LOCUS       NM_001080780            7341 bp    mRNA    linear   ROD 11-FEB-2025
DEFINITION  Mus musculus ret proto-oncogene (Ret), transcript variant 4, mRNA.
ACCESSION   NM_001080780
VERSION     NM_001080780.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 7341)
  AUTHORS   Huey,E.L., Turecek,J., Delisle,M.M., Mazor,O., Romero,G.E., Dua,M.,
            Sarafis,Z.K., Hobble,A., Booth,K.T., Goodrich,L.V., Corey,D.P. and
            Ginty,D.D.
  TITLE     The auditory midbrain mediates tactile vibration sensing
  JOURNAL   Cell 188 (1), 104-120 (2025)
   PUBMED   39701100
REFERENCE   2  (bases 1 to 7341)
  AUTHORS   Franks,N.E. and Allen,B.L.
  TITLE     Hedgehog-dependent and hedgehog-independent roles for growth arrest
            specific 1 in mammalian kidney morphogenesis
  JOURNAL   Development 151 (24) (2024)
   PUBMED   39629522
REFERENCE   3  (bases 1 to 7341)
  AUTHORS   Lemmetyinen,T.T., Viitala,E.W., Wartiovaara,L., Paivinen,P.,
            Virtanen,H.T., Pentinmikko,N., Katajisto,P., Makela,T.P.,
            Wang,T.C., Andressoo,J.O. and Ollila,S.
  TITLE     Mesenchymal GDNF promotes intestinal enterochromaffin cell
            differentiation
  JOURNAL   iScience 27 (12), 111246 (2024)
   PUBMED   39634560
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 7341)
  AUTHORS   Shiohama,T., Uchikawa,H., Nitta,N., Takatani,T., Matsuda,S.,
            Ortug,A., Takahashi,E., Sawada,D., Shimizu,E., Fujii,K., Aoki,I.
            and Hamada,H.
  TITLE     Brain morphological analysis in mice with hyperactivation of the
            hedgehog signaling pathway
  JOURNAL   Front Neurosci 18, 1449673 (2024)
   PUBMED   39290714
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 7341)
  AUTHORS   Virtanen,H.T., Choopanian,P., Porokuokka,L.L., Forsgard,R.,
            Garton,D.R., Olfat,S., Korpela,R., Mirzaie,M. and Andressoo,J.O.
  TITLE     Interindividual Variation in Gut Nitrergic Neuron Density Is
            Regulated By GDNF Levels and ETV1
  JOURNAL   Cell Mol Gastroenterol Hepatol 18 (6), 101405 (2024)
   PUBMED   39299667
REFERENCE   6  (bases 1 to 7341)
  AUTHORS   Dudley,A.T., Lyons,K.M. and Robertson,E.J.
  TITLE     A requirement for bone morphogenetic protein-7 during development
            of the mammalian kidney and eye
  JOURNAL   Genes Dev 9 (22), 2795-2807 (1995)
   PUBMED   7590254
REFERENCE   7  (bases 1 to 7341)
  AUTHORS   Jones,P.S., Savory,R., Barratt,P., Bell,A.R., Gray,T.J.,
            Jenkins,N.A., Gilbert,D.J., Copeland,N.G. and Bell,D.R.
  TITLE     Chromosomal localisation, inducibility, tissue-specific expression
            and strain differences in three murine
            peroxisome-proliferator-activated-receptor genes
  JOURNAL   Eur J Biochem 233 (1), 219-226 (1995)
   PUBMED   7588749
REFERENCE   8  (bases 1 to 7341)
  AUTHORS   Holmberg,M., Leonardsson,G. and Ny,T.
  TITLE     The species-specific differences in the cAMP regulation of the
            tissue-type plasminogen activator gene between rat, mouse and human
            is caused by a one-nucleotide substitution in the cAMP-responsive
            element of the promoters
  JOURNAL   Eur J Biochem 231 (2), 466-474 (1995)
   PUBMED   7543410
REFERENCE   9  (bases 1 to 7341)
  AUTHORS   Iwamoto,T., Takahashi,M., Ohbayashi,M. and Nakashima,I.
  TITLE     The ret oncogene can induce melanogenesis and melanocyte
            development in Wv/Wv mice
  JOURNAL   Exp Cell Res 200 (2), 410-415 (1992)
   PUBMED   1374037
REFERENCE   10 (bases 1 to 7341)
  AUTHORS   Takahashi,M., Buma,Y., Iwamoto,T., Inaguma,Y., Ikeda,H. and Hiai,H.
  TITLE     Cloning and expression of the ret proto-oncogene encoding a
            tyrosine kinase with two potential transmembrane domains
  JOURNAL   Oncogene 3 (5), 571-578 (1988)
   PUBMED   3078962
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC156396.8, BC059012.1 and AC135861.5.
            
            Transcript Variant: This variant (4) represents the longer
            transcript but encodes the shorter isoform (c). This isoform is
            also known as Ret9.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC059012.1, AK051633.1 [ECO:0000332]
            RNAseq introns              :: mixed/partial sample support
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000350]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-26                AC156396.8         66581-66606         c
            27-4523             BC059012.1         1-4497
            4524-7341           AC135861.5         453-3270
FEATURES             Location/Qualifiers
     source          1..7341
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="6"
                     /map="6 55.86 cM"
     gene            1..7341
                     /gene="Ret"
                     /gene_synonym="c-Ret; PTC; RET51; RET9"
                     /note="ret proto-oncogene"
                     /db_xref="GeneID:19713"
                     /db_xref="MGI:MGI:97902"
     exon            1..684
                     /gene="Ret"
                     /gene_synonym="c-Ret; PTC; RET51; RET9"
                     /inference="alignment:Splign:2.1.0"
     CDS             612..3833
                     /gene="Ret"
                     /gene_synonym="c-Ret; PTC; RET51; RET9"
                     /EC_number="2.7.10.1"
                     /note="isoform c precursor is encoded by transcript
                     variant 4; proto-oncogene tyrosine-protein kinase receptor
                     Ret; proto-oncogene c-Ret"
                     /codon_start=1
                     /product="proto-oncogene tyrosine-protein kinase receptor
                     Ret isoform c precursor"
                     /protein_id="NP_001074249.1"
                     /db_xref="CCDS:CCDS39608.1"
                     /db_xref="GeneID:19713"
                     /db_xref="MGI:MGI:97902"
                     /translation="MAKATSGAAGLGLKLILLLPLLGEAPLGLYFSRDAYWERLYVDQ
                     PAGTPLLYVHALRDAPGEVPSFRLGQHLYGVYRTRLHENDWIRINETTGLLYLNQSLD
                     HSSWEQLSIRNGGFPLLTIFLQVFLGSTAQREGECHWPGCTRVYFSFINDTFPNCSSF
                     KAQDLCIPETAVSFRVRENRPPGTFYHFHMLPVQFLCPNISVKYSLLGGDSLPFRCDP
                     DCLEVSTRWALDRELREKYVLEALCIVAGPGANKETVTLSFPVTVYDEDDSAPTFSGG
                     VGTASAVVEFKRKEGTVVATLQVFDADVVPASGELVRRYTNTLLSGDSWAQQTFRVEH
                     SPIETLVQVNNNSVRATMHNYKLILNRSLSISESRVLQLAVLVNDSDFQGPGAGGILV
                     LHFNVSVLPVTLNLPRAYSFPVNKRARRYAQIGKVCVENCQEFSGVSIQYKLQPSSIN
                     CTALGVVTSPEDTSGTLFVNDTEALRRPECTKLQYTVVATDRQTRRQTQASLVVTVEG
                     TSITEEVGCPKSCAVNKRRPECEECGGLGSPTGRCEWRQGDGKGITRNFSTCSPSTRT
                     CPDGHCDAVESRDANICPQDCLRADIVGGHERGERQGIKAGYGICNCFPDEKKCFCEP
                     EDSQGPLCDALCRTIITAALFSLIISILLSIFCVCHHHKHGHKPPIASAEMTFCRPAQ
                     GFPISYSSSGTRRPSLDSTENQVPVDSFKIPEDPKWEFPRKNLVLGKTLGEGEFGKVV
                     KATAFRLKGRAGYTTVAVKMLKENASQSELRDLLSEFNLLKQVNHPHVIKLYGACSQD
                     GPLLLIVEYAKYGSLRGFLRDSRKIGPAYVSGGGSRNSSSLDHPDERVLTMGDLISFA
                     WQISRGMQYLAEMKLVHRDLAARNILVAEGRKMKISDFGLSRDVYEEDSYVKKSKGRI
                     PVKWMAIESLFDHIYTTQSDVWSFGVLLWEIVTLGGNPYPGIPPERLFNLLKTGHRME
                     RPDNCSEEMYRLMLQCWKQEPDKRPVFADISKDLEKMMVKSRDYLDLAASTPSDSLLY
                     DDGLSEEETPLVDCNNAPLPRSLPSTWIENKLYGRISHAFTRF"
     exon            685..948
                     /gene="Ret"
                     /gene_synonym="c-Ret; PTC; RET51; RET9"
                     /inference="alignment:Splign:2.1.0"
     exon            949..1236
                     /gene="Ret"
                     /gene_synonym="c-Ret; PTC; RET51; RET9"
                     /inference="alignment:Splign:2.1.0"
     exon            1237..1481
                     /gene="Ret"
                     /gene_synonym="c-Ret; PTC; RET51; RET9"
                     /inference="alignment:Splign:2.1.0"
     exon            1482..1677
                     /gene="Ret"
                     /gene_synonym="c-Ret; PTC; RET51; RET9"
                     /inference="alignment:Splign:2.1.0"
     exon            1678..1880
                     /gene="Ret"
                     /gene_synonym="c-Ret; PTC; RET51; RET9"
                     /inference="alignment:Splign:2.1.0"
     exon            1881..2139
                     /gene="Ret"
                     /gene_synonym="c-Ret; PTC; RET51; RET9"
                     /inference="alignment:Splign:2.1.0"
     exon            2140..2265
                     /gene="Ret"
                     /gene_synonym="c-Ret; PTC; RET51; RET9"
                     /inference="alignment:Splign:2.1.0"
     exon            2266..2376
                     /gene="Ret"
                     /gene_synonym="c-Ret; PTC; RET51; RET9"
                     /inference="alignment:Splign:2.1.0"
     exon            2377..2496
                     /gene="Ret"
                     /gene_synonym="c-Ret; PTC; RET51; RET9"
                     /inference="alignment:Splign:2.1.0"
     exon            2497..2750
                     /gene="Ret"
                     /gene_synonym="c-Ret; PTC; RET51; RET9"
                     /inference="alignment:Splign:2.1.0"
     exon            2751..2898
                     /gene="Ret"
                     /gene_synonym="c-Ret; PTC; RET51; RET9"
                     /inference="alignment:Splign:2.1.0"
     exon            2899..3006
                     /gene="Ret"
                     /gene_synonym="c-Ret; PTC; RET51; RET9"
                     /inference="alignment:Splign:2.1.0"
     exon            3007..3221
                     /gene="Ret"
                     /gene_synonym="c-Ret; PTC; RET51; RET9"
                     /inference="alignment:Splign:2.1.0"
     exon            3222..3344
                     /gene="Ret"
                     /gene_synonym="c-Ret; PTC; RET51; RET9"
                     /inference="alignment:Splign:2.1.0"
     exon            3345..3415
                     /gene="Ret"
                     /gene_synonym="c-Ret; PTC; RET51; RET9"
                     /inference="alignment:Splign:2.1.0"
     exon            3416..3553
                     /gene="Ret"
                     /gene_synonym="c-Ret; PTC; RET51; RET9"
                     /inference="alignment:Splign:2.1.0"
     exon            3554..3653
                     /gene="Ret"
                     /gene_synonym="c-Ret; PTC; RET51; RET9"
                     /inference="alignment:Splign:2.1.0"
     exon            3654..7341
                     /gene="Ret"
                     /gene_synonym="c-Ret; PTC; RET51; RET9"
                     /inference="alignment:Splign:2.1.0"
     regulatory      4465..4470
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Ret"
                     /gene_synonym="c-Ret; PTC; RET51; RET9"
                     /note="hexamer: AGTAAA"
     polyA_site      4487
                     /gene="Ret"
                     /gene_synonym="c-Ret; PTC; RET51; RET9"
                     /note="major polyA site"
     regulatory      4505..4510
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Ret"
                     /gene_synonym="c-Ret; PTC; RET51; RET9"
                     /note="hexamer: ATTAAA"
     polyA_site      4524
                     /gene="Ret"
                     /gene_synonym="c-Ret; PTC; RET51; RET9"
     regulatory      7318..7323
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Ret"
                     /gene_synonym="c-Ret; PTC; RET51; RET9"
                     /note="hexamer: AATAAA"
     polyA_site      7340
                     /gene="Ret"
                     /gene_synonym="c-Ret; PTC; RET51; RET9"
ORIGIN      
        1 gacatcattc tagactctgg gtctctgcga gtataggtga ccagtcggcc cagacgccga
       61 atcttctgtg ttgctctttc tgggcggcgg gaaaggacta acagaaacag caagcgagac
      121 gcacggggtg agaaagtggc tatgccggca aatgatcatg gatccaggtt acctttagta
      181 gaccagcacc cgcaccacaa cccacacgca cccagctccg acccgcgctc atctagagag
      241 gaaatagagg ttcccctagc agtcgggtgc cgccccacct tgccccacac agtacctgga
      301 gccccgcccc tccacacaca cccgcacccc tggtcccgcc cctctcgctg ccactccctc
      361 tgcgccctgc cctgccccag tccgctcccc gggcgcaggc agcgcaggtc tctcatcagt
      421 accgcaaccg gagccgtgca agcaacagca gagagcggct ccgagtccgc agctgggagt
      481 cgcgcccgga cgcaacgcgc ccgcagtgcc cgctgcgccc gggctggcat ggggaggccc
      541 ggctgagcgc cgcaccccac cgccgccgag acccgcctgc tcctcaaccg cggccctcgc
      601 gcgcacgggc gatggcgaaa gcgacgtccg gcgccgcagg gctggggctg aagctgattt
      661 tgctcctgcc gctgctagga gaagccccac tgggcctcta tttctcaagg gatgcttact
      721 gggagaggct gtatgtagac cagccagctg gcacacctct gctctatgtc catgccctac
      781 gggatgcccc tggagaagtg ccgagcttcc gcctgggcca gcatctctat ggcgtctacc
      841 gtacacggct gcatgagaat gactggatcc gcatcaatga gactactggc cttctctacc
      901 tcaatcagag cctggaccac agttcctggg aacagctcag catccgcaat ggtggtttcc
      961 ccctgctcac catcttcctc caggtctttc tggggtccac agcccagaga gagggagaat
     1021 gccattggcc aggctgtacc cgtgtgtact tctccttcat caacgacacc ttcccaaatt
     1081 gtagctcctt caaagcccag gatctctgca tcccagagac agccgtgtcc ttccgagtca
     1141 gggagaacag gcctcctggc accttctacc acttccacat gttacccgtg cagttccttt
     1201 gtcccaacat cagtgtgaag tacagtctct taggagggga tagtctgccc ttccgttgtg
     1261 acccagactg cctggaggtg agcactcgct gggccctgga tcgagagctc cgggagaagt
     1321 atgtgctgga ggctttgtgc atagtggcag gccctggtgc caacaaagag acggtgactc
     1381 tgtccttccc agtgacagtg tatgatgagg acgactcggc gcccaccttc tctggaggtg
     1441 tgggcactgc cagcgcggtg gtggagttta agcggaagga gggcactgtg gtggccaccc
     1501 tgcaggtgtt cgatgcagat gtggtgccag cgtctgggga gctggtgaga cggtacacaa
     1561 acacactcct ctcaggggac tcctgggccc agcagacctt ccgggtggag cattcgccca
     1621 tcgagacctt ggtccaggtc aacaacaact ccgttcgggc aaccatgcac aattacaagc
     1681 tgattctcaa caggagcctg tctatctcag agagccgagt cctgcagctc gcggtcctgg
     1741 tcaacgactc agacttccag gggcctgggg caggtggtat cctcgtcctc catttcaacg
     1801 tgtctgtact gcccgtcacc ctgaacctac ccagggccta ctccttccca gtgaataaga
     1861 gggcccgccg ctatgcccag atcgggaaag tctgtgtgga aaactgccag gagttcagcg
     1921 gtgtctccat ccagtacaag ctgcagcctt ccagcatcaa ctgcactgcc ctaggtgtgg
     1981 tcacctcacc cgaggacacc tcggggaccc tatttgtaaa tgacacagag gccctgcggc
     2041 gacctgagtg caccaagctt cagtacacgg tggtagccac tgaccggcag acccgcagac
     2101 agacccaggc ttcgctagtg gtcactgtgg aggggacatc cattactgaa gaagtaggct
     2161 gccccaagtc ctgtgcagta aacaagaggc gccccgagtg tgaggaatgt ggtggcctgg
     2221 gttctccaac tggcaggtgc gagtggcgcc agggagatgg taaagggatc accaggaact
     2281 tctccacctg ctcccccagt accaggacct gccccgacgg ccactgtgat gctgtggaga
     2341 gccgggatgc caacatttgc ccccaggact gtctccgtgc cgacattgtt ggaggacacg
     2401 agcgagggga gcgccagggc attaaagcag gctacggcat ctgcaactgt ttccctgatg
     2461 agaagaaatg cttctgcgag ccagaggaca gccagggccc actgtgtgat gcgctgtgcc
     2521 gcacgatcat cacagctgcc ctcttctccc ttatcatctc catcctgctg tccatcttct
     2581 gtgtctgcca ccaccacaag catgggcaca agccgcccat tgcatcagcg gaaatgacct
     2641 tctgccggcc ggcccagggc ttcccaatca gttattcctc ctcaggcacc cgccggccct
     2701 cactggattc cacggagaac caggttcctg tggactcttt caagatcccg gaggatccaa
     2761 agtgggaatt tcctcggaag aacttagttc ttgggaaaac tctgggagaa ggcgagtttg
     2821 gaaaagttgt caaggccaca gccttccgtc tgaaaggccg ggcaggatac accacagtgg
     2881 ctgtgaaaat gctgaaagaa aacgcctccc agagtgagtt acgagacctg ctgtctgagt
     2941 tcaaccttct gaaacaagtc aaccatccac atgtcatcaa gttgtatggg gcctgcagcc
     3001 aggatgggcc acttcttctc attgtggagt atgccaagta tggctccctg cggggattcc
     3061 tccgtgacag ccgcaagatt gggcctgcct atgtgagcgg tggaggcagc cgcaactcca
     3121 gctcgctgga ccacccagat gaaagggtac tgaccatggg tgacctcatc tccttcgcct
     3181 ggcagatctc gaggggtatg cagtacttgg cagaaatgaa gcttgtacat cgggacttag
     3241 ctgccaggaa catcttggtg gctgagggac ggaagatgaa gatttccgac tttgggctgt
     3301 cccgagatgt ttatgaggaa gattcctatg tgaagaaaag caagggccgg attcccgtca
     3361 agtggatggc aattgagtcc cttttcgatc acatctatac tactcaaagt gatgtgtggt
     3421 cctttggagt gctgctctgg gagattgtga ccctgggagg caacccctac cctggaattc
     3481 ctcctgaacg actcttcaac cttctgaaga caggccacag gatggagagg ccagacaact
     3541 gcagcgagga aatgtaccgt ctgatgctgc agtgctggaa gcaggagcca gacaagaggc
     3601 cagtgtttgc tgacatcagc aaggatctgg agaagatgat ggtcaagagc agagactact
     3661 tggacctggc tgcatccaca ccttcggact cactgctgta tgacgatggg ctctcagaag
     3721 aggagacacc cctggtggac tgtaacaatg ctcccctccc gcgctccctc ccttccacat
     3781 ggattgaaaa caaactctat ggtagaattt cacatgcatt tactagattc tagcaacgct
     3841 gtcctctctg caccatccca actctctgta acgcttttta aagagtgttt ctgatcccac
     3901 cgacaccaaa gcctcctccg aacccttttc tttgtaaata tctgactttg catctagttt
     3961 acatacattc aggcattttg cagctatgtc tttctaaaag gatgtgaaaa taagtgtcat
     4021 taccacacag cccagcaact tacgatgaca caggagaagc ggattagagc agaattctca
     4081 gggcccattg ggaagcaaat catagtactg gtgacttcga tatttaaatt tacctgatct
     4141 ggggagggag tcagttttgc cagggaaagc tggcatcccc agctatgcta tcgttgcaag
     4201 ctgggctacc cccaggctgc tcctgggctg gtgtgtgcct cgcggaagcc gaccataatc
     4261 ccacttccag ctatgtgtcc acagccgtgc agtgtggggc agcgggaaaa ccatgtgggc
     4321 cctgggcaga caccagactg ctgctttcac atcctttgca ccctaccccc atcatgatgt
     4381 tgtcactcac gaagccagtg ctaaatactg agccaatgct ttctgaaaga acatagtctg
     4441 tggtgctgtg gccttgcaat ggacagtaaa tacggctctt gccaaaactc cttctttgtc
     4501 ttggattaaa tacttgaaat tttttttctg cttcctaatc tcctcattga tgctttttga
     4561 agtcttgcag tttcaagcta aggtaggttc tttcctgcat gcttcctgag tcacaggtcc
     4621 tcactacctg ccttgtgcct acagtgctgc gggggcagcc tgtgtgtgcc ccctgtggga
     4681 aaggaagtct tcctcctccg tgttagcagg gatgacaggt gaacagcccc tagagggttc
     4741 ccactacagg aagccatata gtccagccat tcgctgatgc tttacactgt cctgggaaaa
     4801 cagttgagca tttcaccaga tctgtttcag atttgagact ctaaactcat aggctttgag
     4861 atttggtagc ctctgctaaa ttacctgtac caggagcatg taaggttgcc ccatgtagaa
     4921 cagtgttttg gaaacctggg atgcaaaacc attaatggaa ttggcacgga aagcgcaagt
     4981 tggtttaacc atcaaaggga gttttgccaa ggccttactg tctgcacatg aagtttgagt
     5041 tcttcagtgc agaacaaatt atctgttttc atttttaggc atgtcagacc cgaactggcc
     5101 tggagagagt cctgtaccac tcacgagagc cgatggcact agcactgggt tcccaagata
     5161 tgcaaatgat agtgtatatg ctaactggat ggtttcaccc tcagcggcaa aattaatgga
     5221 cacatttgat agctaacatt cctttgtgaa cggtaatgga ctcccaaggg ggaagaaaca
     5281 tgccaagagc atcaagtcca ccggcccctt tgtgcacatc atactggcca agaccagcct
     5341 taggtggcag acttgttttc tgtagtttgt tttagctggt ttccaaatgg ttttacttca
     5401 aatagctggt ggtcctccct cctggtggtc tgccctccta gcacacctgc cccattgggt
     5461 gggtgctctg agtctctggt tagatcccct ttccctttag cattgggtag cacctctgtt
     5521 ggtctgctca tcactagcca ccacgagctc tgtgtccaca tgtgtggggt ctgccattca
     5581 tgacttggat gagaaattgt acctgaactg tctgattttc ctggctgata aaaaacctac
     5641 cacgtccccc caaaaatgtt ttaacatgaa gcacacatac aaacaacatt gattgaaaaa
     5701 cctggccaga acgacctgtc cttgtctaga atgaaagcct agcataggac tgggtagttg
     5761 catccacccg ggtccactag ggctggaggg gagaagggag cctccgggct gtcctcggct
     5821 caatatatga catcctgaat atagattttt gggtttttta gccatgtagc cttttcttag
     5881 gaaaatgttt tgtttctgtc atggttaaat ggctcttaga attagcacaa tggagagatt
     5941 tggtgttgcc tttgctatat acaaggcaac tggaaagaag tgaccccaca tgacctagtc
     6001 cccctgttga gccctcggca acattcacgc tgcgtgactc cgactcactg accagaacag
     6061 ggtgaagaag cggggcattt ggagtagagt tgccttcagg tccagtattg ctgtcatcag
     6121 aggccttgag ccacaaattc tgcaccccca gcaagccagt ctgcagtaca ccctacccac
     6181 caaagagtgt gcccaccctc tgcttgggga caggtgggtc tgtcttgttt taatccctgg
     6241 cttgccagct catgcccaaa gggaaggaca gttcatctag ttgcattaga tgtttccctg
     6301 acactgactg aggtgagaga acaaggtttt ggctcttata gagcttgtgt gaaaggcaca
     6361 tgggtcagct cttccggccg tcctttatgc tgctatggta cgtgttttgg tctctgttct
     6421 aaccacgact cacgtgtaag gttcttgtct ttctatatgg gcagttgtag ccacagacac
     6481 tcagcactcc tctagggctt taggggtggc tcttggaagt ttctttggct gtctgtggac
     6541 tgtcacttcc catgaaaagg tcacattacc aaaacactgc ctggtcttca gacttgaagc
     6601 actgtgatag gactttaaat agtcataata aaatactata tctttatggg catttcacaa
     6661 acacagtaaa attgtgacat tttatgtggc tgagaatgct cagataagta taccagatag
     6721 agccttatgg agtgtgtgtg atatttgtgt gcacacatag ccagacagac aggaagatga
     6781 aaaatgctta ttttaacata taatatggct ttagttttgg gccatttttt tttcagatac
     6841 actgtgataa ggttttttat ataaatatct ctagtcatgg gacccatttt gttttttcag
     6901 atgtgtttaa tggtagtttt attaagtgca aaaatacgga tgaattcaaa ttattcaaca
     6961 tgcctacacg gtaagtgtga cttgctaggg caagttagct ctcaagggct gagctccaag
     7021 tctaaatagc tggcccattt gtgaggaatt aacacttgac taataaccat tgtctgtctg
     7081 ttcctgagat ataaaagcac ccatacttgt taaagtacct atacttgtta gcactatcag
     7141 acagattttt catctacata tatgcagaag ttacccctta ttaaatatta ctgagtatta
     7201 agtagctatc tgtcagccac taaatttgta agatctattt aagaaaggcc attaaaccat
     7261 accgtgttga cttgtttttg taatcaaggt gactaaggaa ataatttcag ttgtgtaaat
     7321 aaaataaatc ataaaatgtg t
//
