LOCUS       NM_178916               2807 bp    mRNA    linear   ROD 01-JUN-2024
DEFINITION  Mus musculus Rieske (Fe-S) domain containing (Rfesd), transcript
            variant 1, mRNA.
ACCESSION   NM_178916 XM_889146 XM_898406 XM_909326
VERSION     NM_178916.5
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2807)
  AUTHORS   Korde,A.S., Yadav,V.R., Zheng,Y.M. and Wang,Y.X.
  TITLE     Primary role of mitochondrial Rieske iron-sulfur protein in hypoxic
            ROS production in pulmonary artery myocytes
  JOURNAL   Free Radic Biol Med 50 (8), 945-952 (2011)
   PUBMED   21238580
  REMARK    GeneRIF: findings together provide novel evidence that mitochondria
            are the direct hypoxic targets in PASMCs, in which Rieske
            iron-sulfur protein in complex III may serve as an essential,
            primary molecule that mediates the hypoxic ROS generation
REFERENCE   2  (bases 1 to 2807)
  AUTHORS   Levin,E.J., Elsen,N.L., Seder,K.D., McCoy,J.G., Fox,B.G. and
            Phillips,G.N. Jr.
  TITLE     X-ray structure of a soluble Rieske-type ferredoxin from Mus
            musculus
  JOURNAL   Acta Crystallogr D Biol Crystallogr 64 (Pt 9), 933-940 (2008)
   PUBMED   18703841
  REMARK    GeneRIF: mouse Rieske-type ferredoxin was shown to be capable of
            accepting electrons from both eukaryotic and prokaryotic
            oxidoreductases, although it was unable to serve as an electron
            donor for a bacterial monooxygenase complex.
REFERENCE   3  (bases 1 to 2807)
  AUTHORS   Kotarsky,H., Tabasum,I., Mannisto,S., Heikinheimo,M., Hansson,S.
            and Fellman,V.
  TITLE     BCS1L is expressed in critical regions for neural development
            during ontogenesis in mice
  JOURNAL   Gene Expr Patterns 7 (3), 266-273 (2007)
   PUBMED   17049929
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK083705.1 and AK040255.1.
            
            On Aug 20, 2008 this sequence version replaced NM_178916.4.
            
            Transcript Variant: This variant (1) represents the longest
            transcript.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK083705.1, AK029602.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164134, SAMN01164135
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-1260              AK083705.1         2-1261
            1261-1261           AK040255.1         766-766
            1262-2807           AK083705.1         1263-2808
FEATURES             Location/Qualifiers
     source          1..2807
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="13"
                     /map="13 40.95 cM"
     gene            1..2807
                     /gene="Rfesd"
                     /gene_synonym="D030068K09"
                     /note="Rieske (Fe-S) domain containing"
                     /db_xref="GeneID:218341"
                     /db_xref="MGI:MGI:2145198"
     exon            1..1042
                     /gene="Rfesd"
                     /gene_synonym="D030068K09"
                     /inference="alignment:Splign:2.1.0"
     exon            1043..1218
                     /gene="Rfesd"
                     /gene_synonym="D030068K09"
                     /inference="alignment:Splign:2.1.0"
     CDS             1044..1517
                     /gene="Rfesd"
                     /gene_synonym="D030068K09"
                     /codon_start=1
                     /product="Rieske domain-containing protein"
                     /protein_id="NP_849247.3"
                     /db_xref="CCDS:CCDS26654.1"
                     /db_xref="GeneID:218341"
                     /db_xref="MGI:MGI:2145198"
                     /translation="MDPEISEQDEEKKKYTSVCVGREEDIRKSERMTAVVHDREVVIF
                     YHKGEYHAMDIRCYHSGGPLHLGEIEDFNGQSCIVCPWHKYKITLATGEGLYQSINPK
                     DPSAKPKWCSKGVKQRIHTVKVDNGNIYVTLSKEPFKCDSDYYATGEFKVIQSSS"
     exon            1219..1253
                     /gene="Rfesd"
                     /gene_synonym="D030068K09"
                     /inference="alignment:Splign:2.1.0"
     exon            1254..2807
                     /gene="Rfesd"
                     /gene_synonym="D030068K09"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1544..1549
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Rfesd"
                     /gene_synonym="D030068K09"
                     /note="hexamer: AATAAA"
     polyA_site      1575
                     /gene="Rfesd"
                     /gene_synonym="D030068K09"
                     /note="major polyA site"
ORIGIN      
        1 gcacttcctg cgtccgctgg cagcggttcc gagtcctcgg gtgtctgagc agggagcgtt
       61 tggaccctcg tggactggca ttggcaagag cctcagtgaa ctgttcgcct tgacagttgg
      121 gccacagccg ggacctgcag ccatttaaat aggcttttcc gcacttgtgc cataaactat
      181 gaaagcgaat ccttctgacg tcccacgcac cccaaatatt ctcctgggat ggccgtcggg
      241 acgactgctg gttgccgtgc tgtccctagc gccgctcaat ctagcagctg cggcctgtct
      301 tcttagcaaa taaaactggt ttgagaactg ctaaagccat gggggtggct accagccttg
      361 ctgcgcttcc tgcggttgca cccagctgta tagagtagag gtgccttaac gtggttgtcc
      421 tctgcacacc ctatgataca ggcctcttag gaagcagtcc gggattcaga cgctggtgaa
      481 acgccttgtc atctttaata ccagacattg gcagtaattc gctcagctgc acggcttcat
      541 taaattgggc aagtgtttta ctttagatat ttgtgaagac aatcttgtac attagcattc
      601 ctacataaac attcagaacc atcttttccg atacatgtgt gcactgcgaa tataaaactc
      661 tctatacgtt tttgccgaac ggtttttgtg actttcaaga tgattttctt tcaggccaca
      721 tgttttttgt tttttgtttc ttttctttta taaatcgctg gctgctagtg acacgaaagt
      781 tacaccaagc aacatatgag cttacagata tttaattttg tgaggagtaa tgaacattta
      841 cacgcaaagt gtccaagcgg tagtgaaatg tagctagtca aatgtattta ttatcatcaa
      901 actgctactg actaaagcat ttcccttccc tgagcctaaa agccagggtg tcaccctgga
      961 gataagcact gtgataattt gtgggccagg tccccactct aagagtccct gagtcattgc
     1021 tcaagaggag tgacacatga gtcatggacc ctgaaatctc tgaacaagat gaggaaaaga
     1081 agaaatatac ttccgtctgt gttggcagag aagaggacat tagaaaatca gaaagaatga
     1141 cagctgttgt ccatgacaga gaagtggtca ttttctacca caaaggggaa tatcatgcta
     1201 tggacattcg ctgttaccat tctggagggc ccttacactt gggagaaatt gaggatttca
     1261 atggacaatc atgtatagtt tgcccctggc ataaatataa aatcactttg gcaacaggag
     1321 aaggattata ccagtctata aatcctaaag acccatcagc aaaacccaag tggtgttcca
     1381 aaggagtaaa gcaaaggatt cacaccgtga aggtggataa cggcaatatt tatgtgacac
     1441 tttctaagga accatttaaa tgtgactctg actattatgc cactggagaa ttcaaagtga
     1501 ttcagagttc ctcctgataa aaaatgtaca gcaacaaaaa taaaataaag taagatgtgt
     1561 gtatgtttga aaatatttta aagtaatttt gtttccgtac caaagatgga tttttttcca
     1621 acatatgtac ctgtgtcttg tcaggcaggg gctgcagaga tgggccagtg gctaagggct
     1681 catgctgttc tttcagagca cctgaattca gttcctagca cttatataaa gtggctcaaa
     1741 gttccctatg atctgattcc ccctccaagg gatgatgccc tcttctggtc tctgtgggca
     1801 cctgcacaca caagtcattt acacataaat aaaaataaaa gcagatattt tttaaagtct
     1861 taaatctgaa aagtttaaaa acacatttac tttagtatga cttcagggcc cccacccagg
     1921 tcaacaggat acattccata tttctcagga ctgattggca tctgtacatt ataggtcaac
     1981 aggatacatt ccatatttct caggactgat tggcatctgt acattatagg tcaacaggat
     2041 acattccata tttctcagga ctgattggca tctgtacatt ataggcttga gatgatcagg
     2101 ttaagaagca taaagataac ttagagtaaa cacagttgac agcagataaa gcagaaaact
     2161 taacaggaaa agtgtaaatg aggcaaagac ttgtttcccc aatcacagcg tgttttggaa
     2221 agttttcata attcaaactc agtcgcttca acagttccca gcagtcctct gttcctcttg
     2281 cattgatgtg tccacaggtt gctgacttcc gtatttaatt acactattta caattttaaa
     2341 ggtagaattt aaacacactg agatccttga attttaggtt gtatattata catttgctta
     2401 caaatgttta gcacatgttt tacatgttaa aactgccacc aaaaattgag gccaatgtat
     2461 atgttaaact taaaaatgag aaacttaaag cttgttccag cattctgagg cagaggtaga
     2521 aggatctctg cgaattagag gctaacctgg gctacatagt gagttctaaa cagccagcac
     2581 tacatagtga gaccctatca aagaaggggg ctgggaagtt atagatagga agacccagga
     2641 aaacgtagct tggtcttaac atattctctt atcagggctg attcttgatg taaaaagcca
     2701 cgaacagtaa caccctaacc aagatatatg taaagtctcc tattcaacaa accaaagaac
     2761 tttacttaca tgaacctttc aaataaaagt ttaaaagaat tttagag
//
