LOCUS       NM_001042674            2465 bp    mRNA    linear   ROD 10-DEC-2024
DEFINITION  Mus musculus RNA binding protein gene with multiple splicing
            (Rbpms), transcript variant 2, mRNA.
ACCESSION   NM_001042674
VERSION     NM_001042674.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2465)
  AUTHORS   Wutikeli,H., Yu,Y., Zhang,T., Cao,J., Nawy,S. and Shen,Y.
  TITLE     Role of Elavl-like RNA-binding protein in retinal development and
            signal transduction
  JOURNAL   Biochim Biophys Acta Mol Basis Dis 1871 (1), 167518 (2025)
   PUBMED   39307290
REFERENCE   2  (bases 1 to 2465)
  AUTHORS   Mehta,K., Daghsni,M., Raeisossadati,R., Xu,Z., Davis,E.,
            Naidich,A., Wang,B., Tao,S., Pi,S., Chen,W., Kostka,D., Liu,S.,
            Gross,J.M., Kuwajima,T. and Aldiri,I.
  TITLE     A cis-regulatory module underlies retinal ganglion cell genesis and
            axonogenesis
  JOURNAL   Cell Rep 43 (6), 114291 (2024)
   PUBMED   38823017
REFERENCE   3  (bases 1 to 2465)
  AUTHORS   Meng,M., Chaqour,B., O'Neill,N., Dine,K., Sarabu,N., Ying,G.S.,
            Shindler,K.S. and Ross,A.G.
  TITLE     Comparison of Brn3a and RBPMS Labeling to Assess Retinal Ganglion
            Cell Loss During Aging and in a Model of Optic Neuropathy
  JOURNAL   Invest Ophthalmol Vis Sci 65 (4), 19 (2024)
   PUBMED   38587440
  REMARK    GeneRIF: Comparison of Brn3a and RBPMS Labeling to Assess Retinal
            Ganglion Cell Loss During Aging and in a Model of Optic Neuropathy.
REFERENCE   4  (bases 1 to 2465)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   5  (bases 1 to 2465)
  AUTHORS   Li,Y., Xiao,D., Chen,H., Zheng,X.F.S. and Xiang,M.
  TITLE     Maf1 controls retinal neuron number by both RNA Pol III- and Pol
            II-dependent mechanisms
  JOURNAL   iScience 26 (12), 108544 (2023)
   PUBMED   38089586
  REMARK    Publication Status: Online-Only
REFERENCE   6  (bases 1 to 2465)
  AUTHORS   Stryke,D., Kawamoto,M., Huang,C.C., Johns,S.J., King,L.A.,
            Harper,C.A., Meng,E.C., Lee,R.E., Yee,A., L'Italien,L.,
            Chuang,P.T., Young,S.G., Skarnes,W.C., Babbitt,P.C. and Ferrin,T.E.
  TITLE     BayGenomics: a resource of insertional mutations in mouse embryonic
            stem cells
  JOURNAL   Nucleic Acids Res 31 (1), 278-281 (2003)
   PUBMED   12520002
REFERENCE   7  (bases 1 to 2465)
  AUTHORS   Mu,X., Zhao,S., Pershad,R., Hsieh,T.F., Scarpa,A., Wang,S.W.,
            White,R.A., Beremand,P.D., Thomas,T.L., Gan,L. and Klein,W.H.
  TITLE     Gene expression in the developing mouse retina by EST sequencing
            and microarray analysis
  JOURNAL   Nucleic Acids Res 29 (24), 4983-4993 (2001)
   PUBMED   11812828
REFERENCE   8  (bases 1 to 2465)
  AUTHORS   Bruneau,B.G., Bao,Z.Z., Fatkin,D., Xavier-Neto,J.,
            Georgakopoulos,D., Maguire,C.T., Berul,C.I., Kass,D.A., Kuroski-de
            Bold,M.L., de Bold,A.J., Conner,D.A., Rosenthal,N., Cepko,C.L.,
            Seidman,C.E. and Seidman,J.G.
  TITLE     Cardiomyopathy in Irx4-deficient mice is preceded by abnormal
            ventricular gene expression
  JOURNAL   Mol Cell Biol 21 (5), 1730-1736 (2001)
   PUBMED   11238910
REFERENCE   9  (bases 1 to 2465)
  AUTHORS   Araki,K., Imaizumi,T., Sekimoto,T., Yoshinobu,K., Yoshimuta,J.,
            Akizuki,M., Miura,K., Araki,M. and Yamamura,K.
  TITLE     Exchangeable gene trap using the Cre/mutated lox system
  JOURNAL   Cell Mol Biol (Noisy-le-grand) 45 (5), 737-750 (1999)
   PUBMED   10512203
REFERENCE   10 (bases 1 to 2465)
  AUTHORS   Gerber,W.V., Yatskievych,T.A., Antin,P.B., Correia,K.M.,
            Conlon,R.A. and Krieg,P.A.
  TITLE     The RNA-binding protein gene, hermes, is expressed at high levels
            in the developing heart
  JOURNAL   Mech Dev 80 (1), 77-86 (1999)
   PUBMED   10096065
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC162523.9, AK041118.1 and AK003434.1.
            
            On Oct 31, 2013 this sequence version replaced NM_001042674.1.
            
            Transcript Variant: This variant (2) differs in the 3' UTR,
            compared to variant 1. Variants 1 and 2 encode the same protein
            (isoform 1).
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK041118.1, SRR7345562.4543836.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849380, SAMN00849381
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-57                AC162523.9         44574-44630
            58-2215             AK041118.1         2-2159
            2216-2465           AK003434.1         1273-1522
FEATURES             Location/Qualifiers
     source          1..2465
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="8"
                     /map="8 20.85 cM"
     gene            1..2465
                     /gene="Rbpms"
                     /gene_synonym="2010300K22Rik; 2700019M19Rik; hermes;
                     RBP-MS"
                     /note="RNA binding protein gene with multiple splicing"
                     /db_xref="GeneID:19663"
                     /db_xref="MGI:MGI:1334446"
     exon            1..388
                     /gene="Rbpms"
                     /gene_synonym="2010300K22Rik; 2700019M19Rik; hermes;
                     RBP-MS"
                     /inference="alignment:Splign:2.1.0"
     exon            389..466
                     /gene="Rbpms"
                     /gene_synonym="2010300K22Rik; 2700019M19Rik; hermes;
                     RBP-MS"
                     /inference="alignment:Splign:2.1.0"
     exon            467..505
                     /gene="Rbpms"
                     /gene_synonym="2010300K22Rik; 2700019M19Rik; hermes;
                     RBP-MS"
                     /inference="alignment:Splign:2.1.0"
     exon            506..568
                     /gene="Rbpms"
                     /gene_synonym="2010300K22Rik; 2700019M19Rik; hermes;
                     RBP-MS"
                     /inference="alignment:Splign:2.1.0"
     exon            569..719
                     /gene="Rbpms"
                     /gene_synonym="2010300K22Rik; 2700019M19Rik; hermes;
                     RBP-MS"
                     /inference="alignment:Splign:2.1.0"
     exon            720..853
                     /gene="Rbpms"
                     /gene_synonym="2010300K22Rik; 2700019M19Rik; hermes;
                     RBP-MS"
                     /inference="alignment:Splign:2.1.0"
     exon            854..922
                     /gene="Rbpms"
                     /gene_synonym="2010300K22Rik; 2700019M19Rik; hermes;
                     RBP-MS"
                     /inference="alignment:Splign:2.1.0"
     exon            923..2465
                     /gene="Rbpms"
                     /gene_synonym="2010300K22Rik; 2700019M19Rik; hermes;
                     RBP-MS"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1015..1020
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Rbpms"
                     /gene_synonym="2010300K22Rik; 2700019M19Rik; hermes;
                     RBP-MS"
                     /note="hexamer: AATAAA"
     polyA_site      1045
                     /gene="Rbpms"
                     /gene_synonym="2010300K22Rik; 2700019M19Rik; hermes;
                     RBP-MS"
                     /note="major polyA site"
ORIGIN      
        1 gggaggggag gagggaggaa ggcgagagaa agcgcgctgc gtgcggcccc gctgcccaga
       61 gcctgccagc agcgcgtcct cggcggctcc ggtcccaacc gcgcccgccg cctcgcctcc
      121 tcggtctcgg ccgcgtcccg actccggggc tcgcccggcc tctcggaggt ccccgcccgc
      181 cggtccgtct cggctctccg ctgcgccgcc cggctccagc cccgcagccc gccccggggg
      241 aaggtagcag cgggcgagcg cgccctcgcc ctcgcctcca accccgcgcc ccagtcccgc
      301 gcggcgacga aggaccggga agatgaacgg cggcggcaaa gccgagaagg agaacacccc
      361 gagcgaggcc aaccttcagg aggaggaggt ccggacccta tttgtcagcg gtctgcctct
      421 ggacatcaag ccccgagagc tgtacctgct cttcagacca ttcaagggct atgaaggttc
      481 tctcataaag ctcacatcta aacagcccgt aggctttgtc agttttgaca gtcgctcaga
      541 agcagaggcc gcaaagaacg ctttgaacgg catccgcttc gatcctgaaa tcccgcaaac
      601 gctacgacta gagtttgcta aggcaaacac gaagatggcc aagaacaaac tcgtagggac
      661 tccaaacccc agtactcctc tgcccaacac tgtacctcag ttcattgcca gggagccata
      721 tgagctcaca gtacctgcac tttaccccag tagccctgaa gtttgggccc cgtaccctct
      781 gtacccagcg gagttagcgc ctgctcttcc tcctcctgcc gctttcacct accccgcttc
      841 actgcatgcc cagatgcgct ggatccctcc ctccgaggcc acttcccagg gctggaagtc
      901 ccggcagttc tgctgaggct gtgcttgaaa acaccctgcc ccgttttgac cccttcaaga
      961 cttcacaaca gcctctatca cacatctgtt ttcctcaaag aaaaaaatat atataataaa
     1021 atgtgttttg ctcttttaca ctgtataatt ttaagaaatg tgttatttgt gaatgcatgg
     1081 tctgacattt ctgtacagtt tgaagacata gaacaaagac agcaacagta aagccaagat
     1141 cgttagtatt tttataaaga cattttaaga atggacagat ggattcttac actaggttat
     1201 atcacgactt ttcgcttgag ttttgaatgc ttttaatggt gtttatctta tttttcttct
     1261 gaaataagat gcatgtttga agcatatctc tagcatcaaa attttccaca attgtgttgt
     1321 aaatgtgtgg actccctctg cctggcccag tgtcaggccc tgttattagt aacgcggtgt
     1381 agaaatgagc ttctgcagta ctagctctgt aatcctggct cccagggatc tctctgcaag
     1441 acaatcagtg cccccaagag catttgccat tgtagtatat tcaccactgg gcaaagacta
     1501 cttaggtaat gtctctgaaa cccatggcca ctccagctga gactatacca actgtgccca
     1561 gggacatagt gacattctat acttagcatt tatgatagca ccctcagagt gtgtaaccta
     1621 atatatatca cccaccttcc ataaactgtc tccatttccc cagtggaacc ttatatttaa
     1681 ggggagggac cttagtttgg aggtaaccat tgcctcaaga ggagcaggcc ctgcccactc
     1741 agcctgcagt ggacatcaca tctctctcaa gtgattcagc aaagcattgg cctacctgag
     1801 tagctagctg gtctggcagc catgtcagat agaccgccca tcatgttctc tggacgtgct
     1861 catcttgaga ctacctacta cattgcacag ggcagggaat gaaacagtgg ccctctgcaa
     1921 tgaataccct tgcttcaaga cttcaaggcc caaagttagt cttgtgttat gtgcaacaca
     1981 tttccagagg ctgtgacagc acagcctctc ctgctcctca aaaaagagct atgtattatt
     2041 atgttgacct cagaattccc agctgctgtt actagacata atcacaatct ttgtatcttt
     2101 gtttttgatc tgcttgtgtt gtgttgaaaa gggtcatatt ttaatgattt ttgtcagtgg
     2161 tttgggaggg ttatttcatt atttttcatg agaagtaatg tcaagttttt aaaggtttaa
     2221 aaaaagaaac accaaggcct ggaatatggg ccttttcact gtaaactaga ggacgggggc
     2281 aggcagcact gggaacttag acatccaagc tggtgttcag ggactgctca tggccccagc
     2341 ccccgtgcca cttgactgtg agactcctac ttgctttatc atcaattatg cttttataaa
     2401 ttgtgtaaag gtacttttgt attgtcattt tttaaaaaaa ataataaaag tttattccag
     2461 ccatt
//
