LOCUS       NM_029658               3533 bp    mRNA    linear   ROD 01-JUN-2024
DEFINITION  Mus musculus refilin B (Rflnb), mRNA.
ACCESSION   NM_029658 XM_893392 XM_983541
VERSION     NM_029658.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3533)
  AUTHORS   Kaji,D.A., Montero,A.M., Patel,R. and Huang,A.H.
  TITLE     Transcriptional profiling of mESC-derived tendon and fibrocartilage
            cell fate switch
  JOURNAL   Nat Commun 12 (1), 4208 (2021)
   PUBMED   34244516
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3533)
  AUTHORS   Mizuhashi,K., Kanamoto,T., Moriishi,T., Muranishi,Y., Miyazaki,T.,
            Terada,K., Omori,Y., Ito,M., Komori,T. and Furukawa,T.
  TITLE     Filamin-interacting proteins, Cfm1 and Cfm2, are essential for the
            formation of cartilaginous skeletal elements
  JOURNAL   Hum Mol Genet 23 (11), 2953-2967 (2014)
   PUBMED   24436304
  REMARK    GeneRIF: Filamin a, b-interacting proteins, Cfm1 and Cfm2, are
            essential for the formation of cartilaginous skeleton.
REFERENCE   3  (bases 1 to 3533)
  AUTHORS   Shalom-Barak,T., Zhang,X., Chu,T., Timothy Schaiff,W., Reddy,J.K.,
            Xu,J., Sadovsky,Y. and Barak,Y.
  TITLE     Placental PPARgamma regulates spatiotemporally diverse genes and a
            unique metabolic network
  JOURNAL   Dev Biol 372 (1), 143-155 (2012)
   PUBMED   22967998
REFERENCE   4  (bases 1 to 3533)
  AUTHORS   Gay,O., Gilquin,B., Nakamura,F., Jenkins,Z.A., McCartney,R.,
            Krakow,D., Deshiere,A., Assard,N., Hartwig,J.H., Robertson,S.P. and
            Baudier,J.
  TITLE     RefilinB (FAM101B) targets filamin A to organize perinuclear actin
            networks and regulates nuclear shape
  JOURNAL   Proc Natl Acad Sci U S A 108 (28), 11464-11469 (2011)
   PUBMED   21709252
REFERENCE   5  (bases 1 to 3533)
  AUTHORS   Warnecke,M., Oster,H., Revelli,J.P., Alvarez-Bolado,G. and
            Eichele,G.
  TITLE     Abnormal development of the locus coeruleus in
            Ear2(Nr2f6)-deficient mice impairs the functionality of the
            forebrain clock and affects nociception
  JOURNAL   Genes Dev 19 (5), 614-625 (2005)
   PUBMED   15741322
REFERENCE   6  (bases 1 to 3533)
  AUTHORS   Hirano,M., Murata,T., Furushima,K., Kiyonari,H., Nakamura,M.,
            Suda,Y. and Aizawa,S.
  TITLE     cfm is a novel gene uniquely expressed in developing forebrain and
            midbrain, but its null mutant exhibits no obvious phenotype
  JOURNAL   Gene Expr Patterns 5 (3), 439-444 (2005)
   PUBMED   15661651
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK005164.1, AA016881.1, AL645569.21 and W81812.1.
            
            On or before Nov 18, 2009 this sequence version replaced
            XM_983541.2, XM_893392.3.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK005164.1, SRR10662772.1987743.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849375, SAMN00849376
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-175               AK005164.1         3-177
            176-609             AA016881.1         65-498
            610-1454            AK005164.1         612-1456
            1455-3426           AL645569.21        109711-111682       c
            3427-3533           W81812.1           318-424
FEATURES             Location/Qualifiers
     source          1..3533
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="11"
                     /map="11 45.92 cM"
     gene            1..3533
                     /gene="Rflnb"
                     /gene_synonym="1500005K14Rik; cfm; Fam101b; RefilinB"
                     /note="refilin B"
                     /db_xref="GeneID:76566"
                     /db_xref="MGI:MGI:1923816"
     exon            1..355
                     /gene="Rflnb"
                     /gene_synonym="1500005K14Rik; cfm; Fam101b; RefilinB"
                     /inference="alignment:Splign:2.1.0"
     CDS             146..796
                     /gene="Rflnb"
                     /gene_synonym="1500005K14Rik; cfm; Fam101b; RefilinB"
                     /note="protein FAM101B; regulator of filamin protein B;
                     filamin-interacting protein FAM101B; family with sequence
                     similarity 101, member B"
                     /codon_start=1
                     /product="refilin-B"
                     /protein_id="NP_083934.1"
                     /db_xref="CCDS:CCDS48851.1"
                     /db_xref="GeneID:76566"
                     /db_xref="MGI:MGI:1923816"
                     /translation="MVGRLSLQDVPELVDTKKKGDGVLDSPDSGLPPSPSPSHWGLAA
                     TAGGGGERAPVAGTLEPDAAVTPIVPNPASLTHSLAAICSPRLCPLSFGEGVEFDPLP
                     PKEIKYTSSVKYDSERHFIDDVQMPLGLVVASCSQTVTCIPNCTWRNYKAEVRFEPRP
                     KPARFLSTTIVYPKYPKTVYTTTLDYNCHKKLRRFLSSVELEATEFLGSDGLADEC"
     exon            356..465
                     /gene="Rflnb"
                     /gene_synonym="1500005K14Rik; cfm; Fam101b; RefilinB"
                     /inference="alignment:Splign:2.1.0"
     exon            466..3512
                     /gene="Rflnb"
                     /gene_synonym="1500005K14Rik; cfm; Fam101b; RefilinB"
                     /inference="alignment:Splign:2.1.0"
     regulatory      3491..3496
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Rflnb"
                     /gene_synonym="1500005K14Rik; cfm; Fam101b; RefilinB"
                     /note="hexamer: AATAAA"
     polyA_site      3512
                     /gene="Rflnb"
                     /gene_synonym="1500005K14Rik; cfm; Fam101b; RefilinB"
                     /note="major polyA site"
ORIGIN      
        1 gcggccgctg gcgacacccg gacaacgcgc cggcggcggg gcaaggaggg cagcccggag
       61 ggcagcggcc ccggcccgcg tgtgcggccc tctcttgcac tccaacaccg cggcggctgt
      121 gcccggtccc gccacacgtg cagctatggt gggccggctg agcctgcagg atgtccctga
      181 actcgtggac acgaagaaaa aaggcgacgg cgtcctggac agcccggact cggggctgcc
      241 cccaagccct agccccagcc actgggggct cgcagcgacg gcgggcggcg gtggggagcg
      301 cgctccggtc gcagggacgc tggagcccga tgcggcggtg acccctatag tcccgaaccc
      361 agcatctctg acccactcgc tagctgccat ctgctcaccg agactctgtc ccctgtcctt
      421 cggcgaagga gttgagtttg accccttgcc accaaaggaa ataaagtata cctcctcagt
      481 caagtatgac tctgagcggc acttcatcga tgatgtacag atgcccctgg gtctggtggt
      541 ggcttcctgc agccagacag tcacctgtat ccccaactgc acttggcgaa actataaggc
      601 ggaagtgcgc ttcgagccac gccccaagcc cgcgcgtttc ctcagcacca ccatcgtcta
      661 ccccaagtac cccaaaaccg tctacaccac cactctggat tacaactgcc acaagaagct
      721 gaggaggttt ctgtccagtg tggagctcga ggccacggag ttcctgggca gcgatgggct
      781 agccgatgaa tgttgactca gctagcttga ggttggacca gctgttcata cactgccctg
      841 gtccccagac caccctggac aagctgggta gcattgctct tgcacatcac cccagcccca
      901 gagggatcta acctggagat acctctaagc ctagccgggg gaagatgtat ttaaaaaaaa
      961 aaaaatcact gcatcttata ataatagaga aactcggctt ccttaaaaat ttttccagat
     1021 agttaaaaaa aaaaaaagtg tgtgtgtgtg tgtgtgtgtg tgtgtgtgtg tgtgtattct
     1081 ggttggttga tgcagtttcc ccaaagtctc aagttgatga gaaaatagag gcagaacaaa
     1141 aggacaatga taggacagtg atatctgggc aggtggaggt gagcttgtcc tccattttct
     1201 gatgaacaaa gtaggaaagt ctctggaata cagaaggtgc gttaagaaat ttcagccatg
     1261 catatgttta ttgctggggg cggggagggg gagaagccag agttaacttg ggtagactgt
     1321 gatgcccata tgtgctcaat ctgttctggg ccagcttttt ttgtttgttt gtttctgctt
     1381 ctatttgttt ttcctgttaa cccaaactct tagatttatc aaaaatcttt ttcatgatat
     1441 taggggagaa aaacaaaaac aaaaaaaaac acaaaaggag atgcctttaa aacaaactct
     1501 gtgccttccg ctgttgtcgg ttgggtaaac agctagcctg gtccgaggca ccgcagccct
     1561 gtggttccag agggttggtt tcaggcccag gctctggtgc agcccgagca tgcttggcgt
     1621 ctggttaacg tctccccggg cttgtgtaac tctgctcata ggtatttggg gttttgaaat
     1681 acttttcctt tttttttttt catgcaaaat gcagcagaga gctctttttt agaagaacgg
     1741 cattctgaaa gaatgctttg gaaaaacatg ctttgggggc tgcaaggaaa gggtctccac
     1801 tgtgggccac cgtgcctgag cccagatgcc gacaggagga ggaggcaggt ttaaatgtga
     1861 ctcagatcct tgcgattaaa tgatggactt attctttgga ctctgatagt gtcgaaactg
     1921 ggaggaatgg ggtttaaccc aaaaaagcaa gactgttgct taccacccag attaagctaa
     1981 gatgaattca ggagtaggga gtgacacgta gactccacaa ccttgccact gtggtgatgg
     2041 gagacatttc tttcatacca ctgaatattc gggagtgact attgtggagt caggtatgca
     2101 caaaggtgtt tcccagccta cttccagaat ccagctgagc cagctacagc agcaggggca
     2161 gtgctgggca ggagggtgct gtgcaccaac ctgccccctg ctcccctgcc cctacccctg
     2221 gcctagccct tgcttcttag aatcccctgc caggccccac tgctggagtg aaggaagtgg
     2281 caggctgagt tttattccag gatcagaaag aacaagtcgt atgtgtttcc tttgaataca
     2341 tccaaatcat gtcaagtggg ttactggagg ctctgccttc ccttgtatct ctgggtctct
     2401 gtgatagctt ccatctgctc agaaagcaaa attgagagca cacgggcttc cctggatcca
     2461 cagcagagac tggttatcat ggaaagcagg tgcaaaaata atcactttca ttttaaagac
     2521 tggcgctgtc tagagccaca tcacctagtc cgtgtcccct gcagatgaca gagtctgttg
     2581 tactttcaac tcatccatct ggacacagag gctgctggca tcatggtccc agttggccag
     2641 ggtacagcac atttggggga caccctggga tcctccaagc tcctcagtaa aacttggctt
     2701 taggaaaaca tttattggca aaagtggatt tttctatctg acttcatcgt gtcactgaag
     2761 catcaaatat aagttctttt ctgcaaatac aatttctaaa ttaggaaaat caccaaagct
     2821 ttgctctgct cctttggaga cacttgcttg ggctcagaac gatgtcatgg ccagcatgtc
     2881 aggagaatat gttgtctgta tgcagcagag ctgtaaaggt gtccttaaga aaaacaaatt
     2941 tttcttttct tgtttttgtc ttagagggat catgttaagt tcaggcagag cattctaggt
     3001 gtggatggag gtggaagcac atcagtaagt cgaagcaagt gactgtggat gtctgatgta
     3061 gatggaaagg caggttttga tgccgttagg ttatttacta gaatcttcac cgattctcca
     3121 aatctgctac gaaagccaca ggcctggaag ctgggcgtgg catcctggag caccctgatg
     3181 gtggtgacgc cgcccagaga agattcctga tggttggcga agtggagaag gaggtttgta
     3241 aaactcaccc acctgacatt cctgagtgtg cgggtgagag acggcttttc ctgccgtctg
     3301 tctcgtaagt tctggctgtt ggaggtgatg caggtgtcta gaggcaggtg gttttcctct
     3361 cagatgccta aaaaggactt gatgtaaaca agcatcttgt catttgacac acgccaaaaa
     3421 aaaaaagttt taaaattatc ttttgacttc tgtcccactt catttttgct ttgtgacttc
     3481 tctgtttaac aataaatgat ctcaaacata aaaaaaaaaa aaaaaaaaaa aaa
//
