LOCUS       NM_001346117            5093 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus ral guanine nucleotide dissociation stimulator,-like 1
            (Rgl1), transcript variant 1, mRNA.
ACCESSION   NM_001346117
VERSION     NM_001346117.1
KEYWORDS    RefSeq.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 5093)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 5093)
  AUTHORS   Gentry,L.R., Martin,T.D., Reiner,D.J. and Der,C.J.
  TITLE     Ral small GTPase signaling and oncogenesis: More than just
            15minutes of fame
  JOURNAL   Biochim Biophys Acta 1843 (12), 2976-2988 (2014)
   PUBMED   25219551
  REMARK    Review article
REFERENCE   3  (bases 1 to 5093)
  AUTHORS   Kirkby,N.S., Lundberg,M.H., Wright,W.R., Warner,T.D.,
            Paul-Clark,M.J. and Mitchell,J.A.
  TITLE     COX-2 protects against atherosclerosis independently of local
            vascular prostacyclin: identification of COX-2 associated pathways
            implicate Rgl1 and lymphocyte networks
  JOURNAL   PLoS One 9 (6), e98165 (2014)
   PUBMED   24887395
  REMARK    GeneRIF: rgl1 expression was strongly reduced by COX-2 deletion
            across all examined tissues.
            Publication Status: Online-Only
REFERENCE   4  (bases 1 to 5093)
  AUTHORS   Cooper,J.M., Bodemann,B.O. and White,M.A.
  TITLE     The RalGEF/Ral pathway: evaluating an intervention opportunity for
            Ras cancers
  JOURNAL   Enzymes 34 Pt. B, 137-156 (2013)
   PUBMED   25034103
  REMARK    Review article
REFERENCE   5  (bases 1 to 5093)
  AUTHORS   Ferro,E. and Trabalzini,L.
  TITLE     RalGDS family members couple Ras to Ral signalling and that's not
            all
  JOURNAL   Cell Signal 22 (12), 1804-1810 (2010)
   PUBMED   20478380
  REMARK    Review article
REFERENCE   6  (bases 1 to 5093)
  AUTHORS   Okazaki,N., F-Kikuno,R., Ohara,R., Inamoto,S., Koseki,H.,
            Hiraoka,S., Saga,Y., Seino,S., Nishimura,M., Kaisho,T., Hoshino,K.,
            Kitamura,H., Nagase,T., Ohara,O. and Koga,H.
  TITLE     Prediction of the coding sequences of mouse homologues of KIAA
            gene: IV. The complete nucleotide sequences of 500 mouse
            KIAA-homologous cDNAs identified by screening of terminal sequences
            of cDNA clones randomly sampled from size-fractionated libraries
  JOURNAL   DNA Res 11 (3), 205-218 (2004)
   PUBMED   15368895
REFERENCE   7  (bases 1 to 5093)
  AUTHORS   Sharov,A.A., Piao,Y., Matoba,R., Dudekula,D.B., Qian,Y.,
            VanBuren,V., Falco,G., Martin,P.R., Stagg,C.A., Bassey,U.C.,
            Wang,Y., Carter,M.G., Hamatani,T., Aiba,K., Akutsu,H., Sharova,L.,
            Tanaka,T.S., Kimber,W.L., Yoshikawa,T., Jaradat,S.A., Pantano,S.,
            Nagaraja,R., Boheler,K.R., Taub,D., Hodes,R.J., Longo,D.L.,
            Schlessinger,D., Keller,J., Klotz,E., Kelsoe,G., Umezawa,A.,
            Vescovi,A.L., Rossant,J., Kunath,T., Hogan,B.L., Curci,A.,
            D'Urso,M., Kelso,J., Hide,W. and Ko,M.S.
  TITLE     Transcriptome analysis of mouse stem cells and early embryos
  JOURNAL   PLoS Biol 1 (3), E74 (2003)
   PUBMED   14691545
REFERENCE   8  (bases 1 to 5093)
  AUTHORS   Wolthuis,R.M., Bauer,B., van 't Veer,L.J., de Vries-Smits,A.M.,
            Cool,R.H., Spaargaren,M., Wittinghofer,A., Burgering,B.M. and
            Bos,J.L.
  TITLE     RalGDS-like factor (Rlf) is a novel Ras and Rap 1A-associating
            protein
  JOURNAL   Oncogene 13 (2), 353-362 (1996)
   PUBMED   8710374
REFERENCE   9  (bases 1 to 5093)
  AUTHORS   Kikuchi,A., Demo,S.D., Ye,Z.H., Chen,Y.W. and Williams,L.T.
  TITLE     ralGDS family members interact with the effector loop of ras p21
  JOURNAL   Mol Cell Biol 14 (11), 7483-7491 (1994)
   PUBMED   7935463
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from AC123613.16, BY245021.1,
            AC118051.7, CN693385.1, AK169109.1 and AC123732.9.
            
            Summary: This gene encodes a member of the Ras-like (Ral)
            -selective guanine nucleotide exchange factor (RalGEF) family of
            small GTPase activators which function both as downstream effectors
            of activated Ras GTPase and as regulators of certain Ral GTPases in
            the RalGEF - Ral GTPase signaling pathway. The encoded protein,
            like other RalGEFs, has an N-terminal ras exchanger motif domain, a
            catalytic CDC25 homology domain, and a C-terminal ras binding
            domain that stimulates guanine nucleotide exchange when bound to a
            Ral GTPase. RalGEF family members bridge the Ras and Ral signaling
            pathways and are thought to play a role in oncogenic
            transformation. Alternative splicing results in multiple transcript
            variants. [provided by RefSeq, Sep 2016].
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR9219379.16542.1,
                                           SRR9219382.141413.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN00849374,
                                           SAMN00849375 [ECO:0006172]
            ##Evidence-Data-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-219               AC123613.16        129015-129233       c
            220-399             BY245021.1         220-399
            400-566             AC123613.16        37788-37954         c
            567-677             AC118051.7         39302-39412
            678-836             AC118051.7         76615-76773
            837-1274            CN693385.1         1-438
            1275-3314           AK169109.1         889-2928
            3315-3375           AC118051.7         144690-144750
            3376-5093           AC123732.9         156903-158620       c
FEATURES             Location/Qualifiers
     source          1..5093
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="1"
                     /map="1 64.85 cM"
     gene            1..5093
                     /gene="Rgl1"
                     /gene_synonym="mKIAA0959; Rgl"
                     /note="ral guanine nucleotide dissociation
                     stimulator,-like 1"
                     /db_xref="GeneID:19731"
                     /db_xref="MGI:MGI:107484"
     exon            1..399
                     /gene="Rgl1"
                     /gene_synonym="mKIAA0959; Rgl"
                     /inference="alignment:Splign:2.1.0"
     exon            400..566
                     /gene="Rgl1"
                     /gene_synonym="mKIAA0959; Rgl"
                     /inference="alignment:Splign:2.1.0"
     CDS             435..2846
                     /gene="Rgl1"
                     /gene_synonym="mKIAA0959; Rgl"
                     /note="isoform 1 is encoded by transcript variant 1;
                     ralGDS-like 1"
                     /codon_start=1
                     /product="ral guanine nucleotide dissociation
                     stimulator-like 1 isoform 1"
                     /protein_id="NP_001333046.1"
                     /db_xref="CCDS:CCDS87891.1"
                     /db_xref="GeneID:19731"
                     /db_xref="MGI:MGI:107484"
                     /translation="MEGTSVGEPTQVVSKVKLSTKGENTGHWLVDDHARIWEVLKTEE
                     SSIQDWGEEVEEGAVYHVTLKRVQIQQAANKGARWLGVEGDQLPPGHTVSQYETCKIR
                     TIKAGTLEKLVENLLTAFGDNDFTYISIFLSTYRGFASTKEVLELLLDRYGNLTGPNC
                     EDDGSQSSPESKAVIRNAIASILRAWLDQCAEDFREPPHFPCLQKLLEYLKQMMPGSD
                     PERRAQNLLEQFQKQDVDSDNGLLNTSSFSLEEEEELESGGSAEFTNFSEDLVAEQLT
                     YMDAQLFKKVVPHHCLGCIWSQRDKKENKHLAPTIRATISQFNTLTKCVVSTVLGSKE
                     LKTQQRARVIEKWINIAHECRILKNFSSLRAIVSALQSNSIYRLKKAWAAVPKDRMLM
                     FEELSDIFSDHNNHLTSRELLMKEGTSKFANLDSSVKENQKRTQRRLQLQKDMGVMQG
                     TVPYLGTFLTDLTMLDTALQDYIEGGLINFEKRRREFEVIAQIKLLQSACNSYCMGPD
                     QKFIQWFQRQQLLSEEESYALSCEIEAAADANTTSPKPRKSMVKRLSLLFLGSDIIPG
                     STPTKEQPKSAASGSSGESMDSVSVSSCESNHSEAEEGPVTPMDTPDEPQKKLSESSS
                     SCSSIHSMDTNSSGMSSLINPLSSPPTCNNNPKIHKRSVSVTSITSTVLPPVYNQQNE
                     DTCIIRISVEDNNGNMYKSIMLTSQDKTPAVIQRAMSKHNLESDPAEEYELVQVISED
                     KELVIPDSANVFYAMNSQVNFDFILRKKNSVEEQVKLRSRTSLTLPRTAKRGCWSNRH
                     SKITL"
     exon            567..677
                     /gene="Rgl1"
                     /gene_synonym="mKIAA0959; Rgl"
                     /inference="alignment:Splign:2.1.0"
     exon            678..886
                     /gene="Rgl1"
                     /gene_synonym="mKIAA0959; Rgl"
                     /inference="alignment:Splign:2.1.0"
     exon            887..964
                     /gene="Rgl1"
                     /gene_synonym="mKIAA0959; Rgl"
                     /inference="alignment:Splign:2.1.0"
     exon            965..1149
                     /gene="Rgl1"
                     /gene_synonym="mKIAA0959; Rgl"
                     /inference="alignment:Splign:2.1.0"
     exon            1150..1274
                     /gene="Rgl1"
                     /gene_synonym="mKIAA0959; Rgl"
                     /inference="alignment:Splign:2.1.0"
     exon            1275..1490
                     /gene="Rgl1"
                     /gene_synonym="mKIAA0959; Rgl"
                     /inference="alignment:Splign:2.1.0"
     exon            1491..1594
                     /gene="Rgl1"
                     /gene_synonym="mKIAA0959; Rgl"
                     /inference="alignment:Splign:2.1.0"
     exon            1595..1679
                     /gene="Rgl1"
                     /gene_synonym="mKIAA0959; Rgl"
                     /inference="alignment:Splign:2.1.0"
     exon            1680..1769
                     /gene="Rgl1"
                     /gene_synonym="mKIAA0959; Rgl"
                     /inference="alignment:Splign:2.1.0"
     exon            1770..1856
                     /gene="Rgl1"
                     /gene_synonym="mKIAA0959; Rgl"
                     /inference="alignment:Splign:2.1.0"
     exon            1857..1889
                     /gene="Rgl1"
                     /gene_synonym="mKIAA0959; Rgl"
                     /inference="alignment:Splign:2.1.0"
     exon            1890..2011
                     /gene="Rgl1"
                     /gene_synonym="mKIAA0959; Rgl"
                     /inference="alignment:Splign:2.1.0"
     exon            2012..2101
                     /gene="Rgl1"
                     /gene_synonym="mKIAA0959; Rgl"
                     /inference="alignment:Splign:2.1.0"
     exon            2102..2288
                     /gene="Rgl1"
                     /gene_synonym="mKIAA0959; Rgl"
                     /inference="alignment:Splign:2.1.0"
     exon            2289..2543
                     /gene="Rgl1"
                     /gene_synonym="mKIAA0959; Rgl"
                     /inference="alignment:Splign:2.1.0"
     exon            2544..2658
                     /gene="Rgl1"
                     /gene_synonym="mKIAA0959; Rgl"
                     /inference="alignment:Splign:2.1.0"
     exon            2659..5093
                     /gene="Rgl1"
                     /gene_synonym="mKIAA0959; Rgl"
                     /inference="alignment:Splign:2.1.0"
     regulatory      3297..3302
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Rgl1"
                     /gene_synonym="mKIAA0959; Rgl"
                     /note="hexamer: AATAGA"
     polyA_site      3316
                     /gene="Rgl1"
                     /gene_synonym="mKIAA0959; Rgl"
                     /note="major polyA site"
     regulatory      4299..4304
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Rgl1"
                     /gene_synonym="mKIAA0959; Rgl"
                     /note="hexamer: AATAAA"
     polyA_site      4325
                     /gene="Rgl1"
                     /gene_synonym="mKIAA0959; Rgl"
                     /note="major polyA site"
     regulatory      5048..5053
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Rgl1"
                     /gene_synonym="mKIAA0959; Rgl"
                     /note="hexamer: AATAAA"
     polyA_site      5093
                     /gene="Rgl1"
                     /gene_synonym="mKIAA0959; Rgl"
                     /note="major polyA site"
ORIGIN      
        1 ggtcttgggc tggaggctat gggcacctcg ggagcgtggc ctggagtgct gctgccgccg
       61 ccgctgtcgg tgccagccgc tggttgttgg ggtccggtgt gaagtgtggg tgaccggact
      121 cgcgcgtggg gtgcgatgga ctggctgcag aacctagtcc cctgcagtct gcaggagtat
      181 gaggcaaagt gatgcccagc tcggaactag tgatcggagc cctccattcg gaccgtgcgc
      241 cgccgggggc tgccttcccg agctgagagc cccttccccg gcttggactc ttggcacgct
      301 gtcggtggga ggtccccaag gacggaatcg aaaaggtcac ttcttacctg tcagtgctgt
      361 gtgacagcat cgcgaccgga cctgcagaat ctgaactagc agattcgtaa tgcctcctgc
      421 ttacctcttt caagatggag gggacatctg tgggagagcc tactcaagtg gtgtctaaag
      481 tcaaactttc cacaaaagga gaaaacacag gacactggct ggtggatgat catgctcgaa
      541 tatgggaagt tttgaagaca gaggagagct cgattcagga ctggggtgaa gaggtagagg
      601 aaggagctgt ttaccatgtc accctcaaaa gagtccagat tcaacaggcg gccaataaag
      661 gagcgagatg gctaggggtt gaaggggacc agctgcctcc aggacacaca gtcagtcagt
      721 acgagacctg caagatcagg accatcaaag ctggtacgct ggagaagctt gtggagaacc
      781 tgctgacggc ttttggggac aatgacttta cctacatcag catctttttg tcgacataca
      841 gaggctttgc ctcgactaag gaagtgctgg agctgctgct ggacaggtat ggaaacctga
      901 caggcccaaa ctgtgaagac gatggaagcc aaagttcacc cgagtccaag gccgtgatcc
      961 ggaatgccat tgcttccatc ctgagggcct ggcttgacca gtgtgcggaa gacttccggg
     1021 agccccctca cttcccttgc cttcagaagc tgctggagta cctcaaacag atgatgcctg
     1081 gctctgaccc agagaggaga gcacagaacc ttcttgaaca gtttcaaaag caggacgtgg
     1141 attccgacaa tggacttctc aacaccagct ccttcagcct ggaagaggaa gaggaactgg
     1201 agagcggagg gtcagcagaa ttcacgaact tctcagaaga tctcgtggca gaacagctga
     1261 cctacatgga cgcacaacta ttcaagaagg tagtgcctca ccattgcctg ggctgtattt
     1321 ggtctcagcg ggataaaaag gaaaacaagc atttggctcc tacgatccgt gccaccatct
     1381 ctcagtttaa tacgctcacc aagtgtgttg tcagcaccgt cctggggagc aaggaactca
     1441 aaactcagca gcgagccaga gtcatcgaga agtggatcaa cattgctcac gaatgtagaa
     1501 tcctgaagaa tttttcctcc ttgagggcca tcgtttccgc actgcagtct aattccatct
     1561 atcggttgaa aaaggcttgg gctgctgtcc cgaaggacag aatgctgatg tttgaagaac
     1621 tttcagatat cttctctgat cacaataacc atctaaccag tcgggagcta ctaatgaagg
     1681 aaggaacttc aaaatttgca aacctggaca gcagcgtgaa agaaaaccag aagcggaccc
     1741 agaggcgcct gcaactgcag aaggatatgg gtgtgatgca gggtaccgtg ccttacctgg
     1801 gcaccttcct gactgacctg accatgctgg acactgccct gcaggactac attgagggtg
     1861 gactgatcaa cttcgagaaa agaagaaggg aatttgaagt cattgcccag ataaagctcc
     1921 tacagtctgc ttgcaacagc tactgcatgg gcccagacca gaagtttatc cagtggttcc
     1981 agaggcagca gcttctatca gaggaggaaa gctacgccct ctcgtgtgag attgaagccg
     2041 ctgccgacgc caacaccact tcccctaagc ctcggaaaag catggtgaag aggctgagcc
     2101 tgctatttct ggggtctgac atcatccccg ggagcactcc caccaaagag cagcccaagt
     2161 ccgcagccag tgggagctct ggggagagta tggactcagt cagtgtgtcg tcctgtgaat
     2221 caaaccactc cgaggctgag gagggccccg tcacacccat ggacacacca gatgagcccc
     2281 aaaagaagct ctctgaatcc tcctcttcct gttcctccat ccattccatg gacacgaatt
     2341 cctcagggat gtcgtcccta atcaaccccc tgtcctcccc tccaacgtgc aacaacaatc
     2401 ctaaaatcca caagcgctcc gtctccgtga catccattac ctccacagta ctgcctcctg
     2461 tttacaatca gcagaacgaa gacacctgca tcatccgcat cagtgtagaa gacaacaatg
     2521 gcaacatgta caagagcatc atgctgacaa gccaggataa gacccccgct gtgatccaga
     2581 gagcgatgtc gaagcacaac ctggagtcgg accccgccga ggagtatgag ctggtgcagg
     2641 tcatctcgga ggacaaagaa ctagtgatcc cggactctgc aaacgtcttt tacgccatga
     2701 atagccaagt gaactttgat ttcattttac gcaaaaagaa ctcggtggag gagcaggtga
     2761 agttgcgcag tcggaccagc ctgactttgc ccaggacagc taagcggggc tgctggagta
     2821 acaggcacag caagatcacc ctctgaaagg gacagtacac tcctactgcc caaggcagag
     2881 tgaggctgag caaaagccat ggcgacgcca accaccaccc agtgttgagc atcattggtg
     2941 aaagcgacag atatttatag aattcagctg tgcagagagc actgtgcagg ggagagtgga
     3001 agtgaatttg acattaaaag gataaaaggt tcactgatgc tcttagatct gagagtgaat
     3061 acaaaatagt ccatatttta aaatatatat acacacgcat atcgtgtgtg tatgcgtgtg
     3121 tttgtgtgtg tgtgtgtgtg tgtgtgtgtg tgtgtgtgta tgtagatata ccagagggac
     3181 tatacaggat attctggact atggaaaaac caatttgcac aatggcctgg gaagttgagg
     3241 tcacttttta cagggaaaca gaagggacca agaacctggt ctcatacttc caagtaaata
     3301 gaattagaac taccaatgcg gagtgttctt catgccagta ttacaagccc aggctcttat
     3361 ttttgtaaag ggagagaatt cctttctcag tcatgtgcca ccagatgacc aaacagcaga
     3421 gattgacatg gccataggct gcatgaaagg ccaccatgga aaggttcgga tgggtcagtg
     3481 gtctctgccc cctgctggag tctgctggag catctgaggc ctgtgtgcct tgctggtccc
     3541 cgtcacaatg cccctggggt caacacaagc ttgtttcaat tcctggaaac cctgttgtgt
     3601 ttctgcattc tctcctgagg aacgcaccac aatcattacc acacaggtag cctcggtctt
     3661 ccataacttt tcagccagag aagaaagcgc agaagcacag caactcctct ggactctcct
     3721 ctgtcttgga ccactccacc accctctgat tgcctttgca tgtagcagtg tacatccggt
     3781 cgtttgccat ctttagctgt gggcctctgt cttatgagca gttcttcctc aggtgtagac
     3841 atttctgctg cagtcaactc catgcaatca tttcaagcct gtgaaagatt tctgagcagc
     3901 aacccccccc cccccccccc gtcaacccct cagaaactgt ctcccactga ctaaccgcgg
     3961 ctcctgtttc cttctttact ttagtagcat tcctgtgttc aggtcacagg gagagaaagg
     4021 agactgcgac tgccgtctct gtcctttctc acagcagtgc acccttatag aagggaagag
     4081 tcgcgctctt ctttctcacc tctcacttac tctcctggtg gcgctggtaa gtgatgggtt
     4141 ttgtctgtaa taacagtttc attctgtgct tccgatctgc gctatgctgg gatctgaatg
     4201 gaaaagccat acatgaagga gctgacatgt ataagaagca ctttcaaatt attgttcctt
     4261 tttaattttt ttctccaaat accagttttt attccaaaaa taaagagaat gaacccagaa
     4321 tacgatatcc agattgtaac agggactttt tttttctaac cctatacttt agctctcaaa
     4381 ggttatgtag ggtttgtgtt atgtaaatag ccatacgaac tcaacaagaa acaccaggaa
     4441 aagctcagag atttgtggca gtggaccaaa gagagagcca ggaagtcatc agattccctt
     4501 gtcttgtaca ttctgacacc agatgtaccc tgctgtttct aggagactgg actggaagac
     4561 cagttagctt tcgactaatc atccgaaggc actctcttct tttgtttgtg agcctttttt
     4621 ggttaatgtt tctgtgtgtg gtagggagat ggtaaggatt acagccatca ggaagactga
     4681 ggtaacccta gcctcagcct ggctttctca gtgtcaaggt caaaaagtca gtgcagagct
     4741 attggcctgg tttagggtgt ggcacacaag acatacatgt tatgaccatg tgctcaccct
     4801 gtgtaattat actgtatatg tagagcctag atttatatac tgcaatgtaa aatatatata
     4861 tatatatatt taccttttta aaaaaaagac aatggaaatc ccaagtgggt aaaacatggc
     4921 ctcatttatt taatgccact tcagttgttt taattttgct tccaggtaaa cagctggact
     4981 ttgtttccag ctgctcgcac gcttgtcttt ccgcatctac agcatctgtt taccttttgg
     5041 ttaaactaat aaactggttt gggacttggt tggcatgtgc tgccagaccc aaa
//
