LOCUS       NM_025577                683 bp    mRNA    linear   ROD 02-MAY-2024
DEFINITION  Mus musculus required for excision 1-B domain containing (Rex1bd),
            transcript variant 1, mRNA.
ACCESSION   NM_025577 XM_979407
VERSION     NM_025577.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 683)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC157774.5, AK013181.1 and AA217756.1.
            
            On Oct 24, 2017 this sequence version replaced NM_025577.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: CA318921.1, BC028495.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164132, SAMN01164134
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-13                AC157774.5         141148-141160
            14-670              AK013181.1         2-658
            671-683             AA217756.1         355-367
FEATURES             Location/Qualifiers
     source          1..683
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="8"
                     /map="8 34.15 cM"
     gene            1..683
                     /gene="Rex1bd"
                     /gene_synonym="2810428I15Rik"
                     /note="required for excision 1-B domain containing"
                     /db_xref="GeneID:66462"
                     /db_xref="MGI:MGI:1913712"
     exon            1..91
                     /gene="Rex1bd"
                     /gene_synonym="2810428I15Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             20..529
                     /gene="Rex1bd"
                     /gene_synonym="2810428I15Rik"
                     /note="isoform 1 is encoded by transcript variant 1;
                     uncharacterized protein C19orf60 homolog; required for
                     excision 1-B domain-containing protein"
                     /codon_start=1
                     /product="required for excision 1-B domain-containing
                     protein isoform 1"
                     /protein_id="NP_079853.1"
                     /db_xref="CCDS:CCDS22370.1"
                     /db_xref="GeneID:66462"
                     /db_xref="MGI:MGI:1913712"
                     /translation="MLTAATEVLAAADGPGSAESAWAWRDAPIATLVQRIQQLQNERA
                     QAFRRLDQAHRQYLLSGQHYDFPSYRSVVHEVTQAFAAASREVLAVEAELAGPRAQPV
                     LARHVRSLQELEQTRLATVALLQVMGTPGVSEQDPEKLHQLKIKVIKTMEAIGEVLQE
                     LRFDAESAE"
     exon            92..174
                     /gene="Rex1bd"
                     /gene_synonym="2810428I15Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            175..379
                     /gene="Rex1bd"
                     /gene_synonym="2810428I15Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            380..456
                     /gene="Rex1bd"
                     /gene_synonym="2810428I15Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            457..671
                     /gene="Rex1bd"
                     /gene_synonym="2810428I15Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      650..655
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Rex1bd"
                     /gene_synonym="2810428I15Rik"
                     /note="hexamer: AATAAA"
     polyA_site      671
                     /gene="Rex1bd"
                     /gene_synonym="2810428I15Rik"
                     /note="major polyA site"
ORIGIN      
        1 gccacttgac tgcgcagtca tgctcaccgc cgccacagag gtgttggctg ctgcagacgg
       61 tcccgggtct gcggagtccg cgtgggcctg gagagacgcc ccgatcgcta cactggtgca
      121 gaggattcag cagcttcaga atgaacgcgc acaggccttc cgccgtctag accaagctca
      181 ccgtcagtac ctgctcagtg gtcagcacta tgacttcccg agttaccgga gtgtcgtgca
      241 cgaggtgacc caggccttcg ccgctgcctc gcgggaggta ttggcagtgg aagcagagtt
      301 ggcagggcct cgagcgcaac cggtgctcgc ccgccacgtg cgcagcctgc aggagctaga
      361 acagacgcgc ctggccacgg tggcactgtt gcaggtgatg gggacaccag gagtgtcaga
      421 acaggaccct gaaaagttgc accagctgaa aataaaggta attaaaacca tggaggcgat
      481 cggcgaggtt ctgcaggaac tcaggtttga tgcggaatct gccgagtgag ggcggctccc
      541 cagggaccag aggaagccgg gaaaagaggc ccatggcgtc gagcccagcc ctgaccgcca
      601 gctggctgag gtcgtgccct gctgggctgc cctccaatgt gcctcacgca ataaagaatt
      661 ctccctctgc aaaaaaaaaa aaa
//
