LOCUS       NM_009826               7046 bp    mRNA    linear   ROD 28-JAN-2025
DEFINITION  Mus musculus RB1-inducible coiled-coil 1 (Rb1cc1), mRNA.
ACCESSION   NM_009826
VERSION     NM_009826.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 7046)
  AUTHORS   Liu,H., Su,P., Li,Y., Hoover,A., Hu,S., King,S.A., Zhao,J.,
            Guan,J.L., Chen,S.Y., Zhao,Y., Tan,M. and Wu,X.
  TITLE     VAMP2 controls murine epidermal differentiation and carcinogenesis
            by regulation of nucleophagy
  JOURNAL   Dev Cell 59 (15), 2005-2016 (2024)
   PUBMED   38810653
REFERENCE   2  (bases 1 to 7046)
  AUTHORS   Feng,S., McNehlan,M.E., Kinsella,R.L., Sur Chowdhury,C.,
            Chavez,S.M., Naik,S.K., McKee,S.R., Van Winkle,J.A., Dubey,N.,
            Samuels,A., Swain,A., Cui,X., Hendrix,S.V., Woodson,R.,
            Kreamalmeyer,D., Smirnov,A., Artyomov,M.N., Virgin,H.W., Wang,Y.T.
            and Stallings,C.L.
  TITLE     Autophagy promotes efficient T cell responses to restrict high-dose
            Mycobacterium tuberculosis infection in mice
  JOURNAL   Nat Microbiol 9 (3), 684-697 (2024)
   PUBMED   38413834
REFERENCE   3  (bases 1 to 7046)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   4  (bases 1 to 7046)
  AUTHORS   Tscherner,A.K., McClatchie,T., Macaulay,A.D. and Baltz,J.M.
  TITLE     Relationship of quantitative reverse transcription polymerase chain
            reaction (RT-PCR) to RNA Sequencing (RNAseq) transcriptome
            identifies mouse preimplantation embryo reference genesdagger
  JOURNAL   Biol Reprod 109 (5), 601-617 (2023)
   PUBMED   37669129
REFERENCE   5  (bases 1 to 7046)
  AUTHORS   Yang,F., Kalantari,S., Ruan,B., Sun,S., Bian,Z. and Guan,J.L.
  TITLE     Autophagy inhibition prevents lymphatic malformation progression to
            lymphangiosarcoma by decreasing osteopontin and Stat3 signaling
  JOURNAL   Nat Commun 14 (1), 978 (2023)
   PUBMED   36813768
  REMARK    Publication Status: Online-Only
REFERENCE   6  (bases 1 to 7046)
  AUTHORS   Okazaki,N., Kikuno,R., Ohara,R., Inamoto,S., Hara,Y., Nagase,T.,
            Ohara,O. and Koga,H.
  TITLE     Prediction of the coding sequences of mouse homologues of KIAA
            gene: I. The complete nucleotide sequences of 100 mouse
            KIAA-homologous cDNAs identified by screening of terminal sequences
            of cDNA clones randomly sampled from size-fractionated libraries
  JOURNAL   DNA Res 9 (5), 179-188 (2002)
   PUBMED   12465718
REFERENCE   7  (bases 1 to 7046)
  AUTHORS   Chano,T., Ikegawa,S., Saito-Ohara,F., Inazawa,J., Mabuchi,A.,
            Saeki,Y. and Okabe,H.
  TITLE     Isolation, characterization and mapping of the mouse and human
            RB1CC1 genes
  JOURNAL   Gene 291 (1-2), 29-34 (2002)
   PUBMED   12095676
REFERENCE   8  (bases 1 to 7046)
  AUTHORS   Chano,T., Ikegawa,S., Kontani,K., Okabe,H., Baldini,N. and Saeki,Y.
  TITLE     Identification of RB1CC1, a novel human gene that can induce RB1 in
            various human cells
  JOURNAL   Oncogene 21 (8), 1295-1298 (2002)
   PUBMED   11850849
REFERENCE   9  (bases 1 to 7046)
  AUTHORS   Pfeuffer,T., Goebel,W., Laubinger,J., Bachmann,M. and Kuhn,M.
  TITLE     LaXp180, a mammalian ActA-binding protein, identified with the
            yeast two-hybrid system, co-localizes with intracellular Listeria
            monocytogenes
  JOURNAL   Cell Microbiol 2 (2), 101-114 (2000)
   PUBMED   11207567
REFERENCE   10 (bases 1 to 7046)
  AUTHORS   Maucuer,A., Camonis,J.H. and Sobel,A.
  TITLE     Stathmin interaction with a putative kinase and coiled-coil-forming
            protein domains
  JOURNAL   Proc Natl Acad Sci U S A 92 (8), 3100-3104 (1995)
   PUBMED   7724523
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AB070619.1, CN720888.1, AK041038.1 and AK033709.1.
            
            On Apr 14, 2009 this sequence version replaced NM_009826.3.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AB070619.1, AB050017.2 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849381, SAMN00849382
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-358               AB070619.1         1-358
            359-673             CN720888.1         284-598
            674-2875            AB070619.1         674-2875
            2876-4363           AK041038.1         664-2151
            4364-6517           AB070619.1         4364-6517
            6518-7046           AK033709.1         1013-1541
FEATURES             Location/Qualifiers
     source          1..7046
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="1"
                     /map="1 1.89 cM"
     gene            1..7046
                     /gene="Rb1cc1"
                     /gene_synonym="2900055E04Rik; 5930404L04Rik; Cc1; FIP200;
                     LaXp180"
                     /note="RB1-inducible coiled-coil 1"
                     /db_xref="GeneID:12421"
                     /db_xref="MGI:MGI:1341850"
     exon            1..296
                     /gene="Rb1cc1"
                     /gene_synonym="2900055E04Rik; 5930404L04Rik; Cc1; FIP200;
                     LaXp180"
                     /inference="alignment:Splign:2.1.0"
     exon            297..406
                     /gene="Rb1cc1"
                     /gene_synonym="2900055E04Rik; 5930404L04Rik; Cc1; FIP200;
                     LaXp180"
                     /inference="alignment:Splign:2.1.0"
     exon            407..521
                     /gene="Rb1cc1"
                     /gene_synonym="2900055E04Rik; 5930404L04Rik; Cc1; FIP200;
                     LaXp180"
                     /inference="alignment:Splign:2.1.0"
     CDS             451..5217
                     /gene="Rb1cc1"
                     /gene_synonym="2900055E04Rik; 5930404L04Rik; Cc1; FIP200;
                     LaXp180"
                     /note="200 kDa FAK family kinase-interacting protein;
                     coiled-coil-forming protein 1; FAK family
                     kinase-interacting protein of 200 kDa"
                     /codon_start=1
                     /product="RB1-inducible coiled-coil protein 1"
                     /protein_id="NP_033956.2"
                     /db_xref="CCDS:CCDS35507.1"
                     /db_xref="GeneID:12421"
                     /db_xref="MGI:MGI:1341850"
                     /translation="MKLYVFLVNTGTTLTFDTELTVQTVADLKHAIQSKYKIAIQHQV
                     LVVNGGECMAADRRVCTYSAGTDTNPIFLFNKEMILCDRAPAIPKATFSTENDMEIKV
                     EESLMMPAVFHTVASRTQLAVEMYDVAKKLCSFCEGLVHDEHLQHQGWAAIMANLEDC
                     SNSYQKLLFKFESIYSDYLQSIEDIKLKLTHLGTAVSVMAKIPLLECLTRHSYRECLG
                     RPDSLNEHEGSEKAEMKRSTELVLSPDMPRTTNTSLVTSFHKSMEHVAPDPTGTERGK
                     ELRESCQSTVQQEEASVDAKDSDLPFFNVSLLDWINVQDRPNDVESLVRKCFDSMSRL
                     DPKIIQPFMLECHQTIAKLDNQNMKAIKGLEDRLYALDQMIASCSRLVNEQKELAQGF
                     LANQMRAENLKDASVLPDLCLSHANQLMIMLQNHRKLLDIKQKCTTAKQELANNLHVR
                     LKWCCFVMLHADQDGEKLQALLRLVIELLERVRIVEALSTVPQMYCLAVVEVVRRKMF
                     IKHYREWAGALVKDGKQLYEAEKSKRESFGKLFRKSFLRNRLFKGLDSWPSSFCTQKP
                     RKFDCELPDISLKDLQFLQSFCPSEVQPFLRVPLLCDFEPLHQHVLALHNLVKAAQSL
                     DEMSQTITDLLNEQKVSTSQASPQSAASPRIESTTGITTTTSPKTPPPLTVQDTLCPA
                     VCPLEELSPDSIDAHTFDFETISHPNTEQPVHQASIDLDSLAESPESDFMSAVNEFVI
                     EENLSSPNPISDPQSPEMMVESLYSSVINAIDSRRMQDTSTRGNEGFGDRAALHVQLE
                     KCRAAAQDSHSSIQTIKDDLCHFRTFVQKEQCDLANYLKCTAVEIRNIIEKVKCSLEI
                     TLKEKHQQELQSLKIEYECKLDALVKDSEENVNKILKLKENLVSLEEALQNKDNEFTS
                     IKHEKDAIVCVQQEKDQKLLEMEKIMHTQHCEIKELKQSREMALEDLKKLHDEKIESL
                     RAEFQCLEQNHLKELEDTLHIRHTQEFEKVMTDHNMSLEKLKKENQQRIDQMLESHAS
                     TIQEKEQQLQELKLKVSDLSDMRCKLEVELALKEAETDEIKILLEESRTQQKEMLKSL
                     LEQETENLRTEISKLNQKIHDNNESYQVGLSELRALMTIEKDQCISELISRHEEESNI
                     LKAELDNVTSLHRQAYEIEKKLKEQIVELQTRLNSELSALEKQKDEKITQQEEKYEAL
                     IQNLEKDKERLVKNHEQDKEHLIQELNFEKNKAVQTALDEFKVERELVEKELLEKVKH
                     LENQIAKTPAFESAREDSSSLVAELQEKLQEEKAKFLEQLEEQEKRKNEEMQNVRTSL
                     IAEQQTNFNTVLTREKMRKENIINDLSDKLKSTMQQQERDKDLIESLSEDRARLLEEK
                     KQLEEEVSKLRTSSFLSSAPVAAAPELYGACAPELPGEPERSVMETADEGRLDSAMET
                     SMMSVQENMLSEEKQRIMLLERTLQLKEEENKRLNQRLMSQSLSSVSSRHSEKIAIRD
                     FQVGDLVLIILDERHDNYVLFTVSPTLYFLHSESLPALDLKPGEGASGASRRPWVLGK
                     VMEKEYCQAKKAQNRFKVPLGTKFYRVKAVSWNKKV"
     exon            522..648
                     /gene="Rb1cc1"
                     /gene_synonym="2900055E04Rik; 5930404L04Rik; Cc1; FIP200;
                     LaXp180"
                     /inference="alignment:Splign:2.1.0"
     exon            649..819
                     /gene="Rb1cc1"
                     /gene_synonym="2900055E04Rik; 5930404L04Rik; Cc1; FIP200;
                     LaXp180"
                     /inference="alignment:Splign:2.1.0"
     exon            820..1022
                     /gene="Rb1cc1"
                     /gene_synonym="2900055E04Rik; 5930404L04Rik; Cc1; FIP200;
                     LaXp180"
                     /inference="alignment:Splign:2.1.0"
     exon            1023..1449
                     /gene="Rb1cc1"
                     /gene_synonym="2900055E04Rik; 5930404L04Rik; Cc1; FIP200;
                     LaXp180"
                     /inference="alignment:Splign:2.1.0"
     exon            1450..1620
                     /gene="Rb1cc1"
                     /gene_synonym="2900055E04Rik; 5930404L04Rik; Cc1; FIP200;
                     LaXp180"
                     /inference="alignment:Splign:2.1.0"
     exon            1621..1805
                     /gene="Rb1cc1"
                     /gene_synonym="2900055E04Rik; 5930404L04Rik; Cc1; FIP200;
                     LaXp180"
                     /inference="alignment:Splign:2.1.0"
     exon            1806..1992
                     /gene="Rb1cc1"
                     /gene_synonym="2900055E04Rik; 5930404L04Rik; Cc1; FIP200;
                     LaXp180"
                     /inference="alignment:Splign:2.1.0"
     exon            1993..2074
                     /gene="Rb1cc1"
                     /gene_synonym="2900055E04Rik; 5930404L04Rik; Cc1; FIP200;
                     LaXp180"
                     /inference="alignment:Splign:2.1.0"
     exon            2075..2136
                     /gene="Rb1cc1"
                     /gene_synonym="2900055E04Rik; 5930404L04Rik; Cc1; FIP200;
                     LaXp180"
                     /inference="alignment:Splign:2.1.0"
     exon            2137..2240
                     /gene="Rb1cc1"
                     /gene_synonym="2900055E04Rik; 5930404L04Rik; Cc1; FIP200;
                     LaXp180"
                     /inference="alignment:Splign:2.1.0"
     exon            2241..2367
                     /gene="Rb1cc1"
                     /gene_synonym="2900055E04Rik; 5930404L04Rik; Cc1; FIP200;
                     LaXp180"
                     /inference="alignment:Splign:2.1.0"
     exon            2368..4259
                     /gene="Rb1cc1"
                     /gene_synonym="2900055E04Rik; 5930404L04Rik; Cc1; FIP200;
                     LaXp180"
                     /inference="alignment:Splign:2.1.0"
     exon            4260..4425
                     /gene="Rb1cc1"
                     /gene_synonym="2900055E04Rik; 5930404L04Rik; Cc1; FIP200;
                     LaXp180"
                     /inference="alignment:Splign:2.1.0"
     exon            4426..4534
                     /gene="Rb1cc1"
                     /gene_synonym="2900055E04Rik; 5930404L04Rik; Cc1; FIP200;
                     LaXp180"
                     /inference="alignment:Splign:2.1.0"
     exon            4535..4775
                     /gene="Rb1cc1"
                     /gene_synonym="2900055E04Rik; 5930404L04Rik; Cc1; FIP200;
                     LaXp180"
                     /inference="alignment:Splign:2.1.0"
     exon            4776..4824
                     /gene="Rb1cc1"
                     /gene_synonym="2900055E04Rik; 5930404L04Rik; Cc1; FIP200;
                     LaXp180"
                     /inference="alignment:Splign:2.1.0"
     exon            4825..4872
                     /gene="Rb1cc1"
                     /gene_synonym="2900055E04Rik; 5930404L04Rik; Cc1; FIP200;
                     LaXp180"
                     /inference="alignment:Splign:2.1.0"
     exon            4873..4931
                     /gene="Rb1cc1"
                     /gene_synonym="2900055E04Rik; 5930404L04Rik; Cc1; FIP200;
                     LaXp180"
                     /inference="alignment:Splign:2.1.0"
     exon            4932..5068
                     /gene="Rb1cc1"
                     /gene_synonym="2900055E04Rik; 5930404L04Rik; Cc1; FIP200;
                     LaXp180"
                     /inference="alignment:Splign:2.1.0"
     exon            5069..5139
                     /gene="Rb1cc1"
                     /gene_synonym="2900055E04Rik; 5930404L04Rik; Cc1; FIP200;
                     LaXp180"
                     /inference="alignment:Splign:2.1.0"
     exon            5140..7046
                     /gene="Rb1cc1"
                     /gene_synonym="2900055E04Rik; 5930404L04Rik; Cc1; FIP200;
                     LaXp180"
                     /inference="alignment:Splign:2.1.0"
     regulatory      5271..5276
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Rb1cc1"
                     /gene_synonym="2900055E04Rik; 5930404L04Rik; Cc1; FIP200;
                     LaXp180"
                     /note="hexamer: GATAAA"
     polyA_site      5290
                     /gene="Rb1cc1"
                     /gene_synonym="2900055E04Rik; 5930404L04Rik; Cc1; FIP200;
                     LaXp180"
                     /note="major polyA site"
     regulatory      6089..6094
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Rb1cc1"
                     /gene_synonym="2900055E04Rik; 5930404L04Rik; Cc1; FIP200;
                     LaXp180"
                     /note="hexamer: AATAAA"
     polyA_site      6110
                     /gene="Rb1cc1"
                     /gene_synonym="2900055E04Rik; 5930404L04Rik; Cc1; FIP200;
                     LaXp180"
                     /note="major polyA site"
     regulatory      6499..6504
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Rb1cc1"
                     /gene_synonym="2900055E04Rik; 5930404L04Rik; Cc1; FIP200;
                     LaXp180"
                     /note="hexamer: AATAAA"
     polyA_site      6520
                     /gene="Rb1cc1"
                     /gene_synonym="2900055E04Rik; 5930404L04Rik; Cc1; FIP200;
                     LaXp180"
     regulatory      6661..6666
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Rb1cc1"
                     /gene_synonym="2900055E04Rik; 5930404L04Rik; Cc1; FIP200;
                     LaXp180"
                     /note="hexamer: AATATA"
     polyA_site      6684
                     /gene="Rb1cc1"
                     /gene_synonym="2900055E04Rik; 5930404L04Rik; Cc1; FIP200;
                     LaXp180"
ORIGIN      
        1 ccgagtcgac aataacaaac cccacggcgg ccgcgaccca gccctgccaa gctctcagtg
       61 cctcggccgg cggactcggg tccccgcgcg gagccgaggg gccggagcag cggctgcgcc
      121 cgactcccat ccttccgggc ctcgccgggt actcggcggc tgggcgccga cggttgtgtc
      181 ggttggcggc gccgcagggg cggttgatag ccgccgccga ggccagggcg gcggcagaag
      241 atggtgcgga gggccgccgg ctgtgttgct gccgcgggcg gaggaggcgc tgccggttct
      301 ctgagtttca ccagtaatgc cactcagttg ccaatatcaa gcaagcgcat ataagacact
      361 tgtaatcttt taagaaaagt agtacttctc ttcacagtat ctggcggatc aacactggag
      421 ggtgaggtgt cagcttccag aaagatcatc atgaagttat atgtgtttct ggttaacacc
      481 ggaaccacgc tgacatttga cactgagcta actgtgcaaa ctgtggctga tcttaagcat
      541 gccattcaaa gcaaatacaa gattgctatt cagcaccagg ttctggtggt caatggagga
      601 gaatgcatgg ctgcagatcg aagagtgtgt acttacagcg ctgggacgga cacaaatcca
      661 atttttcttt ttaataaaga aatgatctta tgtgaccgtg cacctgctat tcctaaagct
      721 accttttcaa cagaaaatga catggaaata aaagttgaag agtctcttat gatgcctgca
      781 gttttccaca ctgttgcttc aaggacacag cttgcagtgg aaatgtatga cgttgccaag
      841 aagctctgct ctttctgtga agggcttgtc catgatgaac atcttcagca ccaaggctgg
      901 gctgcaatca tggccaatct ggaggactgt tcaaattcat accaaaaact tcttttcaag
      961 tttgaaagta tttattctga ttatcttcaa tccatagaag acatcaagtt aaaacttact
     1021 catttaggaa ctgctgtttc agtaatggcc aagattccac tattggagtg cctaaccaga
     1081 catagttaca gggaatgttt gggaagaccg gattctttga atgaacatga aggctcagag
     1141 aaagctgaga tgaaaagatc tactgaactg gtgctctctc ctgatatgcc tagaacaacg
     1201 aacacatcct tggtaacctc atttcacaag tcaatggagc atgtagctcc agatcccacc
     1261 ggtactgaac gtggcaaaga acttagggaa tcttgtcaaa gtactgtcca gcaagaagaa
     1321 gcttcagtgg atgctaaaga cagtgatctg ccttttttta atgtttcttt gttagactgg
     1381 ataaatgttc aagatagacc caatgatgtg gaatctctgg tcaggaagtg ctttgattct
     1441 atgagcaggc ttgacccaaa gattattcaa ccatttatgt tagaatgcca tcaaactatt
     1501 gccaaacttg ataatcagaa tatgaaagcc attaaagggc ttgaagatcg gctgtatgcc
     1561 ttggaccaga tgattgctag ctgtagccgg ctggtaaatg aacagaaaga gcttgctcag
     1621 ggatttttag ctaatcagat gagagctgaa aacttgaagg atgcatctgt gttacctgat
     1681 ctgtgtctga gtcatgcaaa tcaactaatg attatgttgc aaaaccacag aaaactgttg
     1741 gatattaaac agaagtgcac cactgccaaa caagagctag caaacaatct ccacgtcaga
     1801 ctgaagtggt gttgttttgt gatgcttcat gctgatcaag atggagaaaa actgcaggca
     1861 ctgctccgcc ttgtaataga gctgttagaa agagtcagaa ttgttgaggc tcttagtaca
     1921 gttcctcaga tgtattgcct agctgttgtt gaggttgtaa gaagaaaaat gttcattaaa
     1981 cactacagag agtgggctgg tgctttagtc aaagacggaa aacaactata tgaagctgaa
     2041 aagtcaaaaa gggaatcctt tgggaaatta tttaggaagt cctttttaag aaatcgtctg
     2101 tttaaaggac tggactcctg gccttcctca ttttgtactc agaagcctcg aaaatttgac
     2161 tgtgaacttc cagatatatc attaaaagat ttacagtttc ttcaatcatt ttgtccttca
     2221 gaagtgcagc cattcctcag ggtcccctta ctttgtgact ttgaacctct acaccagcat
     2281 gtacttgccc tacataattt ggtaaaagca gcacaaagtt tggatgaaat gtcacagact
     2341 attacagatc tcctaaatga acaaaaggta tccacaagtc aggcatcccc acagtcagct
     2401 gcttctccaa gaatagaaag tacaacaggc attacaacca ctacctcacc aaaaactcct
     2461 cctccactaa ctgttcagga caccttatgt ccggcagtgt gtcccttaga agaattatct
     2521 ccagatagta tcgatgctca tacatttgat ttcgaaacca tctcccatcc aaacacagaa
     2581 caacctgttc accaagcttc tatagacttg gattcattag cagaaagccc tgagtctgac
     2641 tttatgtctg ctgtgaatga gtttgtgata gaagaaaatt tatcgtctcc aaaccctata
     2701 agtgatccac aaagtccaga aatgatggtg gagtcacttt actcttcagt catcaatgca
     2761 atagatagta ggcgtatgca agacacaagt acacgtggaa acgagggctt tggggatcgg
     2821 gctgctctac atgtccagct ggagaaatgc agagctgctg cacaagactc tcacagcagt
     2881 atacaaacca tcaaggacga tctgtgccat ttcagaacat ttgtacaaaa agaacagtgt
     2941 gacttagcaa attatttaaa atgtacagct gtagaaataa gaaatattat tgaaaaagta
     3001 aaatgttctc tagaaataac actaaaggaa aagcatcagc aagaactcca atctttaaaa
     3061 attgagtatg aatgtaaact tgatgctcta gtaaaagaca gtgaagaaaa tgtaaataaa
     3121 attttaaaat tgaaagaaaa tttagtatcc cttgaagagg ctttacaaaa taaagacaat
     3181 gaattcactt cgattaaaca tgaaaaggat gctattgtct gtgtgcagca agaaaaggat
     3241 cagaagttgt tagagatgga aaagataatg catactcaac attgtgaaat taaagaactg
     3301 aagcagtcac gagagatggc attagaagac ctgaaaaagc tgcatgatga aaaaatcgag
     3361 tcattgagag ctgaatttca gtgcttagaa caaaatcacc tgaaggaatt agaggacaca
     3421 ctgcacatca ggcacacaca ggagtttgag aaagttatga cagaccacaa tatgtctttg
     3481 gagaaattaa aaaaagaaaa tcagcaaaga attgaccaga tgctagaatc tcatgcctca
     3541 actattcagg aaaaagagca acagctgcag gagttgaaac tcaaagtttc tgacttgtca
     3601 gacatgagat gtaagttaga ggttgaactt gcactaaagg aagcagaaac agatgagata
     3661 aagatcttgt tggaagagag cagaacacag cagaaggaaa tgctgaagtc tttacttgaa
     3721 caagagaccg aaaacttaag aacagaaata agtaaactaa accaaaaaat tcatgataat
     3781 aatgagagtt accaggtggg tttgtcagag ttaagagctt taatgacaat tgaaaaagat
     3841 cagtgcattt cagagttaat cagtagacat gaagaagaat ctaatatact taaggctgaa
     3901 ttagacaatg ttacatcttt gcatcgccaa gcatatgaaa tagaaaaaaa actgaaagaa
     3961 caaatagttg aattgcagac tagattgaac tcagaattga gtgctcttga aaaacagaaa
     4021 gatgaaaaaa taacccaaca agaagagaag tatgaagcac ttatccagaa ccttgagaaa
     4081 gacaaggaga gactggtcaa gaaccacgag caagacaaag aacacttaat tcaggagctt
     4141 aattttgaaa aaaacaaagc tgttcaaact gcactagatg aatttaaggt ggagagagaa
     4201 cttgttgaga aagagttatt agaaaaagtt aaacatcttg agaatcaaat agccaaaact
     4261 cctgcctttg agtcagccag agaagattct tcaagcttag ttgcggaact tcaagagaaa
     4321 cttcaagaag aaaaagctaa gtttctggaa caacttgaag aacaagagaa aagaaagaat
     4381 gaggaaatgc aaaatgtcag aacctctttg attgctgagc agcagaccaa ctttaacaca
     4441 gtcttaacaa gagagaaaat gaggaaagaa aacataataa atgatcttag tgataagcta
     4501 aaaagtacaa tgcagcagca agagcgggat aaagatttga tagagtcgct ctctgaggac
     4561 cgagctcgtt tgcttgaaga gaagaagcag cttgaagagg aagtgagtaa actccgcact
     4621 agcagttttc tttcctcagc acctgtggct gcagccccag agctctatgg tgcgtgtgca
     4681 cctgagctcc caggggagcc agagagatca gtcatggaga cggcagatga aggaagactg
     4741 gattccgcaa tggagacaag catgatgtct gtccaagaaa acatgttatc tgaagagaag
     4801 cagaggatca tgctcctaga acggacattg cagttgaaag aagaagaaaa caagcggtta
     4861 aatcaaagac tgatgtctca gagtttgtcc tcagtctctt caaggcattc tgaaaaaata
     4921 gccattagag attttcaggt gggagatttg gttctcatca tcctagatga gcggcacgac
     4981 aattatgtat tgtttactgt tagtcctact ttatattttc tgcactcaga gtctcttcct
     5041 gccctggatc tcaaaccagg tgagggagct tcaggtgcat ctagaagacc ctgggtcctt
     5101 gggaaagtaa tggaaaagga atactgtcaa gccaaaaagg cacaaaacag atttaaagtt
     5161 cctttgggga caaagtttta cagagtgaaa gctgtgtcat ggaataagaa agtatagcca
     5221 cagaagaaat ctctacatct cataccattt ttgatttgtc ctccagtgct gataaactac
     5281 tctaaaaaca gctggccatt gttgggtttt tttttgttgt ttgtttgttt gtttgttttt
     5341 acaaaagtca acataacaat atacttcatt ggtggactgc acttaccttt taagtggcta
     5401 catcttagga acaataaatt tattaaaatt cttggctgaa tcaaaatggt tttgttttgt
     5461 ttccacccaa ataactagaa attcggacca aaatagatgt tttccaaggg cagagcctgc
     5521 actgtggctt gtgactagcc tcattagttg cctgttaata aacattagct gaatagttac
     5581 cagtgttgtt accagcattt gtcctcttgt gaattcaaga gtcctcgcac tctttaacat
     5641 gttctttata aaatgtataa acccttccaa actatttaaa gaggagtgtt attgcatgca
     5701 gataatcata attttgagtt tgcctcagaa gactactaaa gcaaatttgt tcattttttt
     5761 ttaaaaaaat gccctttaat gtttcaaaaa aaaataacag tgtaatttga ctgactttaa
     5821 gatcagccat aaataatgag cagtcttcaa aagcactttt cacacagatc atctgggctc
     5881 cagggaggaa gagtctgtgc cactgatgtt ttcaagtgca ggactcactc aaacctctca
     5941 gcatcttagg actgtttcaa gtaatcatat tgatgaactc gtaattcatg gttgaccttc
     6001 agaagaagat attcattgta tattaacatt tagaggtcat ttaaataaca aaagtctgta
     6061 ttgtaaagga cctgtacaat tttaagacaa taaagaattg aaagtgtaaa tgtgtgtgcc
     6121 ttttaaaggt tacattttaa atatattgcg tgatttctgg gaaaggtgaa aaaaatgttc
     6181 tgtatcaaag agaaacctgt ttattaaaaa atgttgtttg tatcctatgt aacagggtga
     6241 agtggtgttc tgtggaacag aaccatgtaa actcaaggtt taaaagctgg cactgaacaa
     6301 agatattgaa gtagctaggc tagttgattg gaaagagttt cttcagggtt gttgttagca
     6361 gtaataaatg attctttttc agaaatattt aatttctcca taaaaataag ttggatattt
     6421 ttataaatat gtaatctaat agaatgaaaa tggaataaac atagtgtata gaatacctaa
     6481 ttcaaaaaca tattaatgaa taaacgaaca aatgatttca tgtttctatt cagtccttca
     6541 atgacatctt tatatataga ctacaagtgt aacatgactt tatgtatttt taaaacagtt
     6601 gtatttgtga ttgagtctgt tagtgcagtc tatttcactt aattggtgct cttcagattt
     6661 aatatatggt tttatgctgt ggaattactg tgtgttctga cacactaact ctctttcgtt
     6721 aacactgagt cttgtggtcg ttgattgtct ttgttaccca gtactttcat attcatctta
     6781 ccagtgttca cacacatgtt ccaagcaagt gagaactaaa aagattttgt tacaaagaaa
     6841 acaaaacaat tccagaagcc taaattcatt gagcttttgt ttttacatag ttaaaggcaa
     6901 tatgaacttt gcagctagaa tgaatacctg actttcagtc tcagatgtgg cttttagata
     6961 aagttccaca aatggaccca ttgtctgatg tctaaaacag ggtactggaa cctatgtaat
     7021 atagtttgca ctttcaatgc aaaaat
//
