LOCUS       NM_009048               2991 bp    mRNA    linear   ROD 14-JUN-2024
DEFINITION  Mus musculus RalBP1 associated Eps domain containing protein
            (Reps1), transcript variant 1, mRNA.
ACCESSION   NM_009048
VERSION     NM_009048.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2991)
  AUTHORS   Stryke,D., Kawamoto,M., Huang,C.C., Johns,S.J., King,L.A.,
            Harper,C.A., Meng,E.C., Lee,R.E., Yee,A., L'Italien,L.,
            Chuang,P.T., Young,S.G., Skarnes,W.C., Babbitt,P.C. and Ferrin,T.E.
  TITLE     BayGenomics: a resource of insertional mutations in mouse embryonic
            stem cells
  JOURNAL   Nucleic Acids Res 31 (1), 278-281 (2003)
   PUBMED   12520002
REFERENCE   2  (bases 1 to 2991)
  AUTHORS   Xu,J., Zhou,Z., Zeng,L., Huang,Y., Zhao,W., Cheng,C., Xu,M., Xie,Y.
            and Mao,Y.
  TITLE     Cloning, expression and characterization of a novel human REPS1
            gene
  JOURNAL   Biochim Biophys Acta 1522 (2), 118-121 (2001)
   PUBMED   11750063
REFERENCE   3  (bases 1 to 2991)
  AUTHORS   Kim,S., Cullis,D.N., Feig,L.A. and Baleja,J.D.
  TITLE     Solution structure of the Reps1 EH domain and characterization of
            its binding to NPF target sequences
  JOURNAL   Biochemistry 40 (23), 6776-6785 (2001)
   PUBMED   11389591
REFERENCE   4  (bases 1 to 2991)
  AUTHORS   Yamaguchi,A., Urano,T., Goi,T. and Feig,L.A.
  TITLE     An Eps homology (EH) domain protein that binds to the Ral-GTPase
            target, RalBP1
  JOURNAL   J Biol Chem 272 (50), 31230-31234 (1997)
   PUBMED   9395447
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC153433.6.
            
            On Dec 30, 2022 this sequence version replaced NM_009048.2.
            
            Transcript Variant: This variant (1) represents the longest
            transcript and encodes the longest isoform (1).
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK150284.1, AK151309.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-560               AC153433.6         105402-105961       c
            561-684             AC153433.6         71946-72069         c
            685-881             AC153433.6         68476-68672         c
            882-1035            AC153433.6         68194-68347         c
            1036-1160           AC153433.6         67614-67738         c
            1161-1323           AC153433.6         66945-67107         c
            1324-1387           AC153433.6         66609-66672         c
            1388-1542           AC153433.6         65181-65335         c
            1543-1664           AC153433.6         57242-57363         c
            1665-1745           AC153433.6         53769-53849         c
            1746-1833           AC153433.6         47031-47118         c
            1834-1935           AC153433.6         45700-45801         c
            1936-2005           AC153433.6         43783-43852         c
            2006-2124           AC153433.6         42472-42590         c
            2125-2189           AC153433.6         41288-41352         c
            2190-2375           AC153433.6         40299-40484         c
            2376-2471           AC153433.6         38987-39082         c
            2472-2620           AC153433.6         38344-38492         c
            2621-2726           AC153433.6         37813-37918         c
            2727-2991           AC153433.6         36373-36637         c
FEATURES             Location/Qualifiers
     source          1..2991
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="10"
                     /map="10 7.42 cM"
     gene            1..2991
                     /gene="Reps1"
                     /note="RalBP1 associated Eps domain containing protein"
                     /db_xref="GeneID:19707"
                     /db_xref="MGI:MGI:1196373"
     exon            1..560
                     /gene="Reps1"
                     /inference="alignment:Splign:2.1.0"
     CDS             408..2795
                     /gene="Reps1"
                     /note="isoform 1 is encoded by transcript variant 1;
                     RalBP1 associated Eps domain containing 1;
                     ralBP1-associated Eps domain-containing protein 1;
                     ralBP1-interacting protein 1"
                     /codon_start=1
                     /product="ralBP1-associated Eps domain-containing protein
                     1 isoform 1"
                     /protein_id="NP_033074.2"
                     /db_xref="CCDS:CCDS23710.2"
                     /db_xref="GeneID:19707"
                     /db_xref="MGI:MGI:1196373"
                     /translation="MEGLTLSDAEQKYYSDLFSYCDIESTKKVVVNGRVLELFRAAQL
                     PNDVVLQIMELCGATRLGYFGRSQFYIALKLVAVAQSGFPLRVESINTVKDLPLPRFV
                     ASKNEQESRLAASYSSDSENQGSYSGVIPPPPGRGQVKKGPGSHDAVQPRPSAEQQEP
                     VSPVVSPQQSPPTSPHTWRKHSRHPSGGNSERPLTGPGPFWSPFGDAQAGSSAGDAVW
                     SGQSPPPPQDNWVSFADTPPTSALLTMHPASVQDQTTVRTVASAATANEIRRQSSSYE
                     DPWKITDEQRQYYVNQFKTIQPDLNGFIPGSAAKEFFTKSKLPILELSHIWELSDFDK
                     DGALTLDEFCAAFHLVVARKNGYDLPEKLPESLMPKLIDLEDSADVGEQPGEVGYSGS
                     PAEAPPSKSPSMPSLNQTWPELNQSSEQWETFSERSSSSQTLTQFDSNIAPADPDTAI
                     VHPVPIRMTPSKIHMQEMELKRTSSDHTNPTSPLLVKPSDLSEENKINSSVKFPSGNT
                     VDGYSSSDSFPSDPEQIGSSVTRQRSHSGTSPDNTAPPPPPPRPQPSHSRSSSLDMNR
                     TFAVTTGQQQAGVVAHPPAVPPRPQPSQAPGPSVHRPVDADGLITHTSTSPQQIPEQP
                     NFADFSQFEVFAASNVSEEQDSEAEKHPEVLPAEKASDPSSSLRAAQADSKAEEKTAT
                     NVPANVSKGTTPLAPPPKPVRRRLKSEDELRPDVDEHTQKTGVLAAVLTSQPSIPRSV
                     GKDKKAIQASIRRNKETNTVLARLNSELQQQLKDVLEERISLEVQLEQLRPFSHL"
     exon            561..684
                     /gene="Reps1"
                     /inference="alignment:Splign:2.1.0"
     exon            685..881
                     /gene="Reps1"
                     /inference="alignment:Splign:2.1.0"
     exon            882..1035
                     /gene="Reps1"
                     /inference="alignment:Splign:2.1.0"
     exon            1036..1160
                     /gene="Reps1"
                     /inference="alignment:Splign:2.1.0"
     exon            1161..1323
                     /gene="Reps1"
                     /inference="alignment:Splign:2.1.0"
     exon            1324..1387
                     /gene="Reps1"
                     /inference="alignment:Splign:2.1.0"
     exon            1388..1542
                     /gene="Reps1"
                     /inference="alignment:Splign:2.1.0"
     exon            1543..1664
                     /gene="Reps1"
                     /inference="alignment:Splign:2.1.0"
     exon            1665..1745
                     /gene="Reps1"
                     /inference="alignment:Splign:2.1.0"
     exon            1746..1833
                     /gene="Reps1"
                     /inference="alignment:Splign:2.1.0"
     exon            1834..1935
                     /gene="Reps1"
                     /inference="alignment:Splign:2.1.0"
     exon            1936..2005
                     /gene="Reps1"
                     /inference="alignment:Splign:2.1.0"
     exon            2006..2124
                     /gene="Reps1"
                     /inference="alignment:Splign:2.1.0"
     exon            2125..2189
                     /gene="Reps1"
                     /inference="alignment:Splign:2.1.0"
     exon            2190..2375
                     /gene="Reps1"
                     /inference="alignment:Splign:2.1.0"
     exon            2376..2471
                     /gene="Reps1"
                     /inference="alignment:Splign:2.1.0"
     exon            2472..2620
                     /gene="Reps1"
                     /inference="alignment:Splign:2.1.0"
     exon            2621..2726
                     /gene="Reps1"
                     /inference="alignment:Splign:2.1.0"
     exon            2727..2991
                     /gene="Reps1"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2962..2967
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Reps1"
                     /note="hexamer: AATAAA"
     polyA_site      2991
                     /gene="Reps1"
                     /note="major polyA site"
ORIGIN      
        1 acatccgggt ctggagcgcg gccgccgctg tcagtgccgg gccggggcgc agtcaatggc
       61 ggccgaggga ggcggagcgg cggccacgcg cagccccgag cccccgaaac tttagacttc
      121 ggaagcccca caacttctcg gaggggggcg cgtgggcgga aggggaagcc gaggcgggaa
      181 gcccgaggga cgcggccgag cccggagccg ccgcctcctt ttccccacgc cgagcttgcg
      241 gccgcgcaca gccgcgcgcc accgccgccg gctgccccgg gccacacgag ctcgcggccc
      301 cgcggggagg ccgtgccgtg cgcagtaccc cgccggccgc cccgggtcgc ggggccggcg
      361 cccgggtggt gcatgcgggg cggggcggcc gccgggccga ggcgaagatg gaaggcttga
      421 cgctgagcga cgccgagcag aaatactact cggatctctt ctcctactgc gacatcgaga
      481 gcaccaagaa ggtggtggtc aacgggcgag tgctcgagct gttccgggcc gcgcagctgc
      541 ccaacgacgt ggtcctccag atcatggagc tttgtggtgc aacaagactt ggttattttg
      601 gaagaagtca gttctacatt gctttgaagc ttgtagctgt tgcccagtct ggttttccat
      661 taagagtgga aagtataaac actgtaaagg atctccctct cccacgattt gttgcttcaa
      721 agaatgaaca ggaatctcgc cttgcagcct cctattcttc agattctgaa aaccagggct
      781 cttactcggg tgtgatcccc cctcctcccg gcagaggcca agtcaagaag gggcctggaa
      841 gccatgacgc ggttcagcct cgtccgtctg cagagcagca ggaacctgtg tctccagtag
      901 tttcacccca gcagtcccca ccaacttctc cccacacatg gaggaagcac agccgccatc
      961 ccagtggggg gaatagtgag agacctctta caggaccggg gccattctgg tctccttttg
     1021 gtgatgcaca agcaggctcc tctgctggtg atgcggtgtg gtctggacag tccccgcctc
     1081 cacctcaaga caactgggtc agttttgcag atactccacc aaccagtgct cttttaacca
     1141 tgcatcctgc ttctgtccag gaccagacga cagtacggac tgtagcctca gctgcaactg
     1201 ccaatgagat ccgtaggcaa tccagtagtt atgaggatcc ctggaagata acagatgagc
     1261 agagacagta ttatgtaaat cagtttaaga ccattcagcc tgacctaaac ggatttatcc
     1321 caggatctgc agctaaagag ttttttacaa aatcaaaact tcctattctt gaactttctc
     1381 atatctggga actctcagac tttgataaag atggcgcatt gacactggat gagttttgtg
     1441 ctgcttttca tctggtagtt gctagaaaaa atggctatga cctaccagag aaactccctg
     1501 aaagcctgat gcccaagctg atagacttgg aagattcggc agatgtgggg gagcagccag
     1561 gtgaggtagg ttactcaggc tctcctgcag aagcacctcc aagcaagtca ccgtcgatgc
     1621 cgtccctgaa ccagacatgg ccagagctga atcagagcag tgagcagtgg gagacattta
     1681 gtgaacgctc ttcaagctca caaactctga cccaatttga ttctaacatt gcaccagctg
     1741 atcctgatac cgctattgtg catccagtcc ccatccgcat gactccaagc aaaatccaca
     1801 tgcaggaaat ggagctgaag agaacaagca gcgatcacac taatcccacc agcccgttgc
     1861 ttgtgaaacc atctgacctt tcagaagaaa ataaaatcaa ttcatcagta aaatttcctt
     1921 ctggaaatac cgtagatggg tacagtagct cagactcttt cccctctgac ccggagcaga
     1981 ttgggagcag tgtaactcgt caaaggtctc attcaggaac gtcacctgat aacactgcgc
     2041 caccacctcc ccctcccagg ccacagcctt ctcattctag atcatcatct ttagatatga
     2101 atcggacctt tgcagttacc acaggacaac aacaggctgg agttgttgcc catcctcctg
     2161 cagtgcctcc aagacctcag ccctcacagg cacccggtcc ttctgtccat cgcccagtgg
     2221 atgcagatgg tctaataact cacactagta cctcacctca gcagatacca gaacaaccaa
     2281 attttgcaga tttcagccaa tttgaagtat ttgctgcatc aaatgtctcc gaagaacaag
     2341 acagtgaagc tgagaaacat cctgaggtct tgccagctga gaaagcttct gacccctcaa
     2401 gctctcttcg ggctgcccaa gcggacagta aagctgaaga aaagacagct actaatgttc
     2461 ctgccaatgt gagcaaaggc acaacacctc tggctccacc accaaaacct gttagaagaa
     2521 gattaaagtc agaagatgag ttacggccag atgtggatga gcatacgcag aagacaggcg
     2581 tcctagctgc tgttctaaca tcacagcctt ctattcccag atctgtgggg aaagataaaa
     2641 aggctatcca ggcatccatt agacgaaata aggaaaccaa cacggttctg gccaggctga
     2701 acagtgaatt gcaacagcaa ttaaaggatg ttctggagga gagaatctcc ctggaagttc
     2761 aactggagca gctccgaccg ttttctcacc tctgagccat cgccgtgaac tgtgaacgtg
     2821 cccattctta agcagttcag ggttagagcc tatttggaaa cccagacatt cagctcactg
     2881 cttaactgaa cataaatttt atgatttgtt ttaccctata tgttcaccat tgtatttaag
     2941 tatcttttat tttttaattt caataaaagg gtcaggagga ctttctctgg a
//
