LOCUS       NM_029397               6640 bp    mRNA    linear   ROD 24-DEC-2024
DEFINITION  Mus musculus RNA binding motif protein 12 (Rbm12), transcript
            variant 1, mRNA.
ACCESSION   NM_029397
VERSION     NM_029397.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 6640)
  AUTHORS   Bedogni,F. and Hevner,R.F.
  TITLE     Cell-Type-Specific Gene Expression in Developing Mouse Neocortex:
            Intermediate Progenitors Implicated in Axon Development
  JOURNAL   Front Mol Neurosci 14, 686034 (2021)
   PUBMED   34321999
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6640)
  AUTHORS   Sun,M., Mondal,K., Patel,V., Horner,V.L., Long,A.B., Cutler,D.J.,
            Caspary,T. and Zwick,M.E.
  TITLE     Multiplex Chromosomal Exome Sequencing Accelerates Identification
            of ENU-Induced Mutations in the Mouse
  JOURNAL   G3 (Bethesda) 2 (1), 143-150 (2012)
   PUBMED   22384391
REFERENCE   3  (bases 1 to 6640)
  AUTHORS   McKee,A.E., Minet,E., Stern,C., Riahi,S., Stiles,C.D. and
            Silver,P.A.
  TITLE     A genome-wide in situ hybridization map of RNA-binding proteins
            reveals anatomically restricted expression in the developing mouse
            brain
  JOURNAL   BMC Dev Biol 5, 14 (2005)
   PUBMED   16033648
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 6640)
  AUTHORS   Jerez-Timaure,N.C., Eisen,E.J. and Pomp,D.
  TITLE     Fine mapping of a QTL region with large effects on growth and
            fatness on mouse chromosome 2
  JOURNAL   Physiol Genomics 21 (3), 411-422 (2005)
   PUBMED   15769905
REFERENCE   5  (bases 1 to 6640)
  AUTHORS   Okazaki,N., Kikuno,R., Ohara,R., Inamoto,S., Koseki,H., Hiraoka,S.,
            Saga,Y., Nagase,T., Ohara,O. and Koga,H.
  TITLE     Prediction of the coding sequences of mouse homologues of KIAA
            gene: III. the complete nucleotide sequences of 500 mouse
            KIAA-homologous cDNAs identified by screening of terminal sequences
            of cDNA clones randomly sampled from size-fractionated libraries
  JOURNAL   DNA Res 10 (4), 167-180 (2003)
   PUBMED   14621295
REFERENCE   6  (bases 1 to 6640)
  AUTHORS   Ehringer,M.A., Thompson,J., Conroy,O., Xu,Y., Yang,F., Canniff,J.,
            Beeson,M., Gordon,L., Bennett,B., Johnson,T.E. and Sikela,J.M.
  TITLE     High-throughput sequence identification of gene coding variants
            within alcohol-related QTLs
  JOURNAL   Mamm Genome 12 (8), 657-663 (2001)
   PUBMED   11471062
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL833786.8.
            
            On Jul 8, 2022 this sequence version replaced NM_029397.3.
            
            Summary: This gene encodes a protein that contains several
            RNA-binding motifs, potential transmembrane domains, and
            proline-rich regions. This gene and the gene for copine I overlap
            at map location 2 H2. Two alternatively spliced transcript variants
            have been identified for this gene. Both variants encode the same
            protein. [provided by RefSeq, Jul 2008].
            
            Transcript Variant: This variant (1) is the longer transcript.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC052473.1, AK035014.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849383, SAMN02415130
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-142               AL833786.8         162498-162639       c
            143-223             AL833786.8         154061-154141       c
            224-6640            AL833786.8         142668-149084       c
FEATURES             Location/Qualifiers
     source          1..6640
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="2"
                     /map="2 77.35 cM"
     gene            1..6640
                     /gene="Rbm12"
                     /gene_synonym="5730420G12Rik; 9430070C08Rik; mKIAA0765;
                     SWAN"
                     /note="RNA binding motif protein 12"
                     /db_xref="GeneID:75710"
                     /db_xref="MGI:MGI:1922960"
     exon            1..142
                     /gene="Rbm12"
                     /gene_synonym="5730420G12Rik; 9430070C08Rik; mKIAA0765;
                     SWAN"
                     /inference="alignment:Splign:2.1.0"
     exon            143..223
                     /gene="Rbm12"
                     /gene_synonym="5730420G12Rik; 9430070C08Rik; mKIAA0765;
                     SWAN"
                     /inference="alignment:Splign:2.1.0"
     exon            224..6640
                     /gene="Rbm12"
                     /gene_synonym="5730420G12Rik; 9430070C08Rik; mKIAA0765;
                     SWAN"
                     /inference="alignment:Splign:2.1.0"
     CDS             246..3224
                     /gene="Rbm12"
                     /gene_synonym="5730420G12Rik; 9430070C08Rik; mKIAA0765;
                     SWAN"
                     /note="SH3/WW domain anchor protein in the nucleus"
                     /codon_start=1
                     /product="RNA-binding protein 12"
                     /protein_id="NP_083673.3"
                     /db_xref="CCDS:CCDS16961.1"
                     /db_xref="GeneID:75710"
                     /db_xref="MGI:MGI:1922960"
                     /translation="MAVVIRLQGLPIVAGTMDIRHFFSGLTIPDGGVHIVGGELGEAF
                     IVFATDEDARLGMMRTGGTIKGSKVTLLLSSKTEMQNMIELSRRRFETANLDIPPANA
                     SRSGPPPSSGMSSRVNLPAIVPNFNNPSPSVVTATTSVHESNKNIQTFSTASVGTAPP
                     SMGTSFGSPTFSSTIPSTASPMNTVPPPPIPPIPAMPSLPPLPSIPPIPVPPPVPTLP
                     PVPPVPPIPPVPSVPPMTTLPPMSGMPPLNPPPVAPLPAGMNGSGAPIGLNNNMNPVF
                     LGPLNPVNSIQMNSQSSVKSLPINPDDLYVSVHGMPFSAMENDVREFFHGLRVDAVHL
                     LKDHVGRNNGNGLVKFLSPQDTFEALKRNRMLMIQRYVEVSPATERQWVAAGGHITFK
                     QSMGPSGQAHPPPQTLPRSKSPSGQKRSRSRSPHEAGFCVYLKGLPFEAENKHVIDFF
                     KKLDIVEDSIYIAYGPNGKATGEGFVEFRNDADYKAALCRHKQYMGNRFIQVHPITKK
                     GMLEKIDMIRKRLQNFSYDQRELVLNPEGEVSSAKVCAHITNIPFSITKMDVLQFLEG
                     IPVDESAVHVLVDNNGQGLGQALVQFKTEDDAHKSEHLHRKKLNGREAFVHIVTLEDM
                     REIEKNPPAQGKKGLKISVPGNPAVPVIPSAGMPAAGIPTAGIPGAGLPSAGMPGAGM
                     PSSGMPGPGMPGPGIPGAGIPGPAMPGPAMPGPAMPGPAMPGPAMPGPAMPGPAMPGP
                     AMPGPAIPGPAIPGPAIPGAGIPSAGGEEHVFLTVGSKEANNGPPFNFPGNFGGPNAF
                     GPPLPPPGLGGAFGDVRPVMPSVGNSGLPGLGLEVPGFGGAPNNISGPSGFGGIPQNF
                     GNGPGSLNAPPGFGSGPPGLGSVPGHLSGPPAFGPGPGPGPIHIGGPPGFGASSGKPG
                     PTIIKVQNMPFTVSIDEILDFFYGYQVIPGSVCLKYNEKGMPTGEAMVAFESRDEATA
                     AVIDLNDRPIGSRKVKLVLG"
     regulatory      3694..3699
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Rbm12"
                     /gene_synonym="5730420G12Rik; 9430070C08Rik; mKIAA0765;
                     SWAN"
                     /note="hexamer: AATAAA"
     polyA_site      3714
                     /gene="Rbm12"
                     /gene_synonym="5730420G12Rik; 9430070C08Rik; mKIAA0765;
                     SWAN"
                     /note="major polyA site"
     regulatory      6294..6299
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Rbm12"
                     /gene_synonym="5730420G12Rik; 9430070C08Rik; mKIAA0765;
                     SWAN"
                     /note="hexamer: AATAAA"
     polyA_site      6327
                     /gene="Rbm12"
                     /gene_synonym="5730420G12Rik; 9430070C08Rik; mKIAA0765;
                     SWAN"
     regulatory      6597..6602
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Rbm12"
                     /gene_synonym="5730420G12Rik; 9430070C08Rik; mKIAA0765;
                     SWAN"
                     /note="hexamer: AATAAA"
     regulatory      6613..6618
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Rbm12"
                     /gene_synonym="5730420G12Rik; 9430070C08Rik; mKIAA0765;
                     SWAN"
                     /note="hexamer: AATAAA"
     polyA_site      6618
                     /gene="Rbm12"
                     /gene_synonym="5730420G12Rik; 9430070C08Rik; mKIAA0765;
                     SWAN"
     polyA_site      6640
                     /gene="Rbm12"
                     /gene_synonym="5730420G12Rik; 9430070C08Rik; mKIAA0765;
                     SWAN"
ORIGIN      
        1 attttgtgaa gcggctgtgg aggtgttggc tgcagtgggc tccgggaaag ccgttcgggc
       61 tggggctgtc ggccgcaggg ctgaggcact cgcgcggggg gtaactcggg tctgggttct
      121 ggtgccgcgc aagctctccc cgtctaaaag ttggttttaa ttggttgccc acaggattga
      181 cttggcctct gcttcttaag aaaatacatc tcttgtttta caggtgtgtg tggtttcagc
      241 gcagcatggc tgtggtcatc cgtttgcaag gtctcccaat tgtggcgggg accatggaca
      301 ttcgccactt cttctctgga ttaaccatcc ccgatggggg cgtgcatatt gtagggggtg
      361 aactgggtga ggctttcatc gtttttgcca ctgatgaaga tgcaaggctt ggtatgatgc
      421 gcacaggtgg tactattaaa gggtcaaaag taacactatt attgagtagt aaaacagaaa
      481 tgcaaaatat gattgaactg agtcgtaggc gttttgaaac tgccaactta gatattccgc
      541 cagcaaatgc tagtagatca ggaccaccac ctagctcagg gatgagcagc agggtgaact
      601 tgccagcaat agtacccaac tttaataatc cttcgccaag tgtagtaact gctaccactt
      661 ctgttcatga gagcaacaaa aacatacaga cattttccac agccagcgta ggaaccgctc
      721 ctccaagcat ggggacttct tttgggagcc caacgttcag ttcaaccatt ccaagtacag
      781 cttctccaat gaacacggtc ccaccgccac cgattcctcc aatcccagcg atgccatctt
      841 tgccaccgct gccatccatt cccccaatac cagttcctcc tccggtacca acattgcctc
      901 ctgtgccacc tgttcctccc attcccccag tcccttcggt gccacctatg accacactgc
      961 ctcctatgtc aggcatgcca cccttgaatc caccacctgt ggcaccttta cctgctggaa
     1021 tgaatggctc tggagcacct atcggtctga acaataatat gaatcctgtg tttctgggtc
     1081 cattaaatcc tgttaactct atacagatga attctcaaag cagcgtgaag tctcttccca
     1141 tcaaccctga tgatctgtat gtgagtgtgc atggaatgcc cttttctgca atggaaaatg
     1201 atgtcagaga gtttttccat gggctccgag tcgatgcagt gcatttgtta aaagatcatg
     1261 taggtcgaaa taatgggaat ggattggtta agtttctctc ccctcaagat acatttgaag
     1321 ctttgaaacg gaacagaatg ctgatgattc aacgctatgt ggaagtcagt cctgccacag
     1381 agagacagtg ggtagctgct ggaggtcata tcacttttaa gcaaagtatg gggccttctg
     1441 gacaagccca ccctcctcca cagacacttc caaggtcaaa atcgcccagt gggcagaaaa
     1501 ggtcaagatc aagatcacca catgaggctg gcttttgtgt ttacttaaaa gggctaccat
     1561 ttgaagcaga aaacaaacat gtcattgatt tttttaagaa gttggatatt gtggaagata
     1621 gtatttatat agcttatgga cccaatggga aagcaactgg tgaaggcttt gtagaattta
     1681 ggaatgatgc tgactataag gctgctctct gtcgtcataa acaatacatg ggcaatcgct
     1741 ttattcaagt tcatccaata actaagaaag gtatgcttga aaagatagat atgattcgaa
     1801 aacgacttca gaacttcagc tatgaccaga gggaactggt gttaaatcca gagggggaag
     1861 tcagttctgc caaagtctgt gcccatataa caaacattcc attcagcatc accaagatgg
     1921 atgttcttca gttcctagaa ggaatcccag tggatgagag tgctgtgcat gttcttgttg
     1981 ataacaatgg gcaaggtcta gggcaagcat tggttcagtt taaaactgaa gatgacgcac
     2041 ataaatctga acacttacac cgtaaaaagc tgaatgggag agaagctttt gttcatatag
     2101 ttaccctaga agatatgaga gagattgaga aaaatccccc agcccaagga aaaaagggtc
     2161 taaagatatc tgttccaggt aatcctgcag taccagtgat acctagtgca gggatgcctg
     2221 ctgctggaat tcccactgcc gggataccag gggctggatt gcctagtgct ggaatgcctg
     2281 gtgctgggat gcccagctct ggaatgcctg gtcctggaat gcccggtccc ggaatacccg
     2341 gtgcgggaat acctggtccc gcaatgcctg gtcctgcaat gcctggtccc gcaatgcctg
     2401 gtcccgcaat gcccggtccc gcaatgcccg gtcccgcaat gcccggtccc gcaatgcccg
     2461 gtcccgcaat gcccggtccc gcaatacctg gtcccgcaat acctggtccc gcaatacctg
     2521 gtgctggcat ccccagtgca ggaggagaag agcatgtctt cttgactgta ggatcaaagg
     2581 aggccaataa tgggccacca tttaacttcc ctggtaattt tggtgggccc aatgcctttg
     2641 ggccaccact cccccctcca ggattagggg gtgcctttgg tgatgttagg cctgttatgc
     2701 cttcggttgg aaatagtggt ttgcctggcc taggactgga agttccaggt tttggaggtg
     2761 caccaaataa tataagtggg ccatcaggat ttggggggat ccctcagaac tttggaaatg
     2821 gcccaggtag tttaaatgct cctcctggtt ttggaagtgg accccctggt cttggaagtg
     2881 ttcctgggca tttgagtggg cctccagcct ttgggcctgg gcctgggcct ggcccaatcc
     2941 atattggggg tccccctggc tttggagcta gctctggaaa accaggacct acaataatta
     3001 aggtgcagaa catgcctttt actgtatcta ttgatgaaat tttagatttc ttttatggtt
     3061 atcaagtaat tccaggttca gtatgtttaa aatacaatga aaaaggtatg cctacaggtg
     3121 aagccatggt ggcctttgaa tctcgggatg aagccacagc tgctgtcatt gacttaaatg
     3181 ataggcctat aggttcaaga aaggtaaaac ttgttttagg gtagccgttc acatcagttc
     3241 cttatggggt atatctttat tttgctgtga ttaatgcatc cagattgttt tcctagtagt
     3301 tccaggttag aacctgtgga ttgtttcaat tgcagataga ttggtttcta taacacagag
     3361 cattggttgg ctgttttaca actcacagaa taaacattgc aatttgttac agtaaagcta
     3421 tctggagaga acacaaaaat aattttggca tacagtagag accatttgta attctcgatg
     3481 atcaaggaat ctagattggt tttcttttat accacatggg atgaagaaaa ttgaaacgta
     3541 taaatagaaa cgtgagtaga gctcgtggag ggggctcatg ccagtgatgg cattggaagt
     3601 tggctacttt tgccatttgt tttaaagctg gacatacttg ctttgttata gggtcaaagc
     3661 tttgtctgaa accttcattt tcttttaaaa ttgaataaag tctctgtatc cagattcatt
     3721 gtatgtacct ttattgcttc tggagggttc ttgctgtata gacggccctg cttcagtgtt
     3781 gctgcttcat cttcctaatt gaccacttgt aatcagtaca ccattttgtt agtttttcat
     3841 taatttctaa tataaaaact ccacacttgt ggtttgtgct aaataaccct gaactttgtg
     3901 attaatgtca cacttatgat tgtgtgaaat gactttgacc ataaaaataa actatggagt
     3961 cctctactga cattatttgg tttgaccgcc aagttttatt tagtttaggg agtttaaaat
     4021 ttgttcatat tgtttggatg acaatgaaaa tcagaaacca cttagtaatc agtgtttagg
     4081 tatttgattt gaaatccttt actgtgatgg actaatttag caaattgttt ttgtcccaat
     4141 ttatgtgaat tttggaacaa agagattcat aggaaagagc attgtatttc ggagtataaa
     4201 actgaaatga aagtggtagt tttgttagca gtagtagtgc agaatgaaag atccttaagt
     4261 tggatcatag gttgatgtgt gtttaattct gttaatttgg aggctttttg gtgcagttgt
     4321 ttgatcatga gcctgttcac aaaaattctt tatgcagagt cttaagtatc aatgtcagaa
     4381 gagagaattg aggtcactcc gtgcatttta tattcttttc cttttggcaa tcaggatact
     4441 aagatagaat cttcggttgg ctaaatgtcc tttcccttaa aagcatttgg tttttcacat
     4501 cttgttcact gacaccttac ggctcttttt ctaaatttaa gatgcttgaa agctgtttca
     4561 catttcacat gacatacaga attggagatt gatgaataat aacgggaaat aaatagtatc
     4621 tttcacataa tgtagctctg gtttcaaaca ccaatatcga gaagtctgca tttattttta
     4681 aaagaagcat ttctcacata cattatatat attatatata tatacatgta tgtatgcgtg
     4741 tatacacatg cacacacaac tgtatgtatg tatgtctatg tagtgccttt tttgtgttct
     4801 gagggagtgg taccctgagg tctcgtcgtg tagttttaga gttaagagtg gcaacagtct
     4861 cgtgtgtgga aagtgtggaa agcctctcca atactgcgat ggtcttggag gagagacagt
     4921 atggtggtct gttcagggaa agggttgtgc aggctttgaa aagtggctgc attgtgaatc
     4981 acttgataac tcacaaacac aatttgcttg aaagatagct actgcctcaa aaagcaatat
     5041 gtttatatgt gatgttcttt gttaaggaat catttctcgt ttgaagacat agtgtgaacg
     5101 cttcagaact gttttgggct tcttattcca actgcaggtt tattttcccc attggaaact
     5161 gactatattt tagaaaaaat gattgttgga aggtgaaaat tttttatcct ttctcacaat
     5221 ttattttggt tgtatcttcg tacatgctta ttaaatattt catacactca attgcaacta
     5281 ttttgttatt tctacatctt agataaatgc taaaaagaaa aacttggttc tcactgttca
     5341 ttaaataaat taagaaaata gtgttggtat agaaatcaga gagaattgtg ttccgcatcc
     5401 cttgaatcac aacagagctt gttgtgaaat gtaactaaat gctctgccct ctggaacttg
     5461 agtttgtatg tttgagacag acctaattgc taagtatatt gttttatctt gtttgggcat
     5521 tgaagtttta gtttttgttt ttgttttaat aaccatgaaa atgtgttcta tcaaactatt
     5581 catacctctc gtcagacaat ttttttttcc agaactagtc ttgatataga tttgcattta
     5641 cgtaattttt ccatttgtat ggttatgaag gctttgtaaa gctttgctca aagtgtgttt
     5701 gtaaacactg tcaaggtatt ctcaatttca tgtgtaaatt ttattgtctg ttttcggtga
     5761 cttacattta tggaaaagaa tatttcatta ggcttaattt gtttctcctg agtttttatt
     5821 agtgtttatt tttcttttgg ttttatagga gtagagaaac ctgcaaatgt attgtaaaat
     5881 aagcaaattg taaattttta aaacgagtgc ccgacttagc tcataagcat aacttggagg
     5941 tgttgcctgt gtttatactg tctggatgta cagttctgta cagtggctgc tgtaggctct
     6001 gtcttaatgc aacagtgtta cgtgaaacgt agttcctgac ttgttatttt acgttgctaa
     6061 agcattgaca attaaagctg cactaggaaa tgtcaacctt acagagagta atacttagtg
     6121 tagcgtaggt cagtcttgat ctgcttgatg aaaatctagg cgttcgtaca tatatggaag
     6181 taagcaagca ctcgtggttt ttaggtggaa atactcacct tgcacaaaaa tgaggaaaca
     6241 aaagctaact caaacttcat tttcctgaac tctgtgattg atgacgtgtg taaaataaaa
     6301 tgcactcagt ttgaaagcgt tggaaaatga gtgaagaccg taatctgtcc aatgactccc
     6361 agtctgtgct ctggggacgt ttctggcggt gctcactgag tacctttccc actcacaatt
     6421 gccatgtgta agttatttta cttcagctgt tttactggca gttctgtagt ccaaactttt
     6481 gaaatcaagt acagccaaaa ggctgttgac agtgtgacca caacattgcc agcacatcct
     6541 actttggcat cacttagcaa tttttgttta taaagaagaa gtcttggata ctgttcaata
     6601 aacttgtcac aaaataaagg ctgatgcttt aatgctttaa
//
