LOCUS       NM_001403471            5476 bp    mRNA    linear   ROD 13-FEB-2025
DEFINITION  Mus musculus regulator of G-protein signaling 12 (Rgs12),
            transcript variant 3, mRNA.
ACCESSION   NM_001403471
VERSION     NM_001403471.1
KEYWORDS    RefSeq.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 5476)
  AUTHORS   Yuan,G., Yang,S. and Yang,S.
  TITLE     RGS12 represses oral squamous cell carcinoma by driving M1
            polarization of tumor-associated macrophages via controlling
            ciliary MYCBP2/KIF2A signaling
  JOURNAL   Int J Oral Sci 15 (1), 11 (2023)
   PUBMED   36797232
  REMARK    GeneRIF: RGS12 represses oral squamous cell carcinoma by driving M1
            polarization of tumor-associated macrophages via controlling
            ciliary MYCBP2/KIF2A signaling.
            Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5476)
  AUTHORS   Akturk,A., Day,M. and Tarchini,B.
  TITLE     RGS12 polarizes the GPSM2-GNAI complex to organize and elongate
            stereocilia in sensory hair cells
  JOURNAL   Sci Adv 8 (42), eabq2826 (2022)
   PUBMED   36260679
  REMARK    GeneRIF: RGS12 polarizes the GPSM2-GNAI complex to organize and
            elongate stereocilia in sensory hair cells.
REFERENCE   3  (bases 1 to 5476)
  AUTHORS   Li,Y., Liu,M., Yang,S., Fuller,A.M., Karin Eisinger-Mathason,T.S.
            and Yang,S.
  TITLE     RGS12 is a novel tumor suppressor in osteosarcoma that inhibits
            YAP-TEAD1-Ezrin signaling
  JOURNAL   Oncogene 40 (14), 2553-2566 (2021)
   PUBMED   33686240
REFERENCE   4  (bases 1 to 5476)
  AUTHORS   White,A.N., Gross,J.D., Kaski,S.W., Trexler,K.R., Wix,K.A.,
            Wetsel,W.C., Kinsey,S.G., Siderovski,D.P. and Setola,V.
  TITLE     Genetic deletion of Rgs12 in mice affects serotonin transporter
            expression and function in vivo and ex vivo
  JOURNAL   J Psychopharmacol 34 (12), 1393-1407 (2020)
   PUBMED   32842837
  REMARK    GeneRIF: Genetic deletion of Rgs12 in mice affects serotonin
            transporter expression and function in vivo and ex vivo.
REFERENCE   5  (bases 1 to 5476)
  AUTHORS   Yuan,G., Yang,S., Ng,A., Fu,C., Oursler,M.J., Xing,L. and Yang,S.
  TITLE     RGS12 Is a Novel Critical NF-kappaB Activator in Inflammatory
            Arthritis
  JOURNAL   iScience 23 (6), 101172 (2020)
   PUBMED   32512384
REFERENCE   6  (bases 1 to 5476)
  AUTHORS   Willard,M.D., Willard,F.S., Li,X., Cappell,S.D., Snider,W.D. and
            Siderovski,D.P.
  TITLE     Selective role for RGS12 as a Ras/Raf/MEK scaffold in nerve growth
            factor-mediated differentiation
  JOURNAL   EMBO J 26 (8), 2029-2040 (2007)
   PUBMED   17380122
REFERENCE   7  (bases 1 to 5476)
  AUTHORS   Yang,S. and Li,Y.P.
  TITLE     RGS12 is essential for RANKL-evoked signaling for terminal
            differentiation of osteoclasts in vitro
  JOURNAL   J Bone Miner Res 22 (1), 45-54 (2007)
   PUBMED   17042716
  REMARK    GeneRIF: RGS12 is essential for the terminal differentiation of
            osteoclasts induced by RANKL.
REFERENCE   8  (bases 1 to 5476)
  AUTHORS   Martin-McCaffrey,L., Hains,M.D., Pritchard,G.A., Pajak,A.,
            Dagnino,L., Siderovski,D.P. and D'Souza,S.J.
  TITLE     Differential expression of regulator of G-protein signaling R12
            subfamily members during mouse development
  JOURNAL   Dev Dyn 234 (2), 438-444 (2005)
   PUBMED   16145674
  REMARK    GeneRIF: RGS12 splice variants exhibit differential spatiotemporal
            patterns of expression during postimplantation embryogenesis,
            suggesting nonoverlapping roles
REFERENCE   9  (bases 1 to 5476)
  AUTHORS   Martin-McCaffrey,L., Willard,F.S., Oliveira-dos-Santos,A.J.,
            Natale,D.R., Snow,B.E., Kimple,R.J., Pajak,A., Watson,A.J.,
            Dagnino,L., Penninger,J.M., Siderovski,D.P. and D'Souza,S.J.
  TITLE     RGS14 is a mitotic spindle protein essential from the first
            division of the mammalian zygote
  JOURNAL   Dev Cell 7 (5), 763-769 (2004)
   PUBMED   15525537
REFERENCE   10 (bases 1 to 5476)
  AUTHORS   Sierra,D.A., Gilbert,D.J., Householder,D., Grishin,N.V., Yu,K.,
            Ukidwe,P., Barker,S.A., He,W., Wensel,T.G., Otero,G., Brown,G.,
            Copeland,N.G., Jenkins,N.A. and Wilkie,T.M.
  TITLE     Evolution of the regulators of G-protein signaling multigene family
            in mouse and human
  JOURNAL   Genomics 79 (2), 177-185 (2002)
   PUBMED   11829488
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC133204.3 and AC126447.3.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR10223970.7356.1,
                                           SRR9219380.49185.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-84                AC133204.3         3678-3761           c
            85-2067             AC126447.3         170273-172255       c
            2068-2184           AC126447.3         161695-161811       c
            2185-2206           AC126447.3         137799-137820       c
            2207-2376           AC126447.3         117516-117685       c
            2377-2469           AC126447.3         116622-116714       c
            2470-2613           AC126447.3         115769-115912       c
            2614-2793           AC126447.3         114257-114436       c
            2794-2947           AC126447.3         113846-113999       c
            2948-3024           AC126447.3         112675-112751       c
            3025-3219           AC126447.3         110985-111179       c
            3220-3293           AC126447.3         110627-110700       c
            3294-3420           AC126447.3         110039-110165       c
            3421-3517           AC126447.3         108396-108492       c
            3518-3597           AC126447.3         106938-107017       c
            3598-3751           AC126447.3         106407-106560       c
            3752-5476           AC126447.3         103433-105157       c
FEATURES             Location/Qualifiers
     source          1..5476
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="5"
                     /map="5 17.96 cM"
     gene            1..5476
                     /gene="Rgs12"
                     /gene_synonym="1200016K18Rik; 4632412M04Rik; E130309H11"
                     /note="regulator of G-protein signaling 12"
                     /db_xref="GeneID:71729"
                     /db_xref="MGI:MGI:1918979"
     exon            1..84
                     /gene="Rgs12"
                     /gene_synonym="1200016K18Rik; 4632412M04Rik; E130309H11"
                     /inference="alignment:Splign:2.1.0"
     exon            85..2067
                     /gene="Rgs12"
                     /gene_synonym="1200016K18Rik; 4632412M04Rik; E130309H11"
                     /inference="alignment:Splign:2.1.0"
     CDS             187..4332
                     /gene="Rgs12"
                     /gene_synonym="1200016K18Rik; 4632412M04Rik; E130309H11"
                     /note="isoform A is encoded by transcript variant 3"
                     /codon_start=1
                     /product="regulator of G-protein signaling 12 isoform A"
                     /protein_id="NP_001390400.1"
                     /db_xref="GeneID:71729"
                     /db_xref="MGI:MGI:1918979"
                     /translation="MYRAGEPGKRQPGPAPPRVRSVEVARGRAGYGFTLSGQAPCVLS
                     CVMRGSPADFVGLRAGDQILAINEINVKKASHEDVVKLIGKCSGVLHMVIAEGTSHVE
                     SCSSDEEGGLYEGKGWLRPKLDSKALGINRAERVVEEVQSGGIFNMIFESSSLCASGP
                     EPLKLKQRSLSESAALRLDAGQAGLCAPHPSMLSKEDISKVINDDSVFTVGLDSHDDF
                     GLDASILNVAMVVGYLGSIELPSTSSNLEHDSLQAIRGCMRRLRAEQKIHSLVTMKVM
                     HDCVQLVTDRAGVVAEYPAEKLAFSAVCPDDRRFFGLVTMQTNDDGGLAQEDEGALRT
                     SCHVFMVDPDLFHHKIHQGIARRFGFACTADPDTSGCLEFPASSLPVLQFISVLYRDM
                     GELIEGVRARAFLDGDADAHQNNSTSSNSDSGIGNFNQEEKSNRVLVVDLGGGSSRHG
                     QGSSPGWESGGGRGSQPWSAPWNGAFCHDSEAGSPLETSPNTDRFWDLTKHSGPVSHM
                     EVPPATLRSSIPPSKRGAAGSSCGFNQRWLPVHVLQEWQCGHASDQESYTDSTDGWSS
                     VNCGTLPPPMSKIPADRYRVEGSFAQAPLSTQKRDWSRKAFGMQNLFGPHRNVRKTKE
                     DKKSSKLGRGVALAQTSQRTSARRSFGRSRRFSITRSLDDLESATVSDGELTGADLKD
                     CISNNSLSSNASLPSVQSCRRLRERRVASWAVSFERLLQDPVGVRYFSDFLRKEFSEE
                     NILFWQACECFSHVPAHDKKELSYRAREIFSKFLCSKATTPVNIDSQAQLADDILNAP
                     HPDMFKEQQLQIFNLMKFDSYTRFLKSQLYQECVLAEVEGRTLPDSQQVPSSPASKHS
                     ISSDHSNVSTPKKLSGKSKSGRSLNEDVGEEDSEKKRRGAFFSWSRSRSTGRSQKKKD
                     HGDHAHDAPHANGGLCRRESQGSVSSAGSLDLSEACRTSALEKDKAAKHCCVHLPDGT
                     SCVVAVKSGFSIKEILSGLCERHGINGAAVDLFLVGGDKPLVLHQDSSILATRDLRLE
                     KRTLFRLDLVPINRSVGLKAKPTKPVTEVLRPVVAKYGLDLGSLLVRLSGEKEPLDLG
                     APISSLDGQRVILEERDPSRGKVSTDKQKGAPVKQNSAVNSSPRNHLAMGEERTLGKS
                     NSIKIRGENGKSARDPRLSKREESIAKIGKKKYQKINLDEAEEFFELISKAQSNRADD
                     QRGLLRKEDLVLPEFLRLPAGSSELALSSPPPVKGYSKRAVTGHGQEGAAQTEESYSD
                     SPATSPASAQSPCSAYSPGSAHSPGSAHSTPGPPGTTQPGEKPTKPSCVSMVQEGTTQ
                     AWRRLSPEMEAGGIQTVEDEQVADLTLMGEGDISSPNSTLLPPPPTPQDTPGPPRPGT
                     SRF"
     exon            2068..2184
                     /gene="Rgs12"
                     /gene_synonym="1200016K18Rik; 4632412M04Rik; E130309H11"
                     /inference="alignment:Splign:2.1.0"
     exon            2185..2206
                     /gene="Rgs12"
                     /gene_synonym="1200016K18Rik; 4632412M04Rik; E130309H11"
                     /inference="alignment:Splign:2.1.0"
     exon            2207..2376
                     /gene="Rgs12"
                     /gene_synonym="1200016K18Rik; 4632412M04Rik; E130309H11"
                     /inference="alignment:Splign:2.1.0"
     exon            2377..2469
                     /gene="Rgs12"
                     /gene_synonym="1200016K18Rik; 4632412M04Rik; E130309H11"
                     /inference="alignment:Splign:2.1.0"
     exon            2470..2613
                     /gene="Rgs12"
                     /gene_synonym="1200016K18Rik; 4632412M04Rik; E130309H11"
                     /inference="alignment:Splign:2.1.0"
     exon            2614..2793
                     /gene="Rgs12"
                     /gene_synonym="1200016K18Rik; 4632412M04Rik; E130309H11"
                     /inference="alignment:Splign:2.1.0"
     exon            2794..2947
                     /gene="Rgs12"
                     /gene_synonym="1200016K18Rik; 4632412M04Rik; E130309H11"
                     /inference="alignment:Splign:2.1.0"
     exon            2948..3024
                     /gene="Rgs12"
                     /gene_synonym="1200016K18Rik; 4632412M04Rik; E130309H11"
                     /inference="alignment:Splign:2.1.0"
     exon            3025..3219
                     /gene="Rgs12"
                     /gene_synonym="1200016K18Rik; 4632412M04Rik; E130309H11"
                     /inference="alignment:Splign:2.1.0"
     exon            3220..3293
                     /gene="Rgs12"
                     /gene_synonym="1200016K18Rik; 4632412M04Rik; E130309H11"
                     /inference="alignment:Splign:2.1.0"
     exon            3294..3420
                     /gene="Rgs12"
                     /gene_synonym="1200016K18Rik; 4632412M04Rik; E130309H11"
                     /inference="alignment:Splign:2.1.0"
     exon            3421..3517
                     /gene="Rgs12"
                     /gene_synonym="1200016K18Rik; 4632412M04Rik; E130309H11"
                     /inference="alignment:Splign:2.1.0"
     exon            3518..3597
                     /gene="Rgs12"
                     /gene_synonym="1200016K18Rik; 4632412M04Rik; E130309H11"
                     /inference="alignment:Splign:2.1.0"
     exon            3598..3751
                     /gene="Rgs12"
                     /gene_synonym="1200016K18Rik; 4632412M04Rik; E130309H11"
                     /inference="alignment:Splign:2.1.0"
     exon            3752..5476
                     /gene="Rgs12"
                     /gene_synonym="1200016K18Rik; 4632412M04Rik; E130309H11"
                     /inference="alignment:Splign:2.1.0"
     regulatory      5307..5312
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Rgs12"
                     /gene_synonym="1200016K18Rik; 4632412M04Rik; E130309H11"
                     /note="hexamer: AATAAA"
     polyA_site      5327
                     /gene="Rgs12"
                     /gene_synonym="1200016K18Rik; 4632412M04Rik; E130309H11"
                     /note="major polyA site"
     regulatory      5423..5428
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Rgs12"
                     /gene_synonym="1200016K18Rik; 4632412M04Rik; E130309H11"
                     /note="hexamer: AAGAAA"
     polyA_site      5466
                     /gene="Rgs12"
                     /gene_synonym="1200016K18Rik; 4632412M04Rik; E130309H11"
     polyA_site      5476
                     /gene="Rgs12"
                     /gene_synonym="1200016K18Rik; 4632412M04Rik; E130309H11"
ORIGIN      
        1 ggagccccgc ccccggcccg gcgacggcgg tgaccgttga tgctttcggc gggcgcccgg
       61 cgggagcaag cggcggcccg gtagggtaac atttcaagac aaaaccccca gtagcatcgt
      121 gccttccttg aaacatggaa tccgtggaat agtgggacat gcgatcagcc ctgacaatac
      181 agcaggatgt acagggctgg ggagccaggg aaacggcagc ctggccctgc accccctcga
      241 gtgcggagcg tcgaagtggc ccggggcaga gctggctacg gcttcaccct atcaggacag
      301 gcgccctgtg tgctcagctg cgtcatgagg ggcagccctg cagatttcgt gggcctccgg
      361 gctggggacc agatacttgc catcaacgaa atcaacgtga aaaaagcctc ccatgaagat
      421 gtggtgaaac tgatcgggaa atgctctgga gtcctgcaca tggtgattgc tgagggcacc
      481 agtcatgtgg agtcctgttc cagcgatgaa gaaggtggcc tgtatgaggg gaaaggctgg
      541 ctgcggccaa aacttgattc taaggctttg ggtataaaca gggcagagag ggttgtggaa
      601 gaggtccagt ctggtgggat tttcaacatg atttttgaaa gctcaagtct ttgtgccagt
      661 ggccctgagc cactgaagct gaagcagagg tccttgtctg agtcggctgc tttgcggctt
      721 gatgctggcc aggctggtct ctgtgcacca catcccagca tgctttccaa agaagacata
      781 tcaaaagtta tcaatgatga ttctgtattc actgtgggtc tggacagtca cgatgacttt
      841 ggactagatg cgagtatttt aaatgttgcc atggttgtgg gctatttggg ctccattgag
      901 ctcccttcca ccagttccaa cctggagcat gacagtttac aggctatccg tggctgcatg
      961 cgccgcctac gggctgagca gaagatccat tccctagtga ccatgaaggt catgcatgac
     1021 tgtgtgcaac tggtcactga cagggctggc gtggtggcag agtaccctgc cgagaagctg
     1081 gcattcagtg cagtgtgccc ggacgacagg cggttcttcg ggctagtgac catgcagacc
     1141 aatgatgatg ggggcctggc acaggaagat gaaggtgccc taaggacgtc ctgccatgtg
     1201 ttcatggtgg acccagactt atttcatcac aagatccacc aaggcattgc gcggagattt
     1261 gggtttgcat gcactgcaga cccagacacg agtggctgtt tggaattccc agcatcttcc
     1321 ctccccgtgc ttcagttcat ctctgttctg taccgagaca tgggtgaact gattgagggt
     1381 gtgcgggccc gtgcctttct agatggggat gcagatgccc accagaataa tagcactagc
     1441 agcaacagtg acagcggcat cggcaatttc aaccaggaag agaagagcaa cagggtgctt
     1501 gtagttgacc tgggtggggg ctcaagcagg catggccagg gcagtagtcc agggtgggaa
     1561 agtggaggtg gaaggggctc acagccttgg agtgcaccct ggaatggagc tttctgccat
     1621 gactcggagg ctggctcccc attggaaacc agccccaaca ctgacaggtt ctgggactta
     1681 acaaagcact cagggcctgt ctctcacatg gaggtccctc cagccacctt gaggagttct
     1741 ataccccctt ctaagagggg tgctgcaggt tccagctgtg gtttcaacca gaggtggctc
     1801 ccggtccatg tgctacaaga gtggcagtgt ggacatgcca gtgaccagga gtcttacaca
     1861 gactctactg acgggtggtc cagtgtcaac tgtggcacac tgcccccgcc catgagcaag
     1921 atccctgcag accgataccg ggtggagggc agctttgctc aagccccact gagtacccag
     1981 aagagggact ggtctaggaa ggctttcgga atgcagaacc tttttggacc ccatcgaaat
     2041 gttagaaaga ccaaagaaga caaaaagagt tcaaaattgg ggcggggagt tgccctggcc
     2101 cagacgtctc agcgcacctc agctcgcagg tcctttggaa gatctaggag attcagcatc
     2161 acgcgctccc ttgatgatct tgagtctgca actgtgtctg atggtgagtt gactggagct
     2221 gaccttaagg actgcatcag caacaacagc ctgagcagca atgccagcct ccccagtgtg
     2281 cagagctgcc ggcgcctacg agagaggaga gttgcaagct gggcagtgtc atttgagcgt
     2341 ctccttcagg atcctgttgg tgttcgctac ttctctgatt ttctacgtaa ggaattcagt
     2401 gaagagaaca ttttattctg gcaggcctgt gagtgcttca gtcatgttcc tgcacatgac
     2461 aaaaaagagc tctcttacag ggcccgggag attttcagta aattcctgtg cagcaaagcc
     2521 accactcctg tcaacattga cagccaggcc cagctggcag atgacattct caatgcaccc
     2581 caccctgaca tgttcaagga acaacagctc cagattttca acctgatgaa gtttgatagc
     2641 tacactcgct ttctgaaatc ccagctgtac caagaatgcg tcctggcaga ggtggaggga
     2701 cgtaccctcc cggactctca gcaggtcccc agcagcccag cttccaagca cagcatcagc
     2761 tctgaccact ccaatgtgtc cacaccaaaa aagttaagtg gaaaatcaaa atcaggacga
     2821 tccctgaatg aagatgttgg ggaggaggat agtgagaaaa aacgcagagg ggcctttttc
     2881 tcttggtcaa ggagcaggag cacggggcgg tcccagaaga agaaggacca tggtgaccat
     2941 gcccatgatg cccctcatgc caatggaggc ctctgccgtc gggagtccca aggctctgta
     3001 tcttctgcgg ggagcctaga cctgtcagag gcctgtagga cctcagcact cgagaaagat
     3061 aaggctgcca aacattgctg tgtccacctc ccagacggga catcctgtgt ggttgctgtc
     3121 aagtccgggt tctccatcaa agagattctg tctggattgt gtgaacggca tggcatcaat
     3181 ggggctgctg tggacctctt cctggtgggc ggagacaagc ctcttgtgct gcatcaggac
     3241 agcagcatcc tggccaccag ggacctacgc ttggaaaagc ggactttgtt tcggctggat
     3301 ctcgttccga ttaaccggtc agtgggactc aaggccaagc ccaccaagcc agtcacggaa
     3361 gtgttgcggc ccgtggtggc caaatatggc ctggacctgg gtagcctgct ggtgagactg
     3421 agcggggaga aggagcccct ggatcttggt gcccctatct caagtctgga tggacaacgg
     3481 gtcatcctag aggagaggga tccttctcga gggaaagtgt ccacagacaa acagaaaggt
     3541 gctcctgtca aacaaaactc agctgtgaac tccagcccca gaaaccactt ggctatggga
     3601 gaggagagaa cactaggcaa gtctaactct attaaaataa gaggagaaaa tggaaaaagt
     3661 gctagggatc cccgcctttc aaagagagaa gaatctattg caaagattgg gaaaaaaaaa
     3721 tatcagaaaa ttaatttgga cgaagcagag gagttttttg agctcatttc caaagctcag
     3781 agcaacagag ccgatgacca gcgtgggctg ctaaggaagg aagacctggt gctgcccgag
     3841 tttcttcgct tacctgctgg ttcctcagaa cttgccctgt ccagcccacc cccagtcaag
     3901 ggctatagca agagagctgt tacaggccat ggccaggagg gagcagctca gacagaggag
     3961 agctacagcg acagcccagc taccagccct gcctcagccc agagcccctg ctcagcctac
     4021 agtccaggct ccgcccacag ccccggctcc gcccacagca cccctgggcc tcctgggacc
     4081 acccaacctg gagagaagcc tacaaagccc tcctgtgtct ccatggtgca agagggcact
     4141 acacaggcct ggaggaggct atcaccagaa atggaggctg ggggcatcca gactgtggag
     4201 gatgagcagg tggctgatct gaccctgatg ggggaggggg acatcagcag ccccaacagc
     4261 acgctgctac caccaccccc cacaccccaa gacacaccag gacctccaag accaggtacc
     4321 tccaggttct gactctacac ctttgacctg tccatgatta ataaagggaa cactgaggca
     4381 ggccgcccct gctctacaga ttctgtggat tgaaatggcc tgaggaatgg cctccttctc
     4441 ttatatttgt ggggcctcct ttgccttttc tgaaaggaaa gcaggtggca gccaaggctc
     4501 agtctcccag ggagggtcac tgaggctcag acagatattc cacgttgagc tggtcctgtg
     4561 aatgtgccat gggaatggtg agccacgccc agtgacccct tgtgaaggct caggtctctg
     4621 agtgtggatc ttacctttaa aacctgcttg ctgccacttt agcgttttag cctcaagatg
     4681 gaaaaaagta gtatttgttt tgagccagtc agcaagggtc ccgtgctgac atggatcagg
     4741 ttctcagcgt cagcctctct gtccagccag gactcgctga ctgccctcca cactcggtag
     4801 tgctcactgg ctggcctcac gcgcgtccag gcatttctct tagtggaagc atgaagtccc
     4861 gtgggtgtga atggggacag tgtgaccgag tgttagggat gctactctag tcccacccaa
     4921 aacattcatg atcccacaca ggtgacaggg ctccggctgt gttcagtgtc ctcacagtga
     4981 cagtgatggg ccttccagtg catgttgctt attgttcctg tctgacgcct tggctgtgat
     5041 gcagcaggca atgtggccgc ccatctgggt ccagcttcct gggcctggtc ttttcaggcc
     5101 tcatgcatgt ttcatgtgct ctcacacacc atgggctgga ctccacagcc ccacccagtg
     5161 ggcatacacc cgatggggaa gcacaaggtg ccatgaagtg gcgctgtgtg catgcctggg
     5221 cacctctgtc aggccacacc ctcctttctg ctcctttgta gctgcctgtt tacagttctg
     5281 tgttctgact ctgttcttcc aagagaaata aactctagag ctcaccactg gactggctgg
     5341 aaactccttt cttcttcact tgagggtggg ttttctcttt aggattgaag tacaggcatg
     5401 tttctacatc ttaaccattt taaagaaatt atgtagatct accttaaaca acctttttaa
     5461 aaatgattat ttaaaa
//
