LOCUS       NM_001166384            1580 bp    mRNA    linear   ROD 15-DEC-2024
DEFINITION  Mus musculus RNA binding motif protein, Y chromosome (Rbmy),
            transcript variant 2, mRNA.
ACCESSION   NM_001166384
VERSION     NM_001166384.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1580)
  AUTHORS   Kazi,S., Castaneda,J.M., Savolainen,A., Xu,Y., Liu,N., Qiao,H.,
            Ramirez-Solis,R., Nozawa,K., Yu,Z., Matzuk,M.M. and
            Prunskaite-Hyyrylainen,R.
  TITLE     MRNIP interacts with sex body chromatin to support meiotic
            progression, spermatogenesis, and male fertility in mice
  JOURNAL   FASEB J 36 (9), e22479 (2022)
   PUBMED   35920200
REFERENCE   2  (bases 1 to 1580)
  AUTHORS   Sampath Kumar,A., Seah,M.K., Ling,K.Y., Wang,Y., Tan,J.H.,
            Nitsch,S., Lim,S.L., Lorthongpanich,C., Wollmann,H., Low,D.H.,
            Guccione,E. and Messerschmidt,D.M.
  TITLE     Loss of maternal Trim28 causes male-predominant early embryonic
            lethality
  JOURNAL   Genes Dev 31 (1), 12-17 (2017)
   PUBMED   28115466
REFERENCE   3  (bases 1 to 1580)
  AUTHORS   Nagamachi,A., Matsui,H., Asou,H., Ozaki,Y., Aki,D., Kanai,A.,
            Takubo,K., Suda,T., Nakamura,T., Wolff,L., Honda,H. and Inaba,T.
  TITLE     Haploinsufficiency of SAMD9L, an endosome fusion facilitator,
            causes myeloid malignancies in mice mimicking human diseases with
            monosomy 7
  JOURNAL   Cancer Cell 24 (3), 305-317 (2013)
   PUBMED   24029230
REFERENCE   4  (bases 1 to 1580)
  AUTHORS   Wang,Q., Liu,X., Tang,N., Archambeault,D.R., Li,J., Song,H.,
            Tang,C., He,B., Matzuk,M.M. and Wang,Y.
  TITLE     GASZ promotes germ cell derivation from embryonic stem cells
  JOURNAL   Stem Cell Res 11 (2), 845-860 (2013)
   PUBMED   23816659
REFERENCE   5  (bases 1 to 1580)
  AUTHORS   Yao,C.J., Xu,W.J., Gong,X.L., Zhou,Y., Yan,Z.Q., Zhu,Z.J.,
            Wang,Z.X., Li,Q.L., Guo,X.B., Wang,L.Y., Ma,D. and Qiao,Z.D.
  TITLE     The role of Dby mRNA in early development of male mouse zygotes
  JOURNAL   Asian J Androl 12 (4), 567-577 (2010)
   PUBMED   20543856
REFERENCE   6  (bases 1 to 1580)
  AUTHORS   Mahadevaiah,S.K., Odorisio,T., Elliott,D.J., Rattigan,A., Szot,M.,
            Laval,S.H., Washburn,L.L., McCarrey,J.R., Cattanach,B.M.,
            Lovell-Badge,R. and Burgoyne,P.S.
  TITLE     Mouse homologues of the human AZF candidate gene RBM are expressed
            in spermatogonia and spermatids, and map to a Y chromosome deletion
            interval associated with a high incidence of sperm abnormalities
  JOURNAL   Hum Mol Genet 7 (4), 715-727 (1998)
   PUBMED   9499427
REFERENCE   7  (bases 1 to 1580)
  AUTHORS   Brown,G.M., Furlong,R.A., Sargent,C.A., Erickson,R.P.,
            Longepied,G., Mitchell,M., Jones,M.H., Hargreave,T.B., Cooke,H.J.
            and Affara,N.A.
  TITLE     Characterisation of the coding sequence and fine mapping of the
            human DFFRY gene and comparative expression analysis and mapping to
            the Sxrb interval of the mouse Y chromosome of the Dffry gene
  JOURNAL   Hum Mol Genet 7 (1), 97-107 (1998)
   PUBMED   9384609
REFERENCE   8  (bases 1 to 1580)
  AUTHORS   Elliott,D.J., Ma,K., Kerr,S.M., Thakrar,R., Speed,R., Chandley,A.C.
            and Cooke,H.
  TITLE     An RBM homologue maps to the mouse Y chromosome and is expressed in
            germ cells
  JOURNAL   Hum Mol Genet 5 (7), 869-874 (1996)
   PUBMED   8817321
REFERENCE   9  (bases 1 to 1580)
  AUTHORS   Laval,S.H., Glenister,P.H., Rasberry,C., Thornton,C.E.,
            Mahadevaiah,S.K., Cooke,H.J., Burgoyne,P.S. and Cattanach,B.M.
  TITLE     Y chromosome short arm-Sxr recombination in XSxr/Y males causes
            deletion of Rbm and XY female sex reversal
  JOURNAL   Proc Natl Acad Sci U S A 92 (22), 10403-10407 (1995)
   PUBMED   7479793
REFERENCE   10 (bases 1 to 1580)
  AUTHORS   Ma,K., Inglis,J.D., Sharkey,A., Bickmore,W.A., Hill,R.E.,
            Prosser,E.J., Speed,R.M., Thomson,E.J., Jobling,M., Taylor,K. et
            al.
  TITLE     A Y chromosome gene family with RNA-binding protein homology:
            candidates for the azoospermia factor AZF controlling human
            spermatogenesis
  JOURNAL   Cell 75 (7), 1287-1295 (1993)
   PUBMED   8269511
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK016258.1 and AC132601.4.
            
            Transcript Variant: This variant (2) differs in the 5' UTR compared
            to variant 1. Both variants 1 and 2 encode the same protein.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR5189685.123475.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849384 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on expression, longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-339               AK016258.1         4-342
            340-340             AC132601.4         146403-146403
            341-668             AK016258.1         344-671
            669-715             AC132601.4         149149-149195
            716-733             AK016258.1         719-736
            734-805             AC132601.4         150581-150652
            806-937             AK016258.1         808-939
            938-1580            AC132601.4         152241-152883
FEATURES             Location/Qualifiers
     source          1..1580
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="Y"
                     /map="Y"
     gene            1..1580
                     /gene="Rbmy"
                     /gene_synonym="RBM; Rbm1; Rbm1-rs1; Rbmy1a1; Rbmy1a1-rs1;
                     Rbmy1b"
                     /note="RNA binding motif protein, Y chromosome"
                     /db_xref="GeneID:19657"
                     /db_xref="MGI:MGI:104732"
     exon            1..72
                     /gene="Rbmy"
                     /gene_synonym="RBM; Rbm1; Rbm1-rs1; Rbmy1a1; Rbmy1a1-rs1;
                     Rbmy1b"
                     /inference="alignment:Splign:2.1.0"
     exon            73..185
                     /gene="Rbmy"
                     /gene_synonym="RBM; Rbm1; Rbm1-rs1; Rbmy1a1; Rbmy1a1-rs1;
                     Rbmy1b"
                     /inference="alignment:Splign:2.1.0"
     CDS             77..1219
                     /gene="Rbmy"
                     /gene_synonym="RBM; Rbm1; Rbm1-rs1; Rbmy1a1; Rbmy1a1-rs1;
                     Rbmy1b"
                     /note="RNA-binding motif protein, Y chromosome, family 1
                     member A1; RNA-binding motif protein, Y chromosome, family
                     1 member B; RNA-binding motif protein 1; y chromosome RNA
                     recognition motif 1; RNA binding motif protein, Y
                     chromosome, family 1, member A1, related sequence 1"
                     /codon_start=1
                     /product="RNA-binding motif protein, Y chromosome"
                     /protein_id="NP_001159856.1"
                     /db_xref="CCDS:CCDS30546.1"
                     /db_xref="GeneID:19657"
                     /db_xref="MGI:MGI:104732"
                     /translation="MAETNQPGKIFIGGLNIKTRQKTLQEIFGRFGPVARVILMRDRE
                     TKKSRGFAFLTFRRLADAKNAVKEMNGVILDGKRIKVKQARRPSSLESGSKKRPPSFS
                     RTRGASRILKCGRGGRSRARSGPSCEGNLGGDRYTPNFNVSSSGRHFAVKRNPSSKRD
                     DPPSKRSATSAQTRSNTGLRGREPHRREISRNMPRGEPASSRRDEYPLPRDYGQSSND
                     RKYESTSRGYCDYGNYHSREESASKVFSDHAGYLGGRDRDFSEYLSGNSYRDTYRSYG
                     RFHEAPSARGGNNRYDDYSNSQDGYGGRGEPYISNRSNIYSSDYERSGRQEVLPPPID
                     REYFDREGRQERGHSPKDGLYSASRESYSSNTKIWGIPWRSWRKQI"
     exon            186..292
                     /gene="Rbmy"
                     /gene_synonym="RBM; Rbm1; Rbm1-rs1; Rbmy1a1; Rbmy1a1-rs1;
                     Rbmy1b"
                     /inference="alignment:Splign:2.1.0"
     exon            293..470
                     /gene="Rbmy"
                     /gene_synonym="RBM; Rbm1; Rbm1-rs1; Rbmy1a1; Rbmy1a1-rs1;
                     Rbmy1b"
                     /inference="alignment:Splign:2.1.0"
     exon            471..623
                     /gene="Rbmy"
                     /gene_synonym="RBM; Rbm1; Rbm1-rs1; Rbmy1a1; Rbmy1a1-rs1;
                     Rbmy1b"
                     /inference="alignment:Splign:2.1.0"
     exon            624..732
                     /gene="Rbmy"
                     /gene_synonym="RBM; Rbm1; Rbm1-rs1; Rbmy1a1; Rbmy1a1-rs1;
                     Rbmy1b"
                     /inference="alignment:Splign:2.1.0"
     exon            733..813
                     /gene="Rbmy"
                     /gene_synonym="RBM; Rbm1; Rbm1-rs1; Rbmy1a1; Rbmy1a1-rs1;
                     Rbmy1b"
                     /inference="alignment:Splign:2.1.0"
     exon            814..902
                     /gene="Rbmy"
                     /gene_synonym="RBM; Rbm1; Rbm1-rs1; Rbmy1a1; Rbmy1a1-rs1;
                     Rbmy1b"
                     /inference="alignment:Splign:2.1.0"
     exon            903..1580
                     /gene="Rbmy"
                     /gene_synonym="RBM; Rbm1; Rbm1-rs1; Rbmy1a1; Rbmy1a1-rs1;
                     Rbmy1b"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 tcattttgga gtcggagttg ttgcaggacg gtgtgatcca ttaaagctga gaaaatagaa
       61 aatcaagaaa agaaaaatgg cagaaactaa tcagcctggg aaaattttta taggaggcct
      121 caacataaag accagacaaa agactcttca agaaatattt gggagatttg gaccagtagc
      181 acgtgttatt ttgatgagag atcgtgaaac taagaagtct agaggctttg ctttccttac
      241 tttccgacgc cttgcagatg ctaagaatgc tgtcaaagaa atgaatggag tgattttgga
      301 tggaaaaaga attaaagtaa aacaagccag gagaccatca tcacttgaaa gtggtagcaa
      361 gaagagacca ccatcctttt caagaaccag aggtgcttca agaattctga aatgtggaag
      421 aggaggaaga agcagagcaa gaagtggtcc ttcatgtgaa gggaacttgg gtggtgatag
      481 atatactcct aatttcaatg tgagttcttc tgggagacac tttgcagtta aaagaaatcc
      541 atcttcaaaa agggatgatc ccccttctaa aagatctgca acttctgctc agacaagaag
      601 caatactgga ctaagaggac gagaaccaca tcgaagagag atttctagaa atatgccaag
      661 aggagagccg gcgtcttcca gaagagatga gtatccatta ccaagggatt atggccagtc
      721 ttctaatgat aggaaatatg aatcaacatc cagaggatac tgtgactatg gcaattacca
      781 ctctcgggaa gaaagtgcat ctaaagtctt cagtgatcat gctggctatc ttggaggacg
      841 tgatagagat ttctctgaat atttaagtgg aaattcatac agagatacat acagaagtta
      901 tggaagattc catgaggcac catctgcaag aggtggaaac aaccgctatg atgactatag
      961 taactcacaa gatggatatg gtggaagagg agaaccatac ataagcaacc gaagtaacat
     1021 atactcaagt gactatgaac gtagtggtag acaagaagtg cttccaccac ctattgatag
     1081 ggaatacttt gaccgtgagg gcagacagga aagagggcat tcacctaagg atgggctgta
     1141 tagtgcatct cgtgaatcat acagtagtaa taccaagatt tgggggatcc catggaggtc
     1201 gtggagaaag cagatataaa gtggaggcag gtactaaagt cttaagttgt gtaccaaaca
     1261 gcatttctaa gaagaaaaat aagatgttat tcctatgttc tccaaatgtt aaaagaaata
     1321 tgttgattta ggagataagg caaatagtaa gttttactgc cttacccgaa tacggaaata
     1381 cattgttttg gggggaagtg aaataatgac taacattcca cccatgaatt cttctagaac
     1441 ataaaacaag gaaactttaa ctgttcagaa atgattcttt gttaagaaag acttgttaat
     1501 gttaaagtag aatttaccag tagagatgaa gtatttgcat agtcaaaaac aatctgtcaa
     1561 taaaaagtaa agcaaagcca
//
