LOCUS       NM_023622               2550 bp    mRNA    linear   ROD 16-FEB-2024
DEFINITION  Mus musculus ral guanine nucleotide dissociation stimulator-like 3
            (Rgl3), mRNA.
ACCESSION   NM_023622
VERSION     NM_023622.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2550)
  AUTHORS   Xu,J., Shi,S., Matsumoto,N., Noda,M. and Kitayama,H.
  TITLE     Identification of Rgl3 as a potential binding partner for
            Rap-family small G-proteins and profilin II
  JOURNAL   Cell Signal 19 (7), 1575-1582 (2007)
   PUBMED   17382517
  REMARK    GeneRIF: These findings raise the possibility that Rgl3 mediates
            interaction between Ras/Rap-family proteins and profilin II, an
            important activator of actin polymerization.
REFERENCE   2  (bases 1 to 2550)
  AUTHORS   Okazaki,N., Kikuno,R., Ohara,R., Inamoto,S., Koseki,H., Hiraoka,S.,
            Saga,Y., Kitamura,H., Nakagawa,T., Nagase,T., Ohara,O. and Koga,H.
  TITLE     Prediction of the coding sequences of mouse homologues of FLJ
            genes: the complete nucleotide sequences of 110 mouse
            FLJ-homologous cDnas identified by screening of terminal sequences
            of cDNA clones randomly sampled from size-fractionated libraries
  JOURNAL   DNA Res 11 (2), 127-135 (2004)
   PUBMED   15449545
REFERENCE   3  (bases 1 to 2550)
  AUTHORS   Ehrhardt,G.R., Korherr,C., Wieler,J.S., Knaus,M. and Schrader,J.W.
  TITLE     A novel potential effector of M-Ras and p21 Ras negatively
            regulates p21 Ras-mediated gene induction and cell growth
  JOURNAL   Oncogene 20 (2), 188-197 (2001)
   PUBMED   11313946
REFERENCE   4  (bases 1 to 2550)
  AUTHORS   Shao,H. and Andres,D.A.
  TITLE     A novel RalGEF-like protein, RGL3, as a candidate effector for rit
            and Ras
  JOURNAL   J Biol Chem 275 (35), 26914-26924 (2000)
   PUBMED   10869344
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AC163623.5.
            
            [WARNING] On Apr 10, 2024 this sequence was replaced by
            NM_023622.5.
            
            On Apr 30, 2007 this sequence version replaced NM_023622.3.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AF239661.1, AK053550.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN00849374,
                                           SAMN00849375 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-89                AC163623.5         55507-55595         c
            90-200              AC163623.5         54991-55101         c
            201-430             AC163623.5         54188-54417         c
            431-484             AC163623.5         53993-54046         c
            485-699             AC163623.5         53641-53855         c
            700-839             AC163623.5         47746-47885         c
            840-1055            AC163623.5         47432-47647         c
            1056-1159           AC163623.5         46826-46929         c
            1160-1244           AC163623.5         46644-46728         c
            1245-1292           AC163623.5         43524-43571         c
            1293-1379           AC163623.5         43332-43418         c
            1380-1412           AC163623.5         43087-43119         c
            1413-1534           AC163623.5         42881-43002         c
            1535-1630           AC163623.5         42092-42187         c
            1631-1699           AC163623.5         41934-42002         c
            1700-1799           AC163623.5         41750-41849         c
            1800-1952           AC163623.5         40530-40682         c
            1953-2067           AC163623.5         40164-40278         c
            2068-2550           AC163623.5         37669-38151         c
FEATURES             Location/Qualifiers
     source          1..2550
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="9"
                     /map="9 7.96 cM"
     gene            1..2550
                     /gene="Rgl3"
                     /gene_synonym="1300003D20Rik; mFLJ00153"
                     /note="ral guanine nucleotide dissociation stimulator-like
                     3"
                     /db_xref="GeneID:71746"
                     /db_xref="MGI:MGI:1918996"
     exon            1..89
                     /gene="Rgl3"
                     /gene_synonym="1300003D20Rik; mFLJ00153"
                     /inference="alignment:Splign:2.1.0"
     CDS             57..2186
                     /gene="Rgl3"
                     /gene_synonym="1300003D20Rik; mFLJ00153"
                     /note="Ral guanine-nucleotide exchange factor; RalGDS-like
                     protein 3; RPM; ralGDS-like 3; ras pathway modulator;
                     ralGDS-related effector protein of M-Ras"
                     /codon_start=1
                     /product="ral guanine nucleotide dissociation
                     stimulator-like 3"
                     /protein_id="NP_076111.2"
                     /db_xref="CCDS:CCDS22916.1"
                     /db_xref="GeneID:71746"
                     /db_xref="MGI:MGI:1918996"
                     /translation="MERTAGKELALAPLQDWGEETEDGAVYSVSLRRQRSQRSTPERS
                     GEGQTPIPATDTFLHYRTSKVRALRAARLERLVHELVSGDREQDPGFVPAFLATHRAF
                     VPTARVLGFLLPPPPPPPPPPAGVDSKRTEGQDLNFSKNLRAVVSVLGSWLRNHPQDF
                     RDPPDHQNLGNVRIFLGWAAPGGAEAREAEKLLEDFLKEAKGEQTEEEKRLAWSGPPR
                     IAQTPGSEFAEDCVEEEGPSSEGPELLDFSVDDVAEQLTLMDVELFLRVRSCECLGSM
                     WSQRDRPGAAGISPTVRATVAQFNTVTGCVLGSVLAAPGLAASQRAQRIEKWIRIAQR
                     CRELRNFSSLRAILSALQSNPIYRLKRSWGAVSREPLSVFRKLSQIFSDEDNHLSSRA
                     ILSQEETTEDDDCPSGSLPSKLPPGPVPYLGTFLTDLVMLDTALPDTLKGNLINFEKR
                     RKEWEILARIQQLQQRCQRYSLSPRPPILAALRAQRQLSEEQSYRVSRVIEPPAASCP
                     SSPRIRRRISLTKRLSAKLSREKNSSPGGSPGDPSSPTSSVSPGSPPSSPRNREPPPP
                     GSPPASPGPQSPSTKLSLTMDPPGPWPVTLTPSSSRVPLLGQQTSEARVIRVSINNNH
                     GNLYRSILLTCQDKAPSVVQRALEKHNVPQPWARDYQLFQVLPGDRELLIPDGANVFY
                     AMSPAAPGDFLLRRKEGTGHTLSASPT"
     exon            90..200
                     /gene="Rgl3"
                     /gene_synonym="1300003D20Rik; mFLJ00153"
                     /inference="alignment:Splign:2.1.0"
     exon            201..430
                     /gene="Rgl3"
                     /gene_synonym="1300003D20Rik; mFLJ00153"
                     /inference="alignment:Splign:2.1.0"
     exon            431..484
                     /gene="Rgl3"
                     /gene_synonym="1300003D20Rik; mFLJ00153"
                     /inference="alignment:Splign:2.1.0"
     exon            485..699
                     /gene="Rgl3"
                     /gene_synonym="1300003D20Rik; mFLJ00153"
                     /inference="alignment:Splign:2.1.0"
     exon            700..839
                     /gene="Rgl3"
                     /gene_synonym="1300003D20Rik; mFLJ00153"
                     /inference="alignment:Splign:2.1.0"
     exon            840..1055
                     /gene="Rgl3"
                     /gene_synonym="1300003D20Rik; mFLJ00153"
                     /inference="alignment:Splign:2.1.0"
     exon            1056..1159
                     /gene="Rgl3"
                     /gene_synonym="1300003D20Rik; mFLJ00153"
                     /inference="alignment:Splign:2.1.0"
     exon            1160..1244
                     /gene="Rgl3"
                     /gene_synonym="1300003D20Rik; mFLJ00153"
                     /inference="alignment:Splign:2.1.0"
     exon            1245..1292
                     /gene="Rgl3"
                     /gene_synonym="1300003D20Rik; mFLJ00153"
                     /inference="alignment:Splign:2.1.0"
     exon            1293..1379
                     /gene="Rgl3"
                     /gene_synonym="1300003D20Rik; mFLJ00153"
                     /inference="alignment:Splign:2.1.0"
     exon            1380..1412
                     /gene="Rgl3"
                     /gene_synonym="1300003D20Rik; mFLJ00153"
                     /inference="alignment:Splign:2.1.0"
     exon            1413..1534
                     /gene="Rgl3"
                     /gene_synonym="1300003D20Rik; mFLJ00153"
                     /inference="alignment:Splign:2.1.0"
     exon            1535..1630
                     /gene="Rgl3"
                     /gene_synonym="1300003D20Rik; mFLJ00153"
                     /inference="alignment:Splign:2.1.0"
     exon            1631..1699
                     /gene="Rgl3"
                     /gene_synonym="1300003D20Rik; mFLJ00153"
                     /inference="alignment:Splign:2.1.0"
     exon            1700..1799
                     /gene="Rgl3"
                     /gene_synonym="1300003D20Rik; mFLJ00153"
                     /inference="alignment:Splign:2.1.0"
     exon            1800..1952
                     /gene="Rgl3"
                     /gene_synonym="1300003D20Rik; mFLJ00153"
                     /inference="alignment:Splign:2.1.0"
     exon            1953..2067
                     /gene="Rgl3"
                     /gene_synonym="1300003D20Rik; mFLJ00153"
                     /inference="alignment:Splign:2.1.0"
     exon            2068..2550
                     /gene="Rgl3"
                     /gene_synonym="1300003D20Rik; mFLJ00153"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 cgctggccct tccgcttcac tcagcggcgc cagggagcag gacgggcacc ggggccatgg
       61 agaggacagc gggcaaagag ctggccctgg cgccgctgca ggactggggc gaggagaccg
      121 aggatggcgc cgtgtacagc gtctccctgc ggcggcagcg cagccagcgc tcgaccccag
      181 agaggtctgg agaaggccag acccccatcc cggctaccga caccttcctt cattaccgaa
      241 ccagcaaggt gcgggcgctg agggccgccc gactggagcg gctggtgcat gagttggtgt
      301 ccggagaccg cgagcaggat cctggcttcg tgcctgcctt cctggccacc caccgggcct
      361 ttgtacccac agcccgcgtt ttgggttttc tgctaccccc gccaccgccg ccgccaccac
      421 ctcctgctgg ggtagacagc aagaggacag agggacaaga tctgaacttc agcaagaacc
      481 tgagggctgt agtttcggtg ctgggttctt ggctgcgaaa tcatcctcag gacttccggg
      541 atccccctga tcatcagaac ctaggcaatg tccgaatctt tttgggctgg gcagccccag
      601 gaggggcaga agccagggaa gcagagaaac ttctagaaga tttcttgaag gaggctaagg
      661 gagagcagac agaggaggaa aagcgactgg cttggtcagg ccctcctagg attgcccaga
      721 cccccggatc ggagtttgcg gaggactgtg tggaagagga aggccccagt tcagaaggcc
      781 cagagctcct ggacttcagc gtggatgacg tggcagagca gctgaccctt atggatgtgg
      841 agctcttctt gcgcgtgagg tcctgcgaat gcctgggttc catgtggtct cagcgcgacc
      901 ggccaggagc tgcaggcatc tctcccacag tgcgtgccac cgtagcccag ttcaatacgg
      961 tgaccggctg cgtgctgggc tcggtgctcg ctgcgcccgg cctggcggcc tcgcagaggg
     1021 cacagcgcat cgaaaaatgg attcgcatcg cccagcggtg cagggaacta cgaaatttct
     1081 cttcattgcg agcgatcctg tccgccctgc aatctaaccc catctacaga ctcaagcgca
     1141 gctggggagc tgtgagccgg gaaccgctgt ctgttttcag gaaactgtca cagatttttt
     1201 ctgatgagga taaccatctc agcagccgag cgattctttc ccaggaggag accactgagg
     1261 atgatgactg cccctcagga agtctgccat caaaactgcc cccgggtcct gtcccctacc
     1321 ttggcacctt cctcacagac ttggttatgc tggatacagc cttaccggat acgttgaagg
     1381 gaaacctcat caactttgaa aagaggagga aggagtggga gatcctggcc cgaatccagc
     1441 agctacagca acgctgccag cgctacagcc tgagcccccg cccgccaatc ctggctgcac
     1501 ttcgagccca gcgccagctc agcgaggagc aaagctaccg agtctcccgt gttattgagc
     1561 caccagctgc ctcctgtccc agctcccctc gtatccggcg acgcatcagc ctcacaaagc
     1621 gtctcagtgc gaagctgtcc cgagagaaga actcatctcc tggcgggagt cccggggatc
     1681 cgtcctcacc tacctccagt gtgtctccag gttcaccccc atccagccct agaaaccgag
     1741 agcctcctcc tccgggcagt cctccagcct ccccagggcc tcagagcccc agcaccaagc
     1801 tctccctgac catggaccca ccagggccct ggcccgtgac cttgactccg agcagctccc
     1861 gagttcccct cctcgggcag cagacgtcag aggcccgcgt catcagagtc agcatcaaca
     1921 ataaccacgg gaacctgtat cggagcatct tgcttacttg tcaggacaaa gcccccagcg
     1981 tggtgcaaag agccctggag aagcacaatg tgccccagcc ctgggcccgt gactaccagc
     2041 tcttccaggt cctgcctggg gacagagagc tcctgattcc agacggtgcc aacgtcttct
     2101 acgctatgag cccagctgcc cctggtgact tcttgcttcg tcggaaagag gggacaggac
     2161 atacactgtc tgcctcccca acctgaggtg gtgctctcct tgttctgggc cagaggcaca
     2221 gctgatagct tggaacttgg attctactac tatcaaagta ggggcctatt ttctggagag
     2281 cctccacccc cactcatgga agctattttg ctctgtaccc cggggatccc cagcattagg
     2341 ccattggacc ccatctctct gactccctga gcccctccct gcccattatt ctaagaccat
     2401 ggatgtgtga ggagagtgta aaactaggaa aaattaagaa cccatagagc tgggagctta
     2461 gcttaggtgg gcgagcacct gcctagcagg ccccagaccc tggatggttt ctcagcactt
     2521 ctaaaaataa aagtcttcag gggttttgca
//
