LOCUS       NM_026555               1453 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus reticulocalbin 3, EF-hand calcium binding domain
            (Rcn3), transcript variant 1, mRNA.
ACCESSION   NM_026555
VERSION     NM_026555.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1453)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 1453)
  AUTHORS   Park,N.R., Shetye,S.S., Bogush,I., Keene,D.R., Tufa,S.,
            Hudson,D.M., Archer,M., Qin,L., Soslowsky,L.J., Dyment,N.A. and
            Joeng,K.S.
  TITLE     Reticulocalbin 3 is involved in postnatal tendon development by
            regulating collagen fibrillogenesis and cellular maturation
  JOURNAL   Sci Rep 11 (1), 10868 (2021)
   PUBMED   34035379
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 1453)
  AUTHORS   Shi,X., An,X., Yang,L., Wu,Z., Zan,D., Li,Z., Pang,B., Chen,Y.,
            Li,J., Tan,P., Ma,R.Z., Fang,Q., Ma,Y. and Jin,J.
  TITLE     Reticulocalbin 3 deficiency in alveolar epithelium attenuated
            LPS-induced ALI via NF-kappaB signaling
  JOURNAL   Am J Physiol Lung Cell Mol Physiol 320 (4), L627-L639 (2021)
   PUBMED   33625944
REFERENCE   4  (bases 1 to 1453)
  AUTHORS   Jin,J., Shi,X., Li,Y., Zhang,Q., Guo,Y., Li,C., Tan,P., Fang,Q.,
            Ma,Y. and Ma,R.Z.
  TITLE     Reticulocalbin 3 Deficiency in Alveolar Epithelium Exacerbated
            Bleomycin-induced Pulmonary Fibrosis
  JOURNAL   Am J Respir Cell Mol Biol 59 (3), 320-333 (2018)
   PUBMED   29676583
REFERENCE   5  (bases 1 to 1453)
  AUTHORS   Jin,J., Li,Y., Ren,J., Man Lam,S., Zhang,Y., Hou,Y., Zhang,X.,
            Xu,R., Shui,G. and Ma,R.Z.
  TITLE     Neonatal Respiratory Failure with Retarded Perinatal Lung
            Maturation in Mice Caused by Reticulocalbin 3 Disruption
  JOURNAL   Am J Respir Cell Mol Biol 54 (3), 410-423 (2016)
   PUBMED   26252542
  REMARK    GeneRIF: Results indicate an essential role of Rcn3 in perinatal
            lung maturation and neonatal respiratory adaptation as well as shed
            additional light on the mechanism of neonatal respiratory distress
            syndrome development.
REFERENCE   6  (bases 1 to 1453)
  AUTHORS   Koscielny,G., Yaikhom,G., Iyer,V., Meehan,T.F., Morgan,H.,
            Atienza-Herrero,J., Blake,A., Chen,C.K., Easty,R., Di Fenza,A.,
            Fiegel,T., Grifiths,M., Horne,A., Karp,N.A., Kurbatova,N.,
            Mason,J.C., Matthews,P., Oakley,D.J., Qazi,A., Regnart,J.,
            Retha,A., Santos,L.A., Sneddon,D.J., Warren,J., Westerberg,H.,
            Wilson,R.J., Melvin,D.G., Smedley,D., Brown,S.D., Flicek,P.,
            Skarnes,W.C., Mallon,A.M. and Parkinson,H.
  TITLE     The International Mouse Phenotyping Consortium Web Portal, a
            unified point of access for knockout mice and related phenotyping
            data
  JOURNAL   Nucleic Acids Res 42 (Database issue), D802-D809 (2014)
   PUBMED   24194600
REFERENCE   7  (bases 1 to 1453)
  AUTHORS   Hoffman,B.G., Zavaglia,B., Witzsche,J., Ruiz de Algara,T.,
            Beach,M., Hoodless,P.A., Jones,S.J., Marra,M.A. and Helgason,C.D.
  TITLE     Identification of transcripts with enriched expression in the
            developing and adult pancreas
  JOURNAL   Genome Biol 9 (6), R99 (2008)
   PUBMED   18554416
REFERENCE   8  (bases 1 to 1453)
  AUTHORS   Jensen,P., Magdaleno,S., Lehman,K.M., Rice,D.S., Lavallie,E.R.,
            Collins-Racie,L., McCoy,J.M. and Curran,T.
  TITLE     A neurogenomics approach to gene expression analysis in the
            developing brain
  JOURNAL   Brain Res Mol Brain Res 132 (2), 116-127 (2004)
   PUBMED   15582152
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BY248337.1, AK077943.1 and AV129283.1.
            
            On May 14, 2008 this sequence version replaced NM_026555.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC025602.1, AK086705.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849376
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-61                BY248337.1         3-63
            62-1444             AK077943.1         2-1384
            1445-1453           AV129283.1         126-134
FEATURES             Location/Qualifiers
     source          1..1453
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="7"
                     /map="7 29.11 cM"
     gene            1..1453
                     /gene="Rcn3"
                     /gene_synonym="6030455P07Rik; D530026G20Rik; D7Ertd671e;
                     RLP49"
                     /note="reticulocalbin 3, EF-hand calcium binding domain"
                     /db_xref="GeneID:52377"
                     /db_xref="MGI:MGI:1277122"
     exon            1..118
                     /gene="Rcn3"
                     /gene_synonym="6030455P07Rik; D530026G20Rik; D7Ertd671e;
                     RLP49"
                     /inference="alignment:Splign:2.1.0"
     exon            119..366
                     /gene="Rcn3"
                     /gene_synonym="6030455P07Rik; D530026G20Rik; D7Ertd671e;
                     RLP49"
                     /inference="alignment:Splign:2.1.0"
     exon            367..569
                     /gene="Rcn3"
                     /gene_synonym="6030455P07Rik; D530026G20Rik; D7Ertd671e;
                     RLP49"
                     /inference="alignment:Splign:2.1.0"
     exon            570..742
                     /gene="Rcn3"
                     /gene_synonym="6030455P07Rik; D530026G20Rik; D7Ertd671e;
                     RLP49"
                     /inference="alignment:Splign:2.1.0"
     exon            743..803
                     /gene="Rcn3"
                     /gene_synonym="6030455P07Rik; D530026G20Rik; D7Ertd671e;
                     RLP49"
                     /inference="alignment:Splign:2.1.0"
     exon            804..1003
                     /gene="Rcn3"
                     /gene_synonym="6030455P07Rik; D530026G20Rik; D7Ertd671e;
                     RLP49"
                     /inference="alignment:Splign:2.1.0"
     exon            1004..1453
                     /gene="Rcn3"
                     /gene_synonym="6030455P07Rik; D530026G20Rik; D7Ertd671e;
                     RLP49"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1425..1430
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Rcn3"
                     /gene_synonym="6030455P07Rik; D530026G20Rik; D7Ertd671e;
                     RLP49"
                     /note="hexamer: AATAAA"
     polyA_site      1444
                     /gene="Rcn3"
                     /gene_synonym="6030455P07Rik; D530026G20Rik; D7Ertd671e;
                     RLP49"
                     /note="major polyA site"
ORIGIN      
        1 gagggcggca gcctctggac ggctggtgga ggagcttaac tggaacctgg ccaggttggg
       61 catctttgtg cgaaagcaga gctcagcgta gggagctaac tcaggccggg taacagagga
      121 accgatgatg tggcgatggt cgtttctgtt gcttctctta ctgctgaggc actgggccct
      181 cgggaagcca tcccctgatg caggacctca tggccaggat agggtccatc atggaacccc
      241 cctgagcgag gccccccacg atgacgccca cgggaatttc cagtacgacc atgaggcgtt
      301 cctgggacga gacgtggcca aggaatttga caaactcagc ccagaggaaa gccaggcccg
      361 acttgggcgg atcgtagacc gcatggatct tgctggggac agcgacggct gggtgtcctt
      421 agctgagctc cgcgcgtgga tcgcgcacac acagcagcgg cacatccgtg actcggtgag
      481 cgcagcctgg cacacctacg acacggaccg cgacgggcgc gtgggttggg aggagttgcg
      541 caatgccacc tatggccatt atgagcccgg agaggagttt catgatgtgg aggatgccga
      601 gacctacaag aagatgctgg ctcgggatga gcggcgattc cgggtagccg accaagatgg
      661 cgactccatg gctactcggg aagagctgac ggcctttctg catccggagg agttccctca
      721 catgcgggac atcgtggtag cagagaccct ggaggacctt gacaagaaca aagatggcta
      781 cgtgcaggtg gaagagtata tcgcggacct gtactccgag gagcctgggg aggaggaacc
      841 tgcctgggtg cagacagagc ggcagcagtt ccgagagttc cgggatctga acaaggacgg
      901 gcgactggat ggcagtgaag tcggttactg ggtgctgcct ccatcccagg accagcccct
      961 ggtggaggcc aaccacctgc tgcatgagag cgacacggac aaggatggcc ggctgagcaa
     1021 agctgagatc ttgagcaact ggaacatgtt tgtgggcagc caggccacca actacggtga
     1081 ggacctgaca aggcaccatg atgagctctg atccccatgt ctctcagact tccgaccaca
     1141 tgaccacatg ggggacaacc gcggggccac tgcagccagc cccgccccca ggacacagac
     1201 tcagctctgg tgttcctggt tcttgggccc tcagtcacct tctctccctg agacccctgt
     1261 caccaaccct gggacccccc aacctgccca ggatactcag gcactcaaag ataagtgaca
     1321 cccactgata gcatcccagc actgacgcgg ggccacatcc tgacctaacc gcaatttgaa
     1381 ctctgaatgt caacagcaca agctaacctg tcctgcctag gagcaataaa agctgttgct
     1441 ggggtcccct gct
//
