LOCUS       NM_009038               1076 bp    mRNA    linear   ROD 10-FEB-2025
DEFINITION  Mus musculus recoverin (Rcvrn), mRNA.
ACCESSION   NM_009038
VERSION     NM_009038.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1076)
  AUTHORS   Wutikeli,H., Yu,Y., Zhang,T., Cao,J., Nawy,S. and Shen,Y.
  TITLE     Role of Elavl-like RNA-binding protein in retinal development and
            signal transduction
  JOURNAL   Biochim Biophys Acta Mol Basis Dis 1871 (1), 167518 (2025)
   PUBMED   39307290
REFERENCE   2  (bases 1 to 1076)
  AUTHORS   Mori,D., Inami,C., Ikeda,R., Sawahata,M., Urata,S., Yamaguchi,S.T.,
            Kobayashi,Y., Fujita,K., Arioka,Y., Okumura,H., Kushima,I.,
            Kodama,A., Suzuki,T., Hirao,T., Yoshimi,A., Sobue,A., Ito,T.,
            Noda,Y., Mizoguchi,H., Nagai,T., Kaibuchi,K., Okabe,S.,
            Nishiguchi,K., Kume,K., Yamada,K. and Ozaki,N.
  TITLE     Mice with deficiency in Pcdh15, a gene associated with bipolar
            disorders, exhibit significantly elevated diurnal amplitudes of
            locomotion and body temperature
  JOURNAL   Transl Psychiatry 14 (1), 216 (2024)
   PUBMED   38806495
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 1076)
  AUTHORS   Li,Y., Xiao,D., Chen,H., Zheng,X.F.S. and Xiang,M.
  TITLE     Maf1 controls retinal neuron number by both RNA Pol III- and Pol
            II-dependent mechanisms
  JOURNAL   iScience 26 (12), 108544 (2023)
   PUBMED   38089586
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 1076)
  AUTHORS   Iwagawa,T., Fukushima,M., Takeuchi,S., Kawamura,Y., Aihara,Y.,
            Ozawa,M., Yakushiji-Kaminatsui,N., Aihara,M., Koseki,H., Suzuki,Y.
            and Watanabe,S.
  TITLE     The histone H3K36 demethylase Fbxl11 plays pivotal roles in the
            development of retinal late-born cell types
  JOURNAL   Genes Cells 28 (7), 482-495 (2023)
   PUBMED   37073980
REFERENCE   5  (bases 1 to 1076)
  AUTHORS   Zhang,J., Roberts,J.M., Chang,F., Schwakopf,J. and Vetter,M.L.
  TITLE     Jarid2 promotes temporal progression of retinal progenitors via
            repression of Foxp1
  JOURNAL   Cell Rep 42 (3), 112237 (2023)
   PUBMED   36924502
  REMARK    Erratum:[Cell Rep. 2023 Apr 25;42(4):112416. doi:
            10.1016/j.celrep.2023.112416.. PMID: 37043355]
REFERENCE   6  (bases 1 to 1076)
  AUTHORS   Brown,N.L., Patel,S., Brzezinski,J. and Glaser,T.
  TITLE     Math5 is required for retinal ganglion cell and optic nerve
            formation
  JOURNAL   Development 128 (13), 2497-2508 (2001)
   PUBMED   11493566
REFERENCE   7  (bases 1 to 1076)
  AUTHORS   McGinnis,J.F., Austin,B., Klisak,I., Heinzmann,C., Kojis,T.,
            Sparkes,R.S., Bateman,J.B. and Lerious,V.
  TITLE     Chromosomal assignment of the human gene for the cancer-associated
            retinopathy protein (recoverin) to chromosome 17p13.1
  JOURNAL   J Neurosci Res 40 (2), 165-168 (1995)
   PUBMED   7745609
REFERENCE   8  (bases 1 to 1076)
  AUTHORS   Kozak,C.A., Danciger,M., Bowes,C., Adamson,M.C., Palczewski,K.,
            Polans,A.S. and Farber,D.B.
  TITLE     Localization of three genes expressed in retina on mouse chromosome
            11
  JOURNAL   Mamm Genome 6 (2), 142-144 (1995)
   PUBMED   7767000
REFERENCE   9  (bases 1 to 1076)
  AUTHORS   McGinnis,J.F., Lerious,V., Pazik,J. and Elliott,R.W.
  TITLE     Chromosomal assignment of the recoverin gene and cancer-associated
            retinopathy
  JOURNAL   Mamm Genome 4 (1), 43-45 (1993)
   PUBMED   8422501
REFERENCE   10 (bases 1 to 1076)
  AUTHORS   McGinnis,J.F., Stepanik,P.L., Baehr,W., Subbaraya,I. and Lerious,V.
  TITLE     Cloning and sequencing of the 23 kDa mouse photoreceptor
            cell-specific protein
  JOURNAL   FEBS Lett 302 (2), 172-176 (1992)
   PUBMED   1386025
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            X66196.1, CK617354.1, CK617615.1 and CK627353.1.
            
            On Dec 18, 2007 this sequence version replaced NM_009038.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: X66196.1, BC110564.2 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164131, SAMN01164132
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-40                X66196.1           9-48
            41-659              CK617354.1         1-619
            660-1043            CK617615.1         26-409              c
            1044-1076           CK627353.1         18-50               c
FEATURES             Location/Qualifiers
     source          1..1076
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="11"
                     /map="11 41.13 cM"
     gene            1..1076
                     /gene="Rcvrn"
                     /gene_synonym="CAR; S-modulin"
                     /note="recoverin"
                     /db_xref="GeneID:19674"
                     /db_xref="MGI:MGI:97883"
     exon            1..472
                     /gene="Rcvrn"
                     /gene_synonym="CAR; S-modulin"
                     /inference="alignment:Splign:2.1.0"
     CDS             92..700
                     /gene="Rcvrn"
                     /gene_synonym="CAR; S-modulin"
                     /note="cancer-associated retinopathy protein; 23 kDa
                     photoreceptor cell-specific protein; guanylate cyclase
                     activator"
                     /codon_start=1
                     /product="recoverin"
                     /protein_id="NP_033064.1"
                     /db_xref="CCDS:CCDS24859.1"
                     /db_xref="GeneID:19674"
                     /db_xref="MGI:MGI:97883"
                     /translation="MGNSKSGALSKEILEELQLNTKFTEEELSAWYQSFLKECPSGRI
                     TRQEFESIYSKFFPDSDPKAYAQHVFRSFDANSDGTLDFKEYVIALHMTTAGKPTQKL
                     EWAFSLYDVDGNGTISKNEVLEIVMAIFKMIKPEDVKLLPDDENTPEKRAEKIWAFFG
                     KKEDDKLTEEEFIEGTLANKEILRLIQFEPQKVKERIKEKKQ"
     exon            473..584
                     /gene="Rcvrn"
                     /gene_synonym="CAR; S-modulin"
                     /inference="alignment:Splign:2.1.0"
     exon            585..1062
                     /gene="Rcvrn"
                     /gene_synonym="CAR; S-modulin"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1021..1026
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Rcvrn"
                     /gene_synonym="CAR; S-modulin"
                     /note="hexamer: AATAAA"
     polyA_site      1056
                     /gene="Rcvrn"
                     /gene_synonym="CAR; S-modulin"
                     /note="major polyA site"
ORIGIN      
        1 tgggtctcca ccccatagca gcacacagcc ttgttagcca ggcgaccaca cttgtccctc
       61 ccgccccccg cggcgcctac tctccctcac catggggaac agcaagagcg gtgccctgtc
      121 caaggagatc ctagaggagt tgcaactgaa caccaagttc acagaggagg agctgagtgc
      181 ctggtaccag tccttcctga aggagtgccc tagcggccgc atcacgcggc aggagttcga
      241 aagtatctat tccaagtttt tcccggactc cgaccccaag gcctacgcgc agcacgtgtt
      301 ccgcagcttc gatgccaaca gcgatggtac gctggacttc aaggagtacg tgattgctct
      361 gcacatgacc acggcgggca agcccacgca gaagctcgag tgggccttct cgctctacga
      421 cgtagacggc aatgggacca tcagcaaaaa tgaagtgctg gagatcgtca tggctatctt
      481 caaaatgatc aagcctgagg atgtgaaact cctcccagat gatgaaaaca ccccagaaaa
      541 gcgggctgag aagatctggg cattctttgg aaagaaagag gatgataaac ttacagagga
      601 ggaattcatc gaggggaccc tggccaataa ggaaattctg cgactgatcc agtttgaacc
      661 tcaaaaagtg aaggagagga taaaggaaaa gaaacagtga tgggcaccgt ttggctctcc
      721 ccccccccac ctcaccccca cacaaacacc tgcagtgtga gcattgcaag catcagcctg
      781 cgcacgcaca ccctgagtct ggagaggtgg ggaaccaaac ctctccctgc caactgaagg
      841 tccttagcag gacacaactc ctgcttcctt ttgtcttcag tgtcctcccc atccttcaca
      901 ctttacctgt ctccttctcc tgcccaggta gccctgtgat aatcccaagc ttagggcgta
      961 ggagtcctaa atatcattcc tgcttaagct cctttgggga ttgctgggta agcaggttcc
     1021 aataaatgca aaaggagttt gttgttgcga gtgcaactct aaaaaaaaaa aaaaaa
//
