca ccatgggctg
     4981 gactccacag ccccacccag tgggcataca cccgatgggg aagcacaagg tgccatgaag
     5041 tggcgctgtg tgcatgcctg ggcacctctg tcaggccaca ccctcctttc tgctcctttg
     5101 tagctgcctg tttacagttc tgtgttctga ctctgttctt ccaagagaaa taaactctag
     5161 agctcaccac tggactggct ggaaactcct ttcttcttca cttgagggtg ggttttctct
     5221 ttaggattga agtacaggca tgtttctaca tcttaaccat tttaaagaaa ttatgtagat
     5281 ctaccttaaa caaccttttt aaaaatgatt atttaaaa
//
