LOCUS       NM_001085492            7458 bp    mRNA    linear   ROD 10-DEC-2024
DEFINITION  Mus musculus arginine glutamic acid dipeptide (RE) repeats (Rere),
            mRNA.
ACCESSION   NM_001085492 XM_204015 XM_907824
VERSION     NM_001085492.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 7458)
  AUTHORS   Alam,S.S., Kumar,S., Beauchamp,M.C., Bareke,E., Boucher,A.,
            Nzirorera,N., Dong,Y., Padilla,R., Zhang,S.J., Majewski,J. and
            Jerome-Majewska,L.A.
  TITLE     Snrpb is required in murine neural crest cells for proper splicing
            and craniofacial morphogenesis
  JOURNAL   Dis Model Mech 15 (6) (2022)
   PUBMED   35593225
REFERENCE   2  (bases 1 to 7458)
  AUTHORS   Kim,B.J. and Scott,D.A.
  TITLE     RERE deficiency causes retinal and optic nerve atrophy through
            degeneration of retinal cells
  JOURNAL   Dev Dyn 250 (10), 1398-1409 (2021)
   PUBMED   33742727
  REMARK    GeneRIF: RERE deficiency causes retinal and optic nerve atrophy
            through degeneration of retinal cells.
REFERENCE   3  (bases 1 to 7458)
  AUTHORS   Kim,B.J., Zaveri,H.P., Kundert,P.N., Jordan,V.K., Scott,T.M.,
            Carmichael,J. and Scott,D.A.
  TITLE     RERE deficiency contributes to the development of orofacial clefts
            in humans and mice
  JOURNAL   Hum Mol Genet 30 (7), 595-602 (2021)
   PUBMED   33772547
  REMARK    GeneRIF: RERE deficiency contributes to the development of
            orofacial clefts in humans and mice.
REFERENCE   4  (bases 1 to 7458)
  AUTHORS   Kim,B.J., Zaveri,H.P., Jordan,V.K., Hernandez-Garcia,A.,
            Jacob,D.J., Zamora,D.L., Yu,W., Schwartz,R.J. and Scott,D.A.
  TITLE     RERE deficiency leads to decreased expression of GATA4 and the
            development of ventricular septal defects
  JOURNAL   Dis Model Mech 11 (9) (2018)
   PUBMED   30061196
  REMARK    GeneRIF: Rere and Gata4 interact genetically in the development of
            congenital heart defects.
            Publication Status: Online-Only
REFERENCE   5  (bases 1 to 7458)
  AUTHORS   Vilhais-Neto,G.C., Fournier,M., Plassat,J.L., Sardiu,M.E.,
            Saraf,A., Garnier,J.M., Maruhashi,M., Florens,L., Washburn,M.P. and
            Pourquie,O.
  TITLE     The WHHERE coactivator complex is required for retinoic
            acid-dependent regulation of embryonic symmetry
  JOURNAL   Nat Commun 8 (1), 728 (2017)
   PUBMED   28959017
  REMARK    Publication Status: Online-Only
REFERENCE   6  (bases 1 to 7458)
  AUTHORS   Hou,R. and Sibinga,N.E.
  TITLE     Atrophin proteins interact with the Fat1 cadherin and regulate
            migration and orientation in vascular smooth muscle cells
  JOURNAL   J Biol Chem 284 (11), 6955-6965 (2009)
   PUBMED   19131340
REFERENCE   7  (bases 1 to 7458)
  AUTHORS   Shen,Y., Lee,G., Choe,Y., Zoltewicz,J.S. and Peterson,A.S.
  TITLE     Functional architecture of atrophins
  JOURNAL   J Biol Chem 282 (7), 5037-5044 (2007)
   PUBMED   17150957
  REMARK    GeneRIF: Atrophin-1 and the short form of Atrophin-2 can act as
            potent and evolutionarily conserved transcriptional activators.
REFERENCE   8  (bases 1 to 7458)
  AUTHORS   Zoltewicz,J.S., Stewart,N.J., Leung,R. and Peterson,A.S.
  TITLE     Atrophin 2 recruits histone deacetylase and is required for the
            function of multiple signaling centers during mouse embryogenesis
  JOURNAL   Development 131 (1), 3-14 (2004)
   PUBMED   14645126
  REMARK    GeneRIF: act as transcriptional co-repressor during embryonic
            development.
REFERENCE   9  (bases 1 to 7458)
  AUTHORS   Okazaki,N., Kikuno,R., Ohara,R., Inamoto,S., Aizawa,H., Yuasa,S.,
            Nakajima,D., Nagase,T., Ohara,O. and Koga,H.
  TITLE     Prediction of the coding sequences of mouse homologues of KIAA
            gene: II. The complete nucleotide sequences of 400 mouse
            KIAA-homologous cDNAs identified by screening of terminal sequences
            of cDNA clones randomly sampled from size-fractionated libraries
  JOURNAL   DNA Res 10 (1), 35-48 (2003)
   PUBMED   12693553
REFERENCE   10 (bases 1 to 7458)
  AUTHORS   Stryke,D., Kawamoto,M., Huang,C.C., Johns,S.J., King,L.A.,
            Harper,C.A., Meng,E.C., Lee,R.E., Yee,A., L'Italien,L.,
            Chuang,P.T., Young,S.G., Skarnes,W.C., Babbitt,P.C. and Ferrin,T.E.
  TITLE     BayGenomics: a resource of insertional mutations in mouse embryonic
            stem cells
  JOURNAL   Nucleic Acids Res 31 (1), 278-281 (2003)
   PUBMED   12520002
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL606903.8, AL691453.7, AL606988.16 and AL606982.21.
            
            On or before Jul 25, 2007 this sequence version replaced
            XM_907824.2, XM_204015.5.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMN00849374,
                              SAMN00849375 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-160               AL606903.8         103873-104032
            161-629             AL691453.7         54915-55383
            630-700             AL691453.7         80242-80312
            701-826             AL691453.7         88062-88187
            827-932             AL606988.16        24916-25021
            933-1029            AL606988.16        26516-26612
            1030-1134           AL606988.16        33585-33689
            1135-1183           AL606988.16        56224-56272
            1184-1308           AL606988.16        65051-65175
            1309-1408           AL606988.16        66160-66259
            1409-1507           AL606988.16        91068-91166
            1508-1588           AL606988.16        126437-126517
            1589-1751           AL606982.21        8975-9137
            1752-1844           AL606982.21        10108-10200
            1845-2044           AL606982.21        10668-10867
            2045-2206           AL606982.21        11846-12007
            2207-2320           AL606982.21        12261-12374
            2321-3675           AL606982.21        12598-13952
            3676-3898           AL606982.21        14062-14284
            3899-4619           AL606982.21        14880-15600
            4620-4766           AL606982.21        16527-16673
            4767-4947           AL606982.21        17146-17326
            4948-7458           AL606982.21        17577-20087
FEATURES             Location/Qualifiers
     source          1..7458
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="4"
                     /map="4 81.34 cM"
     gene            1..7458
                     /gene="Rere"
                     /gene_synonym="1110033A15Rik; ARG; ARP; ATN1L; Atr2; DNB1;
                     eye<m03Jus>; eyes3; mKIAA0458"
                     /note="arginine glutamic acid dipeptide (RE) repeats"
                     /db_xref="GeneID:68703"
                     /db_xref="MGI:MGI:2683486"
     exon            1..160
                     /gene="Rere"
                     /gene_synonym="1110033A15Rik; ARG; ARP; ATN1L; Atr2; DNB1;
                     eye<m03Jus>; eyes3; mKIAA0458"
                     /inference="alignment:Splign:2.1.0"
     exon            161..629
                     /gene="Rere"
                     /gene_synonym="1110033A15Rik; ARG; ARP; ATN1L; Atr2; DNB1;
                     eye<m03Jus>; eyes3; mKIAA0458"
                     /inference="alignment:Splign:2.1.0"
     CDS             305..4981
                     /gene="Rere"
                     /gene_synonym="1110033A15Rik; ARG; ARP; ATN1L; Atr2; DNB1;
                     eye<m03Jus>; eyes3; mKIAA0458"
                     /note="atrophin-2"
                     /codon_start=1
                     /product="arginine-glutamic acid dipeptide repeats
                     protein"
                     /protein_id="NP_001078961.1"
                     /db_xref="CCDS:CCDS38979.1"
                     /db_xref="GeneID:68703"
                     /db_xref="MGI:MGI:2683486"
                     /translation="MTADKDKDKDKEKDRDRDRDRERDKRDKARESENARPRRSCTLE
                     GGAKNYAESDHSEDEDNDNNSATTEESNKKSRKKPPKKKSRYERTDTGEITSYITEDD
                     VVYRPGDCVYIESRRPNTPYFICSIQDFKLVHSSQACCRSPAPAFCDPPACSLPVAPQ
                     PPQHLSEAGRGPGGSKRDHLLMNVKWYYRQSEVPDSVYQHLVQDRHNENDSGRELVIT
                     DPVIKNRELFISDYVDTYHAAALRGKCNISHFSDIFAAREFKARVDSFFYILGYNPET
                     RRLNSTQGEIRVGPSHQAKLPDLQPFPSPDGDTVTQHEELVWMPGVSDCDLLMYLRAA
                     RSMAAFAGMCDGGSTEDGCVAASRDDTTLNALNTLHESSYDAGKALQRLVKKPVPKLI
                     EKCWTEDEVKRFVKGLRQYGKNFFRIRKELLPSKETGELITFYYYWKKTPEAASSRAH
                     RRHRRQAVFRRIKTRTASTPVNTPSRPPSSEFLDLSSASEDDFDSEDSEQELKGYACR
                     HCFTTTSKDWHHGGRENILLCTDCRIHFKKYGELPPIEKPVDPPPFMFKPVKEEDDGL
                     SGKHSMRTRRSRGSMSTLRSGRKKQPTSPDGRASPINEDIRSSGRNSPSAASTSSNDS
                     KAETVKKSAKKVKEEAASPLKSTKRQREKVASDTEDTDRITSKKTKTQEISRPNSPSE
                     GEGESSDSRSVNDEGSSDPKDIDQDNRSTSPSIPSPQDNESDSDSSAQQQMLQAQPPA
                     LQAPSGAASAPSTAPPGTPQLPTQGPTPSATAVPPQGSPATSQPPNQTQSTVAPAAHT
                     HIQQAPTLHPPRLPSPHPPLQPMTAPPSQSSAQPHPQPSLHSQGPPGPHSLQTGPLLQ
                     HPGPPQPFGLPSQPSQGQGPLGPSPAAAHPHSTIQLPASQSALQPQQPPREQPLPPAP
                     LAMPHIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSLNANLPPPPALKPLSSLSTHHP
                     PSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQSLPPPAASHPTTGLHQVPSQSPFPQHP
                     FVPGGPPPITPPSCPPTSTPPAGPSSSSQPPCSAAVSSGGSVPGAPSCPLPAVQIKEE
                     ALDEAEEPESPPPPPRSPSPEPTVVDTPSHASQSARFYKHLDRGYNSCARTDLYFMPL
                     AGSKLAKKREEAIEKAKREAEQKAREEREREKEKEKEREREREREREAERAAKASSSA
                     HEGRLSDPQLSGPGHMRPSFEPPPTTIAAVPPYIGPDTPALRTLSEYARPHVMSPTNR
                     NHPFYMPLNPTDPLLAYHMPGLYNVDPTIRERELREREIREREIRERELRERMKPGFE
                     VKPPELDPLHPATNPMEHFARHSALTIPPAAGPHPFASFHPGLNPLERERLALAGPQL
                     RPEMSYPDRLAAERIHAERMASLTSDPLARLQMFNVTPHHHQHSHIHSHLHLHQQDPL
                     HQGSAGPVHPLVDPLTAGPHLARFPYPPGTLPNPLLGQPPHEHEMLRHPVFGTPYPRD
                     LPGAIPPPMSAAHQLQAMHAQSAELQRLAMEQQWLHGHPHMHGGHLPSQEDYYSRLKK
                     EGDKQL"
     exon            630..700
                     /gene="Rere"
                     /gene_synonym="1110033A15Rik; ARG; ARP; ATN1L; Atr2; DNB1;
                     eye<m03Jus>; eyes3; mKIAA0458"
                     /inference="alignment:Splign:2.1.0"
     exon            701..826
                     /gene="Rere"
                     /gene_synonym="1110033A15Rik; ARG; ARP; ATN1L; Atr2; DNB1;
                     eye<m03Jus>; eyes3; mKIAA0458"
                     /inference="alignment:Splign:2.1.0"
     exon            827..932
                     /gene="Rere"
                     /gene_synonym="1110033A15Rik; ARG; ARP; ATN1L; Atr2; DNB1;
                     eye<m03Jus>; eyes3; mKIAA0458"
                     /inference="alignment:Splign:2.1.0"
     exon            933..1029
                     /gene="Rere"
                     /gene_synonym="1110033A15Rik; ARG; ARP; ATN1L; Atr2; DNB1;
                     eye<m03Jus>; eyes3; mKIAA0458"
                     /inference="alignment:Splign:2.1.0"
     exon            1030..1134
                     /gene="Rere"
                     /gene_synonym="1110033A15Rik; ARG; ARP; ATN1L; Atr2; DNB1;
                     eye<m03Jus>; eyes3; mKIAA0458"
                     /inference="alignment:Splign:2.1.0"
     exon            1135..1183
                     /gene="Rere"
                     /gene_synonym="1110033A15Rik; ARG; ARP; ATN1L; Atr2; DNB1;
                     eye<m03Jus>; eyes3; mKIAA0458"
                     /inference="alignment:Splign:2.1.0"
     exon            1184..1308
                     /gene="Rere"
                     /gene_synonym="1110033A15Rik; ARG; ARP; ATN1L; Atr2; DNB1;
                     eye<m03Jus>; eyes3; mKIAA0458"
                     /inference="alignment:Splign:2.1.0"
     exon            1309..1408
                     /gene="Rere"
                     /gene_synonym="1110033A15Rik; ARG; ARP; ATN1L; Atr2; DNB1;
                     eye<m03Jus>; eyes3; mKIAA0458"
                     /inference="alignment:Splign:2.1.0"
     exon            1409..1507
                     /gene="Rere"
                     /gene_synonym="1110033A15Rik; ARG; ARP; ATN1L; Atr2; DNB1;
                     eye<m03Jus>; eyes3; mKIAA0458"
                     /inference="alignment:Splign:2.1.0"
     exon            1508..1588
                     /gene="Rere"
                     /gene_synonym="1110033A15Rik; ARG; ARP; ATN1L; Atr2; DNB1;
                     eye<m03Jus>; eyes3; mKIAA0458"
                     /inference="alignment:Splign:2.1.0"
     exon            1589..1751
                     /gene="Rere"
                     /gene_synonym="1110033A15Rik; ARG; ARP; ATN1L; Atr2; DNB1;
                     eye<m03Jus>; eyes3; mKIAA0458"
                     /inference="alignment:Splign:2.1.0"
     exon            1752..1844
                     /gene="Rere"
                     /gene_synonym="1110033A15Rik; ARG; ARP; ATN1L; Atr2; DNB1;
                     eye<m03Jus>; eyes3; mKIAA0458"
                     /inference="alignment:Splign:2.1.0"
     exon            1845..2044
                     /gene="Rere"
                     /gene_synonym="1110033A15Rik; ARG; ARP; ATN1L; Atr2; DNB1;
                     eye<m03Jus>; eyes3; mKIAA0458"
                     /inference="alignment:Splign:2.1.0"
     exon            2045..2206
                     /gene="Rere"
                     /gene_synonym="1110033A15Rik; ARG; ARP; ATN1L; Atr2; DNB1;
                     eye<m03Jus>; eyes3; mKIAA0458"
                     /inference="alignment:Splign:2.1.0"
     exon            2207..2320
                     /gene="Rere"
                     /gene_synonym="1110033A15Rik; ARG; ARP; ATN1L; Atr2; DNB1;
                     eye<m03Jus>; eyes3; mKIAA0458"
                     /inference="alignment:Splign:2.1.0"
     exon            2321..3675
                     /gene="Rere"
                     /gene_synonym="1110033A15Rik; ARG; ARP; ATN1L; Atr2; DNB1;
                     eye<m03Jus>; eyes3; mKIAA0458"
                     /inference="alignment:Splign:2.1.0"
     exon            3676..3898
                     /gene="Rere"
                     /gene_synonym="1110033A15Rik; ARG; ARP; ATN1L; Atr2; DNB1;
                     eye<m03Jus>; eyes3; mKIAA0458"
                     /inference="alignment:Splign:2.1.0"
     exon            3899..4619
                     /gene="Rere"
                     /gene_synonym="1110033A15Rik; ARG; ARP; ATN1L; Atr2; DNB1;
                     eye<m03Jus>; eyes3; mKIAA0458"
                     /inference="alignment:Splign:2.1.0"
     exon            4620..4766
                     /gene="Rere"
                     /gene_synonym="1110033A15Rik; ARG; ARP; ATN1L; Atr2; DNB1;
                     eye<m03Jus>; eyes3; mKIAA0458"
                     /inference="alignment:Splign:2.1.0"
     exon            4767..4947
                     /gene="Rere"
                     /gene_synonym="1110033A15Rik; ARG; ARP; ATN1L; Atr2; DNB1;
                     eye<m03Jus>; eyes3; mKIAA0458"
                     /inference="alignment:Splign:2.1.0"
     exon            4948..7458
                     /gene="Rere"
                     /gene_synonym="1110033A15Rik; ARG; ARP; ATN1L; Atr2; DNB1;
                     eye<m03Jus>; eyes3; mKIAA0458"
                     /inference="alignment:Splign:2.1.0"
     regulatory      7434..7439
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Rere"
                     /gene_synonym="1110033A15Rik; ARG; ARP; ATN1L; Atr2; DNB1;
                     eye<m03Jus>; eyes3; mKIAA0458"
                     /note="hexamer: AATAAA"
     polyA_site      7458
                     /gene="Rere"
                     /gene_synonym="1110033A15Rik; ARG; ARP; ATN1L; Atr2; DNB1;
                     eye<m03Jus>; eyes3; mKIAA0458"
                     /note="major polyA site"
ORIGIN      
        1 cagccccccg gtgtcgcatc cccgcgggcc ggccccttcg gccccgcgcc caccgccctc
       61 ggtccgccgc cggcccccgc ggcctccctc ccggtccctg cactttcccc ggagcccggc
      121 cgccacccct ctcattgatg gtgtagcgcc cgaggggaag aatatttgaa acgttggggt
      181 tgttggagtg gttggatttt ccctggaatt gagtgagaaa ttcagaagac tgaagcccag
      241 gctcactgtc tacctttcac ggaggcctag ccgtgagagg acagaagaag gcacgtggag
      301 aatcatgaca gctgacaaag ataaagacaa agacaaagag aaggaccggg accgggatcg
      361 ggaccgagaa agagataaaa gagacaaagc aagagagagc gagaatgcca ggcctcgcag
      421 gagctgtacc ttggagggag gagccaaaaa ctatgctgag agcgatcaca gcgaggacga
      481 agacaacgac aacaacagcg ccaccacgga ggagtccaac aagaagagca gaaagaaacc
      541 tccgaaaaaa aagtcccgct acgagaggac agacactggt gagataactt cttacatcac
      601 cgaggacgac gttgtctaca gaccgggaga ctgtgtgtat atcgagagtc ggcggccaaa
      661 cacaccgtat ttcatctgca gcatccaaga cttcaaactg gtccacagct cccaggcctg
      721 ttgcagatct ccagctcctg ctttctgtga ccccccagca tgctctctgc cggtggcacc
      781 acagccacca cagcacctct ctgaagccgg gagagggcct ggagggagta agagggacca
      841 tctactcatg aacgtcaaat ggtactaccg tcagtctgaa gtcccagatt ctgtctatca
      901 gcatttggtt caggatcggc ataatgaaaa cgactctgga agagagcttg tcatcacaga
      961 tccagtcatc aagaatcggg aactcttcat ttctgattat gttgacacct accatgctgc
     1021 tgccctaaga gggaagtgta acatctccca tttttctgac atatttgctg ctcgagagtt
     1081 taaagcccga gtggactcat ttttctacat attaggatac aaccctgaga caaggcggct
     1141 gaatagtacc caaggggaaa ttcgagttgg ccctagccac caggccaaac ttccagatct
     1201 gcaaccattt ccttctccag atggtgatac tgtgactcag catgaggaac ttgtctggat
     1261 gcctggagtc agtgactgtg acctcctcat gtacttgagg gcagcaagga gcatggcagc
     1321 atttgcaggg atgtgtgatg gaggctccac agaggatggc tgtgttgcag catctcggga
     1381 tgacaccact ctcaatgcac tgaacacact acatgaaagc agttatgatg ccggcaaagc
     1441 cctgcagcgc ctggtgaaga agcctgtgcc caagctgatc gagaagtgct ggacagagga
     1501 tgaagtgaaa cgcttcgtta aggggctccg acaatacggc aagaacttct tcagaatcag
     1561 aaaggagctg cttcccagta aggaaaccgg ggaactgatt accttctatt actactggaa
     1621 gaaaacacca gaggcggcca gctcccgtgc ccaccgccgc caccgcaggc aggcggtgtt
     1681 cagaagaatt aagactcgca cagcgtccac ccctgtcaac acgccctcca gaccaccttc
     1741 cagtgaattc ttggacctga gttcagctag tgaggatgac tttgacagtg aggacagcga
     1801 acaggagctg aaggggtacg cctgccgtca ctgcttcacc accacctcca aagactggca
     1861 ccacgggggc cgggaaaaca tcctactgtg cacggactgt cgcatccact tcaagaagta
     1921 cggtgagctg ccacccatcg agaagcccgt ggaccccccg cccttcatgt tcaagcctgt
     1981 caaggaggag gacgatgggc tcagtgggaa gcatagcatg aggacgcggc ggagccgggg
     2041 ctcgatgtct acactacgca gtggtcggaa gaagcagccc accagtcctg atggtcgtgc
     2101 ctcacccatc aatgaagaca tccgatccag tggccggaac tcccccagtg ctgctagcac
     2161 ttccagcaat gacagtaaag cagagacagt gaagaagtca gccaagaagg tgaaggaaga
     2221 ggctgcatcc cctctgaaga gcaccaagcg ccagcgggag aaggtggcct ctgacacaga
     2281 agacactgat aggatcacct ccaaaaagac aaagacccag gagattagcc gtcccaactc
     2341 tccctctgaa ggagaggggg agagttcgga cagtcgcagt gtcaacgatg agggcagcag
     2401 tgacccgaaa gacattgacc aggataatcg cagcacgtct cccagtatcc ccagccctca
     2461 ggataatgag agtgactcgg actcatcagc acagcagcag atgttgcagg cccagccccc
     2521 agccttgcaa gctcccagtg gtgctgcctc ggctccctcc acagcccctc caggaacacc
     2581 ccagcttccc acccaaggac ccacaccctc tgccactgca gtccctccac agggctcccc
     2641 tgcaacctca cagcccccta accagactca gtctacagtt gcacctgcag cccacaccca
     2701 catccaacag gcacccaccc tgcacccccc tcggctgccc tcacctcatc ctccactgca
     2761 gcctatgact gcaccgccta gccagagctc tgcacaacct cacccccagc cctccttgca
     2821 cagtcagggc ccgcctggcc ctcacagcct acagactgga cccctgttac agcacccagg
     2881 acctcctcag ccctttggac ttccttccca gccctcccaa ggtcagggcc ctctgggccc
     2941 ctccccggca gcagctcatc ctcatagcac catacagctt ccagcgtcgc agtcagcgct
     3001 gcagccccaa cagcccccaa gggaacagcc cttgcctcct gcccctttag ctatgcctca
     3061 catcaaaccc ccacccacca caccaattcc ccagcttcca gcaccacaag cccacaaaca
     3121 tccgcctcac ctctcaggcc cctccccctt ctctctgaat gccaatctgc cacccccgcc
     3181 agccctgaaa cccctgagct cactgtccac acaccaccct ccctcagccc accctccacc
     3241 cttacaactc atgcctcaga gccagccctt gccctcttca cctgcccagc cacctgggct
     3301 gacccagagc cagagcctac cacctcctgc tgcctcccat cctaccactg gcctccacca
     3361 ggtgccctcc caatccccat ttccccagca ccctttcgta cctggaggcc cccctcccat
     3421 caccccgccc tcctgccccc ccacttccac ccctcctgcc gggcccagct cctcatcaca
     3481 gccaccctgc tctgctgctg tgtcttctgg aggcagtgtt cctggggcgc catcttgccc
     3541 actccctgct gtgcaaatca aggaggaggc tctggatgaa gctgaggagc cagagagccc
     3601 tcctccaccc cccaggagcc catcccctga gcccactgta gtggacaccc ccagccatgc
     3661 cagccagtct gccaggttct acaaacacct ggaccggggc tacaactcgt gtgcacggac
     3721 agacctgtac ttcatgcctc tggctggatc caaactagcc aagaagaggg aggaggccat
     3781 tgagaaggcc aagcgggagg ctgaacagaa agcccgagag gaacgggagc gggagaaaga
     3841 gaaggaaaaa gagcgagaac gggagagaga gcgggaacgg gaggcagagc gcgctgctaa
     3901 ggcatccagc tctgcacatg aaggccgtct tagtgaccct cagctcagtg gcccgggtca
     3961 catgcgaccc tccttcgagc caccaccgac cacaatcgct gctgtgcccc catatattgg
     4021 gcctgacaca cctgccctcc ggacactgag cgaatatgct cggcctcatg tcatgtctcc
     4081 caccaaccgc aaccacccct tctacatgcc ccttaatccc accgaccccc tgctggccta
     4141 ccacatgcct ggcttgtaca atgttgatcc caccatccgc gagcgggagc tccgagagcg
     4201 cgagatcaga gagcgcgaga tccgggagcg ggaattgcgg gagaggatga agccaggctt
     4261 tgaggtgaag cccccagagc tggaccccct gcacccagcc accaacccca tggagcattt
     4321 tgcccggcac agcgccctca ccatccctcc tgcagctggc ccccacccct ttgcctcttt
     4381 ccacccgggc ctcaaccctt tggagcggga gagactggca ctagcaggtc ctcagctgcg
     4441 gcctgagatg agttacccag acagactggc agccgagcgc atccatgctg agcgtatggc
     4501 atcactcacc agcgaccccc tggcacgact gcagatgttt aatgtcactc cacaccatca
     4561 ccagcattca cacatccact cccacctcca cctccaccag caggatcctc tccaccaagg
     4621 ttcagcaggc ccagttcacc ccctggttga ccccttgact gctggccctc acttagctcg
     4681 cttcccctat cccccgggca ccctccctaa ccctctactt ggacagcccc ctcacgagca
     4741 cgagatgctg cgccacccag tttttggcac cccctatccc cgagacctgc ctggggctat
     4801 tccacccccc atgtcagcag cccaccagct tcaggccatg catgcccagt cagccgagct
     4861 acagagacta gccatggagc agcagtggct gcacggacat ccacacatgc atggtggcca
     4921 tctgccaagt caggaggatt attacagtcg actgaagaaa gaaggtgaca agcagttata
     4981 agttatttat ttgttaatgc tggctgtgga aaccccagtt ctagggggca gaaacaggac
     5041 atttacatct agtaggggct gcaagagcaa agaggaatat cgtctaaaga tttctctata
     5101 tatttaaaac ccacaactaa aacacatctg cataatagtg tttgtttgtt gagaggattt
     5161 cctgagactg gtttgggtct ccctgcatga cagtccccca gaaacttggt gtgtcctggg
     5221 ctggactgac acccagaaag cttacctgcg agcttggggt ttggcttgag ttctcttttc
     5281 cttgatttct cagtaggtgc tagagtccgt tcacaccctt cactgtgcgc gcagacactg
     5341 aggcacgtgg gctctggaac ccgcagggtt tgcagagagg cggcatatga gtttgaaatc
     5401 caagagctat aatttttaaa aaatctttta ttttaataca ttgtaggaaa tcttcataat
     5461 ttgagacagt tctgcagcat ggctttttac atctgtaaat aaataatttt agaagtcttt
     5521 ttttctttcc acagacgact attctgatct attttttcca gccatgtcac aaagtgtgaa
     5581 ttcctaccag ctattgacag agtacagagt tgatttttta ataaaaagtt atatataatt
     5641 atccctttaa ttaaagggaa cagatgggcg tttctagttt taagcaggca ggagcttggg
     5701 actaggtttg gtcacagcag cgagcatcca agggttggca gggacagtgt tacaggctct
     5761 ttattttgct gctttgattt tgcttctgtc tgcccctcac atgtgcagtg gcaggcgtgt
     5821 ttgagcgagc ctccttcctt attcataggg attcagtgtt gactgttccc tggtgtcccc
     5881 gctgtcctgt gtcgtctggt atagaaagcg catgtttctg tatcggtgtc tgatgataag
     5941 tttccttgga gttttatgca catgtttgat tgttctagat aaattgtcat aaacattcta
     6001 ggaagttcaa gaaaatgatg cagtacccag cacatgaaag acctacaaca tgtgcttgcc
     6061 aaaggaatgt tagaatctgc tcatgtgtgt gtcaccatgc caagccatgc cagccacaga
     6121 ctgaggcttc cgggtgagga acaccctggg gctactatgt ttgtaggtct catgtgctca
     6181 gggctatgaa gtaggctgtg caggtgacag caccctgcta ggaagctgtg tgtgtcctgc
     6241 ctttcctcct ggaatatgta cggatggaag tcttggttga agcaggttcc cctgggaagt
     6301 gctctcagca ggccttgcgg agcagagcag agctgggcag agctgactcc tgccccgctg
     6361 tccctgatgg aaccttcctt ccagagctgt ggaagagatg tttgtgaccc ctcccttgga
     6421 ctcttggggg ccaatcccac tcttgagtgc aatggttgca tttagaatca gctagctagc
     6481 caggggccat cctgtgggtc agtagatgag gtgtgtcctg gccctgcgga gagaagaggc
     6541 ctgtggttca gctggcacgc tctgctccag gctctgactc aggggtggct gagcctcatg
     6601 ctcccagaac catgcatggg gcagctagga tccatttgtc tgttggaaat gtttgtagct
     6661 tttttgtttt gttttttaac tttctttttc tcattccatt tctgccttaa ctttggttct
     6721 tcataggagg caagctcaaa ttaacctttt gccatcaaac cttgtagccg tcttggcatg
     6781 aaggcatgtt ttccttctgg gggtggtgac atgccctcca gacggcctgc catccagccc
     6841 tctggcctga ggaagacccc cataggctcc ggacaggcag gtcctttcta tcccatgcca
     6901 ccacttcctt ccccctttaa ctgagtctgc tgttcagtta agcctttatt tcctctccag
     6961 tacccatttc caaagagaaa gagtgaagta ctttgaagtc tgtacttgaa atctgtctgg
     7021 aagtgtttcc ttgttagttt tgggtttctc ccctgtccca aggctcagag tcttcatctc
     7081 ctacgtgact gactacagtt ggtttggagg ccctggacct ctgtggcgtc tttgaagcct
     7141 ggcctcttgg cttccttttg gactttgctt gctttcattt gaagtttggg tttgctttct
     7201 gtgttctgtg cgtatcttgt tcagtgtcgt caaggttggg cttcacgtct cactgcagtg
     7261 gagcgagcgg acattctgat cgctgcattt ctttagatct cggagctaag tgtatatatg
     7321 agtagtttgc caatggataa cacagtgtaa acagtagaca cccagaaaat cgtgacttct
     7381 gtgttctctc catttgagta ttttgtaatt tttttgaaat atttgtggac ataaataaaa
     7441 ccaagctaca ctacagca
//
