LOCUS       NM_153196               1026 bp    mRNA    linear   ROD 02-JUN-2024
DEFINITION  Mus musculus ribokinase (Rbks), transcript variant 1, mRNA.
ACCESSION   NM_153196
VERSION     NM_153196.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1026)
  AUTHORS   Bulusu,V., Prior,N., Snaebjornsson,M.T., Kuehne,A., Sonnen,K.F.,
            Kress,J., Stein,F., Schultz,C., Sauer,U. and Aulehla,A.
  TITLE     Spatiotemporal Analysis of a Glycolytic Activity Gradient Linked to
            Mouse Embryo Mesoderm Development
  JOURNAL   Dev Cell 40 (4), 331-341 (2017)
   PUBMED   28245920
REFERENCE   2  (bases 1 to 1026)
  AUTHORS   Bowman,C.E., Zhao,L., Hartung,T. and Wolfgang,M.J.
  TITLE     Requirement for the Mitochondrial Pyruvate Carrier in Mammalian
            Development Revealed by a Hypomorphic Allelic Series
  JOURNAL   Mol Cell Biol 36 (15), 2089-2104 (2016)
   PUBMED   27215380
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 1026)
  AUTHORS   Liu,Y., Li,T.R., Xu,C. and Xu,T.
  TITLE     Ribose Accelerates Gut Motility and Suppresses Mouse Body Weight
            Gaining
  JOURNAL   Int J Biol Sci 12 (6), 701-709 (2016)
   PUBMED   27194947
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 1026)
  AUTHORS   Ivliev,A.E., 't Hoen,P.A., van Roon-Mom,W.M., Peters,D.J. and
            Sergeeva,M.G.
  TITLE     Exploring the transcriptome of ciliated cells using in silico
            dissection of human tissues
  JOURNAL   PLoS One 7 (4), e35618 (2012)
   PUBMED   22558177
REFERENCE   5  (bases 1 to 1026)
  AUTHORS   Chen,T.S., Tan,S.S., Yeo,R.W., Teh,B.J., Luo,R., Li,G. and Lim,S.K.
  TITLE     Delineating biological pathways unique to embryonic stem
            cell-derived insulin-producing cell lines from their
            noninsulin-producing progenitor cell lines
  JOURNAL   Endocrinology 151 (8), 3600-3610 (2010)
   PUBMED   20501672
REFERENCE   6  (bases 1 to 1026)
  AUTHORS   Lin,Q., Donahue,S.L., Moore-Jarrett,T., Cao,S., Osipovich,A.B. and
            Ruley,H.E.
  TITLE     Mutagenesis of diploid mammalian genes by gene entrapment
  JOURNAL   Nucleic Acids Res 34 (20), e139 (2006)
   PUBMED   17062627
REFERENCE   7  (bases 1 to 1026)
  AUTHORS   HIATT,H.H.
  TITLE     Glycogen formation via the pentose phosphate pathway in mice in
            vivo
  JOURNAL   J Biol Chem 224 (2), 851-859 (1957)
   PUBMED   13405914
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC114613.12.
            
            On Mar 9, 2023 this sequence version replaced NM_153196.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC023339.1, SRR13862062.14730.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164135 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-106               AC114613.12        25456-25561
            107-239             AC114613.12        49626-49758
            240-303             AC114613.12        56147-56210
            304-366             AC114613.12        57290-57352
            367-531             AC114613.12        63000-63164
            532-623             AC114613.12        71171-71262
            624-812             AC114613.12        75162-75350
            813-1026            AC114613.12        98415-98628
FEATURES             Location/Qualifiers
     source          1..1026
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="5"
                     /map="5 17.27 cM"
     gene            1..1026
                     /gene="Rbks"
                     /gene_synonym="5230400M11Rik; RBSK; RK"
                     /note="ribokinase"
                     /db_xref="GeneID:71336"
                     /db_xref="MGI:MGI:1918586"
     exon            1..106
                     /gene="Rbks"
                     /gene_synonym="5230400M11Rik; RBSK; RK"
                     /inference="alignment:Splign:2.1.0"
     CDS             15..986
                     /gene="Rbks"
                     /gene_synonym="5230400M11Rik; RBSK; RK"
                     /EC_number="2.7.1.15"
                     /note="isoform 1 is encoded by transcript variant 1"
                     /codon_start=1
                     /product="ribokinase isoform 1"
                     /protein_id="NP_694876.1"
                     /db_xref="CCDS:CCDS19187.1"
                     /db_xref="GeneID:71336"
                     /db_xref="MGI:MGI:1918586"
                     /translation="MAACGEPGRPWQEEEAAAVVVVGSCMTDLVSLTSRLPKTGETIH
                     GHEFFIGFGGKGANQCVQAARLGAKAAIVCKVGNDSFGNDYIENLKQNHISTEFTYQT
                     RDAATGTASIIVNNEGQNIIVIVAGANLFLNSEDLKKAASVISRAKVMICQLEISPAA
                     SLEALTMARRSGVKTLFNPAPAMADLDPQFYTLSSIFCCNESEAEILTGHAVSDPTTA
                     GKAAMILLERGCQVVVITLGASGCVILSQAEPVPKHIPTEAVKAVDTTGAGDSFVGAL
                     AFYLAYYPNLSLEEMLKRSNFIAAVSVQATGTQSSYPYKKDLPLALF"
     exon            107..239
                     /gene="Rbks"
                     /gene_synonym="5230400M11Rik; RBSK; RK"
                     /inference="alignment:Splign:2.1.0"
     exon            240..303
                     /gene="Rbks"
                     /gene_synonym="5230400M11Rik; RBSK; RK"
                     /inference="alignment:Splign:2.1.0"
     exon            304..366
                     /gene="Rbks"
                     /gene_synonym="5230400M11Rik; RBSK; RK"
                     /inference="alignment:Splign:2.1.0"
     exon            367..531
                     /gene="Rbks"
                     /gene_synonym="5230400M11Rik; RBSK; RK"
                     /inference="alignment:Splign:2.1.0"
     exon            532..623
                     /gene="Rbks"
                     /gene_synonym="5230400M11Rik; RBSK; RK"
                     /inference="alignment:Splign:2.1.0"
     exon            624..812
                     /gene="Rbks"
                     /gene_synonym="5230400M11Rik; RBSK; RK"
                     /inference="alignment:Splign:2.1.0"
     exon            813..1026
                     /gene="Rbks"
                     /gene_synonym="5230400M11Rik; RBSK; RK"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1007..1012
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Rbks"
                     /gene_synonym="5230400M11Rik; RBSK; RK"
                     /note="hexamer: AATACA"
     polyA_site      1026
                     /gene="Rbks"
                     /gene_synonym="5230400M11Rik; RBSK; RK"
                     /note="major polyA site"
ORIGIN      
        1 gagcaggatt agtaatggcg gcgtgtgggg agcccgggag gccctggcag gaggaggagg
       61 cagcagcggt ggtagtggtg ggttcctgca tgaccgacct ggtcagtctt acttctcgct
      121 tgccaaaaac tggagaaacc atccatggac atgagttttt tattggcttt ggaggaaaag
      181 gtgccaacca gtgtgtccaa gctgcgcgac tgggagcaaa ggcggccata gtctgcaagg
      241 ttggcaacga ttcttttggc aatgattaca tagaaaactt aaaacaaaat catatttcta
      301 cagagtttac atatcagacc agagatgcag ctacaggaac agcctccata attgtcaata
      361 atgaaggcca gaatatcatc gtcatagtgg ctggagcaaa tctgtttttg aattctgaag
      421 acttgaagaa ggcagccagt gtcattagcc gagccaaagt gatgatatgc cagctagaaa
      481 taagcccggc agcttctctg gaagctctga caatggcccg caggagtgga gtgaaaacct
      541 tgttcaaccc agctccagcc atggctgacc tggaccccca gttctatacc ctctccagta
      601 ttttctgctg caacgagagc gaggctgaga ttttaacagg ccacgcagtg agtgacccca
      661 ccacggctgg gaaggctgca atgattctcc tagaacgggg ctgccaggtt gtggtcatca
      721 ccttaggggc ttcaggatgc gtgatactgt cacaggctga gcctgttcca aagcacattc
      781 ccactgaagc tgtcaaggct gtagacacca cgggtgctgg tgacagtttt gtgggagcgc
      841 tggccttcta cctggcttac tacccaaatc tgtccttgga agaaatgctc aagagatcca
      901 atttcatcgc tgcagtcagt gtacaggcca cgggaacaca gtcctcttat ccatacaaaa
      961 aagacctccc tcttgctcta ttttgactac tgctaacccc caaataaata caatctggaa
     1021 agtaaa
//
