LOCUS       NM_001145660            2024 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus regulatory factor X 8 (Rfx8), mRNA.
ACCESSION   NM_001145660 XM_001478116 XM_890488
VERSION     NM_001145660.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2024)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 2024)
  AUTHORS   Koscielny,G., Yaikhom,G., Iyer,V., Meehan,T.F., Morgan,H.,
            Atienza-Herrero,J., Blake,A., Chen,C.K., Easty,R., Di Fenza,A.,
            Fiegel,T., Grifiths,M., Horne,A., Karp,N.A., Kurbatova,N.,
            Mason,J.C., Matthews,P., Oakley,D.J., Qazi,A., Regnart,J.,
            Retha,A., Santos,L.A., Sneddon,D.J., Warren,J., Westerberg,H.,
            Wilson,R.J., Melvin,D.G., Smedley,D., Brown,S.D., Flicek,P.,
            Skarnes,W.C., Mallon,A.M. and Parkinson,H.
  TITLE     The International Mouse Phenotyping Consortium Web Portal, a
            unified point of access for knockout mice and related phenotyping
            data
  JOURNAL   Nucleic Acids Res 42 (Database issue), D802-D809 (2014)
   PUBMED   24194600
REFERENCE   3  (bases 1 to 2024)
  AUTHORS   Mu,X., Zhao,S., Pershad,R., Hsieh,T.F., Scarpa,A., Wang,S.W.,
            White,R.A., Beremand,P.D., Thomas,T.L., Gan,L. and Klein,W.H.
  TITLE     Gene expression in the developing mouse retina by EST sequencing
            and microarray analysis
  JOURNAL   Nucleic Acids Res 29 (24), 4983-4993 (2001)
   PUBMED   11812828
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK133372.1, AC122922.4 and BG808411.1.
            
            On or before Mar 11, 2009 this sequence version replaced
            XM_001478116.1, XM_890488.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK133372.1, SRR17784647.657404.1
                                           [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN00849374,
                                           SAMN00849378 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-557               AK133372.1         12-568
            558-898             AK133372.1         570-910
            899-899             AC122922.4         105531-105531
            900-1995            AK133372.1         912-2007
            1996-2024           BG808411.1         1-29                c
FEATURES             Location/Qualifiers
     source          1..2024
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="1"
                     /map="1 18.41 cM"
     gene            1..2024
                     /gene="Rfx8"
                     /gene_synonym="4933400N17Rik"
                     /note="regulatory factor X 8"
                     /db_xref="GeneID:619289"
                     /db_xref="MGI:MGI:3588206"
     exon            1..112
                     /gene="Rfx8"
                     /gene_synonym="4933400N17Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             48..1838
                     /gene="Rfx8"
                     /gene_synonym="4933400N17Rik"
                     /codon_start=1
                     /product="DNA-binding protein RFX8"
                     /protein_id="NP_001139132.1"
                     /db_xref="CCDS:CCDS48245.1"
                     /db_xref="GeneID:619289"
                     /db_xref="MGI:MGI:3588206"
                     /translation="MAEAVPASPASGLGLHRGIIQWLVDNFCICEGFSVPRCLMYEIY
                     VETCGQSAQNQVNPATFGKLVRLVFPDLGTRRLGTRGSARYHYDGIYIKKSSFFYAHY
                     CYLLGKKSCHSGNLIAFGKFPDYSNVLQQEETCENHSPIKKDPMGSPVSPFRRCPVWE
                     QELANKYSCKLVVFLADEYCNYCRDILQNVRNQELEKVEDLITSFWKSRQQDTVMLMS
                     LPDVRQLLGCYDMQLYKGLEDMLLPDFLEDVSIQYLKSVRLFSKRFKLWLLGALEGFP
                     AILQISKLKEVTGFVKRLRRKTYLSNMAKTMKMVLKNSRRIGLLKSDLRAIIREGTLD
                     ISKKVLEGDSDHEEEPESHTEMKCLGCLISLLETSTDLAELLNCVSSNLQVLVFQPSK
                     NKEDFIKLAASFQLKWNFLLTAVSKAMTLSHRDSFGAWHLFHLLLLEYVIHILESCIE
                     EEEEEDLGSLQDLLSDDQFLTQPDQALFHPLDSLPTSECASRNVESPQVTLKHTSQSC
                     GPMGMGSVVLQVLGFLVDTATGNKLVQVLLEDKTTESAVKLSLPVGQEALITLSNGQR
                     FVIHISDVPQSSENTYCRKSNANVQGGLLE"
     exon            113..236
                     /gene="Rfx8"
                     /gene_synonym="4933400N17Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            237..298
                     /gene="Rfx8"
                     /gene_synonym="4933400N17Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            299..385
                     /gene="Rfx8"
                     /gene_synonym="4933400N17Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            386..449
                     /gene="Rfx8"
                     /gene_synonym="4933400N17Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            450..560
                     /gene="Rfx8"
                     /gene_synonym="4933400N17Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            561..638
                     /gene="Rfx8"
                     /gene_synonym="4933400N17Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            639..752
                     /gene="Rfx8"
                     /gene_synonym="4933400N17Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            753..903
                     /gene="Rfx8"
                     /gene_synonym="4933400N17Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            904..962
                     /gene="Rfx8"
                     /gene_synonym="4933400N17Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            963..1119
                     /gene="Rfx8"
                     /gene_synonym="4933400N17Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1120..1214
                     /gene="Rfx8"
                     /gene_synonym="4933400N17Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1215..1329
                     /gene="Rfx8"
                     /gene_synonym="4933400N17Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1330..1643
                     /gene="Rfx8"
                     /gene_synonym="4933400N17Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1644..2000
                     /gene="Rfx8"
                     /gene_synonym="4933400N17Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1979..1984
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Rfx8"
                     /gene_synonym="4933400N17Rik"
                     /note="hexamer: TATAAA"
     polyA_site      2000
                     /gene="Rfx8"
                     /gene_synonym="4933400N17Rik"
                     /note="major polyA site"
ORIGIN      
        1 cacggcggag aggaccggtg ccccgctcgc tgcccgctgg gcgaggcatg gcggaggcgg
       61 tgccggcctc tcctgcgagt ggcctgggcc tgcaccgggg tatcattcaa tggctggttg
      121 acaatttctg catctgtgaa gggttcagcg tgccccgatg tctcatgtat gagatttatg
      181 tcgagacctg tgggcagagt gctcagaacc aagtcaaccc agcgacattt gggaagcttg
      241 tgcgcttggt tttccctgac ctgggcaccc ggaggctggg cacacgagga agtgccaggt
      301 atcattatga tgggatctac atcaagaaga gctccttctt ctacgctcat tactgctacc
      361 tgctgggtaa aaagagctgt cacagtggca atcttattgc cttcggaaaa tttcctgact
      421 atagcaacgt tctccagcag gaagaaacat gtgaaaatca ttcaccaata aagaaggacc
      481 cgatgggctc acctgtgtct ccattcagaa gatgtccggt ctgggaacaa gagctggcaa
      541 acaagtactc ctgtaagctg gtggtctttc ttgctgatga atactgcaac tactgtcgag
      601 acattttaca gaatgtgagg aaccaagaac tggagaaggt ggaggattta atcacatcct
      661 tctggaaatc tcggcagcaa gacacagtca tgctcatgtc tctgcccgac gtgcgccagc
      721 tcttaggatg ctatgacatg cagctgtata agggcctgga agacatgctg ctccccgact
      781 tcctggagga cgttagtatc cagtacctga aatctgtccg gctgtttagt aagagattta
      841 aactgtggct tctcggtgct ctggaagggt ttcctgccat cttacagatc tctaagctca
      901 aagaagtcac tggattcgtc aaaagactca ggagaaagac gtacctttcc aacatggcga
      961 agacgatgaa aatggtcctg aagaacagca ggagaatcgg cctcttgaag tcagaccttc
     1021 gtgccatcat cagagaaggc actctggata tttcgaagaa ggtcctggaa ggtgactccg
     1081 accatgaaga ggagccagag agccacacag agatgaaatg cttaggctgt ttaatttctt
     1141 tgctggaaac ttcaacagat cttgctgaac tcctgaactg tgtgtcttca aacctccaag
     1201 tgcttgtctt ccagccgagc aaaaacaaag aggattttat caagctcgct gccagctttc
     1261 aactgaaatg gaattttctt ctcaccgccg tgagcaaagc catgaccctg agccacagag
     1321 acagtttcgg tgcctggcat ctgtttcatc tgctgctctt ggaatatgtg attcacatcc
     1381 tggagtcatg catagaagag gaggaagagg aggacctggg gagcctccag gacctgctgt
     1441 cagatgacca gttcctcacc cagccagacc aggccctttt ccaccctctg gattctttgc
     1501 caacatcgga atgtgcaagc cggaatgtgg agtcacctca ggtgacgctg aaacacacga
     1561 gccagagctg cggtcccatg ggcatgggca gcgtggttct ccaggtgctg ggcttcctgg
     1621 tggacaccgc cacaggcaat aagcttgtcc aggtattgct ggaggacaaa accactgaga
     1681 gcgctgtgaa gctcagcctt cccgtgggac aagaggccct cataacccta agcaatggac
     1741 agaggtttgt gatccacata tcagatgtgc cccaaagctc agaaaacacg tattgcagga
     1801 aaagcaacgc gaacgtgcaa ggtggtttgc tggagtaggg tgtgaggaag caggcttgag
     1861 ttctccaaac atgtgtggaa ccctaaagtt tttgtattga tctcggagac tttaatgtat
     1921 ataatagatg aggcgtttta tgtttgtatg tattttgagg aattgtattt gatcaaacta
     1981 taaactaatt ttgagaataa aaaaaaaaaa aaaaaaaaaa aaaa
//
