LOCUS       NM_028234               9501 bp    mRNA    linear   ROD 10-FEB-2025
DEFINITION  Mus musculus RNA binding motif protein 33 (Rbm33), mRNA.
ACCESSION   NM_028234 XM_355585 XM_920626
VERSION     NM_028234.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 9501)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 9501)
  AUTHORS   Zhang,Y., Yuan,X., Xu,J. and Gu,H.
  TITLE     CircRBM33 induces endothelial dysfunction by targeting the
            miR-6838-5p/PDCD4 axis affecting blood-brain barrier in mice with
            cerebral ischemia-reperfusion injury
  JOURNAL   Clin Hemorheol Microcirc 85 (4), 355-370 (2023)
   PUBMED   37927249
  REMARK    GeneRIF: CircRBM33 induces endothelial dysfunction by targeting the
            miR-6838-5p/PDCD4 axis affecting blood-brain barrier in mice with
            cerebral ischemia-reperfusion injury.
REFERENCE   3  (bases 1 to 9501)
  AUTHORS   Butterfield,N.C., Curry,K.F., Steinberg,J., Dewhurst,H.,
            Komla-Ebri,D., Mannan,N.S., Adoum,A.T., Leitch,V.D., Logan,J.G.,
            Waung,J.A., Ghirardello,E., Southam,L., Youlten,S.E.,
            Wilkinson,J.M., McAninch,E.A., Vancollie,V.E., Kussy,F.,
            White,J.K., Lelliott,C.J., Adams,D.J., Jacques,R., Bianco,A.C.,
            Boyde,A., Zeggini,E., Croucher,P.I., Williams,G.R. and
            Bassett,J.H.D.
  TITLE     Accelerating functional gene discovery in osteoarthritis
  JOURNAL   Nat Commun 12 (1), 467 (2021)
   PUBMED   33473114
  REMARK    Erratum:[Nat Commun. 2021 May 28;12(1):3302. doi:
            10.1038/s41467-021-23768-8.. PMID: 34050183]
            Publication Status: Online-Only
REFERENCE   4  (bases 1 to 9501)
  AUTHORS   Symmons,O., Pan,L., Remeseiro,S., Aktas,T., Klein,F., Huber,W. and
            Spitz,F.
  TITLE     The Shh Topological Domain Facilitates the Action of Remote
            Enhancers by Reducing the Effects of Genomic Distances
  JOURNAL   Dev Cell 39 (5), 529-543 (2016)
   PUBMED   27867070
REFERENCE   5  (bases 1 to 9501)
  AUTHORS   Anderson,E., Devenney,P.S., Hill,R.E. and Lettice,L.A.
  TITLE     Mapping the Shh long-range regulatory domain
  JOURNAL   Development 141 (20), 3934-3943 (2014)
   PUBMED   25252942
REFERENCE   6  (bases 1 to 9501)
  AUTHORS   Lau,N.C., Seto,A.G., Kim,J., Kuramochi-Miyagawa,S., Nakano,T.,
            Bartel,D.P. and Kingston,R.E.
  TITLE     Characterization of the piRNA complex from rat testes
  JOURNAL   Science 313 (5785), 363-367 (2006)
   PUBMED   16778019
REFERENCE   7  (bases 1 to 9501)
  AUTHORS   Sharov,A.A., Piao,Y., Matoba,R., Dudekula,D.B., Qian,Y.,
            VanBuren,V., Falco,G., Martin,P.R., Stagg,C.A., Bassey,U.C.,
            Wang,Y., Carter,M.G., Hamatani,T., Aiba,K., Akutsu,H., Sharova,L.,
            Tanaka,T.S., Kimber,W.L., Yoshikawa,T., Jaradat,S.A., Pantano,S.,
            Nagaraja,R., Boheler,K.R., Taub,D., Hodes,R.J., Longo,D.L.,
            Schlessinger,D., Keller,J., Klotz,E., Kelsoe,G., Umezawa,A.,
            Vescovi,A.L., Rossant,J., Kunath,T., Hogan,B.L., Curci,A.,
            D'Urso,M., Kelso,J., Hide,W. and Ko,M.S.
  TITLE     Transcriptome analysis of mouse stem cells and early embryos
  JOURNAL   PLoS Biol 1 (3), E74 (2003)
   PUBMED   14691545
REFERENCE   8  (bases 1 to 9501)
  AUTHORS   Stryke,D., Kawamoto,M., Huang,C.C., Johns,S.J., King,L.A.,
            Harper,C.A., Meng,E.C., Lee,R.E., Yee,A., L'Italien,L.,
            Chuang,P.T., Young,S.G., Skarnes,W.C., Babbitt,P.C. and Ferrin,T.E.
  TITLE     BayGenomics: a resource of insertional mutations in mouse embryonic
            stem cells
  JOURNAL   Nucleic Acids Res 31 (1), 278-281 (2003)
   PUBMED   12520002
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BB637766.1,
            AK014289.1, CB528202.1, CN703034.1, AK153360.1 and AC134530.3.
            
            On or before Jul 25, 2007 this sequence version replaced
            XM_920626.2, XM_355585.5.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMN00849374,
                              SAMN00849381 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-53                BB637766.1         14-66
            54-1032             AK014289.1         43-1021
            1033-1579           CB528202.1         12-558
            1580-2015           CN703034.1         182-617
            2016-2558           AK153360.1         112-654
            2559-2609           AC134530.3         89069-89119         c
            2610-4118           AK153360.1         706-2214
            4119-9501           AC134530.3         60938-66320         c
FEATURES             Location/Qualifiers
     source          1..9501
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10090"
                     /chromosome="5"
                     /map="5 14.36 cM"
     gene            1..9501
                     /gene="Rbm33"
                     /gene_synonym="3200001K10Rik; 6430512A10Rik; Prr8"
                     /note="RNA binding motif protein 33"
                     /db_xref="GeneID:381626"
                     /db_xref="MGI:MGI:1919670"
     exon            1..222
                     /gene="Rbm33"
                     /gene_synonym="3200001K10Rik; 6430512A10Rik; Prr8"
                     /inference="alignment:Splign:2.1.0"
     CDS             180..3875
                     /gene="Rbm33"
                     /gene_synonym="3200001K10Rik; 6430512A10Rik; Prr8"
                     /note="proline-rich protein 8; proline rich 8"
                     /codon_start=1
                     /product="RNA-binding protein 33"
                     /protein_id="NP_082510.1"
                     /db_xref="CCDS:CCDS51448.1"
                     /db_xref="GeneID:381626"
                     /db_xref="MGI:MGI:1919670"
                     /translation="MAAALGAGGGAGAGDDDFDQFDKPGAERSWRRRAADEDWDSELE
                     DDLLGEDLLSGKKNQSDLSDEELNDDLLQSDNEEEENFSSQGVTISLNTTSGIVTSFE
                     LSDNTNDQSGEQESEYEQGDDELAYHKPEEQELYTQEYPEEGQYEGHDAELTEDQIEY
                     GDEPEEEQLYSDEVLDIEINEPLDEFTDEEYLQAYGGQQGLQVREDCEAEDDLDEITD
                     SQVASETHEGGMETLELQKDIKEESDEEDDDDEESGRLRFKTERKEGTIIRLSDVTRE
                     RRNIPETLELSAEAKAALLEFEERERQHKQGRYGSRRGGRRGGSLMCRGMGDQRRDNS
                     ERGRMKEHRPALLPTQPSVVAHSPRLIPPPQPQPPPPPPPPPPQQQPIRSLFQQQQLQ
                     PLLPLQHPHHPSPPQGVHMPPQIETPRMMLTPPPVTPQQPKNIHINPHFKGTVVTPVQ
                     VPLLPVPSQPRPAVGPQRFPGPPEFPQHTPGPVPNSFNQPPRLPLQDQWRAPPPPQER
                     DPFFLGVSGEPRFPSHLFLEQRSPPPPPPPPTLLNSSHPVPTQSPLPFTQPGPAFNQQ
                     GQQPVFPRERPVRPALQPPGPVGILHFSQPGSATARPFIPPRQPFLPSPGQPFLPTHA
                     QPNLQGPLHPPLPPPHQPQPQPQQPQQQPQHHQHQPPLQPPLQPPHQPPPQHQPPPQH
                     QPQQHQHHHHLSAPPPPLMPMSQPQFRPHVQTAQPQPSSSRMQCTPHQGLRHNAASQN
                     ISKRPMQQMQPTAPRNSNLRELPIAPSHVLEMSGNRCSSTPVAQVKSIVNTSPPCRAV
                     VSSRSSQGNTDAKAKPLSPEAQPKEEAKPEAEFPDEDEETRLYRLKIEEQKRLREEIL
                     KQKELRRQQQAGARKKELLERLAQQQQQQQQQQHQPQQQQQQPQQIYGSQTSMEQEEL
                     AATPSPTNGNPLLPFPGAQCRQNVKTRLLVKNQDITTASVQPKAVNFVPPGANVQHQG
                     QHLRPLKHLRQLPHKVLQVKPMDMEETPHSPQAARVTSLQGRPQDTKPGVKRTVMHRA
                     NSGGGGDGPHVSSKVRVIKLSGGQGGESDGFSHTEGQPQRLPQPPDMRQQPTRKVTLT
                     KGVPQQPQHLPVGPHMYPAIPPGIKSIQGIHPAKKAIMHGRGRGVAGPMGRGRLMPNK
                     QNLRVVECKPQPCVVSVEGLSSSTTDVQLKSLLMSVGPIQSLQMLPQQRKAIAKFKEP
                     AHALAFQQKFHRHMIDLSHINVALIVE"
     exon            223..301
                     /gene="Rbm33"
                     /gene_synonym="3200001K10Rik; 6430512A10Rik; Prr8"
                     /inference="alignment:Splign:2.1.0"
     exon            302..350
                     /gene="Rbm33"
                     /gene_synonym="3200001K10Rik; 6430512A10Rik; Prr8"
                     /inference="alignment:Splign:2.1.0"
     exon            351..427
                     /gene="Rbm33"
                     /gene_synonym="3200001K10Rik; 6430512A10Rik; Prr8"
                     /inference="alignment:Splign:2.1.0"
     exon            428..740
                     /gene="Rbm33"
                     /gene_synonym="3200001K10Rik; 6430512A10Rik; Prr8"
                     /inference="alignment:Splign:2.1.0"
     exon            741..860
                     /gene="Rbm33"
                     /gene_synonym="3200001K10Rik; 6430512A10Rik; Prr8"
                     /inference="alignment:Splign:2.1.0"
     exon            861..1032
                     /gene="Rbm33"
                     /gene_synonym="3200001K10Rik; 6430512A10Rik; Prr8"
                     /inference="alignment:Splign:2.1.0"
     exon            1033..1241
                     /gene="Rbm33"
                     /gene_synonym="3200001K10Rik; 6430512A10Rik; Prr8"
                     /inference="alignment:Splign:2.1.0"
     exon            1242..1530
                     /gene="Rbm33"
                     /gene_synonym="3200001K10Rik; 6430512A10Rik; Prr8"
                     /inference="alignment:Splign:2.1.0"
     exon            1531..1589
                     /gene="Rbm33"
                     /gene_synonym="3200001K10Rik; 6430512A10Rik; Prr8"
                     /inference="alignment:Splign:2.1.0"
     exon            1590..1722
                     /gene="Rbm33"
                     /gene_synonym="3200001K10Rik; 6430512A10Rik; Prr8"
                     /inference="alignment:Splign:2.1.0"
     exon            1723..2066
                     /gene="Rbm33"
                     /gene_synonym="3200001K10Rik; 6430512A10Rik; Prr8"
                     /inference="alignment:Splign:2.1.0"
     exon            2067..2381
                     /gene="Rbm33"
                     /gene_synonym="3200001K10Rik; 6430512A10Rik; Prr8"
                     /inference="alignment:Splign:2.1.0"
     exon            2382..2669
                     /gene="Rbm33"
                     /gene_synonym="3200001K10Rik; 6430512A10Rik; Prr8"
                     /inference="alignment:Splign:2.1.0"
     exon            2670..3338
                     /gene="Rbm33"
                     /gene_synonym="3200001K10Rik; 6430512A10Rik; Prr8"
                     /inference="alignment:Splign:2.1.0"
     exon            3339..3548
                     /gene="Rbm33"
                     /gene_synonym="3200001K10Rik; 6430512A10Rik; Prr8"
                     /inference="alignment:Splign:2.1.0"
     exon            3549..3737
                     /gene="Rbm33"
                     /gene_synonym="3200001K10Rik; 6430512A10Rik; Prr8"
                     /inference="alignment:Splign:2.1.0"
     exon            3738..3826
                     /gene="Rbm33"
                     /gene_synonym="3200001K10Rik; 6430512A10Rik; Prr8"
                     /inference="alignment:Splign:2.1.0"
     exon            3827..9501
                     /gene="Rbm33"
                     /gene_synonym="3200001K10Rik; 6430512A10Rik; Prr8"
                     /inference="alignment:Splign:2.1.0"
     regulatory      6339..6344
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Rbm33"
                     /gene_synonym="3200001K10Rik; 6430512A10Rik; Prr8"
                     /note="hexamer: CATAAA"
     polyA_site      6364
                     /gene="Rbm33"
                     /gene_synonym="3200001K10Rik; 6430512A10Rik; Prr8"
                     /note="major polyA site"
ORIGIN      
        1 gtagtgttgt tttcttcctg cggaggcgag ggtccgctgc ggaccgcgac gcgcgggcct
       61 cgcctctgct cgctcgcggg cgccggccct cgccgctccc ccgcctcccc ggcccgcacc
      121 agagccgtcg gcctgccagg agctcggggg acggctgaag gccgggcccg gggaccacca
      181 tggcggccgc cctgggcgca ggcggaggag caggcgctgg agatgatgac tttgaccagt
      241 ttgacaagcc tggtgcagaa cggtcctgga gaagaagagc tgctgacgag gactgggaca
      301 gtgaactgga agatgacttg cttggagaag atttactgtc tggcaaaaag aaccagtcgg
      361 atttgtcaga tgaagagctg aatgatgatc tgttacagag tgataacgaa gaggaagaaa
      421 atttcagttc tcagggtgtc accatcagtc tgaataccac ctctggcata gttacatcat
      481 ttgagctgtc tgacaacacc aatgaccaat ccggagaaca ggaatctgag tatgaacaag
      541 gagatgatga gctagcctac cacaaacctg aggaacaaga actgtatact caagagtacc
      601 cagaggaagg acagtatgaa ggccatgatg cagagttgac agaagaccaa atagaatatg
      661 gggatgagcc agaggaggag cagctgtaca gtgatgaagt gctggacatc gaaatcaatg
      721 aacctttaga tgaatttaca gatgaagaat atttgcaggc ttatggtggg caacaagggc
      781 tgcaagtgcg ggaagactgt gaggctgaag atgacttaga tgagattact gattcccagg
      841 ttgcttctga gacccacgag ggaggaatgg aaaccctgga actccagaaa gacataaaag
      901 aagaatcaga tgaagaagat gatgatgatg aagaatctgg acgattacgt tttaaaactg
      961 aaaggaaaga aggaacaatt attaggcttt cagatgtaac tagagagaga aggaacattc
     1021 cagaaacttt ggaactttct gcagaagcca aagctgcatt gctggaattt gaagaaagag
     1081 aacgacagca taaacaggga cgctatggtt cccggcgggg aggaaggcga ggaggttctc
     1141 tgatgtgccg tggaatggga gaccagaggc gagacaacag cgaaagggga aggatgaagg
     1201 agcacaggcc tgccctgctt cctacacagc cgtctgttgt ggctcactct ccaagattaa
     1261 tccctcctcc acagccacag cctcctcctc caccaccacc accaccacct cagcagcagc
     1321 caatcagaag tctgttccag caacagcagc tgcagcctct actcccctta cagcatccgc
     1381 atcacccctc cccaccacag ggagtgcaca tgccccccca gattgagact ccaaggatga
     1441 tgttgacccc tcccccagtg actcctcagc agcccaagaa catccacatc aacccacact
     1501 tcaaggggac agtggtaacc cctgttcaag tgcccttgct gccagttcca agccagccga
     1561 ggcctgccgt gggaccccaa agatttccag gccctccaga atttccacag cacacacctg
     1621 gacctgttcc caacagtttt aaccagccac ctagacttcc tctccaggac cagtggagag
     1681 ccccaccccc acctcaggaa cgagaccctt tcttcttagg agtttcaggt gaaccaagat
     1741 tccccagtca tctttttttg gaacagcgaa gtcctcctcc accgccgcct cctcccacgc
     1801 tcctgaacag cagccatcct gttcctactc agagtccctt accgttcact cagcctggac
     1861 cagcttttaa tcagcaagga cagcagccag tgttccctcg agagaggcct gtaagaccag
     1921 ccctgcagcc cccaggccca gtggggatcc tgcactttag ccagccaggg tcagcaactg
     1981 ccaggccttt cattcctcct agacagccat ttctacccag cccgggacag ccattcctgc
     2041 ctacacatgc acagcctaac cttcagggac ccttgcatcc tccgttgcca ccacctcatc
     2101 aaccacagcc ccagccgcaa cagccccaac agcagcccca gcatcaccag caccagccgc
     2161 cccttcagcc tcccctccag cctccacacc agcctccccc acagcatcag cctccccctc
     2221 agcatcagcc acagcagcac cagcatcatc atcacctttc tgctcctccc cctcctctga
     2281 tgcccatgtc tcagccgcag ttcaggccgc atgtacagac tgcccagcca cagcccagca
     2341 gcagtcggat gcagtgtacc ccacatcagg ggctccggca taatgcagca tctcagaata
     2401 taagcaaacg gcccatgcag cagatgcaac ccactgctcc caggaacagt aatctccgtg
     2461 aactccccat agcaccttca catgttttgg agatgagtgg taaccgatgc tcctctacac
     2521 ctgttgctca ggtgaagtcc attgtcaaca catccccacc ttgtagggct gtggtgtctt
     2581 ccaggagctc acagggcaat actgatgcaa aagccaagcc acttagtcct gaagctcaac
     2641 ctaaggaaga agcaaaacca gaagcagagt ttcctgatga agatgaagag acaaggttat
     2701 atcgcttaaa gatagaggag cagaagcgcc tgagagaaga aatcctgaag cagaaggaac
     2761 tacgaaggca acagcaggct ggtgccagaa agaaggagtt actggaaagg cttgcgcagc
     2821 agcagcagca gcagcagcag cagcagcacc agccgcagca gcagcagcag cagccgcagc
     2881 agatctatgg ctcgcagacc tccatggaac aagaggaact ggcagctaca ccatcaccta
     2941 ccaatggtaa cccattgttg ccctttccag gggcacaatg caggcagaat gtgaaaacca
     3001 gacttcttgt taaaaaccaa gacatcacca ctgctagcgt tcagcccaaa gcggtaaact
     3061 ttgtcccacc tggtgctaac gtgcagcatc aagggcaaca cttgagacca ttgaagcatc
     3121 tgcgacagct gccacacaaa gtccttcagg tcaaacctat ggatatggag gagacccccc
     3181 actccccaca ggccgccaga gtgacatccc ttcagggccg gcctcaggac accaagccag
     3241 gggtgaagag gactgtcatg cacagggcca acagtggagg tggtggagat gggccacatg
     3301 tcagctccaa ggtcagggtg attaagttgt ctggagggca gggaggagag agcgatggct
     3361 tttctcacac agaaggccag ccccagcggc ttccacagcc tccggacatg agacagcagc
     3421 ctacccgcaa ggtgacgctg accaaggggg ttcctcagca gcctcagcac cttcctgtgg
     3481 ggccccacat gtacccggct attcctccag ggattaaaag catccaaggg attcacccag
     3541 ccaagaaggc catcatgcat ggacgaggac gaggagtggc aggtcccatg ggccggggac
     3601 gactaatgcc aaataagcag aaccttcgag tggtggaatg caagccacag ccctgtgtgg
     3661 tgtctgtgga aggtctatcc tcatccacca ctgatgtcca gctgaagagt ctgctgatgt
     3721 ccgtgggccc catccagagt ttacagatgc ttccccagca gcggaaagcc atcgcaaagt
     3781 tcaaggagcc agcccatgca ctagcgtttc aacagaaatt ccacaggcac atgattgatc
     3841 tgtcccacat aaatgtggcc ctgattgtgg agtgatcttg aatggaaata tctgacctca
     3901 tgctgcacac actgtggaat ttcttcaagg aagctgtagg tcggtgcagg atccccagaa
     3961 gtgcaggtct ctccagtctg cagtttgcca acttgtctgc gtgccagcca gccacagggt
     4021 gattccagaa gagagctatt taaactggtg gacatgggat tggagtctgg tgttagattg
     4081 ttttgaattc tgttgtccac aagaactctg ttctcgtgtt cttttgtttc cgagtgctta
     4141 taatgcatgt agaccttgtt cttcgtgatc ctgctatgtg attggtcaca gagttttaga
     4201 ttcaggaaag aatgttacca gctcaaattc cgaggatttt tttttccaca gcaaagaata
     4261 tttgataatg gttgcactta tcttcagtac aggctagaaa agagttctca accaggctta
     4321 actggagtgg tctcagaaag ccatcaacag gctctggtaa aacataggta aaaatgggtg
     4381 attatgattg acactcacct gccctggaaa gccagggtgt gagatgggtg tctgggagtg
     4441 gtgccatgga agtggcgatt ctgcttctta taaatacctc caaagtgcca cctgtttcaa
     4501 cagaaacgct cagattgcta gctaggcaag cactgggcac tccagagcca gtggctctgc
     4561 caccctgcag gcagccctct tggcctagtt ttcctggcat agggtgaggc acagcttgaa
     4621 aggtggtcag acctgcttgg gcttctttgc ttttcaaatg tcctagctct gtagttcgtg
     4681 ctgtcattgg tttgattgtc tcactgtcct tcattcaggg ctctgagttt cctttgggct
     4741 gcctttctat cacatttgtg aaggatggat ttctcagcag ggctgatgct gcccaagata
     4801 agtatatctg tccacattag tcattttagt cgattccaac aggtgagact tgctttctac
     4861 aaagcatccc ttagaagtcc atgctgggca gacattgaac acagtgcctt attatgtttc
     4921 tcccttgaat gcttcagtgt tttgagtcat actctagaat ggactgacac taggacacac
     4981 tcaggacttt tttagttgta ttttatacct gtgattttat ctcacatatc ttggtaggat
     5041 ggaggagaca gaggtctgtt gtcatctact gtcgctgggt aataaggagg gagctctgga
     5101 ctcaaagcag ctggcttcca cagctgaagg ttttacatta cgttttcaat taagttgcca
     5161 acgttttaac aactggagaa tggtattcca ggccccaaga aactttgctt aggattgatt
     5221 ctgagatgac actgtgtgct ggcaaggagc attggggggc acagttgttg tttggtatcc
     5281 aggcagttga gctgaggcat tcataggatg tcttagaaga cattgtggta tggtgccacc
     5341 tctgaccaca cagcctctgc ctcacgcctg cttggtacac taagggccag ccctgcaggg
     5401 gctgtaccca gcttggcctt agcccatcta agtgctgtca actggtctcc cactgtcact
     5461 cccactcatt tcatttggac acaggaaatg ttgatagata tttcgttaaa ttggtgagtt
     5521 tggtaatatg ttagctctca ttggacaaga tagacgccat ataggaggct gagggttagg
     5581 acacagtaaa atgaatttaa cagtttcact gctttctcaa gtagttttga gtgctgggtc
     5641 cttaaaaccc aactatgcat ttttgtctga aagtaggcac tgaagcattg aagtaaggta
     5701 aggagacatc ctcttcgaca ccgctgttga ccgaggagct cagggccact ttgagtgtga
     5761 tgagataccc aggaacacgt gtgcccacag ctgaagtttt acattacgtt ttcaattaag
     5821 ttgccaacat tttaacaact ggcacacaca tgagcctaca cacttgagcc tacacacatg
     5881 agccagtttt tccttattgt agtgtcctgt gagacagacc agctccaagc actgcttaga
     5941 acaacggctc actctgacct tgctacacat ccatttgggg tggactatca gaccaggcaa
     6001 gccagtccta aaggcttctg tgaaggaaac cacagaaagt gaaagaagca gaattagaaa
     6061 gagcattccc cacttgcagt gtccttctca cagggaagtc agacggtgga agatctgctg
     6121 caaccattat ctctgttctt tgtgtatcat gcatttaaaa tgagatggaa aagcattagc
     6181 atactgtgta aatatggacc ttttcagatt aaaacgttaa tggaaatgct tttaactcaa
     6241 acagcaacat cttagctatt tgttagttct cttttgttgt cttatcaaag tttaatggag
     6301 acactttcat aattgttgtt gtgtgtacat ttgattttca taaagatggt agtaagtcaa
     6361 tgcattaacc ctcatctgtg tattatttgt tcacaagttc cagaggttga aggactgact
     6421 ctcacatctg tcctgaggta gagagtaggg gtggggacaa ggtactttcc ctctctctgc
     6481 cttgtttatt ttgtactgta atgaatgtga gtcactcagc tgcttacctg aacataacct
     6541 tatgctgccc ttggcttggc cacatttgtt aaatccttat tatattgata ctcttcttga
     6601 ggaggaaatc tcaccttttc tttttcaaga gattctgagg cagtccccac ccaatccaaa
     6661 taggtagctg cttgtgcagg tcctgtgccc atggcttgct gtggaggagt gtggctgatg
     6721 gcctgggagg tgggttttcc ataatcattt ccatttgcta gttctcatgt gatatgcaac
     6781 ggtccaagat ggttatctga atcaggatag aacacccatt agtcattttc cccccacaaa
     6841 gcagcattct gcctgaagca ggtagaaggc tttgctgctc atggaagctg gtagggaact
     6901 taaaaggcat gggagggagg actggacagt ggtcgctccg gtgggtaagg agagtcttat
     6961 agcatggatt gttagtaatg tacacctctg atgggactcc aaagggtggt ccttcactta
     7021 ggtgtagagc cccacagatg gacatgtgag ggaattcttg gggtgacata aactagataa
     7081 agggcctttc ttggagaact aggcttaagg aatatccctg tcttctgtct tttggttttc
     7141 gtttgttcgt cttttatttt cttgtggcat tattaggcag gtaagcttga tgtagaccat
     7201 tgactgaccc cagtcaaaga taggtcctag tgatataaga acactagccc aaaaggtcta
     7261 tgcagtagtt aagtagtgct tttgcttatt atagggtgct ctgagggtct tctctgtgtc
     7321 ctctgaccca agacaaaatg cacaagtcag gaagcacttc cttgtgcccg agctgtgggc
     7381 caccctgggg gcgctgtcgc tgctgtttcc ctgcccgaga atcagcttga attcccactt
     7441 ctgcttgttg gccccagctc tggctttgca tccttactct catgcccagt tgcttagaga
     7501 gaacgggaga acaggtctaa ggaattgtac cttgatgtgc tctgcaaagg agataacgaa
     7561 tggggcgcag ggtagacaag aacaagaccc ctccccacag aggaagccac taggagctta
     7621 actcaattat gggagaacct tagacacttc accaaattct gcaatgacag ctggggtatt
     7681 ttaaagttta tgatgaagta ttctttttat attcttaaat ataaacttgg aaaggcattt
     7741 agccttgatt tgttaaatcc taaggatttc ctgtaaggtt ttttgcaacc tatttagttt
     7801 ttgtcattta aaatgcctaa cttcttaggt acacaaaccc atggctttgt gtactagaac
     7861 cagagcaatc cactgattca tattggatcc caagtatacc tcctgctggt atcaggtgtc
     7921 agaagggaca tttgttagat gccttacttg accttcctag gaactgttga tcagctacct
     7981 ctttctgtca agtgttggta gaatgggctg aaaagacagg tacttgcacc gaaagagctc
     8041 ttcttttccc cttagatgta cagtaggaga ggttgttaag tgttctctct ttgcttccgt
     8101 ttactgagtt ttcaaaggtt tgtgggaaaa tgtaggtgat ttagagagaa ccttgtgtag
     8161 tttttcttac gactcagaca ggtgggatgg acagacaggt gcatgttact gcgttctgtg
     8221 tcggaaagta tagtatgctc taagcagtag gcctcttgac tttcttacat gactttctgc
     8281 taaactactt ttcattttaa gggcacacgc agcagaggct ggtttggaga ctaacacatt
     8341 ttgcattctg cattgttgtc ttagagcaca cacacgttag acagcgggtt gcagccaccc
     8401 cacactgacc ggccgctgag gagcagataa ccacttgttc tttacttttt acaggtgtgg
     8461 gatcccgatc ctgagctgtg tcctctgtga ggacttccct cccaggcttc aatccagatg
     8521 tttcgtttcc aggtgcagca gcgctgcctt gtgctttcct gtgactttaa gagcatctga
     8581 tgttctgttc tcttctccca ctacgcaacc cactgccctg ccctgccctg ccctggcggg
     8641 gactctggtt ccctccttgc cttctgcttc tcttccatct ggttgacaac acctaaggtg
     8701 ttgtgactgt tcccccaccc agtgcatgtt ctttccctcc atttctgtgg cttccacgtc
     8761 tgcagtggcc actgatactc acttgagtca ggctccctct ggcaggaggg agcactgtgg
     8821 atgtctgcgc cagggccagc cacatgtgca gtttctctga cccttttgcc ttgacaggtc
     8881 tctccttggg atttgctcct ccagaacctg aattggagag cttgaccttt tgcttgttat
     8941 tttgcagttt gattttgggc ctaaagatgc cagtgctttt cagctgtggt gtgcatgtca
     9001 ttaactaccc ctctctgttt ttacccctct acctttgcag gacccgggtc atgggtcagt
     9061 gttagtggta gcgtgctctc attcgcttgg aagtggtggc catgtggccg ttatacagcc
     9121 tttgctgata tggccctcat cgtcgtgtaa tgtttgtgca cctccctgct gtgcaggcag
     9181 cttggagtgc aggctgtgtt gctgggagtg cgctggctgc ttagaaacca cgagacacca
     9241 cctcactttc ctctggcctc actgtttctg ccagtcacat gctcttcctg tatgagtgac
     9301 actgccgtgc tttcctccag ttatcctttg cattaactac gtgggaactc ttgcaggcta
     9361 tatatgtgaa gaatagttgt gatgtagatg gaaagaaaat gtattattgt gtgtatcatt
     9421 tgtgtgcttt catagcaaaa aatgtgtttc agttgtactg taaccaaaaa ttctgtcaat
     9481 aaaatatttg aggttttcct g
//
