LOCUS       NM_028443               1677 bp    mRNA    linear   ROD 01-JUN-2024
DEFINITION  Mus musculus refilin A (Rflna), mRNA.
ACCESSION   NM_028443 XM_132387
VERSION     NM_028443.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1677)
  AUTHORS   Liu,C.F., Angelozzi,M., Haseeb,A. and Lefebvre,V.
  TITLE     SOX9 is dispensable for the initiation of epigenetic remodeling and
            the activation of marker genes at the onset of chondrogenesis
  JOURNAL   Development 145 (14) (2018)
   PUBMED   30021842
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1677)
  AUTHORS   Chal,J., Al Tanoury,Z., Oginuma,M., Moncuquet,P., Gobert,B.,
            Miyanari,A., Tassy,O., Guevara,G., Hubaud,A., Bera,A., Sumara,O.,
            Garnier,J.M., Kennedy,L., Knockaert,M., Gayraud-Morel,B.,
            Tajbakhsh,S. and Pourquie,O.
  TITLE     Recapitulating early development of mouse musculoskeletal
            precursors of the paraxial mesoderm in vitro
  JOURNAL   Development 145 (6) (2018)
   PUBMED   29555813
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 1677)
  AUTHORS   Mizuhashi,K., Kanamoto,T., Moriishi,T., Muranishi,Y., Miyazaki,T.,
            Terada,K., Omori,Y., Ito,M., Komori,T. and Furukawa,T.
  TITLE     Filamin-interacting proteins, Cfm1 and Cfm2, are essential for the
            formation of cartilaginous skeletal elements
  JOURNAL   Hum Mol Genet 23 (11), 2953-2967 (2014)
   PUBMED   24436304
  REMARK    GeneRIF: Filamin a,b-interacting proteins, Cfm1 and Cfm2, are
            essential for the formation of cartilaginous skeleton.
REFERENCE   4  (bases 1 to 1677)
  AUTHORS   Jerome-Majewska,L.A., Achkar,T., Luo,L., Lupu,F. and Lacy,E.
  TITLE     The trafficking protein Tmed2/p24beta(1) is required for
            morphogenesis of the mouse embryo and placenta
  JOURNAL   Dev Biol 341 (1), 154-166 (2010)
   PUBMED   20178780
REFERENCE   5  (bases 1 to 1677)
  AUTHORS   Hoffman,B.G., Zavaglia,B., Witzsche,J., Ruiz de Algara,T.,
            Beach,M., Hoodless,P.A., Jones,S.J., Marra,M.A. and Helgason,C.D.
  TITLE     Identification of transcripts with enriched expression in the
            developing and adult pancreas
  JOURNAL   Genome Biol 9 (6), R99 (2008)
   PUBMED   18554416
REFERENCE   6  (bases 1 to 1677)
  AUTHORS   Hirano,M., Murata,T., Furushima,K., Kiyonari,H., Nakamura,M.,
            Suda,Y. and Aizawa,S.
  TITLE     cfm is a novel gene uniquely expressed in developing forebrain and
            midbrain, but its null mutant exhibits no obvious phenotype
  JOURNAL   Gene Expr Patterns 5 (3), 439-444 (2005)
   PUBMED   15661651
  REMARK    GeneRIF: cfm does not have any known functional domains, but is
            conserved in human, chick, Xenopus and zebrafish. A cfm null mutant
            was live-born without any apparent defects.
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC139377.4.
            
            On Aug 22, 2018 this sequence version replaced NM_028443.2.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC053444.1, AK014112.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-291               AC139377.4         97763-98053
            292-401             AC139377.4         104687-104796
            402-1677            AC139377.4         105587-106862
FEATURES             Location/Qualifiers
     source          1..1677
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="5"
                     /map="5 63.95 cM"
     gene            1..1677
                     /gene="Rflna"
                     /gene_synonym="3110032G18Rik; cfm; cfm2; Fam101a"
                     /note="refilin A"
                     /db_xref="GeneID:73121"
                     /db_xref="MGI:MGI:1920371"
     exon            1..291
                     /gene="Rflna"
                     /gene_synonym="3110032G18Rik; cfm; cfm2; Fam101a"
                     /inference="alignment:Splign:2.1.0"
     CDS             121..735
                     /gene="Rflna"
                     /gene_synonym="3110032G18Rik; cfm; cfm2; Fam101a"
                     /note="protein FAM101A; family with sequence similarity
                     101, member A; refilinA; regulator of filamin protein A;
                     filamin-interacting protein FAM101A"
                     /codon_start=1
                     /product="refilin-A"
                     /protein_id="NP_082719.1"
                     /db_xref="CCDS:CCDS19682.1"
                     /db_xref="GeneID:73121"
                     /db_xref="MGI:MGI:1920371"
                     /translation="MVGHLHLQAMGDTREQSRDGLLDSPDSGLPPSPSPSPPFYALSP
                     GTLDTRTTTEAPAAPSLFQTPPALEMRSRLLPVFFGESIEVDPEPAHEIRCNSEITYA
                     SERYFRDKIFYAPVPTVTAYSETIVAAPNCTWRSYRSQLTLEPRPRALRFGSTAIIFP
                     KLARSSFRTTLHCSLGQPRHWYSSSLQLRRCGDPTPGPSCPDVL"
     exon            292..401
                     /gene="Rflna"
                     /gene_synonym="3110032G18Rik; cfm; cfm2; Fam101a"
                     /inference="alignment:Splign:2.1.0"
     exon            402..1677
                     /gene="Rflna"
                     /gene_synonym="3110032G18Rik; cfm; cfm2; Fam101a"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1655..1660
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Rflna"
                     /gene_synonym="3110032G18Rik; cfm; cfm2; Fam101a"
                     /note="hexamer: AATAAA"
     polyA_site      1677
                     /gene="Rflna"
                     /gene_synonym="3110032G18Rik; cfm; cfm2; Fam101a"
                     /note="major polyA site"
ORIGIN      
        1 gcatttgcat caggagcggg tctcagctgg agccacaggc cggagcctcc ttgttgctcc
       61 tctggctcag tggtggcggg gacccgagct gctggggccc acgccccgcg cccgccagtc
      121 atggtgggtc acctgcatct gcaggccatg ggggacacgc gggagcagag ccgcgacggc
      181 ttgctggaca gtcccgattc aggactgccc cccagtccca gtcctagccc gcccttctac
      241 gccctgtcgc caggcaccct ggacacccgg accaccactg aagctccagc ggctccttcc
      301 ctcttccaaa ctcccccagc tctggagatg aggtcacggt tgctgcctgt gttctttggg
      361 gagagcatcg aggtggaccc agaacccgca catgaaatcc gctgcaactc tgagatcacc
      421 tacgcctcag agagatactt ccgagacaag atcttctacg ctccagtgcc cacggtcacg
      481 gcctacagtg agaccatagt ggcggcgccc aactgcacct ggcggagcta ccgcagccag
      541 ctgaccctgg agcctcgccc acgggccctg cggttcggga gcaccgccat catcttcccc
      601 aaactggccc gcagctcctt ccgcaccacc ctgcactgca gcctcggcca gcctcggcac
      661 tggtactcct ccagcctgca gctgcggcgg tgcggggacc ctacgcccgg tcccagctgt
      721 cctgatgtac tctgaggagt ccagtctctg aggaggacct gagtgtggga gaggttcagg
      781 aaagatggcc cggctaccac cacaggttag gctggctgtg ccggagctcc agcctagagg
      841 agtctgtgaa tgcatctttc attagccttt agaggctcta tggccttaag ggcagggcca
      901 aacatgtcct ggtgtgccct tgaggcaaag atggccctat gtagcacagg gcactcagcc
      961 atggcctggc tcgaaacctc attcttggag aggcttgttt ccaaaatagg ccattaaaaa
     1021 aaaaaaaaaa acgctcattc cagctgagaa ccgcaggtgc gtgcggaggg gttgagctaa
     1081 ctttaccttg acctgagatg gcaaaggctg ggggtaccca gaacacattg tctgctgtgc
     1141 agggcgcagc cctccagggc ggcccacatg tgccccacaa gacgcattcc agactagctt
     1201 agaactcttg agcctcaaag ctctctggca ggtgccctgg gaggcgtcaa agcaaatgag
     1261 gggacacggc caataactgc ctatggctga ctctggactt gagcctatgg cagggctcag
     1321 aaccccaaga gaagcggagt ctgtttttct tggcctcccg ttcttgctta ggatggatcc
     1381 tacagttaca ccagtttccc acaacctggt gctgtcccat ggtgcccagg ctaaaatgag
     1441 tccccgagtc tactttagag gtggagatgt ccctttgtct caattgtcca gtagctagaa
     1501 acctacctac tgccgctgtg gtggcccaga gggaagggac attctttgtg gggcaaacag
     1561 aacctaaatg actgatagat ttctgttcat ctattagctt atctgaggtg ctccctggtt
     1621 aaaagaacag cctaagaaat tagtgaatta tcttaataaa atatacccac acagcca
//
