LOCUS       NM_023697               1475 bp    mRNA    linear   ROD 01-JUN-2024
DEFINITION  Mus musculus retinol dehydrogenase 14 (all-trans and 9-cis)
            (Rdh14), mRNA.
ACCESSION   NM_023697
VERSION     NM_023697.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1475)
  AUTHORS   Sato,S., Miyazono,S., Tachibanaki,S. and Kawamura,S.
  TITLE     RDH13L, an enzyme responsible for the aldehyde-alcohol redox
            coupling reaction (AL-OL coupling reaction) to supply 11-cis
            retinal in the carp cone retinoid cycle
  JOURNAL   J Biol Chem 290 (5), 2983-2992 (2015)
   PUBMED   25533474
REFERENCE   2  (bases 1 to 1475)
  AUTHORS   Lee,J., Xu,Y., Chen,Y., Sprung,R., Kim,S.C., Xie,S. and Zhao,Y.
  TITLE     Mitochondrial phosphoproteome revealed by an improved IMAC method
            and MS/MS/MS
  JOURNAL   Mol Cell Proteomics 6 (4), 669-676 (2007)
   PUBMED   17208939
REFERENCE   3  (bases 1 to 1475)
  AUTHORS   Haeseleer,F., Jang,G.F., Imanishi,Y., Driessen,C.A.G.G.,
            Matsumura,M., Nelson,P.S. and Palczewski,K.
  TITLE     Dual-substrate specificity short chain retinol dehydrogenases from
            the vertebrate retina
  JOURNAL   J Biol Chem 277 (47), 45537-45546 (2002)
   PUBMED   12226107
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BB200972.2, AF303831.1 and BE686521.1.
            
            On May 16, 2009 this sequence version replaced NM_023697.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC092299.1, AF303831.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-8                 BB200972.2         109-116             c
            9-1130              AF303831.1         24-1145
            1131-1475           BE686521.1         1-345               c
FEATURES             Location/Qualifiers
     source          1..1475
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="12"
                     /map="12 5.29 cM"
     gene            1..1475
                     /gene="Rdh14"
                     /gene_synonym="3110030G19Rik; PAN2"
                     /note="retinol dehydrogenase 14 (all-trans and 9-cis)"
                     /db_xref="GeneID:105014"
                     /db_xref="MGI:MGI:1920402"
     exon            1..447
                     /gene="Rdh14"
                     /gene_synonym="3110030G19Rik; PAN2"
                     /inference="alignment:Splign:2.1.0"
     CDS             61..1065
                     /gene="Rdh14"
                     /gene_synonym="3110030G19Rik; PAN2"
                     /EC_number="1.1.1.300"
                     /note="alcohol dehydrogenase PAN2; alcohol dehydrogenase
                     PAN2; expressed sequence AW215439"
                     /codon_start=1
                     /product="retinol dehydrogenase 14"
                     /protein_id="NP_076186.1"
                     /db_xref="CCDS:CCDS25811.1"
                     /db_xref="GeneID:105014"
                     /db_xref="MGI:MGI:1920402"
                     /translation="MAVASVAAALLAALGGALWLAARRFSGPRNQRQQGGGDPGLMHG
                     KTVLITGANSGLGRATAAELLRLGARVIMGCRDRARAEEAAGQLRQELCQAGGAGPDG
                     TDGQLVVKELDLASLRSVRAFCQELLQEEPRLDVLINNAGVFHCPYTKTEDGFEMQFG
                     VNHLGHFLLTNLLLGLLKSSAPSRIVVVSSKLYKYGEINFEDLNSEQSYNKSFCYSRS
                     KLANILFTRELARRLEGTNVTVNVLHPGIVRTNLGRHIHIPLLARPLFNLVSWAFFKT
                     PLEGAQTSIYLACSPDVEGVSGRYFGDCKEEELLPKAMDESVARKLWDISEVMVGILK
                     "
     exon            448..1472
                     /gene="Rdh14"
                     /gene_synonym="3110030G19Rik; PAN2"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1451..1456
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Rdh14"
                     /gene_synonym="3110030G19Rik; PAN2"
                     /note="hexamer: AATAAA"
     polyA_site      1471
                     /gene="Rdh14"
                     /gene_synonym="3110030G19Rik; PAN2"
                     /note="major polyA site"
ORIGIN      
        1 gtggccccat agcactccgg aacctgtgcg ctaggcccag tgcaccgggc ccggaaggtt
       61 atggcagtgg ctagtgtggc cgcagcgctc ctggccgcac tgggcggggc gctgtggctg
      121 gcggcccggc ggttctctgg gccaagaaac cagcggcagc agggaggcgg ggacccgggc
      181 ctcatgcacg ggaagacagt gctgatcacc ggagcaaaca gcggcctggg ccgtgccacc
      241 gcggcggagc tgctccgcct gggggcgcgg gtcatcatgg gatgtcggga ccgcgctcga
      301 gcagaggagg cggccggtca gctcaggcag gagctctgtc aggctggggg cgccgggccc
      361 gacggcaccg atggccagct ggtcgttaag gagctggacc ttgcctcgct gcgctcagtg
      421 cgagctttct gccaagaact gctacaggag gagcccaggc tagacgtcct gatcaataat
      481 gcgggggttt tccactgccc gtatacgaag actgaagatg ggtttgagat gcagtttgga
      541 gtgaaccatc tgggccactt cctactcacc aatcttctcc ttggactcct caaaagttca
      601 gctcccagca ggattgtagt cgtttcttcc aaactttata aatatggaga aatcaacttt
      661 gaagacttga acagtgagca aagctataat aaaagcttct gttatagtcg aagcaaactg
      721 gctaacattc ttttcacaag agaattagcc cgtcgcttag aaggaacaaa cgtgactgtc
      781 aatgtgctgc atcctggtat tgtgcgaaca aacctaggga ggcatattca catcccactg
      841 ctggcaagac cacttttcaa tttggtatcc tgggcttttt tcaaaactcc attagaaggt
      901 gcccagactt ccatctattt agcctgttca cctgacgtag aaggtgtgtc aggaaggtac
      961 tttggagatt gtaaggagga agagctcttg cccaaagcta tggatgagtc agtggcaaga
     1021 aaactgtggg atatcagtga agtgatggtt ggcattctaa aataggagta aagagaacag
     1081 gactatgtat aggatgatcc attatacccc tggtcaggaa tggcatgttg taagcatgtg
     1141 ctacgtgaca acagtctagc cgcaatcatg ctgagaggtg cacatggata tttcaaagac
     1201 actgctacta tttggggcta atacaaagtt cagcaaagat gctatcaatg tggatcataa
     1261 ctagaatata acaattctgt tatttattat aattgggcaa ttataactgt taaagatact
     1321 ggtaatttaa aagctgtctt aagagggttt tcaaaaattt tgactttcat ggcaaatatg
     1381 ttcagaattt ttactacaat gcttgttttg tgtaaatact atgcctaatg tgtgcacata
     1441 aatcacttgg aataaatgtc tgatgtaggt ttaaa
//
