LOCUS       NM_001081425            3224 bp    mRNA    linear   ROD 28-AUG-2024
DEFINITION  Mus musculus RNA binding motif protein 24 (Rbm24), mRNA.
ACCESSION   NM_001081425 XM_989409
VERSION     NM_001081425.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3224)
  AUTHORS   Lukomska,A., Rheaume,B.A., Frost,M.P., Theune,W.C., Xing,J.,
            Damania,A. and Trakhtenberg,E.F.
  TITLE     Augmenting fibronectin levels in injured adult CNS promotes axon
            regeneration in vivo
  JOURNAL   Exp Neurol 379, 114877 (2024)
   PUBMED   38944331
REFERENCE   2  (bases 1 to 3224)
  AUTHORS   Wang,K., Liu,X.Y., Liu,S.F., Wang,X.X., Wei,Y.H., Zhu,J.R., Liu,J.,
            Xu,X.Q. and Wen,L.
  TITLE     Rbm24/Notch1 signaling regulates adult neurogenesis in the
            subventricular zone and mediates Parkinson-associated olfactory
            dysfunction
  JOURNAL   Theranostics 14 (11), 4499-4518 (2024)
   PUBMED   39113792
  REMARK    GeneRIF: Rbm24/Notch1 signaling regulates adult neurogenesis in the
            subventricular zone and mediates Parkinson-associated olfactory
            dysfunction.
            Publication Status: Online-Only
REFERENCE   3  (bases 1 to 3224)
  AUTHORS   Wang,G., Gu,Y. and Liu,Z.
  TITLE     Deciphering the genetic interactions between Pou4f3, Gfi1, and
            Rbm24 in maintaining mouse cochlear hair cell survival
  JOURNAL   Elife 12, 90025 (2024)
   PUBMED   38483314
  REMARK    GeneRIF: Deciphering the genetic interactions between Pou4f3, Gfi1,
            and Rbm24 in maintaining mouse cochlear hair cell survival.
            Publication Status: Online-Only
REFERENCE   4  (bases 1 to 3224)
  AUTHORS   Wang,Y., Zhang,C., Peng,W., Du,H., Xi,Y. and Xu,Z.
  TITLE     RBM24 is required for mouse hair cell development through
            regulating pre-mRNA alternative splicing and mRNA stability
  JOURNAL   J Cell Physiol 238 (5), 1095-1110 (2023)
   PUBMED   36947695
  REMARK    GeneRIF: RBM24 is required for mouse hair cell development through
            regulating pre-mRNA alternative splicing and mRNA stability.
REFERENCE   5  (bases 1 to 3224)
  AUTHORS   Zhang,J., Kong,X., Sun,W., Wang,L., Shen,T., Chen,M. and Chen,X.
  TITLE     The RNA-binding protein RBM24 regulates lipid metabolism and
            SLC7A11 mRNA stability to modulate ferroptosis and inflammatory
            response
  JOURNAL   Front Cell Dev Biol 10, 1008576 (2022)
   PUBMED   36478739
  REMARK    Publication Status: Online-Only
REFERENCE   6  (bases 1 to 3224)
  AUTHORS   Xu,E., Zhang,J., Zhang,M., Jiang,Y., Cho,S.J. and Chen,X.
  TITLE     RNA-binding protein RBM24 regulates p63 expression via mRNA
            stability
  JOURNAL   Mol Cancer Res 12 (3), 359-369 (2014)
   PUBMED   24375645
  REMARK    GeneRIF: Study suggests that p63 is regulated by RBM24 via mRNA
            stability, which gives an insight into understanding how
            posttranscriptional regulatory mechanisms contribute to p63
            expression.
REFERENCE   7  (bases 1 to 3224)
  AUTHORS   Lachke,S.A., Ho,J.W., Kryukov,G.V., O'Connell,D.J., Aboukhalil,A.,
            Bulyk,M.L., Park,P.J. and Maas,R.L.
  TITLE     iSyTE: integrated Systems Tool for Eye gene discovery
  JOURNAL   Invest Ophthalmol Vis Sci 53 (3), 1617-1627 (2012)
   PUBMED   22323457
  REMARK    Publication Status: Online-Only
REFERENCE   8  (bases 1 to 3224)
  AUTHORS   Jin,D., Hidaka,K., Shirai,M. and Morisaki,T.
  TITLE     RNA-binding motif protein 24 regulates myogenin expression and
            promotes myogenic differentiation
  JOURNAL   Genes Cells 15 (11), 1158-1167 (2010)
   PUBMED   20977548
  REMARK    GeneRIF: Rbm24 plays a crucial role in myogenic differentiation at
            least in part through a myogenin-dependent post-transcriptional
            regulatory pathway.
REFERENCE   9  (bases 1 to 3224)
  AUTHORS   Xu,X.Q., Soo,S.Y., Sun,W. and Zweigerdt,R.
  TITLE     Global expression profile of highly enriched cardiomyocytes derived
            from human embryonic stem cells
  JOURNAL   Stem Cells 27 (9), 2163-2174 (2009)
   PUBMED   19658189
REFERENCE   10 (bases 1 to 3224)
  AUTHORS   Tamplin,O.J., Kinzel,D., Cox,B.J., Bell,C.E., Rossant,J. and
            Lickert,H.
  TITLE     Microarray analysis of Foxa2 mutant mouse embryos reveals novel
            gene expression and inductive roles for the gastrula organizer and
            its derivatives
  JOURNAL   BMC Genomics 9, 511 (2008)
   PUBMED   18973680
  REMARK    Publication Status: Online-Only
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AC124411.5.
            
            On Feb 6, 2007 this sequence version replaced XM_989409.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR1660813.151711.1,
                                           SRR1660825.42772.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-899               AC124411.5         37935-38833         c
            900-1023            AC124411.5         36735-36858         c
            1024-1078           AC124411.5         35228-35282         c
            1079-3224           AC124411.5         26034-28179         c
FEATURES             Location/Qualifiers
     source          1..3224
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10090"
                     /chromosome="13"
                     /map="13 23.61 cM"
     gene            1..3224
                     /gene="Rbm24"
                     /gene_synonym="6330546B05Rik"
                     /note="RNA binding motif protein 24"
                     /db_xref="GeneID:666794"
                     /db_xref="MGI:MGI:3610364"
     exon            1..899
                     /gene="Rbm24"
                     /gene_synonym="6330546B05Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             732..1442
                     /gene="Rbm24"
                     /gene_synonym="6330546B05Rik"
                     /codon_start=1
                     /product="RNA-binding protein 24"
                     /protein_id="NP_001074894.1"
                     /db_xref="CCDS:CCDS36651.1"
                     /db_xref="GeneID:666794"
                     /db_xref="MGI:MGI:3610364"
                     /translation="MHTTQKDTTYTKIFVGGLPYHTTDASLRKYFEVFGDIEEAVVIT
                     DRQTGKSRGYGFVTMADRAAAERACKDPNPIIDGRKANVNLAYLGAKPRIMQPGFAFG
                     VQQLHPALIQRPFGIPAHYVYPQAFVQPGVVIPHVQPTAAAASTTPYIDYTGAAYAQY
                     SAAAAAAAAAAAYDQYPYAASPAAAGYVTTGGYSYAVQQPITAAAPGTAAAAAAAAAA
                     AAAFGQYQPQQLQTDRMQ"
     exon            900..1023
                     /gene="Rbm24"
                     /gene_synonym="6330546B05Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1024..1078
                     /gene="Rbm24"
                     /gene_synonym="6330546B05Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1079..3224
                     /gene="Rbm24"
                     /gene_synonym="6330546B05Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2671..2676
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Rbm24"
                     /gene_synonym="6330546B05Rik"
                     /note="hexamer: ATTAAA"
     polyA_site      2696
                     /gene="Rbm24"
                     /gene_synonym="6330546B05Rik"
     regulatory      3204..3209
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Rbm24"
                     /gene_synonym="6330546B05Rik"
                     /note="hexamer: AATATA"
     polyA_site      3220
                     /gene="Rbm24"
                     /gene_synonym="6330546B05Rik"
                     /note="major polyA site"
ORIGIN      
        1 agagccccag ccaggcgacc cagcgcccgc gcgcggggag agaagcagct gttcccaaca
       61 gctggggggc ggcggcgccg ggcgccccag gtgctgtccc ggccaatcgc aggcgtccgg
      121 cccgccccct ccccagccgg gcgtcgaccc ccagggccgc tggggaaaaa ggaatagagg
      181 gttggagagc ggtcctccgt ccgcactggt gtggcagcta ctaagcagaa gggacggttc
      241 ccagaccgag ccgggcccag caccgcgccc ccagctgcca cctccgcgcc cccgggacac
      301 ggtagcctct gagccaaccc ccatcccact aagccactcg attttttgag aaagaaccat
      361 ctacctcttc tggacttgga gaccaccacc ctctctgcat ttaagaaaaa aaatattttt
      421 attttatttt tactttcacg cggcgtgagt gcaaaaggct cccacagtcc gcggctacgg
      481 agctggttac ccggacgatc cggaaggtct ggacagtgac cggacgcggg gactggagca
      541 gagcgcctgg gcgagtgtcg gggacagtgg gccacttggg aagccgcgcg cccagcgccc
      601 acgccgcccc ctcgcccccg cgcgcgccct cggcccccgg cggccgccgc gcgctgcggg
      661 agacgcggag cccgaggacc aggcgcagcc gcagccgcag ccggagcccg agccgcgggg
      721 cgggcgcgaa gatgcacacc acccagaagg acacgacgta caccaagatc ttcgtgggag
      781 ggctgcccta ccacaccacc gacgccagcc tgcgcaagta ctttgaggtc ttcggagaca
      841 tcgaggaagc ggtggtcatc acagaccggc agaccggcaa gtcccggggc tacggatttg
      901 tcaccatggc tgacagggct gccgctgaaa gggcctgcaa ggatcccaac cccatcatcg
      961 atggtaggaa ggccaatgtg aatctggcat acttgggagc aaaaccaaga atcatgcagc
     1021 caggttttgc ctttggcgtt caacagcttc acccagccct tatccagaga cctttcggga
     1081 tccccgccca ctacgtctac ccgcaggctt ttgtgcagcc tggagtggtc attccccatg
     1141 tgcagcccac agcagccgcg gcttccacca caccgtacat tgattacact ggagccgcct
     1201 acgctcagta ctccgctgcc gcagccgccg ccgcagcggc cgctgcctat gaccagtacc
     1261 cctatgcagc atccccagct gctgcaggct atgtaaccac tgggggctac agctatgctg
     1321 tccaacagcc catcaccgcc gctgcgcccg ggacagctgc tgctgcggct gcagctgctg
     1381 cagccgcagc cgcctttggc cagtaccagc ctcaacagct gcagacagac cgaatgcagt
     1441 agaccagctg tctgatcaaa gtcaaaaggg tttctctttt cctcctgatc tcccagtttt
     1501 ttagtagcta atgagaaagt taacagttga cctgccggct ttaaagggag aaggcaaggc
     1561 tagtgtgaag cagaggtgtt actttttacc atactcccgg tagtgctaca ggtgataagg
     1621 ggagaaaggg agggcgagaa acagtttttg aagtcaatcc caaagagccc gagttacaca
     1681 gaatagccac taggagatga tggcaggggt accaatggga cttcactttt gtatggggat
     1741 ttttattttt tgctcttttt ttatagtatc agggaagcaa actgcctttt ccaagttaga
     1801 aaatgctatg tgaatctagt tgaaccaggg aatacggagt gagcaatatg tagcttgaat
     1861 tacgcgtaaa agtagattta aaaagaaaag aaaagaaaac aagacagaaa agcgctggtt
     1921 gtccttcgtt gcagtaacgg caggcctgca gaactttgtt gaggcaggag gtagtgtgtt
     1981 tgtgctatct cagaagatgg gcatcgaaca atcagtttcg gggtgtgacg gcggggacgg
     2041 tggtggacag gtaccaaagc tattttctca tctgtcctgt ggacgagtgg ggttgtggag
     2101 ccattgatac tgcaccagcc gctcagacaa tcaacagcac acactgttca agaaagagtc
     2161 catcacttgt actcgtggga ggagcttgtc ccattataac tcctctcccc attccctgtc
     2221 acttggggat gatttcatct gcgggtcagg ctttcaccac accacttgtc tttctattta
     2281 ttacatagac tagaggatta tgggtaaagg caggcagaag ttgcagatgc tcgccccttc
     2341 gggactgtct gaaggacctt tcttttcctc ctgccccacc cctccccctt taaaataatt
     2401 tgacacgttt ttcgtatcta tttcagagtc ctatttaaaa ctatttatta gtgactacag
     2461 tacctaagac agcaaggttc ttgacattac agttctccga cagttgatga tcttgtactt
     2521 tataatgtgc cttaataata atcctattta agatatttat ttttaagttt tactatgctg
     2581 cactctaaag gaaggaactt tagaagtgac actgtaaaat tatgtattca tctcatggca
     2641 taagttattc agtaggtcta gatgtagcat attaaatatt aacctattca actaaagacg
     2701 ttggctttgg atttatttaa attcatatgt gcactgttcg ggtgggtact cttgcctaaa
     2761 catatttgag tttattttag tcttgagttg ttttactttt tttttttttt taaacaagct
     2821 acatcgctgg ttctgtgctt cctcaattgc tttccccctg tggatctcat gtaccgggga
     2881 ctcatggcat ccccgctttc ctcgtgtagt gtatgtagtt ttaaaagacg gctttatatt
     2941 tttccttctg aaagtgagat acttgcaatt tttactctta aactaaaatg aatactattt
     3001 tacactgtat tggactttta tacttgaaga acttcctaca atggataatt tttatggact
     3061 ctctccattg tcactggatt taagtattcc tgtgccgggc agtggtccgc aaaggagggc
     3121 gtggctctcc tgtgcaaatt atttatttgt tgtgtatttc gctttataat gtttcagatc
     3181 ttctcatcta ttcacttgta ttaaatataa tttttaaaaa ctgc
//
