LOCUS       NM_015754               2183 bp    mRNA    linear   ROD 01-JUN-2024
DEFINITION  Mus musculus retinoblastoma binding protein 9, serine hydrolase
            (Rbbp9), mRNA.
ACCESSION   NM_015754 XM_992135
VERSION     NM_015754.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2183)
  AUTHORS   Adachi,T., Yasuda,K., Muto,T., Serada,S., Yoshimoto,T., Ishii,K.J.,
            Kuroda,E., Araki,K., Ohmuraya,M., Naka,T. and Nakanishi,K.
  TITLE     Lung fibroblasts produce IL-33 in response to stimulation with
            retinoblastoma-binding protein 9 via production of prostaglandin E2
  JOURNAL   Int Immunol 32 (10), 637-652 (2020)
   PUBMED   32484881
  REMARK    GeneRIF: Lung fibroblasts produce IL-33 in response to stimulation
            with retinoblastoma-binding protein 9 via production of
            prostaglandin E2.
REFERENCE   2  (bases 1 to 2183)
  AUTHORS   Choo,H.J., Cutler,A., Rother,F., Bader,M. and Pavlath,G.K.
  TITLE     Karyopherin Alpha 1 Regulates Satellite Cell Proliferation and
            Survival by Modulating Nuclear Import
  JOURNAL   Stem Cells 34 (11), 2784-2797 (2016)
   PUBMED   27434733
REFERENCE   3  (bases 1 to 2183)
  AUTHORS   Sheehan,S., Tsaih,S.W., King,B.L., Stanton,C., Churchill,G.A.,
            Paigen,B. and DiPetrillo,K.
  TITLE     Genetic analysis of albuminuria in a cross between C57BL/6J and
            DBA/2J mice
  JOURNAL   Am J Physiol Renal Physiol 293 (5), F1649-F1656 (2007)
   PUBMED   17804484
REFERENCE   4  (bases 1 to 2183)
  AUTHORS   Zhao,Y., Ransom,J.F., Li,A., Vedantham,V., von Drehle,M.,
            Muth,A.N., Tsuchihashi,T., McManus,M.T., Schwartz,R.J. and
            Srivastava,D.
  TITLE     Dysregulation of cardiogenesis, cardiac conduction, and cell cycle
            in mice lacking miRNA-1-2
  JOURNAL   Cell 129 (2), 303-317 (2007)
   PUBMED   17397913
REFERENCE   5  (bases 1 to 2183)
  AUTHORS   Cassie,S., Koturbash,I., Hudson,D., Baker,M., Ilnytskyy,Y.,
            Rodriguez-Juarez,R., Weber,E. and Kovalchuk,O.
  TITLE     Novel retinoblastoma binding protein RBBP9 modulates sex-specific
            radiation responses in vivo
  JOURNAL   Carcinogenesis 27 (3), 465-474 (2006)
   PUBMED   16272168
  REMARK    GeneRIF: first report of very pronounced and producible sex
            differences in expresion of RBBP9; RBBP9 expression inversely
            correlated with RB phosphorylation
REFERENCE   6  (bases 1 to 2183)
  AUTHORS   Geiger,H., Rennebeck,G. and Van Zant,G.
  TITLE     Regulation of hematopoietic stem cell aging in vivo by a distinct
            genetic element
  JOURNAL   Proc Natl Acad Sci U S A 102 (14), 5102-5107 (2005)
   PUBMED   15788535
REFERENCE   7  (bases 1 to 2183)
  AUTHORS   Woitach,J.T., Hong,R., Keck,C.L., Zimonjic,D.B., Popescu,N.C. and
            Thorgeirsson,S.S.
  TITLE     Assignment of the Bog gene (RBBP9) to syntenic regions of mouse
            chromosome 2G1-H1 and human chromosome 20p11.2 by fluorescence in
            situ hybridization
  JOURNAL   Cytogenet Cell Genet 85 (3-4), 252-253 (1999)
   PUBMED   10449909
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BY256564.1, AK076944.1 and BC050201.1.
            
            On or before May 4, 2006 this sequence version replaced
            XM_992135.1, NM_015754.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC050201.1, AK076944.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164131, SAMN01164139
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-15                BY256564.1         12-26
            16-2124             AK076944.1         11-2119
            2125-2183           BC050201.1         2061-2119
FEATURES             Location/Qualifiers
     source          1..2183
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="2"
                     /map="2 71.02 cM"
     gene            1..2183
                     /gene="Rbbp9"
                     /gene_synonym="Bog"
                     /note="retinoblastoma binding protein 9, serine hydrolase"
                     /db_xref="GeneID:26450"
                     /db_xref="MGI:MGI:1347074"
     exon            1..180
                     /gene="Rbbp9"
                     /gene_synonym="Bog"
                     /inference="alignment:Splign:2.1.0"
     CDS             82..642
                     /gene="Rbbp9"
                     /gene_synonym="Bog"
                     /note="RBBP-9; B5T-overexpressed gene protein;
                     retinoblastoma-binding protein 9"
                     /codon_start=1
                     /product="putative hydrolase RBBP9"
                     /protein_id="NP_056569.2"
                     /db_xref="CCDS:CCDS16821.1"
                     /db_xref="GeneID:26450"
                     /db_xref="MGI:MGI:1347074"
                     /translation="MASPNKAVIVPGNGGGDVATHGWYGWVKKGLEQIPGFQCLAKNM
                     PDPITARESIWLPFMETELHCDEKTIIIGHSSGAIAAMRYAETHQVYALVLVSAYTSD
                     LGDENERASGYFSRPWQWEKIKANCPHIVQFGSTDDPFLPWKEQQEVADRLDAKLYKF
                     TDRGHFQNTEFHELISVVKSMLKGPE"
     exon            181..223
                     /gene="Rbbp9"
                     /gene_synonym="Bog"
                     /inference="alignment:Splign:2.1.0"
     exon            224..329
                     /gene="Rbbp9"
                     /gene_synonym="Bog"
                     /inference="alignment:Splign:2.1.0"
     exon            330..415
                     /gene="Rbbp9"
                     /gene_synonym="Bog"
                     /inference="alignment:Splign:2.1.0"
     exon            416..2160
                     /gene="Rbbp9"
                     /gene_synonym="Bog"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2136..2141
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Rbbp9"
                     /gene_synonym="Bog"
                     /note="hexamer: AATAAA"
     polyA_site      2160
                     /gene="Rbbp9"
                     /gene_synonym="Bog"
                     /note="major polyA site"
ORIGIN      
        1 agtgcaggct ctgggccgga tgtagtcttg gtctgagagc tgctggtcca agctgggcaa
       61 gggtctccca cgtctacatt catggcgtcc cccaacaagg cagtgattgt tcccgggaac
      121 ggaggcgggg atgtggccac ccacggctgg tacggctggg tgaaaaaggg gctggagcag
      181 attcctggtt tccagtgttt ggctaaaaac atgcctgacc caattacagc gcgagagagc
      241 atctggctgc ccttcatgga gacagagctg cactgtgacg agaagaccat catcataggc
      301 cacagttccg gggccatcgc agccatgagg tatgcagaga cacatcaggt atatgctctc
      361 gtattggtgt ctgcatacac atcagacttg ggagatgaaa atgagcgtgc aagtgggtac
      421 ttcagccgcc cctggcagtg ggagaagatc aaggccaact gccctcacat tgtacagttt
      481 ggctctactg atgacccctt ccttccctgg aaggaacaac aagaagtagc agataggctg
      541 gacgccaaat tgtacaaatt cactgaccgt ggtcactttc agaacacaga gttccatgaa
      601 ctgattagtg tggtgaagtc tatgctgaaa ggaccagaat agtcaggatg gctcctgctc
      661 tctaacaagc cagggtggag gagaataata acagcaactc ttctcaccag cactagacag
      721 ttaagctgca gaagcgcctg aacaaacccg tttgaacact cacaccaagt taccagcact
      781 ttcagttccc acagaactta aatcttcctg aaaagctact aactatagca gtaggtttcc
      841 tgtttgataa gggacacaga gtttgtttac ctatcctgtt gatgcagaga gagagaagaa
      901 tccaggactt gacggtcatg gtggtgtgtc cctgtaatta cttcagagaa agcaggggat
      961 caggaaggga aggctagctt gaccctgtct aagaaaagaa agaacaagac agcccaggtc
     1021 tcctgagtct cattccaaat tttaactcaa taggtttagc aagatgcaat ctacttctga
     1081 ggccccagta cttataaacg tgaggaaggt ggatcttgaa tttgaggcct gtgtaggcct
     1141 agtaaagtaa aaccctatct cagaataaaa caaaacaaaa ccaaaaaaca ggttttcatt
     1201 caacttatat gagtgacagt ttttcctttt tgaaataaaa tttttctctt actggagaaa
     1261 gaaaacatga ttcgaggccc cgaatgttat tagaactcaa aactctagct ggtctttcag
     1321 gctggctcaa gagagtaatc tcacacttgg gtcttgatca ccgacatccc tgaccccact
     1381 acatccccag gtctttctga caagttgaga gagactgaca tctatggatg ttcagtaagg
     1441 agctgtatgg gcagatatct gcatagcctg tcacctgggt atcagctata tatgactggc
     1501 aggattaggt catggggaag tactaaaata tagacacata agcactcatg tcctttttta
     1561 actgggggaa tatgtatgta tgtatataca atccctacat gaattatggt agctggcaac
     1621 agcattgtaa ttcaaagatt tgcaaatgct gcaagataaa gaccaggtca tccatttgtg
     1681 agttggaggt aaacattttt agattctcta tgaatccaag aaaagcctaa gacaaccaaa
     1741 atgaacataa tagtaaaggt ggaagacaag ggagcaacct gtactgtgtt attaagttct
     1801 aagtgtcctc aaaagaacct ttttctagaa gaccagattt caattcccag aaacgacatg
     1861 gtggctctgt aatgggatct gacgccctct tctgctaagt ctgaagacac cgtgtactca
     1921 catacataaa ataaactatg ccaggttaat tctatagagt tcagcctctt gtagagagta
     1981 ttcaagcaac actgccgagt cttctcatat tcactcacat aaacaacccc tttttaatac
     2041 tactttttat attgtatata ttcaatgtat aaaatggttt gatgattcca tttccactgg
     2101 tttataaagt actttgacca aatgtaaaaa gatataataa aaaatgttta tttcctagta
     2161 aaaaaaaaaa aaaaaaaaaa aaa
//
