LOCUS       NM_027009               1222 bp    mRNA    linear   ROD 14-JUN-2024
DEFINITION  Mus musculus replication factor C (activator 1) 3 (Rfc3),
            transcript variant 1, mRNA.
ACCESSION   NM_027009 XM_906911 XM_977036 XM_989579
VERSION     NM_027009.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1222)
  AUTHORS   Bedogni,F. and Hevner,R.F.
  TITLE     Cell-Type-Specific Gene Expression in Developing Mouse Neocortex:
            Intermediate Progenitors Implicated in Axon Development
  JOURNAL   Front Mol Neurosci 14, 686034 (2021)
   PUBMED   34321999
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1222)
  AUTHORS   Gray,S., Santiago,E.R., Chappie,J.S. and Cohen,P.E.
  TITLE     Cyclin N-Terminal Domain-Containing-1 Coordinates Meiotic Crossover
            Formation with Cell-Cycle Progression in a Cyclin-Independent
            Manner
  JOURNAL   Cell Rep 32 (1), 107858 (2020)
   PUBMED   32640224
REFERENCE   3  (bases 1 to 1222)
  AUTHORS   Blackshaw,S., Harpavat,S., Trimarchi,J., Cai,L., Huang,H.,
            Kuo,W.P., Weber,G., Lee,K., Fraioli,R.E., Cho,S.H., Yung,R.,
            Asch,E., Ohno-Machado,L., Wong,W.H. and Cepko,C.L.
  TITLE     Genomic analysis of mouse retinal development
  JOURNAL   PLoS Biol 2 (9), E247 (2004)
   PUBMED   15226823
REFERENCE   4  (bases 1 to 1222)
  AUTHORS   Gonzalez,J., Orlofsky,A. and Prystowsky,M.B.
  TITLE     A1 is a growth-permissive antiapoptotic factor mediating
            postactivation survival in T cells
  JOURNAL   Blood 101 (7), 2679-2685 (2003)
   PUBMED   12406903
  REMARK    GeneRIF: A1 is a growth-permissive antiapoptotic factor mediating
            postactivation survival in T cells.
REFERENCE   5  (bases 1 to 1222)
  AUTHORS   Bunz,F., Kobayashi,R. and Stillman,B.
  TITLE     cDNAs encoding the large subunit of human replication factor C
  JOURNAL   Proc Natl Acad Sci U S A 90 (23), 11014-11018 (1993)
   PUBMED   8248204
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC120011.16.
            
            On Mar 9, 2023 this sequence version replaced NM_027009.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK167047.1, AK145126.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164139, SAMN01164140
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-143               AC120011.16        79119-79261
            144-281             AC120011.16        80318-80455
            282-349             AC120011.16        82015-82082
            350-447             AC120011.16        82791-82888
            448-629             AC120011.16        84628-84809
            630-766             AC120011.16        85401-85537
            767-865             AC120011.16        85616-85714
            866-935             AC120011.16        86547-86616
            936-1222            AC120011.16        87224-87510
FEATURES             Location/Qualifiers
     source          1..1222
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="5"
                     /map="5 90.18 cM"
     gene            1..1222
                     /gene="Rfc3"
                     /gene_synonym="2810416I22Rik; 38kDa; Recc3"
                     /note="replication factor C (activator 1) 3"
                     /db_xref="GeneID:69263"
                     /db_xref="MGI:MGI:1916513"
     exon            1..143
                     /gene="Rfc3"
                     /gene_synonym="2810416I22Rik; 38kDa; Recc3"
                     /inference="alignment:Splign:2.1.0"
     CDS             57..1127
                     /gene="Rfc3"
                     /gene_synonym="2810416I22Rik; 38kDa; Recc3"
                     /note="isoform 1 is encoded by transcript variant 1;
                     replication factor C 3; replication factor C subunit 3;
                     RFC38; A1 38 kDa subunit; RF-C 38 kDa subunit; activator 1
                     subunit 3; activator 1 38 kDa subunit; replication factor
                     C 38 kDa subunit; replication factor C, 38 kDa"
                     /codon_start=1
                     /product="replication factor C subunit 3 isoform 1"
                     /protein_id="NP_081285.1"
                     /db_xref="CCDS:CCDS39413.1"
                     /db_xref="GeneID:69263"
                     /db_xref="MGI:MGI:1916513"
                     /translation="MSLWVDKYRPSSLARLDYHKEQAAQLRNLVQCGDFPHLLVYGPS
                     GAGKKTRIMCILRELYGIGVEKLRIEHQTITTPSKKKIEISTIASNYHLEVNPSDAGN
                     SDRVVIQEMLKTVAQSQQLETSSQRDFKVVLLTEVDKLTKDAQHALRRTMEKYMSTCR
                     LILCCNSTSKVIPPIRSRCLAVRVPAPSIEDICSVLSTVCRKEGLALPSTLARRLAEK
                     SCRNLRKALLMCEACRVQQYPFTEDQEIPETDWEVYLRETANAIVSQQTPQRLLEVRG
                     RLYELLTHCIPPEIIMKGLLSELLHNCDGQLKGEVAQMAAYYEHRLQLGSKAIYHLEA
                     FVAKFMALYKKFMEDGLEGMMF"
     exon            144..281
                     /gene="Rfc3"
                     /gene_synonym="2810416I22Rik; 38kDa; Recc3"
                     /inference="alignment:Splign:2.1.0"
     exon            282..349
                     /gene="Rfc3"
                     /gene_synonym="2810416I22Rik; 38kDa; Recc3"
                     /inference="alignment:Splign:2.1.0"
     exon            350..447
                     /gene="Rfc3"
                     /gene_synonym="2810416I22Rik; 38kDa; Recc3"
                     /inference="alignment:Splign:2.1.0"
     exon            448..629
                     /gene="Rfc3"
                     /gene_synonym="2810416I22Rik; 38kDa; Recc3"
                     /inference="alignment:Splign:2.1.0"
     exon            630..766
                     /gene="Rfc3"
                     /gene_synonym="2810416I22Rik; 38kDa; Recc3"
                     /inference="alignment:Splign:2.1.0"
     exon            767..865
                     /gene="Rfc3"
                     /gene_synonym="2810416I22Rik; 38kDa; Recc3"
                     /inference="alignment:Splign:2.1.0"
     exon            866..935
                     /gene="Rfc3"
                     /gene_synonym="2810416I22Rik; 38kDa; Recc3"
                     /inference="alignment:Splign:2.1.0"
     exon            936..1222
                     /gene="Rfc3"
                     /gene_synonym="2810416I22Rik; 38kDa; Recc3"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1196..1201
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Rfc3"
                     /gene_synonym="2810416I22Rik; 38kDa; Recc3"
                     /note="hexamer: AATAAA"
     polyA_site      1222
                     /gene="Rfc3"
                     /gene_synonym="2810416I22Rik; 38kDa; Recc3"
                     /note="major polyA site"
ORIGIN      
        1 gcgggaaaac tctactgtct aagcggcggg tccgctggtg cgactgtgga gcggtcatga
       61 gcctctgggt ggacaagtac cggccgagct cccttgcccg gctggactat cataaggaac
      121 aggcagcaca gctgcgcaac ctggtgcagt gtggagactt tcctcacctc ttagtatatg
      181 gaccatcagg tgctggaaaa aagacaagaa ttatgtgtat tctacgtgaa ctttatggta
      241 tcggggtgga aaaactgaga attgagcatc agactatcac aaccccgtct aaaaaaaaaa
      301 ttgaaatcag caccattgca agcaactacc accttgaagt taatcccagt gatgcgggga
      361 acagcgaccg agttgtaatt caggagatgc tgaagacagt ggcccagtca caacaacttg
      421 aaaccagctc acaaagagac ttcaaagtgg tattattgac agaggtggac aaactcacaa
      481 aggatgctca gcatgcctta cgcagaacta tggagaaata catgtctacc tgcaggctca
      541 tcttgtgctg caattccaca tccaaggtga tacccccgat ccgaagcagg tgcctggcag
      601 ttcgtgtgcc tgctcccagc atcgaagata tttgcagtgt actatccact gtctgcagga
      661 aggaaggtct ggctctccct tcgacattgg cccgtaggct ggccgagaag tcatgccgaa
      721 acctcaggaa agccttactt atgtgtgagg cctgcagagt gcagcaatac ccttttacgg
      781 aagaccaaga aatcccagag acagactggg aggtgtatct gagggagacc gcaaatgcta
      841 ttgtcagtca gcagacgcca cagaggctcc ttgaagtccg tggaaggctc tatgagcttc
      901 taactcattg tattcctcct gagattataa tgaagggcct cctctcagaa ctcctccata
      961 actgtgatgg gcagctgaaa ggggaagtgg cacagatggc agcctactat gagcaccgac
     1021 tacagctggg cagcaaagcc atttatcatt tggaagcatt tgtggcgaag tttatggcac
     1081 tttataagaa gttcatggag gatggactgg aaggcatgat gttctgacag ccagcagctc
     1141 ctccaagcac aacagatgcc ttgtttatat aaatttatcc tgggactttg ggtataataa
     1201 actagcttta cctagtaatg ta
//
