LOCUS       NM_153405               1904 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus RNA binding motif protein 45 (Rbm45), mRNA.
ACCESSION   NM_153405 XM_001052100 XM_001052101 XM_001052102
VERSION     NM_153405.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1904)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 1904)
  AUTHORS   Wang,C., Chen,Z., Yi,Y., Ding,Y., Xu,F., Kang,H., Lin,K., Shu,X.,
            Zhong,Z., Zhang,Z., Liu,J., Xu,Z., Liu,L., He,X., Chang,Y. and
            Zhao,Q.
  TITLE     RBM45 reprograms lipid metabolism promoting hepatocellular
            carcinoma via Rictor and ACSL1/ACSL4
  JOURNAL   Oncogene 43 (5), 328-340 (2024)
   PUBMED   38040804
  REMARK    GeneRIF: RBM45 reprograms lipid metabolism promoting hepatocellular
            carcinoma via Rictor and ACSL1/ACSL4.
REFERENCE   3  (bases 1 to 1904)
  AUTHORS   Jacobs,F.M., van der Linden,A.J., Wang,Y., von Oerthel,L.,
            Sul,H.S., Burbach,J.P. and Smidt,M.P.
  TITLE     Identification of Dlk1, Ptpru and Klhl1 as novel Nurr1 target genes
            in meso-diencephalic dopamine neurons
  JOURNAL   Development 136 (14), 2363-2373 (2009)
   PUBMED   19515692
REFERENCE   4  (bases 1 to 1904)
  AUTHORS   Pyo,J.O., Nah,J., Kim,H.J., Chang,J.W., Song,Y.W., Yang,D.K.,
            Jo,D.G., Kim,H.R., Chae,H.J., Chae,S.W., Hwang,S.Y., Kim,S.J.,
            Kim,H.J., Cho,C., Oh,C.G., Park,W.J. and Jung,Y.K.
  TITLE     Protection of cardiomyocytes from ischemic/hypoxic cell death via
            Drbp1 and pMe2GlyDH in cardio-specific ARC transgenic mice
  JOURNAL   J Biol Chem 283 (45), 30707-30714 (2008)
   PUBMED   18782777
  REMARK    GeneRIF: ARC may protect cardiomyocytes from hypoxic cell death by
            regulating its downstream, Drbp1 and pMe(2)GlyDH
REFERENCE   5  (bases 1 to 1904)
  AUTHORS   McKee,A.E., Minet,E., Stern,C., Riahi,S., Stiles,C.D. and
            Silver,P.A.
  TITLE     A genome-wide in situ hybridization map of RNA-binding proteins
            reveals anatomically restricted expression in the developing mouse
            brain
  JOURNAL   BMC Dev Biol 5, 14 (2005)
   PUBMED   16033648
  REMARK    Publication Status: Online-Only
REFERENCE   6  (bases 1 to 1904)
  AUTHORS   Stryke,D., Kawamoto,M., Huang,C.C., Johns,S.J., King,L.A.,
            Harper,C.A., Meng,E.C., Lee,R.E., Yee,A., L'Italien,L.,
            Chuang,P.T., Young,S.G., Skarnes,W.C., Babbitt,P.C. and Ferrin,T.E.
  TITLE     BayGenomics: a resource of insertional mutations in mouse embryonic
            stem cells
  JOURNAL   Nucleic Acids Res 31 (1), 278-281 (2003)
   PUBMED   12520002
REFERENCE   7  (bases 1 to 1904)
  AUTHORS   Zaldumbide,A., Carlotti,F., Pognonec,P. and Boulukos,K.E.
  TITLE     The role of the Ets2 transcription factor in the proliferation,
            maturation, and survival of mouse thymocytes
  JOURNAL   J Immunol 169 (9), 4873-4881 (2002)
   PUBMED   12391198
REFERENCE   8  (bases 1 to 1904)
  AUTHORS   Tamada,H., Sakashita,E., Shimazaki,K., Ueno,E., Hamamoto,T.,
            Kagawa,Y. and Endo,H.
  TITLE     cDNA cloning and characterization of Drb1, a new member of RRM-type
            neural RNA-binding protein
  JOURNAL   Biochem Biophys Res Commun 297 (1), 96-104 (2002)
   PUBMED   12220514
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK140861.1, AK080420.1, CB597326.1 and BB832413.1.
            
            On or before May 4, 2006 this sequence version replaced
            XM_001052100.1, XM_001052101.1, XM_001052102.1, NM_153405.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AY152391.1, AK080420.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-396               AK140861.1         2-397
            397-1324            AK080420.1         371-1298
            1325-1796           CB597326.1         170-641
            1797-1895           AK080420.1         1774-1872
            1896-1904           BB832413.1         453-461
FEATURES             Location/Qualifiers
     source          1..1904
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="2"
                     /map="2 44.94 cM"
     gene            1..1904
                     /gene="Rbm45"
                     /gene_synonym="Drb1; Drbp1; G430095G15Rik"
                     /note="RNA binding motif protein 45"
                     /db_xref="GeneID:241490"
                     /db_xref="MGI:MGI:2387367"
     exon            1..445
                     /gene="Rbm45"
                     /gene_synonym="Drb1; Drbp1; G430095G15Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            446..568
                     /gene="Rbm45"
                     /gene_synonym="Drb1; Drbp1; G430095G15Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            569..695
                     /gene="Rbm45"
                     /gene_synonym="Drb1; Drbp1; G430095G15Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            696..818
                     /gene="Rbm45"
                     /gene_synonym="Drb1; Drbp1; G430095G15Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            819..1004
                     /gene="Rbm45"
                     /gene_synonym="Drb1; Drbp1; G430095G15Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1005..1134
                     /gene="Rbm45"
                     /gene_synonym="Drb1; Drbp1; G430095G15Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1135..1219
                     /gene="Rbm45"
                     /gene_synonym="Drb1; Drbp1; G430095G15Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1220..1383
                     /gene="Rbm45"
                     /gene_synonym="Drb1; Drbp1; G430095G15Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1384..1584
                     /gene="Rbm45"
                     /gene_synonym="Drb1; Drbp1; G430095G15Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1585..1898
                     /gene="Rbm45"
                     /gene_synonym="Drb1; Drbp1; G430095G15Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1873..1878
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Rbm45"
                     /gene_synonym="Drb1; Drbp1; G430095G15Rik"
                     /note="hexamer: AATAAA"
     polyA_site      1898
                     /gene="Rbm45"
                     /gene_synonym="Drb1; Drbp1; G430095G15Rik"
                     /note="major polyA site"
ORIGIN      
        1 ggctctcggc tcttccggaa gcggagctgc ttaccggcgt ggggcgagac ggggagctgc
       61 cgggaagcgg ccgggaagcg gccgagaacc tgccgggtga acagggcctg caggggggct
      121 gcgcctgggt cccgcgtggg gcgccatgga cgacgccggc ggcttgggag gcagcggagg
      181 attccgcccg ggcgtagaca gcctggatga gccgcccaac agccgcattt ttctagtgat
      241 cagcaagcac acatccgaat tggtgctgag ggagcgcttc tcgcccttcg gagacatcca
      301 ggacatctgg gtggtgcgcg acaagcacac taaggagtcc aagggcgtgg ccttcgtcaa
      361 gttcgcgcgc agctcacagg cctgccgggc aatggaggag atgcacggac agtgcctggg
      421 tcccagcgac accaagccca tcaaggtttt cattgcccag tcccgatcat caggaagtca
      481 cagggatgtt gaagatgaag aactcacgag aatctttgtt atgataccaa agtcctatac
      541 agaagaagac ctgcgggaga agttcaaggt gtatggagat atcgagtatt gcagcattat
      601 taagaataaa gtcactggag aaagtaaagg cttgggctac gtgcgctatt taaaaccatc
      661 acaagctgcc caggcaatag aaaactgtga tagaagtttc agagcactct tggctgaacc
      721 taaaaataaa gtgtcggggt ccccagaaca agatgattac agcagcggga ggcaggaggc
      781 tttgggacag gaacccagag caaatctgtt tccctttgtt ggagaacagc aatctgaatt
      841 ttcaactttt gacaagaacg atagcagagg ccaagaagct gtctccaaac gcctgtcggt
      901 ggtgtcgaga gtccccttca cggaagagca gctcttcagc atttttgaca tcgtcccagg
      961 cctggagtat tgtgaggttc cgcgagatcc ttattcaaat tacggtcatg gtgtggttca
     1021 gtattttaac gtagcatcag ctatttatgc aaaatacaaa ctgcatgggt tccagtaccc
     1081 tcctgggaat cggatagtcg tctctttcct ggatgacggg agtaatatga cagaactcat
     1141 caggaaaatg gcgacacaga tggtggcggc ccagctcgcg tcgatggtgt ggagtaccac
     1201 gagtcagcag cagtttctgc aatatggagg aaatgctgcc tcacaggcgc ctcaaatcca
     1261 gacagatgtt gtacttccgt cgtgcaaaaa gaaagcgccg cctgaaactc cagtgaaaga
     1321 aaggctgttt gttgtgttta atccccatcc tttgccacta gacgtgttgg aggatatatt
     1381 ctgccgtttt gggaacctga tcgaggtcta ccttgtgtcg ggaaaaaatg tgggctatgt
     1441 caagtatgcc gatagaaaga gcgccaatga ggccatcaca actctgcacg ggaagattct
     1501 gaatggggtc agacttaagg ttatgctggc agattcccca agagaagaat ccaaaaagag
     1561 gcagagaact tactgagcct taagaacaaa gactaactag tgacataatc ctcagctgac
     1621 tgactgaaaa cctgactgga cgaacccctg tggacagttg acagcttttt tttttttttt
     1681 tttttttttt tttttctatt ttcttacata tccgatagtc ttcacaccat tgcttatctg
     1741 ggatcgctga catgtatttt tgtctgacct taatggaaaa attaatatag tagttgtttc
     1801 ctagaacaaa atgttgttgt gtatagcaga aataaagctt ccttagagaa atatgttgtc
     1861 atgtatggca gaaataaagt tcgctttgca taactaaaaa aaaa
//
