LOCUS       NM_178606               5473 bp    mRNA    linear   ROD 06-FEB-2024
DEFINITION  Mus musculus receptor accessory protein 3 (Reep3), transcript
            variant 2, mRNA.
ACCESSION   NM_178606
VERSION     NM_178606.5
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 5473)
  AUTHORS   Kurogi,S., Sekimoto,T., Funamoto,T., Ota,T., Nakamura,S., Nagai,T.,
            Nakahara,M., Yoshinobu,K., Araki,K., Araki,M. and Chosa,E.
  TITLE     Development of an efficient screening system to identify novel bone
            metabolism-related genes using the exchangeable gene trap
            mutagenesis mouse models
  JOURNAL   Sci Rep 7, 40692 (2017)
   PUBMED   28106071
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5473)
  AUTHORS   Tomas-Roca,L., Perez-Aytes,A., Puelles,L. and Marin,F.
  TITLE     In silico identification of new candidate genes for hereditary
            congenital facial paresis
  JOURNAL   Int J Dev Neurosci 29 (4), 451-460 (2011)
   PUBMED   21345367
REFERENCE   3  (bases 1 to 5473)
  AUTHORS   Saito,H., Kubota,M., Roberts,R.W., Chi,Q. and Matsunami,H.
  TITLE     RTP family members induce functional expression of mammalian
            odorant receptors
  JOURNAL   Cell 119 (5), 679-691 (2004)
   PUBMED   15550249
REFERENCE   4  (bases 1 to 5473)
  AUTHORS   Welch,C.L., Xia,Y.R., Shechter,I., Farese,R., Mehrabian,M.,
            Mehdizadeh,S., Warden,C.H. and Lusis,A.J.
  TITLE     Genetic regulation of cholesterol homeostasis: chromosomal
            organization of candidate genes
  JOURNAL   J Lipid Res 37 (7), 1406-1421 (1996)
   PUBMED   8827514
  REMARK    Erratum:[J Lipid Res 1996 Oct;37(10):2269]
REFERENCE   5  (bases 1 to 5473)
  AUTHORS   Warden,C.H., Mehrabian,M., He,K.Y., Yoon,M.Y., Diep,A., Xia,Y.R.,
            Wen,P.Z., Svenson,K.L., Sparkes,R.S. and Lusis,A.J.
  TITLE     Linkage mapping of 40 randomly isolated liver cDNA clones in the
            mouse
  JOURNAL   Genomics 18 (2), 295-307 (1993)
   PUBMED   8288233
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            CJ163373.1, AY562231.1 and AC153382.1.
            
            [WARNING] On Apr 1, 2024 this sequence was replaced by NM_178606.6.
            
            On Mar 16, 2011 this sequence version replaced NM_178606.4.
            
            Transcript Variant: This variant (2) lacks an exon in the 3' coding
            region, which results in a frameshift, compared to variant 1. The
            encoded isoform (2) is shorter and has a distinct C-terminus,
            compared to isoform 1.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK079649.1, AK005026.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164141 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-167               CJ163373.1         3-169
            168-932             AY562231.1         1-765
            933-5473            AC153382.1         49569-54109
FEATURES             Location/Qualifiers
     source          1..5473
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10090"
                     /chromosome="10"
                     /map="10 34.83 cM"
     gene            1..5473
                     /gene="Reep3"
                     /gene_synonym="D10Ucla1"
                     /note="receptor accessory protein 3"
                     /db_xref="GeneID:28193"
                     /db_xref="MGI:MGI:88930"
     exon            1..199
                     /gene="Reep3"
                     /gene_synonym="D10Ucla1"
                     /inference="alignment:Splign:2.1.0"
     CDS             168..932
                     /gene="Reep3"
                     /gene_synonym="D10Ucla1"
                     /note="isoform 2 is encoded by transcript variant 2;
                     receptor expression-enhancing protein 3"
                     /codon_start=1
                     /product="receptor expression-enhancing protein 3 isoform
                     2"
                     /protein_id="NP_848721.1"
                     /db_xref="CCDS:CCDS35926.1"
                     /db_xref="GeneID:28193"
                     /db_xref="MGI:MGI:88930"
                     /translation="MVSWMISRAVVLVFGMLYPAYYSYKAVKTKNVKEYVRWMMYWIV
                     FALYTVIETVADQTLAWFPLYYELKIAFVIWLLSPYTRGASLIYRKFLHPLLSSKERE
                     IDDYIVQAKERGYETMVNFGRQGLNLAAAAAVTAAVKSQGAITERLRSFSMHDLTAIQ
                     GDEPVGHRPYQTLPEAKRKGKQATESPAYGIPLKDGSEQTDEEAEGPFSDDEMVTHKA
                     LRRSQSMKSVKTIKGRKEVRYGSLKYKVKKRPQVYF"
     exon            200..272
                     /gene="Reep3"
                     /gene_synonym="D10Ucla1"
                     /inference="alignment:Splign:2.1.0"
     exon            273..349
                     /gene="Reep3"
                     /gene_synonym="D10Ucla1"
                     /inference="alignment:Splign:2.1.0"
     exon            350..470
                     /gene="Reep3"
                     /gene_synonym="D10Ucla1"
                     /inference="alignment:Splign:2.1.0"
     exon            471..584
                     /gene="Reep3"
                     /gene_synonym="D10Ucla1"
                     /inference="alignment:Splign:2.1.0"
     exon            585..729
                     /gene="Reep3"
                     /gene_synonym="D10Ucla1"
                     /inference="alignment:Splign:2.1.0"
     exon            730..875
                     /gene="Reep3"
                     /gene_synonym="D10Ucla1"
                     /inference="alignment:Splign:2.1.0"
     exon            876..5473
                     /gene="Reep3"
                     /gene_synonym="D10Ucla1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gggccggcgg ggccgcgggc gggggcggac gggcggggga ccgggctccg ggcggctccg
       61 ggcaccgcgc gcacacaccg ggccggctcc cgagggcgcc agcgcggccc cggggagcgc
      121 gagcggggag cgcgcggcct gcggtcagcg gcccatcggc cgaaaagatg gtgtcctgga
      181 tgatctcccg agccgtggtg ctggtgtttg gaatgctcta tccagcgtac tattcctaca
      241 aagccgtgaa gacgaaaaac gtcaaggaat acgttcgctg gatgatgtat tggatcgtct
      301 ttgccctcta cactgtcatt gaaacggtgg ccgatcagac acttgcatgg tttcccctgt
      361 actatgagct gaagattgcc ttcgtcattt ggctgctgtc gccctacact agaggggcga
      421 gtttaatcta tagaaagttc cttcatcccc tgctgtcatc aaaggaaagg gaaattgatg
      481 attatattgt ccaagccaaa gaaagaggct atgagacaat ggtgaatttt ggacggcaag
      541 gtttgaattt agcagctgca gccgccgtca ctgcagcagt gaagagccaa ggagcaataa
      601 cggagcgtct gcgaagtttc agcatgcatg atctgacagc tatccaaggg gatgagcccg
      661 tgggacacag accctaccag actttgccag aagcaaagag gaaaggcaaa caagccaccg
      721 agtcaccagc ctatggaatt ccactgaaag atggaagtga gcagacagac gaagaagcgg
      781 aggggccatt ctccgatgac gagatggtga ctcacaaggc gctgaggcga tcccagagca
      841 tgaaatctgt caagaccatc aaaggccgca aagaggtgcg gtatggctca ctaaaatata
      901 aagtgaagaa gagaccgcaa gtgtattttt agtgtctaca ccttgccctt cccaagatga
      961 ataaaccgct aacagatcaa cttcattttc taacctgatg tattcagggc ttaacacttt
     1021 aaatcttcag agtgtggcag ggatgggatt tacgcaatga ctttaaatgg tctgtgtttc
     1081 tttaacaatt acttttagat gtttaactgc taaacttagt tatgtaaggt ttgtaaatgt
     1141 acgtgtagat aacaaaagtg accgagaatc gcgtccctga tgtcagcagc aacactgagt
     1201 gcctagggcc taaggataaa gcctagctag acccagggca gacttcaaaa gtctctgctc
     1261 caggacacac ctgcctgccg ttctggtgtt gcattctgtt tacatcatct tgcctgcatc
     1321 tatcacagga gagtggtgac agcccctgag gagccagtgt cattgccata ggagggggct
     1381 gtgtccttcc ttaagcctta gacgctgaaa gttttttaaa caaatgattt gaaaaccagg
     1441 tgtccacata gcactttcct ggctagtttt gcacacttga aaattgttta cttattttac
     1501 aactgtacat ttacattttc ctgatgctgt ctgttttgtt gtctgtcata ttccgacatg
     1561 tcaagatcat gccttgaaac cgcgtcatct ccttttccta tgggtttgtt tcgtttggta
     1621 aatccattca gcccattata gacacataac tgttaagttt gtagtctttt gttttgtttt
     1681 attgaggtag ggtctcttcc ctgatcctcg tcctgcttcc acttcgccat tgctgggata
     1741 acagacgtta tcacacttgg ctcattttaa atgcccttca gttatattcc ggacatctga
     1801 gaagttatct taaacattaa ccagtttcca tcattgaatt tgatgtggtt tttctcaaca
     1861 gcaaattatt ctaggttatt ctaggttaaa aaaaaaaaag cttttggggg ctggagaggt
     1921 ggctcagagg taaagagcac tggctgctct tccagaggtc ctgagttcaa atcccatcac
     1981 ccacgtggca gctcacaact gtctgcaatc cagctccaag tgatttgaca ccctcacaca
     2041 gatatgcgta caggcaaaac accaatgcac attagataga gatagataga tagatagata
     2101 gatagataga tagatagata gatagataga tattagatag atagatagat agatagatag
     2161 atagatagat agatagatag atagattgat tttgtggaag cgtcacagac caatgtagca
     2221 cttagtgttt tctaactcat ggacttccca atgcccacac tcagctcctg agctcggcag
     2281 aggcctatgc tgccttacag acccagcaat gactaacatc ttttagatct ttttctgcct
     2341 gagattattc tctgaaaatg agtgtcaggg taaaacacaa acaccattga tgctacgtaa
     2401 caggcttcca gaaaaatgcc atcttttatt ttattttatt ttattttatt tttgggtttt
     2461 tttttttcga gacagggttt ctctgtatag ccctggctct cctggaactc actctggaga
     2521 ccaggctaaa ggccttcttt ttaatctaac agatttagag ggattgaact cagctccttt
     2581 taggttgccc tactaactgg acattgtgga cactaaatca tattggggtg atgaataatc
     2641 aaattttcaa tatcaaacaa tgcttacatg ggggtgcctg aatggcccac acacacaatg
     2701 acctcttgat actacgaata ttttctacac agaatcacat tgttaatatt tttaacacga
     2761 aataaaaatt caatcttttt cctccccaat ttaatcttgt atctccatct actttgcttt
     2821 gactaatagc ctcttccttt cgaaaaggat tctttaattt ctattcaaac atctataaag
     2881 tcccacaata aattattgga caggatgtat tcatttctca tgaaccagac ctgctctgaa
     2941 ccaatgctgt gcggcatggg tggttttccc tgcagaggcc gtgttacctg ataaggtgat
     3001 gtgataagta cagtaagtta ctttgtctcc atggggacaa attggcaaga ttgtatcata
     3061 ttcaagtcca gtatcagtat taaacttacc cttaggagct aaggatagac accatgcttg
     3121 aggtacacaa ggccttgagt tcaatcccaa aaccaaaaaa aaaaaaaaaa aagatagtta
     3181 aaacaaactt attattattt aatgagtttg tatactattt gtttcttctt ttgacttttg
     3241 tttgtttggg tggagggtgt tttgttttgt gagacagagt ctctctgtgt agccctggct
     3301 gtcctggaat tcactctgta ggtcaggctg gcctcaaact cacaaagctc cacctgccgc
     3361 tgcctcccag atgctgccat tagaggtgtg tcccaccatg cccaagttgt tttgagacta
     3421 agcctcactc tagccagcct gaaatgcact gtgtagccca ggcttacttc cagtatatgg
     3481 tcactctgga tgcctccgcc gccttttttt tttaaatatt ttttattatt atgtattttc
     3541 ctcaattaca tttggaatgc tatcccaaag gtcccccata ccctcccccc cccccacttc
     3601 cctacccacc cattcccatt ttttggctct ggcattcccc tgtattgggg catataaagt
     3661 ttgcgtgtcc aatgggcctc tctttccagt gatggccgac taggccatct tttgatacat
     3721 atgcagctag agtcaacaac attatgcctc cgccttctaa gtgctgagat tacaggtgtg
     3781 tggctccata ccctacttca caggcgtttt aaattgggag aaatatcacg ttctagaatc
     3841 aaaattctca agcaaagata ccgcctgact cggagctaaa gttggctgac ctgctcactg
     3901 ccgttcaccc tcccggtcct ggtccctgct cgggcttgtc cctgctgtag acatgctcat
     3961 atgcgcttga tgactgtcct accccgcttt gtttctgtcc ccaaggtctc atgtcatagc
     4021 atgccctttt ctttgaactc tgtatgctga gctaaagcgc tgttttgttc tgtttctctt
     4081 aaagaggacc gggtcacctt gtttgtttct gcttttgagc atgctgattt tttcaagaga
     4141 tgtaaattta ttcatagacc acagtgcctt gacttaaccc acactgccaa ctggagcacc
     4201 agcacgcgaa tgcacaaacc ggtttaaggc actgtttctc tctgcctttt gacatgtatc
     4261 caaaaattat agcctactag catttcatct tagtatccag tcgttcagca tgatcactaa
     4321 cattccccgt acttagctgt tgtttaagta taaaaattga tatgtctata ctgtgtcttt
     4381 ctttttcctt tctggtatta agaagagcca tagctggaga gatggctctg ttttaagaat
     4441 gcatactgct cttacagagg acctggattc agttcttagt gcctaagcca ggtgtttagt
     4501 tcactgcagc ctgcagtgcc agctcctggg ggtacaatac cttcctctga tttccaaggg
     4561 cacctacgtg catgtgaaca ttctttctca cggatacaca tacacacatc atttgaaatt
     4621 aaaaaaaaaa aatcctgtga aaaacaaaaa ggaaccagaa ataagctgat tactacataa
     4681 acaattgtct acggccacct cagttcctca taggtcccct ccacacacac tgtgtgtgtt
     4741 ttctagggct aaaaaaatga gatcttgcta tcgtttctag caataaacac tttagcacat
     4801 agaggtctgg gacagaacta actcctcatg tgttttcagg gatcttattc catgtgtcac
     4861 caccaaagac ttccacagta ttataaaaca tgtaactact ctaaaatgac gtcagccctt
     4921 ggctacatcg tcttctttct cttttgtaca tttggagaaa tgcctgaacc ttaatggtat
     4981 tactataata ctgtcttata ttaactgtag ggttttttca ttggaatatt gtctgccatt
     5041 ggaggggcgg gggagacaac gaatgaagat ctaaatacag aaatctgaac acaagttcca
     5101 aagcgtgtcc tctgacctct cccttttagg ttgacttatt tgtgaaacag gtaaaatttg
     5161 agagggtcat tgttttgtgg tttgtactat ttcttaagaa acatacccta agattaaatt
     5221 ttttctgaaa agaaagtatc tttttttcct aagtacttct caagttagtc ttttagtggg
     5281 aattctgccg attaaccttg acttaacatt tttttccttc taatatatat tttttaactc
     5341 tgtgtacttt aatactttaa gtggaaataa ttttataaaa tctctgttaa atctcaagcc
     5401 ccaaatgtgg gtggctctgc atgtgtgttt tgggaaactt ttacaataaa gtaaactcat
     5461 tttattagtg gca
//
