LOCUS       NP_080052                420 aa            linear   ROD 27-APR-2025
DEFINITION  pre-mRNA-splicing factor RBM22 [Mus musculus].
ACCESSION   NP_080052 XP_619541 XP_906754 XP_920161 XP_999664 XP_999685
VERSION     NP_080052.1
DBSOURCE    REFSEQ: accession NM_025776.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (residues 1 to 420)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (residues 1 to 420)
  AUTHORS   Koscielny,G., Yaikhom,G., Iyer,V., Meehan,T.F., Morgan,H.,
            Atienza-Herrero,J., Blake,A., Chen,C.K., Easty,R., Di Fenza,A.,
            Fiegel,T., Grifiths,M., Horne,A., Karp,N.A., Kurbatova,N.,
            Mason,J.C., Matthews,P., Oakley,D.J., Qazi,A., Regnart,J.,
            Retha,A., Santos,L.A., Sneddon,D.J., Warren,J., Westerberg,H.,
            Wilson,R.J., Melvin,D.G., Smedley,D., Brown,S.D., Flicek,P.,
            Skarnes,W.C., Mallon,A.M. and Parkinson,H.
  TITLE     The International Mouse Phenotyping Consortium Web Portal, a
            unified point of access for knockout mice and related phenotyping
            data
  JOURNAL   Nucleic Acids Res 42 (Database issue), D802-D809 (2014)
   PUBMED   24194600
REFERENCE   3  (residues 1 to 420)
  AUTHORS   Wiese,C.B., Ireland,S., Fleming,N.L., Yu,J., Valerius,M.T.,
            Georgas,K., Chiu,H.S., Brennan,J., Armstrong,J., Little,M.H.,
            McMahon,A.P. and Southard-Smith,E.M.
  TITLE     A genome-wide screen to identify transcription factors expressed in
            pelvic Ganglia of the lower urinary tract
  JOURNAL   Front Neurosci 6, 130 (2012)
   PUBMED   22988430
  REMARK    Publication Status: Online-Only
REFERENCE   4  (residues 1 to 420)
  AUTHORS   Dequeant,M.L., Glynn,E., Gaudenz,K., Wahl,M., Chen,J., Mushegian,A.
            and Pourquie,O.
  TITLE     A complex oscillating network of signaling genes underlies the
            mouse segmentation clock
  JOURNAL   Science 314 (5805), 1595-1598 (2006)
   PUBMED   17095659
REFERENCE   5  (residues 1 to 420)
  AUTHORS   McKee,A.E., Minet,E., Stern,C., Riahi,S., Stiles,C.D. and
            Silver,P.A.
  TITLE     A genome-wide in situ hybridization map of RNA-binding proteins
            reveals anatomically restricted expression in the developing mouse
            brain
  JOURNAL   BMC Dev Biol 5, 14 (2005)
   PUBMED   16033648
  REMARK    Publication Status: Online-Only
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AK168919.1.
            
            On or before Jul 24, 2006 this sequence version replaced
            XP_619541.1, XP_906754.1, XP_920161.2, XP_999685.1, XP_999664.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK168919.1, AK018452.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..420
                     /organism="Mus musculus"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="18"
                     /map="18 34.36 cM"
     Protein         1..420
                     /product="pre-mRNA-splicing factor RBM22"
                     /calculated_mol_wt=46765
     Site            2
                     /site_type="acetylation"
                     /note="N-acetylalanine.
                     /evidence=ECO:0000250|UniProtKB:Q9NW64; propagated from
                     UniProtKB/Swiss-Prot (Q8BHS3.1)"
     Site            4
                     /site_type="phosphorylation"
                     /note="Phosphoserine.
                     /evidence=ECO:0000250|UniProtKB:Q9NW64; propagated from
                     UniProtKB/Swiss-Prot (Q8BHS3.1)"
     Site            102
                     /site_type="phosphorylation"
                     /note="Phosphoserine.
                     /evidence=ECO:0000250|UniProtKB:Q9NW64; propagated from
                     UniProtKB/Swiss-Prot (Q8BHS3.1)"
     Region          159..185
                     /region_name="ZnF_C3H1"
                     /note="zinc finger; smart00356"
                     /db_xref="CDD:214632"
     Site            212
                     /site_type="acetylation"
                     /note="N6-acetyllysine.
                     /evidence=ECO:0007744|PubMed:23806337; propagated from
                     UniProtKB/Swiss-Prot (Q8BHS3.1)"
     Region          231..304
                     /region_name="RRM_RBM22"
                     /note="RNA recognition motif (RRM) found in
                     Pre-mRNA-splicing factor RBM22 and similar proteins;
                     cd12224"
                     /db_xref="CDD:409671"
     Region          303..343
                     /region_name="Disordered.
                     /evidence=ECO:0000256|SAM:MobiDB-lite"
                     /note="propagated from UniProtKB/Swiss-Prot (Q8BHS3.1)"
     Region          372..420
                     /region_name="Disordered.
                     /evidence=ECO:0000256|SAM:MobiDB-lite"
                     /note="propagated from UniProtKB/Swiss-Prot (Q8BHS3.1)"
     CDS             1..420
                     /gene="Rbm22"
                     /gene_synonym="8430430L24Rik"
                     /coded_by="NM_025776.2:41..1303"
                     /db_xref="CCDS:CCDS29272.1"
                     /db_xref="GeneID:66810"
                     /db_xref="MGI:MGI:1914060"
ORIGIN      
        1 matslgsnty nrqnwedadf pilcqtclge npyirmtkek ygkeckicar pftvfrwcpg
       61 vrmrfkktev cqtcsklknv cqtclldley glpiqvrdag lsfkddmpks dvnkeyytqn
      121 mereisnsdg trpvgmlgka tstsdmllkl arttpyykrn rphicsfwvk geckrgeecp
      181 yrhekptdpd dpladqnikd ryygindpva dkllkrastm prldppedkt ittlyvgglg
      241 dtitetdlrn hfyqfgeirt itvvqrqqca fiqfatrqaa evaaeksfnk livngrrlnv
      301 kwgrsqaarg kekekdgttd sgiklepvpg lpgalppppa aeeeasanyf nlppsgppav
      361 vnialppppg iapppppgfg phmfhpmgpp ppfmrapgpi hypsqdpqrm gahagkhssp
//
