LOCUS       NP_001074894             236 aa            linear   ROD 27-APR-2025
DEFINITION  RNA-binding protein 24 [Mus musculus].
ACCESSION   NP_001074894 XP_994503
VERSION     NP_001074894.1
DBSOURCE    REFSEQ: accession NM_001081425.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (residues 1 to 236)
  AUTHORS   Lukomska,A., Rheaume,B.A., Frost,M.P., Theune,W.C., Xing,J.,
            Damania,A. and Trakhtenberg,E.F.
  TITLE     Augmenting fibronectin levels in injured adult CNS promotes axon
            regeneration in vivo
  JOURNAL   Exp Neurol 379, 114877 (2024)
   PUBMED   38944331
REFERENCE   2  (residues 1 to 236)
  AUTHORS   Wang,K., Liu,X.Y., Liu,S.F., Wang,X.X., Wei,Y.H., Zhu,J.R., Liu,J.,
            Xu,X.Q. and Wen,L.
  TITLE     Rbm24/Notch1 signaling regulates adult neurogenesis in the
            subventricular zone and mediates Parkinson-associated olfactory
            dysfunction
  JOURNAL   Theranostics 14 (11), 4499-4518 (2024)
   PUBMED   39113792
  REMARK    GeneRIF: Rbm24/Notch1 signaling regulates adult neurogenesis in the
            subventricular zone and mediates Parkinson-associated olfactory
            dysfunction.
            Publication Status: Online-Only
REFERENCE   3  (residues 1 to 236)
  AUTHORS   Wang,G., Gu,Y. and Liu,Z.
  TITLE     Deciphering the genetic interactions between Pou4f3, Gfi1, and
            Rbm24 in maintaining mouse cochlear hair cell survival
  JOURNAL   Elife 12, 90025 (2024)
   PUBMED   38483314
  REMARK    GeneRIF: Deciphering the genetic interactions between Pou4f3, Gfi1,
            and Rbm24 in maintaining mouse cochlear hair cell survival.
            Publication Status: Online-Only
REFERENCE   4  (residues 1 to 236)
  AUTHORS   Wang,Y., Zhang,C., Peng,W., Du,H., Xi,Y. and Xu,Z.
  TITLE     RBM24 is required for mouse hair cell development through
            regulating pre-mRNA alternative splicing and mRNA stability
  JOURNAL   J Cell Physiol 238 (5), 1095-1110 (2023)
   PUBMED   36947695
  REMARK    GeneRIF: RBM24 is required for mouse hair cell development through
            regulating pre-mRNA alternative splicing and mRNA stability.
REFERENCE   5  (residues 1 to 236)
  AUTHORS   Zhang,J., Kong,X., Sun,W., Wang,L., Shen,T., Chen,M. and Chen,X.
  TITLE     The RNA-binding protein RBM24 regulates lipid metabolism and
            SLC7A11 mRNA stability to modulate ferroptosis and inflammatory
            response
  JOURNAL   Front Cell Dev Biol 10, 1008576 (2022)
   PUBMED   36478739
  REMARK    Publication Status: Online-Only
REFERENCE   6  (residues 1 to 236)
  AUTHORS   Xu,E., Zhang,J., Zhang,M., Jiang,Y., Cho,S.J. and Chen,X.
  TITLE     RNA-binding protein RBM24 regulates p63 expression via mRNA
            stability
  JOURNAL   Mol Cancer Res 12 (3), 359-369 (2014)
   PUBMED   24375645
  REMARK    GeneRIF: Study suggests that p63 is regulated by RBM24 via mRNA
            stability, which gives an insight into understanding how
            posttranscriptional regulatory mechanisms contribute to p63
            expression.
REFERENCE   7  (residues 1 to 236)
  AUTHORS   Lachke,S.A., Ho,J.W., Kryukov,G.V., O'Connell,D.J., Aboukhalil,A.,
            Bulyk,M.L., Park,P.J. and Maas,R.L.
  TITLE     iSyTE: integrated Systems Tool for Eye gene discovery
  JOURNAL   Invest Ophthalmol Vis Sci 53 (3), 1617-1627 (2012)
   PUBMED   22323457
  REMARK    Publication Status: Online-Only
REFERENCE   8  (residues 1 to 236)
  AUTHORS   Jin,D., Hidaka,K., Shirai,M. and Morisaki,T.
  TITLE     RNA-binding motif protein 24 regulates myogenin expression and
            promotes myogenic differentiation
  JOURNAL   Genes Cells 15 (11), 1158-1167 (2010)
   PUBMED   20977548
  REMARK    GeneRIF: Rbm24 plays a crucial role in myogenic differentiation at
            least in part through a myogenin-dependent post-transcriptional
            regulatory pathway.
REFERENCE   9  (residues 1 to 236)
  AUTHORS   Xu,X.Q., Soo,S.Y., Sun,W. and Zweigerdt,R.
  TITLE     Global expression profile of highly enriched cardiomyocytes derived
            from human embryonic stem cells
  JOURNAL   Stem Cells 27 (9), 2163-2174 (2009)
   PUBMED   19658189
REFERENCE   10 (residues 1 to 236)
  AUTHORS   Tamplin,O.J., Kinzel,D., Cox,B.J., Bell,C.E., Rossant,J. and
            Lickert,H.
  TITLE     Microarray analysis of Foxa2 mutant mouse embryos reveals novel
            gene expression and inductive roles for the gastrula organizer and
            its derivatives
  JOURNAL   BMC Genomics 9, 511 (2008)
   PUBMED   18973680
  REMARK    Publication Status: Online-Only
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AC124411.5.
            
            On Feb 6, 2007 this sequence version replaced XP_994503.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR1660813.151711.1,
                                           SRR1660825.42772.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..236
                     /organism="Mus musculus"
                     /db_xref="taxon:10090"
                     /chromosome="13"
                     /map="13 23.61 cM"
     Protein         1..236
                     /product="RNA-binding protein 24"
                     /calculated_mol_wt=24691
     Region          11..86
                     /region_name="RRM_RBM24_RBM38_like"
                     /note="RNA recognition motif (RRM) found in eukaryotic
                     RNA-binding protein RBM24, RBM38 and similar proteins;
                     cd12384"
                     /db_xref="CDD:409818"
     Region          175..199
                     /region_name="Necessary for interaction with EIF4E.
                     /evidence=ECO:0000250|UniProtKB:Q9BX46"
                     /note="propagated from UniProtKB/Swiss-Prot (D3Z4I3.1)"
     CDS             1..236
                     /gene="Rbm24"
                     /gene_synonym="6330546B05Rik"
                     /coded_by="NM_001081425.1:732..1442"
                     /db_xref="CCDS:CCDS36651.1"
                     /db_xref="GeneID:666794"
                     /db_xref="MGI:MGI:3610364"
ORIGIN      
        1 mhttqkdtty tkifvgglpy httdaslrky fevfgdieea vvitdrqtgk srgygfvtma
       61 draaaerack dpnpiidgrk anvnlaylga kprimqpgfa fgvqqlhpal iqrpfgipah
      121 yvypqafvqp gvviphvqpt aaaasttpyi dytgaayaqy saaaaaaaaa aaydqypyaa
      181 spaaagyvtt ggysyavqqp itaaapgtaa aaaaaaaaaa afgqyqpqql qtdrmq
//
